A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats

Kidney International

Volumn 57, Issue 6, 2000, Pages 2334-2342

  Wang, Jun Ling ^a   Cheng, Hui Fang ^a   Shappell, Scott ^a   Harris, Raymond C ^a,b  

^a Division of Nephrology   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glomerulosclerosis; Macula densa; Renal failure; Tubulointerstitium

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; COLLAGEN TYPE 3; COLLAGEN TYPE 4; CYCLOOXYGENASE 2 INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DRUG VEHICLE; ENALAPRIL; MESSENGER RNA; METHYLCELLULOSE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SELECTIVITY; GLOMERULOSCLEROSIS; HYPERTENSION; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT;

EID: 0034128995     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00093.x     Document Type: Article

References (53)

1. 1. NEEDLEMAN P, TURK J, JAKSCHIK BA, MORRISON AR, LEFKOWITH JB: Arachidonic acid metabolism. Annu Rev Biochemistry 55:69-102, 1986
2. 2. BRFYER MD: Prostaglandin receptors in the kidney: A new route for intervention? Exp Nephrol 6:180-188, 1998
3. 3. DEWITT DL, SMITH WL: Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci USA 85:1412-1416, 1988
4. 4. SMITH WL, BELL TG: Immunohistochemical localization of the prostaglandin-forming cyclooxygenase in renal cortex. Am J Physiol 235:F451-F457, 1978
5. 5. HARRIS RC, MCKANNA JA, AKAI Y, JACOBSON HR, DUBOIS RN, BREYER MD: Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 94:2504-2510, 1994
6. 6. KUJUBU DA, FLETCHER BS, VARNUM BC, LIM RW, HERSCHMAN HR: TIS 10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/ cyclooxygenase homologue. J Biol Chem 266:12866-12872, 1991
7. 7. FLETCHER BS, KUJUBU DA, PERRIN DM, HERSCHMAN HR: Structure of the mitogen-inducible TIS 10 gene and demonstration that the TIS 10-encoded protein is a functional prostaglandin G/H synthase. J Biol Chem 267:4338-4344, 1992
8. 8. MASFERRER JL, REDDY ST, ZWEIFEL BS, SEIBERT K, NEEDLEMAN P, GILBERT RS, HERSCHMAN HR: In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages. J Pharmacol Exp Ther 270:1340-1344, 1994
9. 9. O'BANION MK, WINN VD, YOUNG DA: cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc Natl Acad Sci USA 89:4888-4892, 1992
10. 10. DUBOIS RN, ABRAMSON SB, CROFFORD L, GUPTA RA, SIMON LS, VAN DE PUTTE LB, LIPSKY PE: Cyclooxygenase in biology and disease. FASEB J 12:1063-1073, 1998
11. 11. JENSEN BL, KURTZ A: Differential regulation of renal cyclooxygenase mRNA by dietary salt intake. Kidney Int 52:1242-1249, 1997
12. 12. YANG T, SINGH I, PHAM H, SUN D, SMARI A, SCHNERMANN JB, BRIGGS JP: Regulation of cyclooxygenase expression in the kidney by dietary salt intake. Am J Physiol 274:F481-F489, 1998
13. 13. WANG J-L, CHENG H-F, ZHANG M-Z, MCKANNA JA, HARRIS RC: Selective increase of cyclooxygenase-2 expression in a model of renal ablation. Am J Physiol 275:F613-F622, 1998
14. 14. NATH KA, CHMIELEWSKI DH, HOSTETTER TH: Regulatory role of prostanoids in glomerular microcirculation of remnant nephrons. Am J Physiol 252:F829-F837, 1987
15. 15. PELAYO JC, SHANLEY PF: Glomerular and tubular adaptive responses to acute nephron loss in the rat: Effect of prostaglandin synthesis inhibition. J Clin Invest 85:1761-1769, 1990
16. 16. PURKERSON ML, JOIST JH, YATES J, VAIDES A, MORRISON A, KLAHR S: Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. Proc Natl Acad Sci USA 82:193-197, 1985
17. 17. SCHMITZ PG, KRUPA SM, LANE PH, REDDINGTON JC, SALINAS-MADRIGAI L: Acquired essential fatty acid depletion in the remnant kidney: Amelioration with U-63557A. Kidney Int 46:1184-1191, 1994
18. 18. STAHL RAK, KUDELKA S, HELMCHEN U: High protein intake stimulates glomerular prostaglandin formation in remnant kidneys. Am J Physiol 252:F1083-F1094, 1987
19. 19. STAHL RAK, KUDELKA S, PARAVICINI M, SCHOLLMEYER P: Prostaglandin and thromboxane formation in glomeruli from rats with reduced renal mass. Nephron 42:242-257, 1986
20. 20. PENNING TD, TALLEY JJ, BERTENSHAW SR, CARTER JS, COLLINS PW, DOCTER S, GRANETO MJ, LEE LF, MALECHA JW, MIYASHIRO JM, ROGERS RS, ROGIER DJ, YU SS, ANDERSONGD BURTON EG, COGBURN JN, GREGORY SA, KOBOLDT CM, PERKINS WE, SEIBERT K, VEENHUIZEN AW, ZHANG YY, ISAKSON PC: Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). J Med Chem 40:1347-1365, 1997
21. 21. ANDERSON S, MEYER TW, RENNKE HG, BRENNER BM: Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass. J Clin Invest 76:612-619, 1985
22. 22. CHENG HF, WANG JL, ZHANG MZ, MIYAZAKI Y, ICHIKAWA I, MCKANNA JA, HARRIS RC: Angiotensin II attenuates renal cortical cyclooxygenase-2 expression. J Clin Invest 103:953-961, 1999
23. 23. WANG JL, CHENG HF, HARRIS RC: Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. Hypertension 34:96-101, 1999
24. 24. FUJIHARA CK, MALHEIROS DM, DONATO JL, POLI A, DE NUCCI G, ZATZ. R: Nitroflurbiprofen, a new nonsteroidal anti-inflammatory, ameliorates structural injury in the remnant kidney. Am J Physiol 274:F573-F579, 1998
25. 25. DON BR, BLAKE S, HUTCHISON FN, KAYSON GA, SCHAMBELAN M: Dietary protein intake modulates glomerular eicosanoid production in the rat. Am J Physiol 252:F711-F718, 1989
26. 26. NAKAHAMA K, MORHA I, MUROTA S: Effects of endogenously produced arachidonic acid metabolites on rat mesangial cell proliferation. Prostaglandins Leukot Essent Fatty Acids 51:177-182, 1994
27. 27. MATSELL D, GABER L, MALIK KKI: Cytokine stimulation of prostaglandin production inhibits the proliferation of serum-stimulated mesangial cells. Kidney Int 45:159-165, 1994
28. 28. ZAHNER G, DISSER M, THAISS F, WOLF G, SCHOEPPE W, STAHL R: The effect of prostaglandin E2 on mRNA expression and secretion of collagens I III, and IV and fibronectin in cultured rat mesangial cells. J Am Soc Nephrol 4:1778-1785, 1994
29. 29. SINGHAL P, SAGAR S, GARG P, BANSAL V: Vasoactive agents modulate matrix metalloproteinase-2 activity by mesangial cells. Am J Med Sci 310:235-241, 1995
30. 30. KELETIOTIS D, BRESNAHAN B, STRATIDAKIS I, LIANOS EP: Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. Prostaglandins 49:269-283, 1995
31. 31. ZOJA, C, PERICO N, CORNA D, BENIGNI A, GABANELLI M, MORIGI M, BERTANI T, REMUZZI G: Thromboxane synthesis inhibition increases renal prostacyclin and prevents renal disease progression in rats with remnant kidney. J Am Soc Nephrol 1:799-807, 1990
32. 32. STAHL R, THAISS F, WENZEL U, SCHOEPPE W, HEIMCHEN U: A rat model of progressive chronic glomerular sclerosis: The role of thromboxane inhibition. J Am Soc Nephrol 2:1568-1577, 1992
33. 33. NEGRETE H, SIUDER R, CRAVEN P, DERUBERTIS F: Role for transforming growth factor beta in thromboxane-induced increases in mesangial cell fibronectin synthesis. Diabetes 44:335-339, 1995
34. 34. STUDER R, NEGRETE H, CRAVEN P, DERUBERTIS F: Protein kinase C signals thromboxane induced increases in fibronectin synthesis and TGF-beta bioactivity in mesangial cells. Kidney Int 48:422-430, 1995
35. 35. PUPILLI C, CHEVALIER RL, CAREY RM, GOMEZ RA: Distribution and content of renin and renin mRNA in remnant kidney of adult rat. Am J Physiol 263:F731-F738, 1992
36. 36. ROSENBERG ME, SMITH LJ, CORREA-ROTTER R, HOSTETTER TH: The paradox of the renin-angiotensin system in chronic renal disease. Kidney Int 45:403-410, 1994
37. 37. CORREA-ROTTER R, HOSTETTER TH, MANIVEL JC, ROSENBERG ME: Renin expression in renal ablation. Hypertension 20:483-490, 1992
38. 38. ROSENBERG ME, CORREA-ROTTER R, INAGAMI T, KREN SM, HOSTETTER TH: Glomerular renin synthesis and storage in the remnant kidney in the rat. Kidney Int 40:677-683, 1991
39. 39. BADR K: Arachidonic acid metabolites in glomerular immune injury. Semin Nephrol 11:332-339, 1991
40. 40. BERGSTEIN JM: Prostaglandin inhibitors in the treatment of nephrotic syndrome. Pediatr Nephrol 5:335-338, 1991
41. 41. DUNN MJ: Prostaglandins, angiotensin II, and proteinuria. Nephron 55:30-37, 1990
42. 42. VRIESENDORP R, DONKER AJ, DE ZEEUW D, DE JONG PE, VAN DER HEM GK, BRENTJENS JR: Effects of nonsteroidal anti-inflammatory drugs on proteinuria. Am J Med 81:84-94, 1986
43. 43. HEEG JE, DE JONG PE, VRIESENDORP R, DE ZFEUW D: Additive antiproteinuric effect of the NSAID indomethacin and the ACE inhibitor lisinopril. Am J Nephrol 10:94-97, 1990
44. 44. MURRAY BM, BROWN GP: Effect of protein intake on the autoregulation of renal blood flow. Am J Physiol 258:F168-F174, 1990
45. 45. PELAYO J, WESTCOTT J: Impaired autoregulation of glomerular capillary hydrostatic pressure in the rat remnant nephron. J Clin Invest 88:101-105, 1991
46. 46. WILKE WL, PERSSON AE: Captopril and tubuloglomerular feedback in remnant kidneys of prehypertensive rats. J Am Soc Nephrol 3:73-79, 1992
47. 47. SENEY FD JR. WRIGHT FS: Dietary protein suppresses feedback control of glomerular filtration in rats. J Clin Invest 75:558-568, 1985
48. 48. SENEY FD JR, PERSSON EG, WRIGHT FS: Modification of tubuloglomerular feedback signal by dietary protein. Am J Physiol 252:F83-F90, 1987
49. 49. HAHNE B, SELEN G, ERIK A, PERSSON G: Indomethacin inhibits renal functional adaptation to nephron loss. Renal Physiol 7:13-21, 1984
50. 50. WILCOX CS, WELCH WJ, MURAD F, GROSS SS, TAYLOR G, LEVI R, SCHMIDT HH: Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci USA 89:11993-11997, 1992
51. 51. WELCH WJ, WILCOX CS: Role of nitric oxide in tubuloglomerular feedback: Effects of dietary salt. Clin Exp Pharmacol Physiol 24:582-586, 1997
52. 52. THORUP C, ERIK A, PERSSON G: Macula densa derived nitric oxide in regulation of glomerular capillary pressure. Kidney Int 49:430-436, 1996
53. 53. ICHIHARA A, IMIG JD, INSCHO EW, NAVAR LG: Cyclooxygenase-2 participates in tubular flow-dependent afferent arteriolar tone: Interaction with neuronal NOS. Am J Physiol 275:F605-F612, 1998