Selective increase of cyclooxygenase-2 expression in a model of renal ablation

American Journal of Physiology - Renal Physiology

Volumn 275, Issue 4 44-4, 1998, Pages

  Wang, Jun Ling ^a,b   Cheng, Hui Fang ^a,b   Zhang, Ming Zhi ^a,b   McKanna, James A ^a,b   Harris, Raymond C ^a,b  

^a Division of Nephrology   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cortical thick ascending limb of Henle's loop; Macula densa; Mesangial cell; Prostaglandin G H synthase; Renal failure

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; PROSTAGLANDIN SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; HENLE LOOP; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY FAILURE; MACULA DENSA; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT;

EID: 0031722956     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1998.275.4.f613     Document Type: Article

References (70)

1. Akai, Y., T. Homma, K. Burns, and R. C. Harris. Mechanical stretch/relaxation activates protooncogene expression in cultured rat glomerular mesangial cells by a protein kinase C-dependent mechanism. Am. J. Physiol. 267 (Cell Physiol. 36): C482-C490, 1994.
2. Anderson, S., T. W. Meyer, H. G. Rennke, and B. M. Brenner. Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass. J. Clin. Invest. 76: 612-619, 1985.
3. Bonvalet, J. P., P. Pradelles, and N. Farman. Segmental synthesis and actions of prostaglandins along the nephron. Am. J. Physiol. 253 (Renal Fluid Electrolyte Physiol. 22): F377-F387, 1987.
4. Breyer, R. M., L. S. Davis, C. Nian, R. Redha, B. Stillman, H. R. Jacobson, and M. D. Breyer. Cloning and expression of the rabbit prostaglandin EP4 receptor. Am. J. Physiol. 270 (Renal Fluid Electrolyte Physiol. 39): F485-F493, 1996.
5. Cheng, H. F., J. L. Wang, G. P. Vison, and R. C. Harris. Young spontaneous hypertensive rats (SHR) express increased type I angiotensin II receptors (AT1R) in renal proximal tubule. Am. J. Physiol. 274 (Renal Physiol. 43): F10-F17, 1998.
6. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
7. Conary, J., R. Parker, B. Christman, R. Faulks, G. King, B. Meryick, and K. Brigham. Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene. J. Clin. Invest. 93: 1834-1840, 1994.
8. Correa-Rotter, R., T. H. Hostetter, J. C. Manivel, and M. E. Rosenberg. Renin expression in renal ablation. Hypertension 20: 483-490, 1992.
9. DeWitt, D. L., and W. L. Smith. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc. Natl. Acad. Sci. USA 85: 1412-1416, 1988.
10. Dinchuk, J. E., B. D. Car, R. J. Focht, J. J. Johnston, B. D. Jaffee, M. B. Covington, N. R. Contel, V. M. Eng, R. J. Colins, P. M. Czerniak, S. A. Gorry, and J. M. Trzaskos. Renal abnormalities and altered inflammatory response in mice lacking cyclooxygenase II. Nature 378: 406-409, 1995.
11. Don, B. R., S. Blake, F. N. Hutchison, G. A. Kayson, and M. Schambelan. Dietary protein intake modulates glomerular eicosanoid production in the rat. Am. J. Physiol. 256 (Renal Fluid Electrolyte Physiol. 25): F711-F718, 1989.
12. DuBois, R. N, M. Tsujii, P. Bishop, J. A. Awad, K. Makita, and A. Lanahan. Cloning and characterization of a growth factor inducible cyclooxygenase gene from rat intestinal epithelial cells. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G822-G827, 1994.
13. Dunn, M. J., and V. L. Hood. Prostaglandins and the kidney. Am. J. Physiol. 233 (Renal Fluid Electrolyte Physiol. 2): F169-F184, 1977.
14. Feng, L., W. Sun, Y. Xia, W. W. Tang, P. Chanmugam, E. Soyoola, C. B. Wilson, and D. Hwang. Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression. Arch. Biochem. Biophys. 307: 361-368, 1993.
15. Fletcher, B. S., D. A. Kujubu, D. M. Perrin, and H. R. Herschman. Structure of the mitogen-inducible TIS 10 gene and demonstration that the TIS 10-encoded protein is a functional prostaglandin G/H synthase J. Biol. Chem. 267: 4338-4344, 1992.
16. Goldring, M. B., and S. M. Krane. Modulation by recombinant interleukin I of synthesis of types I and III collagens and associated procollagen mRNA levels in cultured human cells. J. Biol. Chem. 262: 16724-16729, 1987.
17. Goldstein, R. H., and P. Polgar. The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts. J. Biol. Chem. 257: 8630-8633, 1982.
18. Griffin, K. A., A. K. Bidani, M. Picken, V. R. Ellis, and P. C. Churchill. Prostaglandins do not mediate impaired autoregulation or increased renin secretion in remnant rat kidneys. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F1057-F1062, 1992.
19. 4 release from activated neutrophils. Proc. Natl. Acad. Sci. USA 80: 4349-4353, 1983.
20. Harding, P, D. H. Sigmon, M. E. Alfie, P. L. Huang, M. C. Fishman, W. H. Beierwaltes, and O. A. Carretero. Cyclooxygenase-2 mediates increased renal renin content induced by low-sodium diet. Hypertension 29: 297-302, 1997.
21. Harris, R. C. The macula densa: recent developments. J. Hypertens. 14: 815-822, 1996.
22. Harris, R. C., J. A. McKanna, Y. Akai, H. R. Jacobson, R. N. Dubois, and M. D. Breyer. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J. Clin. Invest. 94: 2504-2510, 1994.
23. Homma, T., R. L. Hoover, and R. C. Harris. Loop diuretic-sensitive potassium flux pathways of rat glomerular mesangial cells. Am. J. Physiol. 258 (Cell Physiol. 27): C862-C870, 1990.
24. Kelefiotis, D., B. A. Bresnahan, I. Stratidakis, and E. A. Lianos. Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. Prostaglandins 49: 269-283, 1995.
25. Klahr, S., and M. L. Pukerson. The pathophysiology of obstructive nephropathy: the role of vasoactive compounds in the hemodynamic and structural abnormalities of the obstructed kidney. Am. J. Kidney Dis. 23: 219-223, 1994.
26. Kömhoff, M., H. J. Grone, T. Klein, H. W. Seyberth, and R. M. Nusing. Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: implication for renal function. Am. J. Physiol. 272 (Renal Physiol. 41): F460-F468, 1997.
27. Kujubu, D. A., B. S. Fletcher, B. C. Varnum, R. W. Lim, and H. R. Herschman. TIS 10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J. Biol. Chem. 266: 12866-12872, 1991.
28. Laneuville, O., D. K. Breuer, D. L. Dewitt, T. Hla, C. D. Funk, and W. L. Smith. Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. J. Pharmacol. Exp. Ther. 271: 927-934, 1994.
29. Langenbach, R., S. G. Morham, H. F. Tiano, C. D. Loftin, B. Ghanayem, P. Chulada, J. Mahler, C. Lee, E. Goulding, K. Kluckrnan, H. S. Kim, and O. Smithies. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 83: 483-492, 1995.
30. Logan, J. L., S. M. Lee, B. Benson, and U. F. Michael. Inhibition of compensatory renal growth by indomethacin. Prostaglandins 31: 253-261, 1986.
31. 2 and hyaluronan on mesangial cell proliferation. A potential contribution to glomerular hypercellularity in diabetes. Diabetes 45: 44-50, 1996.
32. Masferrer, J. L., K. Seibert, B. Zweifel, and P. Needleman. Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme. Proc. Natl. Acad. Sci. USA 89: 3917-3921, 1992.
33. Matsell, D. G., L. W. Gaber, and K. U. Malik. Cytokine stimulation of prostaglandin production inhibits the proliferation of serum-stimulated mesangial cells. Kidney Int. 45: 159-165, 1994.
34. Meade, E. A., W. L. Smith., and D. L. DeWitt. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. J. Biol. Chem. 268: 6610-6614, 1993.
35. Mitchell, J. A., P. Akarasereenont, C. Thiemermann, R. J. Flower, and J. R. Vane. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. USA 90: 11693-11697, 1993.
36. Morham, S. G., R. Langenbach., C. D. Loftin, H. F. Tiano, N. Vouloumanos, J. C. Jennette, J. F. Mahler, K. D. Kluckrnan, A. Ledford, C. A. Lee, E. H. Goulding, K. D. Kluckman, H. S. Kim, and O. Smithies. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 83: 473-472, 1995.
37. Murray, B. M., and G. P. Brown. Effect of protein intake on the autoregulation of renal blood flow. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F168-F174, 1990.
38. Nakahama, K., I. Morita, and S. Murota. Effects of endogenously produced arachidonic acid metabolites on rat mesangial cell proliferation. Prostaglandins Leukot. Essent. Fatty Acids 51: 177-182, 1994.
39. Nath, K. A., D. H. Chmielewski, and T. H. Hostetter. Regulatory role of prostanoids in glomerular microcirculation of remnant nephrons. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F829-F837, 1987.
40. Negrete, H., R. K. Studer, P. A. Craven, and F. R. DeRubertis. Role for transforming growth factor beta in thromboxane-induced increases in mesangial cell fibronectin synthesis. Diabetes 44: 335-339, 1995.
41. O'Banion, M. K., V. D. Winn, and D. A. Young. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA 89: 4888-4892, 1992.
42. O'Banion, M. K., H. B. Sadowski, V. Winn, and D. A. Young. A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein J. Biol. Chem. 266: 23261-23267, 1991.
43. O'Neill, G. P., and A. W. Ford-Hutchinson. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett. 330: 156-160, 1993.
44. 2. J. Immunol. 152: 5703-5713, 1994.
45. Pelayo, J. C., and P. F. Shanley. Glomerular and tubular adaptive responses to acute nephron loss in the rat. Effect of prostaglandin synthesis inhibition. J. Clin. Invest. 85: 1761-1769, 1990.
46. Pelayo, J. C., and J. Y. Westcott. Impaired autoregulation of glomerular capillary hydrostatic pressure in the rat remnant nephron. J. Clin. Invest. 88: 101-105, 1991.
47. Pelayo, J. C., A. H. Quan, and P. F. Shanley. Angiotensin II control of the renal microcirculation in rats with reduced renal mass. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F414-F422, 1990.
48. Pupilli, C., R. L. Chevalier, R. M. Carey, and R. A. Gomez. Distribution and content of renin and renin mRNA in remnant kidney of adult rat. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F731-F738, 1992.
49. Purkerson, M. L., J. H. Joist, J. Yates, A. Valdes, A. Morrison, and S. Klahr. Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. Proc. Natl. Acad. Sci. USA 82: 193-197, 1985.
50. Reddy, S. T., and H. R. Herschman. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGHS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J. Biol. Chem. 269: 15473-15480, 1994.
51. Remuzzi, G., G. A. FitzGerald, and C. Patrono. Thromboxane synthesis and action within the kidney. Kidney Int. 41: 1483-1493, 1992.
52. Rosenberg, M. E., L. J. Smith, R. Correa-Rotter, and T. H. Hostetter. The paradox of the renin-angiotensin system in chronic renal disease. Kidney Int. 45: 403-410, 1994.
53. Rosenherg, M. E., R. Correa-Rotter, T. Inagami, S. M. Kren, and T. H. Hostetter. Glomerular renin synthesis and storage in the remnant kidney in the rat. Kidney Int. 40: 677-683, 1991.
54. Schmitz, P. G., S. M. Krupa, P. H Lane, J. C. Reddington, and L. Salinas-Madrigal. Acquired essential fatty acid depletion in the remnant kidney: amelioration with U-63557A. Kidney Int. 46: 1184-1191, 1994.
55. Singhal, P. C., S. Sagar, P. Garg, and V. Bansal. Vasoactive agents modulate matrix metalloproteinase-2 activity by mesangial cells. Am. J. Med. Sci. 310: 235-241, 1995.
56. Smith, W. L., and T. G. Bell. Immunohistochemical localization of the prostaglandin-forming cyclooxygenase in renal cortex. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F451-F457, 1978.
57. Stahl, R. A. K., S. Kudelka, and U. Helmchen. High protein intake stimulates glomerular prostaglandin formation in remnant kidneys. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F1083-F1094, 1987.
58. Stahl, R. A. K., S. Kudelka, M. Paravicini, and P. Schollmeyer. Prostaglandin and thromboxane formation in glomeruli from rats with reduced renal mass. Nephron 42: 252-257, 1986.
59. Stroebel, M., and M. Goppelt-Struebe. Signal transduction pathways responsible for serotonin-mediated prostaglandin G/H synthase expression in rat mesangial cells. J. Biol. Chem. 269: 22952-22957, 1994.
60. Studer, R. K., H. Negrete, P. A. Craven, and F. R. DeRubertis. Protein kinase C signals thromboxane induced increases in fibronectin synthesis and TGF-beta bioactivity in mesangial cells. Kidney Int. 48: 422-430, 1995.
61. 2 during late nephrotoxic serum glomerulonephritis in the rat. J. Clin. Invest. 85: 1974-1982, 1990.
62. Tippets, M. T., B. C. Varnum, R. W. Lim, and H. R. Herschman. Tumor promoter-inducible genes are differentially expressed in the developing mouse. Mol. Cell. Biol. 8: 4570-4572, 1988.
63. 2 causes a coordinate decrease in the steady state levels of fibronectin and types I and III procollagen mRNAs in normal human dermal fibroblasts. Biochem. Biophys. Res. Commun. 147: 1282-1288, 1987.
64. Villa, E., J. Martinez, L. M. Ruilope, F. Mampaso, J. M. Sancho, and R. G. Robles. Cicaprost, a prostacyclin analog, protects renal function in uninephrectomized dogs in the absence of changes in blood pressure. Am. J. Hypertens. 6: 253-257, 1993.
65. Vio, C. P., C. Cespedes, P. Gallardo, and J. L. Masferrer. Renal identification of cyclooxygenase-2 in a subset of thick ascending limb cells. Hypertension 30: 687-692, 1997.
66. 2 and to express cyclooxygenase-2. J. Clin. Invest. 95: 1861-1868, 1995.
67. Yanagisawa, H., J. Morrissey, and S. Klahr. Mechanism of enhanced eicosanoid production by isolated glomeruli from rats with bilateral ureteral obstruction. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F248-F255, 1991.
68. 2 on mRNA expression and secretion of collagens I, III, and IV and fibronectin in cultured rat mesangial cells. J. Am. Soc. Nephrol. 4: 1778-1785, 1994.
69. Zhang, M.-Z., J.-L. Wang, H.-F. Cheng, R. C. Harris, and J. A. McKanna. Cyclooxygenase-2 in rat nephron development. Am. J. Physiol. 273 (Renal Physiol. 42): F994-F1002, 1997.
70. Zoja, C., N. Perico, D. Corna, A. Benigni, M. Gabanelli, M. Morigi, T. Bertani, and G. Remuzzi. Thromboxane synthesis inhibition increases renal prostacyclin and prevents renal disease progression in rats with remnant kidney. J. Am. Soc. Nephrol. 1: 799-807, 1990.