Renal effects of prolonged high protein intake and COX2 inhibition on hypertensive rats with altered renal development

American Journal of Physiology - Renal Physiology

Volumn 301, Issue 2, 2011, Pages

  Reverte, Virginia ^a,b   Tapia, Antonio ^a   Moreno, Juan Manuel ^a   Rodríguez, Leocadio ^c   Salazar, Francisco ^a   Teresa Llinas M ^a,b   Javier Salazar, F ^a,b  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

^c HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

Author keywords

Hypertension; Proteinuria; Renal function

Indexed keywords

ANGIOTENSIN II ANTAGONIST; CYCLOOXYGENASE 2 INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; FEMALE; GLOMERULUS FILTRATION RATE; HEMODYNAMICS; HYPERTENSION; KIDNEY DEVELOPMENT; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTAKE; RAT; SPRAGUE DAWLEY RAT; VASOCONSTRICTION;

EID: 79961147572     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00110.2011     Document Type: Article

References (31)

1. Abbate M, Zoja C, Remuzzi G. How does proteinuria cause progressive renal damage?. J Am Soc Nephrol 17: 2974-2984, 2006.
2. Alexander BT. Fetal programming of hypertension. Am J Physiol Regul Integr Comp Physiol 290: R1-R10, 2006.
3. Cattran DC, Reich HN, Beanlands HJ, Miller JA, Scholey JW, Troyanov S. The impact of sex in primary glomerulonephritis. Nephrol Dial Transplant 23: 2247-2253, 2008.
4. Chamorro-Jorganes A, Grande MT, Herranz B, Jerkic M, Griera M, Gonzalez-Nuñez M, Santos E, Rodríguez-Puyol D, Lopez-Novoa JM, Rodríguez-Puyol M. Targeted genomic disruption of H-Ras induces hypotension through a NO-cGMP-PKG pathway-dependent mechanism. Hypertension 56: 484-489, 2010.
5. Chung HY, Kim HJ, Shim KH, Kim KW. Dietary modulation of prostanoids synthesis in the aging process: role of cyclooxygenase-2. Mech Ageing Dev 111: 97-106, 1999.
6. Friedman AN. High-protein diets: potential effects on the kidney in renal health and disease. Am J Kidney Dis 44, 950-962, 2004.
7. Fujihara CK, Antunes GR, Mattar AL, Andreoli N, Malheiros DM, Noronha IL, Zatz R. Cyclooxigenase-2 (COX-2) inhibition limits abnormal COX-2 expression and progressive injury in the remnant kidney. Kidney Int 64: 2172-2181, 2003.
8. Gilbert JS, Nijland MJ. Sex differences in the developmental origins of hypertension and cardiorenal disease. Am J Physiol Regul Integr Comp Physiol 295: R1941-R1952, 2008.
9. Green T, Rodriguez J, Navar LG. Augmented cyclooxygenase-2 effects on renal function during varying states of angiotensin II. Am J Physiol Renal Physiol 299: F954-F962, 2010.
10. Keller G, Zimmer G, Mall G, Ritz E, Amann K. Nephron number in patients with primary hypertension. N Engl J Med 348: 101-108, 2003.
11. Loria A, Reverte V, Salazar F, Sáez F, Llinás MT, Salazar FJ. Sex and age differences of renal function in rats with reduced ANG II activity during the nephrogenic period. Am J Physiol Renal Physiol 293: F506-F510, 2007.
12. Loria A, Reverte V, Salazar F, Sáez F, Llinás MT, Salazar FJ. Changes in renal hemodynamics and excretory function induced by a reduction of ANG II effects during renal development. Am J Physiol Regul Integr Comp Physiol 293: R695-R700, 2007.
13. Machado FG, Poppi EP, Fanelli C, Malheiros DM, Zatz R, Fujihara CK. AT1 blockade during lactation as a model of chronic nephropathy: mechanisms of renal injury. Am J Physiol Renal Physiol 294: F1345-F1353, 2008.
14. Madsen K, Marcussen N, Pedersen M, Kjaersgaard G, Facemire C, Coffman TM, Jensen B. Angiotensin II promotes development of the renal microcirculation through AT1 receptors. J Am Soc Nephrol 21: 448-459, 2010.
15. Morigi M, Macconi D, Zoja C, Donadelli R, Buelli S, Zanchi C, Ghilardy M, Remuzz G. Protein overload induced NF-kappaB activation in proximal tubular cells requires H2O2 through a PKC-dependent pathway. J Am Soc Nephrol 13: 1179-1189, 2002.
16. Patterson ME, Mullins JJ, Mitchell KD. Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension. Am J Physiol Renal Physiol 294: F205-F211, 2008.
17. Pelayo JC, Shanley PF. Glomerular and tubular adaptive responses to acute nephron loss in the rat. Effect of prostaglandin synthesis inhibition. J Clin Invest 85: 1761-1769, 1990.
18. Pelayo JC, Wescott JY. Impaired autoregulation of glomerular capillary hydrostatic pressure in the rat remnant nephron. J Clin Invest 88: 101-105, 1991.
19. Potier M, Karl M, Zheng F, Elliot SJ, Striker GE, Striker LJ. Estrogen-related abnormalities in glomerulosclerosis-prone mice: reduced mesangial cell estrogen receptor expression and prosclerotic response to estrogens. Am J Pathol 160: 1877-1885, 2002.
20. Remuzzi G, Ruggenenti P, Benigni A. Understanding the nature of renal disease progression. Kidney Int 51: 2-15, 1997.
21. Saez F, Castells MT, Zuasti A, Salazar F, Reverte V, Loria A, Salazar FJ. Sex differences in the renal changes elicited by Ang II blockade during the nephrogenic period. Hypertension 49: 1429-1435, 2007.
22. Saez F, Reverte V, Salazar F, Castells MT, Llinas MT, Salazar FJ. Hypertension and sex differences in the age-related renal changes when cyclooxygenase-2 activity is reduced during nephrogenesis. Hypertension 53: 331-337, 2009.
23. Sakemi T, Toyoshima H, Morito F. Testosterone eliminates the attenuating effect of castration on the progressive glomerular injury in hyper-cholesterolemic male Imai rats. Nephron 67: 469-476, 1994.
24. Salazar F, Reverte V, Saez F, Loria A, Llinas MT, Salazar FJ. Age-and sodium-sensitive hypertension and sex-dependent renal changes in rats with a reduced nephron number. Hypertension 51: 1184-1189, 2008.
25. Szabo AJ, Wagner L, Elderly A, Lau K, Baylis C. Renal neuronal nitric oxide synthase protein expression as a marker of renal injury. Kidney Int 64: 1765-1771, 2003.
26. Tang L, Bi J, Valego N, Carey L, Figueroa J, Chappell M, Rose J. Prenatal betamethasone exposure alters renal function in immature sheep: sex-differences in effects. Am J Physiol Regul Integr Comp Physiol 299: R793-R803, 2010.
27. Wang JL, Cheng HF, Shappell S, Harris RC. A selective cyclooxygen-ase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats. Kidney Int 57: 2334-2342, 2000.
28. Wang JL, Cheng HF, Zhang MZ, McKanna JA, Harris RC. Selective increase of cyclooxygenase-2 expression in a model of renal ablation. Am J Physiol Renal Physiol 275: F613-F622, 1998.
29. Yang T, Huang YG, Ye W, Hansen P, Schnermann JB, Briggs JP. Influence of genetic background and gender on hypertension and renal failure in COX-2-deficient mice. Am J Physiol Renal Physiol 288: F1125-F1132, 2005.
30. Yao B, JIe X, Qi Z, Harris RC, Zhang MZ. Role of renal cortical cyclooxygenase-2 expression in hyperfiltration in rats with high-protein intake. Am J Physiol Renal Physiol 291: F368-F374, 2006.
31. Zandi-Nejad K, Luyckx VA, Brenner BM. Adult hypertension and kidney disease: the role of fetal programming. Hypertension 47: 502-508, 2006.