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Volumn 2, Issue 8, 2011, Pages 794-799

Structure-based design, synthesis, and profiling of a β-tryptase inhibitor with a spiro-piperidineamide scaffold, benzylamine P1 group, and a substituted indole P4 group

(9) Liang, Guyan a Choi Sledeski, Yong Mi a Poli, Gregory B a Chen, Xin a Minnich, Anne a Wang, Qingping a Tsay, Joseph a Sides, Keith a Vaz, Roy J a

a SANOFI (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); BENZYLAMINE; BETA TRYPTASE; BETA TRYPTASE INHIBITOR; INDOLE; PIPERIDINE DERIVATIVE; POTASSIUM CHANNEL HERG; SEMICARBAZIDE SENSITIVIE AMINE OXIDASE; SPIROPIPERIDINEAMIDE; TRYPTASE; TRYPTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL;

EID: 79961149912 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c1md00104c Document Type: Article

Times cited : (8)

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