Berberine radiosensitizes human esophageal cancer cells by downregulating homologous recombination repair protein RAD51

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Liu, Qiao ^a   Jiang, Haiyan ^a   Liu, Zhaojian ^a   Wang, Yu ^a   Zhao, Minnan ^a   Hao, Chunyan ^b   Feng, Shuai ^a   Guo, Haiyang ^a   Xu, Bing ^a   Yang, Qifeng ^b   Gong, Yaoqin ^a   Shao, Changshun ^a  

^a Shandong University   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; PACLITAXEL; RAD51 PROTEIN; RADIOSENSITIZING AGENT; H2AFX PROTEIN, HUMAN; HISTONE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CANCER RESISTANCE; CANCER TISSUE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; DRUG EFFICACY; DRUG POTENCY; ESOPHAGUS CANCER; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; ONCOGENE; ONCOGENE RAD51; RADIOSENSITIVITY; RNA INTERFERENCE; X RAY; CELL CULTURE; CELL STRAIN HEK293; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; ESOPHAGUS TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HOMOLOGOUS RECOMBINATION; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; RADIATION EXPOSURE; RECOMBINATION REPAIR; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE; WESTERN BLOTTING;

BERBERINE; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DNA BREAKS, DOUBLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, DRUG; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HISTONES; HOMOLOGOUS RECOMBINATION; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; RAD51 RECOMBINASE; RADIATION-SENSITIZING AGENTS; RECOMBINATIONAL DNA REPAIR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 79961192394     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023427     Document Type: Article

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