-
1
-
-
33746851541
-
First national epidemiological survey on the prevalence of obesity and abdominal fat distribution in Greek adults
-
Kapantais E, Tzotzas T, Ioannidis I, et al. First national epidemiological survey on the prevalence of obesity and abdominal fat distribution in Greek adults. Ann Nutr Metab. 2006; 50: 330-338.
-
(2006)
Ann Nutr Metab
, vol.50
, pp. 330-338
-
-
Kapantais, E.1
Tzotzas, T.2
Ioannidis, I.3
-
2
-
-
21444453624
-
The prevalence of the metabolic syndrome in Greece: The MetS-Greece Multicentre Study
-
Athyros VG, Bouloukos VI, Pehlivanidis AN, et al. The prevalence of the metabolic syndrome in Greece: the MetS-Greece Multicentre Study. Diabetes Obes Metab. 2005; 7: 397-405.
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 397-405
-
-
Athyros, V.G.1
Bouloukos, V.I.2
Pehlivanidis, A.N.3
-
3
-
-
0036923205
-
Overweight, obesity and fat distribution in 50- to 64-year-old participants in the European Prospective Investigation into Cancer and Nutrition (EPIC)
-
Haftenberger M, Lahmann PH, Panico S, et al. Overweight, obesity and fat distribution in 50- to 64-year-old participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Public Health Nutr. 2002; 5: 1147-1162.
-
(2002)
Public Health Nutr
, vol.5
, pp. 1147-1162
-
-
Haftenberger, M.1
Lahmann, P.H.2
Panico, S.3
-
4
-
-
18944394486
-
Epidemiology of overweight and obesity in a Greek adult population: The ATTICA Study
-
Panagiotakos DB, Pitsavos C, Chrysohoou C, et al. Epidemiology of overweight and obesity in a Greek adult population: the ATTICA Study. Obes Res. 2004; 12: 1914-1920.
-
(2004)
Obes Res
, vol.12
, pp. 1914-1920
-
-
Panagiotakos, D.B.1
Pitsavos, C.2
Chrysohoou, C.3
-
5
-
-
33747114039
-
Preventing cardiovascular disease and diabetes: A call to action from the American Diabetes Association and the American Heart Association
-
Eckel RH, Kahn R, Robertson RM, Rizza RA. Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association. Circulation. 2006; 113: 2943-2946.
-
(2006)
Circulation
, vol.113
, pp. 2943-2946
-
-
Eckel, R.H.1
Kahn, R.2
Robertson, R.M.3
Rizza, R.A.4
-
6
-
-
64649083354
-
The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis
-
Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009; 9: 88.
-
(2009)
BMC Public Health
, vol.9
, pp. 88
-
-
Guh, D.P.1
Zhang, W.2
Bansback, N.3
Amarsi, Z.4
Birmingham, C.L.5
Anis, A.H.6
-
7
-
-
0036681988
-
Obesity and the risk of heart failure
-
Kenchaiah S, Evans JC, Levy D, et al. Obesity and the risk of heart failure. N Engl J Med. 2002; 347: 305-313.
-
(2002)
N Engl J Med
, vol.347
, pp. 305-313
-
-
Kenchaiah, S.1
Evans, J.C.2
Levy, D.3
-
8
-
-
73349094732
-
Forecasting the effects of obesity and smoking on U.S. life expectancy
-
Stewart ST, Cutler DM, Rosen AB. Forecasting the effects of obesity and smoking on U.S. life expectancy. N Engl J Med. 2009; 361: 2252-2260.
-
(2009)
N Engl J Med
, vol.361
, pp. 2252-2260
-
-
Stewart, S.T.1
Cutler, D.M.2
Rosen, A.B.3
-
9
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003; 112: 1796-1808.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
10
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
Weisberg SP, Hunter D, Huber R, et al. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest. 2006; 116: 115-124.
-
(2006)
J Clin Invest
, vol.116
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
-
11
-
-
0036678477
-
Adipose tissue mass can be regulated through the vasculature
-
Rupnick MA, Panigrahy D, Zhang CY, et al. Adipose tissue mass can be regulated through the vasculature. Proc Natl Acad Sci U S A. 2002; 99: 10730-10735.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10730-10735
-
-
Rupnick, M.A.1
Panigrahy, D.2
Zhang, C.Y.3
-
12
-
-
0033537013
-
Elevated C-reactive protein levels in overweight and obese adults
-
Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Elevated C-reactive protein levels in overweight and obese adults. JAMA. 1999; 282: 2131-2135.
-
(1999)
JAMA
, vol.282
, pp. 2131-2135
-
-
Visser, M.1
Bouter, L.M.2
McQuillan, G.M.3
Wener, M.H.4
Harris, T.B.5
-
13
-
-
24944454234
-
Release of Creactive protein in response to inflammatory cytokines by human adipocytes: Linking obesity to vascular inflammation
-
Calabro P, Chang DW, Willerson JT, Yeh ET. Release of Creactive protein in response to inflammatory cytokines by human adipocytes: linking obesity to vascular inflammation. J Am Coll Cardiol. 2005; 46: 1112-1113.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 1112-1113
-
-
Calabro, P.1
Chang, D.W.2
Willerson, J.T.3
Yeh, E.T.4
-
14
-
-
0035717514
-
Elevated C-reactive protein: Another component of the atherothrombotic profile of abdominal obesity
-
Lemieux I, Pascot A, Prud'homme D, et al. Elevated C-reactive protein: another component of the atherothrombotic profile of abdominal obesity. Arterioscler Thromb Vasc Biol. 2001; 21: 961-967.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 961-967
-
-
Lemieux, I.1
Pascot, A.2
Prud'homme, D.3
-
15
-
-
0035716609
-
Energy restriction and weight loss on very-low-fat diets reduce C-reactive protein concentrations in obese, healthy women
-
Heilbronn LK, Noakes M, Clifton PM. Energy restriction and weight loss on very-low-fat diets reduce C-reactive protein concentrations in obese, healthy women. Arterioscler Thromb Vasc Biol. 2001; 21: 968-970.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 968-970
-
-
Heilbronn, L.K.1
Noakes, M.2
Clifton, P.M.3
-
16
-
-
2942670689
-
Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
-
Ridker PM, Wilson PW, Grundy SM. Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation. 2004; 109: 2818-2825.
-
(2004)
Circulation
, vol.109
, pp. 2818-2825
-
-
Ridker, P.M.1
Wilson, P.W.2
Grundy, S.M.3
-
17
-
-
52949112332
-
C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression
-
Turu MM, Slevin M, Matou S, et al. C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression. BMC Cell Biol. 2008; 9: 47.
-
(2008)
BMC Cell Biol
, vol.9
, pp. 47
-
-
Turu, M.M.1
Slevin, M.2
Matou, S.3
-
18
-
-
0043075885
-
Increased thrombosis after arterial injury in human C-reactive proteintransgenic mice
-
Danenberg HD, Szalai AJ, Swaminathan RV, et al. Increased thrombosis after arterial injury in human C-reactive proteintransgenic mice. Circulation. 2003; 108: 512-515.
-
(2003)
Circulation
, vol.108
, pp. 512-515
-
-
Danenberg, H.D.1
Szalai, A.J.2
Swaminathan, R.V.3
-
19
-
-
1042301971
-
C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice
-
Paul A, Ko KW, Li L, et al. C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2004; 109: 647-655.
-
(2004)
Circulation
, vol.109
, pp. 647-655
-
-
Paul, A.1
Ko, K.W.2
Li, L.3
-
20
-
-
54049133705
-
Neointimal formation is reduced after arterial injury in human crp transgenic mice
-
Danenberg HD, Grad E, Swaminathan RV, et al. Neointimal formation is reduced after arterial injury in human crp transgenic mice. Atherosclerosis. 2008; 201: 85-91.
-
(2008)
Atherosclerosis
, vol.201
, pp. 85-91
-
-
Danenberg, H.D.1
Grad, E.2
Swaminathan, R.V.3
-
21
-
-
20444419422
-
Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice
-
Hirschfield GM, Gallimore JR, Kahan MC, et al. Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice. Proc Natl Acad Sci U S A. 2005; 102: 8309-8314.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8309-8314
-
-
Hirschfield, G.M.1
Gallimore, J.R.2
Kahan, M.C.3
-
22
-
-
0025299388
-
''Portal'' adipose tissue as a generator of risk factors for cardiovascular disease and diabetes
-
Björntorp P. "Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes. Arteriosclerosis. 1990; 10: 493-496.
-
(1990)
Arteriosclerosis
, vol.10
, pp. 493-496
-
-
Björntorp, P.1
-
23
-
-
2042480671
-
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
-
Fain JN, Madan AK, Hiler ML, Cheema P, Bahouth SW. Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology. 2004; 145: 2273-2282.
-
(2004)
Endocrinology
, vol.145
, pp. 2273-2282
-
-
Fain, J.N.1
Madan, A.K.2
Hiler, M.L.3
Cheema, P.4
Bahouth, S.W.5
-
24
-
-
40149093610
-
Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: The Framingham Heart Study
-
Rosito GA, Massaro JM, Hoffmann U, et al. Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study. Circulation. 2008; 117: 605-613.
-
(2008)
Circulation
, vol.117
, pp. 605-613
-
-
Rosito, G.A.1
Massaro, J.M.2
Hoffmann, U.3
-
25
-
-
64849115634
-
Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: The Framingham Heart Study
-
Mahabadi AA, Massaro JM, Rosito GA, et al. Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. Eur Heart J. 2009; 30: 850-856.
-
(2009)
Eur Heart J
, vol.30
, pp. 850-856
-
-
Mahabadi, A.A.1
Massaro, J.M.2
Rosito, G.A.3
-
26
-
-
77954312890
-
Association of pericoronary fat volume with atherosclerotic plaque burden in the underlying coronary artery: A segment analysis
-
Mahabadi AA, Reinsch N, Lehmann N, et al. Association of pericoronary fat volume with atherosclerotic plaque burden in the underlying coronary artery: A segment analysis. Atherosclerosis. 2010; 211: 195-199.
-
(2010)
Atherosclerosis
, vol.211
, pp. 195-199
-
-
Mahabadi, A.A.1
Reinsch, N.2
Lehmann, N.3
-
27
-
-
77649197301
-
Adipokines in periaortic and epicardial adipose tissue: Differential expression and relation to atherosclerosis
-
Spiroglou SG, Kostopoulos CG, Varakis JN, Papadaki HH. Adipokines in periaortic and epicardial adipose tissue: differential expression and relation to atherosclerosis. J Atheroscler Thromb. 2010; 17: 115-130.
-
(2010)
J Atheroscler Thromb
, vol.17
, pp. 115-130
-
-
Spiroglou, S.G.1
Kostopoulos, C.G.2
Varakis, J.N.3
Papadaki, H.H.4
-
28
-
-
70349554744
-
Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets
-
Lohmann C, Schäfer N, von Lukowicz T, et al. Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets. Atherosclerosis. 2009; 207: 360-367.
-
(2009)
Atherosclerosis
, vol.207
, pp. 360-367
-
-
Lohmann, C.1
Schäfer, N.2
von Lukowicz, T.3
-
29
-
-
33644796221
-
Production of chemokines by perivascular adipose tissue: A role in the pathogenesis of atherosclerosis?
-
Henrichot E, Juge-Aubry CE, Pernin A, et al. Production of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis? Arterioscler Thromb Vasc Biol. 2005; 25: 2594-2599.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2594-2599
-
-
Henrichot, E.1
Juge-Aubry, C.E.2
Pernin, A.3
-
30
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 1998; 395: 763-770.
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
31
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med. 1995; 1: 1155-1161.
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
-
32
-
-
17844401180
-
Molecular and anatomical determinants of central leptin resistance
-
Münzberg H, Myers MG. Molecular and anatomical determinants of central leptin resistance. Nat Neurosci. 2005; 8: 566-570.
-
(2005)
Nat Neurosci
, vol.8
, pp. 566-570
-
-
Münzberg, H.1
Myers, M.G.2
-
33
-
-
75149193488
-
Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha) vbeta 5: Implications for angiogenesis in human obesity
-
Heida NM, Leifheit-Nestler M, Schroeter MR, et al. Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha) vbeta 5: implications for angiogenesis in human obesity. Arterioscler Thromb Vasc Biol. 2010; 30: 200-206.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 200-206
-
-
Heida, N.M.1
Leifheit-Nestler, M.2
Schroeter, M.R.3
-
34
-
-
0031775895
-
Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk
-
Leyva F, Godsland IF, Ghatei M, et al. Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk. Arterioscler Thromb Vasc Biol. 1998; 18: 928-933.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 928-933
-
-
Leyva, F.1
Godsland, I.F.2
Ghatei, M.3
-
35
-
-
58149098281
-
Leptin and coronary heart disease: Prospective study and systematic review
-
Sattar N, Wannamethee G, Sarwar N, et al. Leptin and coronary heart disease: prospective study and systematic review. J Am Coll Cardiol. 2009; 53: 167-175.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 167-175
-
-
Sattar, N.1
Wannamethee, G.2
Sarwar, N.3
-
36
-
-
34548665750
-
Expression of the leptin receptor in different types of vascular lesions
-
Schroeter MR, Schneiderman J, Schumann B, et al. Expression of the leptin receptor in different types of vascular lesions. Histochem Cell Biol. 2007; 128: 323-333.
-
(2007)
Histochem Cell Biol
, vol.128
, pp. 323-333
-
-
Schroeter, M.R.1
Schneiderman, J.2
Schumann, B.3
-
37
-
-
0347823193
-
Leptin promotes vascular remodeling and neointimal growth in mice
-
Schäfer K, Halle M, Goeschen C, et al. Leptin promotes vascular remodeling and neointimal growth in mice. Arterioscler Thromb Vasc Biol. 2004; 24: 112-117.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 112-117
-
-
Schäfer, K.1
Halle, M.2
Goeschen, C.3
-
38
-
-
31744435891
-
Recombinant leptin promotes atherosclerosis and thrombosis in apolipoprotein E-deficient mice
-
Bodary PF, Gu S, Shen Y, Hasty AH, Buckler JM, Eitzman DT. Recombinant leptin promotes atherosclerosis and thrombosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2005; 25: e119-122.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
-
-
Bodary, P.F.1
Gu, S.2
Shen, Y.3
Hasty, A.H.4
Buckler, J.M.5
Eitzman, D.T.6
-
39
-
-
33748970803
-
Leptin and atherosclerosis
-
Beltowski J. Leptin and atherosclerosis. Atherosclerosis. 2006; 189: 47-60.
-
(2006)
Atherosclerosis
, vol.189
, pp. 47-60
-
-
Beltowski, J.1
-
40
-
-
0035206659
-
Leptin stimulates rat aortic smooth muscle cell proliferation and migration
-
Oda A, Taniguchi T, Yokoyama M. Leptin stimulates rat aortic smooth muscle cell proliferation and migration. Kobe J Med Sci. 2001; 47: 141-150.
-
(2001)
Kobe J Med Sci
, vol.47
, pp. 141-150
-
-
Oda, A.1
Taniguchi, T.2
Yokoyama, M.3
-
41
-
-
0035179087
-
Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity
-
Konstantinides S, Schäfer K, Koschnick S, Loskutoff DJ. Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity. J Clin Invest. 2001; 108: 1533-1540.
-
(2001)
J Clin Invest
, vol.108
, pp. 1533-1540
-
-
Konstantinides, S.1
Schäfer, K.2
Koschnick, S.3
Loskutoff, D.J.4
-
42
-
-
0037012483
-
Effect of leptin on arterial thrombosis following vascular injury in mice
-
Bodary PF, Westrick RJ, Wickenheiser KJ, Shen YC, Eitzman DT. Effect of leptin on arterial thrombosis following vascular injury in mice. JAMA. 2002; 287: 1706-1709.
-
(2002)
JAMA
, vol.287
, pp. 1706-1709
-
-
Bodary, P.F.1
Westrick, R.J.2
Wickenheiser, K.J.3
Shen, Y.C.4
Eitzman, D.T.5
-
43
-
-
0032508682
-
Biological action of leptin as an angiogenic factor
-
Sierra-Honigmann MR, Nath AK, Murakami C, et al. Biological action of leptin as an angiogenic factor. Science. 1998; 281: 1683-1686.
-
(1998)
Science
, vol.281
, pp. 1683-1686
-
-
Sierra-Honigmann, M.R.1
Nath, A.K.2
Murakami, C.3
-
44
-
-
54049094100
-
Leptin enhances the recruitment of endothelial progenitor cells into neointimal lesions after vascular injury by promoting integrin-mediated adhesion
-
Schroeter MR, Leifheit M, Sudholt P, et al. Leptin enhances the recruitment of endothelial progenitor cells into neointimal lesions after vascular injury by promoting integrin-mediated adhesion. Circ Res. 2008; 103: 536-544.
-
(2008)
Circ Res
, vol.103
, pp. 536-544
-
-
Schroeter, M.R.1
Leifheit, M.2
Sudholt, P.3
-
45
-
-
0036063777
-
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
-
Maeda N, Shimomura I, Kishida K, et al. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med. 2002; 8: 731-737.
-
(2002)
Nat Med
, vol.8
, pp. 731-737
-
-
Maeda, N.1
Shimomura, I.2
Kishida, K.3
-
46
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T, Kamon J, Waki H, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med. 2001; 7: 941-946.
-
(2001)
Nat Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
-
47
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T, Kamon J, Minokoshi Y, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med. 2002; 8: 1288-1295.
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
-
49
-
-
0037135523
-
Disruption of adiponectin causes insulin resistance and neointimal formation
-
Kubota N, Terauchi Y, Yamauchi T, et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem. 2002; 277: 25863-25866.
-
(2002)
J Biol Chem
, vol.277
, pp. 25863-25866
-
-
Kubota, N.1
Terauchi, Y.2
Yamauchi, T.3
-
50
-
-
0037180472
-
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
-
Okamoto Y, Kihara S, Ouchi N, et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2002; 106: 2767-2770.
-
(2002)
Circulation
, vol.106
, pp. 2767-2770
-
-
Okamoto, Y.1
Kihara, S.2
Ouchi, N.3
-
51
-
-
0034641647
-
Adiponectin, an adipocytederived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
-
Ouchi N, Kihara S, Arita Y, et al. Adiponectin, an adipocytederived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation. 2000; 102: 1296-1301.
-
(2000)
Circulation
, vol.102
, pp. 1296-1301
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
-
52
-
-
0033613545
-
Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
-
Ouchi N, Kihara S, Arita Y, et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation. 1999; 100: 2473-2476.
-
(1999)
Circulation
, vol.100
, pp. 2473-2476
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
-
53
-
-
0035957040
-
Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
-
Ouchi N, Kihara S, Arita Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation. 2001; 103: 1057-1063.
-
(2001)
Circulation
, vol.103
, pp. 1057-1063
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
-
54
-
-
0037129861
-
Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor- BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell
-
Arita Y, Kihara S, Ouchi N, et al. Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor- BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation. 2002; 105: 2893-2898.
-
(2002)
Circulation
, vol.105
, pp. 2893-2898
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
-
55
-
-
1842864234
-
Plasma adiponectin levels and risk of myocardial infarction in men
-
Pischon T, Girman CJ, Hotamisligil GS, Rifai N, Hu FB, Rimm EB. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA. 2004; 291: 1730-1737.
-
(2004)
JAMA
, vol.291
, pp. 1730-1737
-
-
Pischon, T.1
Girman, C.J.2
Hotamisligil, G.S.3
Rifai, N.4
Hu, F.B.5
Rimm, E.B.6
-
56
-
-
0037432152
-
Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue
-
Ouchi N, Kihara S, Funahashi T, et al. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation. 2003; 107: 671-674.
-
(2003)
Circulation
, vol.107
, pp. 671-674
-
-
Ouchi, N.1
Kihara, S.2
Funahashi, T.3
-
57
-
-
33846989791
-
Association between plasma adiponectin levels and unstable coronary syndromes
-
Wolk R, Berger P, Lennon RJ, Brilakis ES, Davison DE, Somers VK. Association between plasma adiponectin levels and unstable coronary syndromes. Eur Heart J. 2007; 28: 292-298.
-
(2007)
Eur Heart J
, vol.28
, pp. 292-298
-
-
Wolk, R.1
Berger, P.2
Lennon, R.J.3
Brilakis, E.S.4
Davison, D.E.5
Somers, V.K.6
-
58
-
-
0036144672
-
Stromal cells are the main plasminogen activator inhibitor-1-producing cells in human fat: Evidence of differences between visceral and subcutaneous deposits
-
Bastelica D, Morange P, Berthet B, et al. Stromal cells are the main plasminogen activator inhibitor-1-producing cells in human fat: evidence of differences between visceral and subcutaneous deposits. Arterioscler Thromb Vasc Biol. 2002; 22: 173-178.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 173-178
-
-
Bastelica, D.1
Morange, P.2
Berthet, B.3
-
59
-
-
0032745726
-
Relationship between visceral fat and PAI-1 in overweight men and women before and after weight loss
-
Kockx M, Leenen R, Seidell J, Princen HM, Kooistra T. Relationship between visceral fat and PAI-1 in overweight men and women before and after weight loss. Thromb Haemost. 1999; 82: 1490-1496.
-
(1999)
Thromb Haemost
, vol.82
, pp. 1490-1496
-
-
Kockx, M.1
Leenen, R.2
Seidell, J.3
Princen, H.M.4
Kooistra, T.5
-
60
-
-
0031963703
-
The adipocyte and hemostatic balance in obesity: Studies of PAI-1
-
Loskutoff DJ, Samad F. The adipocyte and hemostatic balance in obesity: studies of PAI-1. Arterioscler Thromb Vasc Biol. 1998; 18: 1-6.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 1-6
-
-
Loskutoff, D.J.1
Samad, F.2
-
61
-
-
33947321575
-
uPAR-uPA-PAI-1 interactions and signaling: A vascular biologist's view
-
Binder BR, Mihaly J, Prager GW. uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view. Thromb Haemost. 2007; 97: 336-342.
-
(2007)
Thromb Haemost
, vol.97
, pp. 336-342
-
-
Binder, B.R.1
Mihaly, J.2
Prager, G.W.3
-
62
-
-
0030764551
-
PAI-1, obesity, insulin resistance and risk of cardiovascular events
-
Juhan-Vague I, Alessi MC. PAI-1, obesity, insulin resistance and risk of cardiovascular events. Thromb Haemost. 1997; 78: 656-660.
-
(1997)
Thromb Haemost
, vol.78
, pp. 656-660
-
-
Juhan-Vague, I.1
Alessi, M.C.2
-
63
-
-
19244384861
-
Enhanced thrombosis in atherosclerosis-prone mice is associated with increased arterial expression of plasminogen activator inhibitor-1
-
Schäfer K, Müller K, Hecke A, et al. Enhanced thrombosis in atherosclerosis-prone mice is associated with increased arterial expression of plasminogen activator inhibitor-1. Arterioscler Thromb Vasc Biol. 2003; 23: 2097-2103.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 2097-2103
-
-
Schäfer, K.1
Müller, K.2
Hecke, A.3
-
64
-
-
0035970097
-
Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice
-
Konstantinides S, Schäfer K, Thinnes T, Loskutoff DJ. Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice. Circulation. 2001; 103: 576-583.
-
(2001)
Circulation
, vol.103
, pp. 576-583
-
-
Konstantinides, S.1
Schäfer, K.2
Thinnes, T.3
Loskutoff, D.J.4
-
65
-
-
0035432902
-
Disruption of the plasminogen activator inhibitor 1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice
-
Schäfer K, Fujisawa K, Konstantinides S, Loskutoff DJ. Disruption of the plasminogen activator inhibitor 1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice. FASEB J. 2001; 15: 1840-1842.
-
(2001)
FASEB J
, vol.15
, pp. 1840-1842
-
-
Schäfer, K.1
Fujisawa, K.2
Konstantinides, S.3
Loskutoff, D.J.4
-
66
-
-
33845951873
-
Bone marrow plasminogen activator inhibitor-1 influences the development of obesity
-
De Taeye BM, Novitskaya T, Gleaves L, Covington JW, Vaughan DE. Bone marrow plasminogen activator inhibitor-1 influences the development of obesity. J Biol Chem. 2006; 281: 32796-32805.
-
(2006)
J Biol Chem
, vol.281
, pp. 32796-32805
-
-
de Taeye, B.M.1
Novitskaya, T.2
Gleaves, L.3
Covington, J.W.4
Vaughan, D.E.5
-
67
-
-
10744228409
-
Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1
-
Ma LJ, Mao SL, Taylor KL, et al. Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1. Diabetes. 2004; 53: 336-346.
-
(2004)
Diabetes
, vol.53
, pp. 336-346
-
-
Ma, L.J.1
Mao, S.L.2
Taylor, K.L.3
-
68
-
-
33749042156
-
Modulation of adipose tissue development by pharmacological inhibition of PAI-1
-
Crandall DL, Quinet EM, El Ayachi S, et al. Modulation of adipose tissue development by pharmacological inhibition of PAI-1. Arterioscler Thromb Vasc Biol. 2006; 26: 2209-2215.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 2209-2215
-
-
Crandall, D.L.1
Quinet, E.M.2
el Ayachi, S.3
-
69
-
-
62449221898
-
Effect of plasminogen activator inhibitor-1 on adipogenesis in vivo
-
Scroyen I, Jacobs F, Cosemans L, De Geest B, Lijnen HR. Effect of plasminogen activator inhibitor-1 on adipogenesis in vivo. Thromb Haemost. 2009; 101: 388-393.
-
(2009)
Thromb Haemost
, vol.101
, pp. 388-393
-
-
Scroyen, I.1
Jacobs, F.2
Cosemans, L.3
de Geest, B.4
Lijnen, H.R.5
-
70
-
-
0037234246
-
Nutritionally induced obesity is attenuated in transgenic mice overexpressing plasminogen activator inhibitor-1
-
Lijnen HR, Maquoi E, Morange P, et al. Nutritionally induced obesity is attenuated in transgenic mice overexpressing plasminogen activator inhibitor-1. Arterioscler Thromb Vasc Biol. 2003; 23: 78-84.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 78-84
-
-
Lijnen, H.R.1
Maquoi, E.2
Morange, P.3
-
71
-
-
0034071531
-
Influence of PAI-1 on adipose tissue growth and metabolic parameters in a murine model of diet-induced obesity
-
Morange PE, Lijnen HR, Alessi MC, Kopp F, Collen D, Juhan-Vague I. Influence of PAI-1 on adipose tissue growth and metabolic parameters in a murine model of diet-induced obesity. Arterioscler Thromb Vasc Biol. 2000; 20: 1150-1154.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1150-1154
-
-
Morange, P.E.1
Lijnen, H.R.2
Alessi, M.C.3
Kopp, F.4
Collen, D.5
Juhan-Vague, I.6
-
72
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes. Nature. 2001; 409: 307-312.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
-
73
-
-
0035815608
-
A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation
-
Kim KH, Lee K, Moon YS, Sul HS. A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation. J Biol Chem. 2001; 276: 11252-11256.
-
(2001)
J Biol Chem
, vol.276
, pp. 11252-11256
-
-
Kim, K.H.1
Lee, K.2
Moon, Y.S.3
Sul, H.S.4
-
74
-
-
0242320395
-
Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: Cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects
-
Lee JH, Chan JL, Yiannakouris N, et al. Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects. J Clin Endocrinol Metab. 2003; 88: 4848-4856.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4848-4856
-
-
Lee, J.H.1
Chan, J.L.2
Yiannakouris, N.3
-
75
-
-
29144432822
-
Resistin is secreted from macrophages in atheromas and promotes atherosclerosis
-
Jung HS, Park KH, Cho YM, et al. Resistin is secreted from macrophages in atheromas and promotes atherosclerosis. Cardiovasc Res. 2006; 69: 76-85.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 76-85
-
-
Jung, H.S.1
Park, K.H.2
Cho, Y.M.3
-
76
-
-
0032552988
-
Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor
-
Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun. 1998; 251: 471-476.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 471-476
-
-
Tatemoto, K.1
Hosoya, M.2
Habata, Y.3
-
77
-
-
20144380036
-
Apelin, a newly identified adipokine up-regulated by insulin and obesity
-
Boucher J, Masri B, Daviaud D, et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology. 2005; 146: 1764-1771.
-
(2005)
Endocrinology
, vol.146
, pp. 1764-1771
-
-
Boucher, J.1
Masri, B.2
Daviaud, D.3
-
78
-
-
70350572293
-
Effect of dietinduced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome
-
Heinonen MV, Laaksonen DE, Karhu T, et al. Effect of dietinduced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome. Nutr Metab Cardiovasc Dis. 2009; 19: 626-633.
-
(2009)
Nutr Metab Cardiovasc Dis
, vol.19
, pp. 626-633
-
-
Heinonen, M.V.1
Laaksonen, D.E.2
Karhu, T.3
-
79
-
-
55849094397
-
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
-
Chun HJ, Ali ZA, Kojima Y, et al. Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest. 2008; 118: 3343-3354.
-
(2008)
J Clin Invest
, vol.118
, pp. 3343-3354
-
-
Chun, H.J.1
Ali, Z.A.2
Kojima, Y.3
-
80
-
-
36348960661
-
Requirement of apelin- apelin receptor system for oxidative stress-linked atherosclerosis
-
Hashimoto T, Kihara M, Imai N, et al. Requirement of apelin- apelin receptor system for oxidative stress-linked atherosclerosis. Am J Pathol. 2007; 171: 1705-1712.
-
(2007)
Am J Pathol
, vol.171
, pp. 1705-1712
-
-
Hashimoto, T.1
Kihara, M.2
Imai, N.3
-
81
-
-
12344312427
-
Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells
-
Kleinz MJ, Skepper JN, Davenport AP. Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells. Regul Pept. 2005; 126: 233-240.
-
(2005)
Regul Pept
, vol.126
, pp. 233-240
-
-
Kleinz, M.J.1
Skepper, J.N.2
Davenport, A.P.3
-
82
-
-
33745048094
-
Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells
-
Hashimoto T, Kihara M, Ishida J, et al. Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2006; 26: 1267-1272.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1267-1272
-
-
Hashimoto, T.1
Kihara, M.2
Ishida, J.3
-
83
-
-
67650251902
-
Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats
-
Zhang Q, Yao F, Raizada MK, O'Rourke ST, Sun C. Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats. Circ Res. 2009; 104: 1421-1428.
-
(2009)
Circ Res
, vol.104
, pp. 1421-1428
-
-
Zhang, Q.1
Yao, F.2
Raizada, M.K.3
O'Rourke, S.T.4
Sun, C.5
-
84
-
-
2942711581
-
Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin- type 1 receptor in blood pressure in vivo
-
Ishida J, Hashimoto T, Hashimoto Y, et al. Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin- type 1 receptor in blood pressure in vivo. J Biol Chem. 2004; 279: 26274-26279.
-
(2004)
J Biol Chem
, vol.279
, pp. 26274-26279
-
-
Ishida, J.1
Hashimoto, T.2
Hashimoto, Y.3
-
85
-
-
50949099615
-
Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis
-
Eyries M, Siegfried G, Ciumas M, et al. Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis. Circ Res. 2008; 103: 432-440.
-
(2008)
Circ Res
, vol.103
, pp. 432-440
-
-
Eyries, M.1
Siegfried, G.2
Ciumas, M.3
|