메뉴 건너뛰기




Volumn 76, Issue 9, 2011, Pages

Survival, Acid and Bile Tolerance, and Surface Hydrophobicity of Microencapsulated B. animalis ssp. lactis Bb12 during Storage at Room Temperature

Author keywords

Alginate based microencapsulation; Bifidobacteria; Long term storage; Low a w; Probiotic

Indexed keywords

ALGINIC ACID; MANNITOL; PROBIOTIC AGENT;

EID: 79961128260     PISSN: 00221147     EISSN: 17503841     Source Type: Journal    
DOI: 10.1111/j.1750-3841.2011.02422.x     Document Type: Article
Times cited : (37)

References (55)
  • 1
    • 34247613159 scopus 로고    scopus 로고
    • Recent advances in microencapsulation of probiotics for industrial applications and targeted delivery: a review
    • Anal AK, Singh H. 2007. Recent advances in microencapsulation of probiotics for industrial applications and targeted delivery: a review. Trends Food Sci Technol 18:240-51.
    • (2007) Trends Food Sci Technol , vol.18 , pp. 240-251
    • Anal, A.K.1    Singh, H.2
  • 2
    • 0001872327 scopus 로고    scopus 로고
    • Bifidobacteria and probiotic action
    • In: Salminen S and Wright AV, editors. 2nd ed. New York: Marcel Dekker. (617 p)
    • Ballongue J. 1998. Bifidobacteria and probiotic action. In: Salminen S and Wright AV, editors. Lactic acid bacteria: microbiology and functional aspects. 2nd ed. New York: Marcel Dekker. p. 519-587 (617 p).
    • (1998) Lactic acid bacteria: microbiology and functional aspects , pp. 519-587
    • Ballongue, J.1
  • 3
    • 33845262198 scopus 로고    scopus 로고
    • Understanding lyophilization formulation development
    • Available from
    • Bedu-Addo FK. 2004. Understanding lyophilization formulation development. Pharm Technol (Lyophilization):10-8. Available from
    • (2004) Pharm Technol (Lyophilization):10-8
    • Bedu-Addo, F.K.1
  • 4
    • 0032665707 scopus 로고    scopus 로고
    • Implication of glass transition for the drying and stability of dried foods
    • Bhandari BR, Howes T. 1999. Implication of glass transition for the drying and stability of dried foods. J Food Eng 40:71-9.
    • (1999) J Food Eng , vol.40 , pp. 71-79
    • Bhandari, B.R.1    Howes, T.2
  • 6
    • 0003954817 scopus 로고
    • 2nd ed. New York: McGraw-Hill.
    • Carey FA. 1992. Organic chemistry 2nd ed. New York: McGraw-Hill. 1272 p.
    • (1992) Organic chemistry , pp. 1272
    • Carey, F.A.1
  • 7
    • 0026493277 scopus 로고
    • Interaction of stabilizing additives with proteins during freeze-thawing and freeze-drying
    • Carpenter JF, Arakawa T, Crowe JH. 1991. Interaction of stabilizing additives with proteins during freeze-thawing and freeze-drying. Dev Biol Stand 74:225-39.
    • (1991) Dev Biol Stand , vol.74 , pp. 225-239
    • Carpenter, J.F.1    Arakawa, T.2    Crowe, J.H.3
  • 8
    • 4143146616 scopus 로고    scopus 로고
    • Relevant factors for the preparation of freeze-dried lactic acid bacteria-review
    • Carvalho AS, Silva J, Ho P, Teixeira P, Malcata FX, Gibbs P. 2004. Relevant factors for the preparation of freeze-dried lactic acid bacteria-review. Int Dairy J 14:835-47.
    • (2004) Int Dairy J , vol.14 , pp. 835-847
    • Carvalho, A.S.1    Silva, J.2    Ho, P.3    Teixeira, P.4    Malcata, F.X.5    Gibbs, P.6
  • 9
    • 0031793406 scopus 로고    scopus 로고
    • Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized Anti-IgE monoclonal antibody
    • Constantino HR, Andya JD, Nguyen PA, Dasovich N, Sweeney TD, Shire SJ, Hsu CC, Maa YF. 1998. Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized Anti-IgE monoclonal antibody. J Pharm Sci 87(11):1406-11.
    • (1998) J Pharm Sci , vol.87 , Issue.11 , pp. 1406-1411
    • Constantino, H.R.1    Andya, J.D.2    Nguyen, P.A.3    Dasovich, N.4    Sweeney, T.D.5    Shire, S.J.6    Hsu, C.C.7    Maa, Y.F.8
  • 10
    • 80052440754 scopus 로고    scopus 로고
    • The resistance to freeze-drying and to storage was determined as the cellular ability to recover its survival rate and acidification activity
    • DOI
    • Coulibaly I, Dubois-Dauphin R, Destain J, Fauconnier ML, Lognay G, Thonart P. 2010. The resistance to freeze-drying and to storage was determined as the cellular ability to recover its survival rate and acidification activity. Int J Microbiol 2010:625239. DOI
    • (2010) Int J Microbiol , vol.2010 , pp. 625239
    • Coulibaly, I.1    Dubois-Dauphin, R.2    Destain, J.3    Fauconnier, M.L.4    Lognay, G.5    Thonart, P.6
  • 11
    • 0002469071 scopus 로고
    • Preserving dry biomaterials: the water replacement hypothesis, part 1
    • Crowe JH, Crowe LM, Carpenter JF. 1993. Preserving dry biomaterials: the water replacement hypothesis, part 1. Biopharm 6(3):28-32.
    • (1993) Biopharm , vol.6 , Issue.3 , pp. 28-32
    • Crowe, J.H.1    Crowe, L.M.2    Carpenter, J.F.3
  • 12
    • 33748371655 scopus 로고    scopus 로고
    • Effect of additives on the viability of bifidobacteria loaded in alginate poly-l-lysine microparticles during the freeze-drying process
    • Cui J-H, Cao Q-R, Choi Y-J, Lee K-H, Lee B-J. 2006. Effect of additives on the viability of bifidobacteria loaded in alginate poly-l-lysine microparticles during the freeze-drying process. Arch Pharm Res 29(8):707-11.
    • (2006) Arch Pharm Res , vol.29 , Issue.8 , pp. 707-711
    • Cui, J.-H.1    Cao, Q.-R.2    Choi, Y.-J.3    Lee, K.-H.4    Lee, B.-J.5
  • 15
    • 57649211653 scopus 로고    scopus 로고
    • Microencapsulation of Lactobacillus plantarum spp in an alginate matrix coated with whey proteins
    • Gbassi GK, Vandamme T, Ennahar S, Marchioni E. 2009. Microencapsulation of Lactobacillus plantarum spp in an alginate matrix coated with whey proteins. Int J Food Microbiol 129:103-5.
    • (2009) Int J Food Microbiol , vol.129 , pp. 103-105
    • Gbassi, G.K.1    Vandamme, T.2    Ennahar, S.3    Marchioni, E.4
  • 16
    • 2342630757 scopus 로고    scopus 로고
    • Microencapsulation-industrial appraisal of existing technologies and trend
    • Gouin S. 2004. Microencapsulation-industrial appraisal of existing technologies and trend. Trends Food Sci Technol 15:330-47.
    • (2004) Trends Food Sci Technol , vol.15 , pp. 330-347
    • Gouin, S.1
  • 17
    • 76549088749 scopus 로고    scopus 로고
    • Influence of casein-based microencapsulation on freeze-drying and storage of probiotic cells
    • Heidebach T, Forst P, Kulozik U. 2010. Influence of casein-based microencapsulation on freeze-drying and storage of probiotic cells. J Food Eng 98:309-16.
    • (2010) J Food Eng , vol.98 , pp. 309-316
    • Heidebach, T.1    Forst, P.2    Kulozik, U.3
  • 18
    • 34547893471 scopus 로고    scopus 로고
    • Impact of water activity, temperature, and physical state on the storage stability of Lactobacillus paracasei ssp. paracasei freeze-dried in a lactose matrix
    • Higl B, Kurtmann L, Carlsen CU, Ratjen J, Forst P, Skibsted LH, Kulozik U, Risbo J. 2007. Impact of water activity, temperature, and physical state on the storage stability of Lactobacillus paracasei ssp. paracasei freeze-dried in a lactose matrix. Biotechnol Prog 23:794-800.
    • (2007) Biotechnol Prog , vol.23 , pp. 794-800
    • Higl, B.1    Kurtmann, L.2    Carlsen, C.U.3    Ratjen, J.4    Forst, P.5    Skibsted, L.H.6    Kulozik, U.7    Risbo, J.8
  • 19
    • 1242315604 scopus 로고    scopus 로고
    • In vitro assessment of the upper gastrointestinal tolerance of potential probiotic dairy propionibacteria
    • Huang Y, Adams MC. 2004. In vitro assessment of the upper gastrointestinal tolerance of potential probiotic dairy propionibacteria. Int J Food Microbiol 91:253-60.
    • (2004) Int J Food Microbiol , vol.91 , pp. 253-260
    • Huang, Y.1    Adams, M.C.2
  • 20
    • 0035994868 scopus 로고    scopus 로고
    • Excipient crystallinity and its protein-structurestabilizing effect during freeze-drying
    • Izutsu K, Kojima S. 2002. Excipient crystallinity and its protein-structurestabilizing effect during freeze-drying. J Pharm Pharmacol 54:1033-9.
    • (2002) J Pharm Pharmacol , vol.54 , pp. 1033-1039
    • Izutsu, K.1    Kojima, S.2
  • 21
    • 1542328823 scopus 로고    scopus 로고
    • Effects of sodium tetraborate and boric acid on nonisothermal mannitol crystallization in frozen solutions and freeze-dried solids
    • Izutsu K, Ocheda SO, Aoyagi N, Kojima S. 2004. Effects of sodium tetraborate and boric acid on nonisothermal mannitol crystallization in frozen solutions and freeze-dried solids. Int J Pharm 273:85-93.
    • (2004) Int J Pharm , vol.273 , pp. 85-93
    • Izutsu, K.1    Ocheda, S.O.2    Aoyagi, N.3    Kojima, S.4
  • 22
    • 33745435175 scopus 로고    scopus 로고
    • Survival of free and encapsulated probiotic bacteria and their effect on the sensory properties of yoghurt
    • Kailasapathy K. 2006. Survival of free and encapsulated probiotic bacteria and their effect on the sensory properties of yoghurt. Lebensm Wiss Technol 39:1221-7.
    • (2006) Lebensm Wiss Technol , vol.39 , pp. 1221-1227
    • Kailasapathy, K.1
  • 24
    • 0000880579 scopus 로고    scopus 로고
    • Effect of rehydration media and immobilization in Ca-alginate on the survival of Lactobacillus casei and Bifidobacterium bifidum
    • Kim KI, Baek YJ, Yoon YH. 1996. Effect of rehydration media and immobilization in Ca-alginate on the survival of Lactobacillus casei and Bifidobacterium bifidum, Korean J Dairy Sci 18:193-8.
    • (1996) Korean J Dairy Sci , vol.18 , pp. 193-198
    • Kim, K.I.1    Baek, Y.J.2    Yoon, Y.H.3
  • 25
    • 36349024395 scopus 로고    scopus 로고
    • Effect of microencapsulation on viability and other characteristics in Lactobacillus acidophilus ATCC 43121
    • Kim S-J, Cho SY, Kim SH, Song O-J, Shin I-S, Cha DS, Park HJ. 2008. Effect of microencapsulation on viability and other characteristics in Lactobacillus acidophilus ATCC 43121. Lebensm Wiss Technol 41:493-500.
    • (2008) Lebensm Wiss Technol , vol.41 , pp. 493-500
    • Kim, S.-J.1    Cho, S.Y.2    Kim, S.H.3    Song, O.-J.4    Shin, I.-S.5    Cha, D.S.6    Park, H.J.7
  • 26
    • 2942744814 scopus 로고    scopus 로고
    • The influence of coating materials on some properties of alginate beads and survivability of microencapsulated probiotic bacteria
    • Krasaekoopt W, Bhandari B, Deeth H. 2004. The influence of coating materials on some properties of alginate beads and survivability of microencapsulated probiotic bacteria. Int Dairy J 14(8):737-43.
    • (2004) Int Dairy J , vol.14 , Issue.8 , pp. 737-743
    • Krasaekoopt, W.1    Bhandari, B.2    Deeth, H.3
  • 27
    • 64549125677 scopus 로고    scopus 로고
    • Water activity-temperature state diagrams of freeze dried L. acidophilus (La-5): influence of physical state on bacterial survival during storage
    • Kurtmann L, Carlsen CU, Skibted LH, Risbo J. 2009. Water activity-temperature state diagrams of freeze dried L. acidophilus (La-5): influence of physical state on bacterial survival during storage. Biotechnol Prog 25(1):265-70.
    • (2009) Biotechnol Prog , vol.25 , Issue.1 , pp. 265-270
    • Kurtmann, L.1    Carlsen, C.U.2    Skibted, L.H.3    Risbo, J.4
  • 28
    • 0000376703 scopus 로고
    • Water content and stability of low-moisture and intermediate-moisture foods
    • Labuza TP, Tannenbaum SR, Kavel M. 1969. Water content and stability of low-moisture and intermediate-moisture foods. Food Tech 24:35-9.
    • (1969) Food Tech , vol.24 , pp. 35-39
    • Labuza, T.P.1    Tannenbaum, S.R.2    Kavel, M.3
  • 29
    • 9344268283 scopus 로고    scopus 로고
    • Survival of freeze-dried Lactobacillus bulgaricus KFRI 673 in chitosan-coated calcium alginate microparticles
    • Lee JS, Cha DS, Park HJ. 2004. Survival of freeze-dried Lactobacillus bulgaricus KFRI 673 in chitosan-coated calcium alginate microparticles J Agric Food Chem 52:7300-5.
    • (2004) J Agric Food Chem , vol.52 , pp. 7300-7305
    • Lee, J.S.1    Cha, D.S.2    Park, H.J.3
  • 30
    • 0033981046 scopus 로고    scopus 로고
    • Survival of Bifidobacterium longum immobilized in calcium alginate beads in simulated gastric juices and bile salt solution
    • Lee K-Y, Heo T-R. 2000. Survival of Bifidobacterium longum immobilized in calcium alginate beads in simulated gastric juices and bile salt solution. Appl Environ Microbiol 66:869-73.
    • (2000) Appl Environ Microbiol , vol.66 , pp. 869-873
    • Lee, K.-Y.1    Heo, T.-R.2
  • 31
    • 0028838470 scopus 로고
    • Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying
    • Leslie SB, Israeli E, Lighthart B, Crowe JH, Crowe LM. 1995. Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying. Appl Environ Microbiol 61:3592-7.
    • (1995) Appl Environ Microbiol , vol.61 , pp. 3592-3597
    • Leslie, S.B.1    Israeli, E.2    Lighthart, B.3    Crowe, J.H.4    Crowe, L.M.5
  • 32
    • 78650517882 scopus 로고    scopus 로고
    • Preparation of alginate/chitosan/carboxymethyl chitosan complex microcapsules and application in Lactobacillus casei ATCC 393
    • Li XY, Chen XG, Sun ZW, Park HJ, Cha D-S. 2011. Preparation of alginate/chitosan/carboxymethyl chitosan complex microcapsules and application in Lactobacillus casei ATCC 393. Carbohydr Polym 83:1479-85.
    • (2011) Carbohydr Polym , vol.83 , pp. 1479-1485
    • Li, X.Y.1    Chen, X.G.2    Sun, Z.W.3    Park, H.J.4    Cha, D.-S.5
  • 33
    • 0025143274 scopus 로고
    • Enhancing the viability of Lactobacillus plantum inoculum by immobilizing the cells in calcium alginate beads incorporating cryoprotectants
    • Louis K, Upton M, McLoughlin A. 1990. Enhancing the viability of Lactobacillus plantum inoculum by immobilizing the cells in calcium alginate beads incorporating cryoprotectants. Appl Environ Microbiol 56:3112-6.
    • (1990) Appl Environ Microbiol , vol.56 , pp. 3112-3116
    • Louis, K.1    Upton, M.2    McLoughlin, A.3
  • 34
    • 80955170231 scopus 로고    scopus 로고
    • Non immunological models of protection. Fermented food. Fermentation and intestinal flora. Symposium Danone. 'Immunity and Probiotics', Denmark.
    • Malagelada JR. 1998. Non immunological models of protection. Fermented food. Fermentation and intestinal flora. Symposium Danone. 'Immunity and Probiotics', Denmark.
    • (1998)
    • Malagelada, J.R.1
  • 35
    • 80955162809 scopus 로고    scopus 로고
    • Minitab. Minitab 16 statistical software. Sidney, NSW: Minitab Pty Ltd. Available from
    • Minitab. 2010. Minitab 16 statistical software. Sidney, NSW: Minitab Pty Ltd. Available from
    • (2010)
  • 36
    • 69549123970 scopus 로고    scopus 로고
    • Principles and methods of microencapsulation of probiotic microorganisms: review
    • Mortazavian A, Razavi SH, Ehsani MR, Sohrabvandi S. 2007. Principles and methods of microencapsulation of probiotic microorganisms: review. Iranian J Biotechnol 5(1):1-18.
    • (2007) Iranian J Biotechnol , vol.5 , Issue.1 , pp. 1-18
    • Mortazavian, A.1    Razavi, S.H.2    Ehsani, M.R.3    Sohrabvandi, S.4
  • 37
    • 0021855147 scopus 로고
    • Survival of bacteria and fungi in relation to water activity and the solvent properties of water in biopolymer
    • Mugnier J, Jung G. 1985. Survival of bacteria and fungi in relation to water activity and the solvent properties of water in biopolymer. Appl Environ Microbiol 50:108-14.
    • (1985) Appl Environ Microbiol , vol.50 , pp. 108-114
    • Mugnier, J.1    Jung, G.2
  • 40
    • 0002819906 scopus 로고
    • Influence of water activity on food product quality and stability
    • Rockland LB, Nishi SK. 1980. Influence of water activity on food product quality and stability. Food Technol 34:42-51.
    • (1980) Food Technol , vol.34 , pp. 42-51
    • Rockland, L.B.1    Nishi, S.K.2
  • 41
    • 0036655346 scopus 로고    scopus 로고
    • Importance of glass transition and water activity to spray drying and stability of dairy powders
    • Ross YH. 2002. Importance of glass transition and water activity to spray drying and stability of dairy powders. Lait 82:475-84.
    • (2002) Lait , vol.82 , pp. 475-484
    • Ross, Y.H.1
  • 42
    • 0343396663 scopus 로고
    • Overview of the association of microbes with epithelial surfaces
    • Savage DC. 1984. Overview of the association of microbes with epithelial surfaces. Microecol Ther 14:169-82.
    • (1984) Microecol Ther , vol.14 , pp. 169-182
    • Savage, D.C.1
  • 43
    • 0032843620 scopus 로고    scopus 로고
    • Survival of Lactobacillus helveticus entrapped in Ca-alginate in relation to water content, storage and rehydration
    • Selmer-Olsen E, Sørhaug T, Birkeland S-E, Pehrson R. 1999. Survival of Lactobacillus helveticus entrapped in Ca-alginate in relation to water content, storage and rehydration. J Ind Microbiol Biotechnol 23:79-85.
    • (1999) J Ind Microbiol Biotechnol , vol.23 , pp. 79-85
    • Selmer-Olsen, E.1    Sørhaug, T.2    Birkeland, S.-E.3    Pehrson, R.4
  • 44
    • 28444475907 scopus 로고    scopus 로고
    • Effect of cryoprotectants, prebiotics and microencapsulation on survival of probiotic organisms in yoghurt and freeze-dried yoghurt
    • Shah NP, Capela P, Hay TKC. 2006. Effect of cryoprotectants, prebiotics and microencapsulation on survival of probiotic organisms in yoghurt and freeze-dried yoghurt Food Res Intl 39:203-11.
    • (2006) Food Res Intl , vol.39 , pp. 203-211
    • Shah, N.P.1    Capela, P.2    Hay, T.K.C.3
  • 45
    • 62549136085 scopus 로고    scopus 로고
    • An improved method of microencapsulation of probiotic bacteria for their stability in acidic and bile conditions during storage
    • Shah NP, Ding WK. 2009. An improved method of microencapsulation of probiotic bacteria for their stability in acidic and bile conditions during storage. J Food Sci 74(2):M53-61.
    • (2009) J Food Sci , vol.74 , Issue.2
    • Shah, N.P.1    Ding, W.K.2
  • 46
    • 34848818763 scopus 로고    scopus 로고
    • Endogenous β-glucosidase and β-galactosidase activities from selected probiotic micro-organisms and their role in isoflavone biotransformation in soymilk
    • Shah NP, Otieno DO. 2007. Endogenous β-glucosidase and β-galactosidase activities from selected probiotic micro-organisms and their role in isoflavone biotransformation in soymilk. J Appl Microbiol 103:910-7.
    • (2007) J Appl Microbiol , vol.103 , pp. 910-917
    • Shah, N.P.1    Otieno, D.O.2
  • 47
    • 0034357768 scopus 로고    scopus 로고
    • Microencapsulation of probiotic bacteria and their survival in frozen fermented dairy desserts
    • Shah NP, Ravula RR. 2000. Microencapsulation of probiotic bacteria and their survival in frozen fermented dairy desserts. Aust J Dairy Technol 55:139-44.
    • (2000) Aust J Dairy Technol , vol.55 , pp. 139-144
    • Shah, N.P.1    Ravula, R.R.2
  • 48
    • 5544255120 scopus 로고    scopus 로고
    • Effect of vacuum drying on protein-mannitol interactions: the physical state of mannitol and protein structure in the dried state
    • Sharma VK, Kalonia DS. 2004. Effect of vacuum drying on protein-mannitol interactions: the physical state of mannitol and protein structure in the dried state. AAPS Pharm Sci Tech 5(1):1-12.
    • (2004) AAPS Pharm Sci Tech , vol.5 , Issue.1 , pp. 1-12
    • Sharma, V.K.1    Kalonia, D.S.2
  • 49
    • 0027634018 scopus 로고
    • Improving survival of culture bacteria in frozen desserts-by microentrapment'
    • Sheu TY, Marshall RT Heymann H. 1993. Improving survival of culture bacteria in frozen desserts-by microentrapment' J Dairy Sci 76:1902-7.
    • (1993) J Dairy Sci , vol.76 , pp. 1902-1907
    • Sheu, T.Y.1    Marshall, R.T.2    Heymann, H.3
  • 50
    • 0034610465 scopus 로고    scopus 로고
    • Encapsulation of probiotic bacteria with alginate-starch and evaluation of survival in simulated gastrointestinal conditions and in yoghurt
    • Sultana K, Godward G, Reynolds N, Arumugaswamy R, Peiris P, Kailasapathy K. 2000. Encapsulation of probiotic bacteria with alginate-starch and evaluation of survival in simulated gastrointestinal conditions and in yoghurt. Int J Food Microbiol 62:47-55.
    • (2000) Int J Food Microbiol , vol.62 , pp. 47-55
    • Sultana, K.1    Godward, G.2    Reynolds, N.3    Arumugaswamy, R.4    Peiris, P.5    Kailasapathy, K.6
  • 51
    • 1642388498 scopus 로고    scopus 로고
    • Metabolic and biochemical responses of probiotic bacteria to oxygen
    • Talwalkar A, Kailasapathy K. 2003. Metabolic and biochemical responses of probiotic bacteria to oxygen J Dairy Sci 86:2537-46.
    • (2003) J Dairy Sci , vol.86 , pp. 2537-2546
    • Talwalkar, A.1    Kailasapathy, K.2
  • 52
    • 12444308939 scopus 로고    scopus 로고
    • Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride
    • Telang C, Yu I, Suryanarayanan R. 2003. Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride. Pharm Res 20:660-7.
    • (2003) Pharm Res , vol.20 , pp. 660-667
    • Telang, C.1    Yu, I.2    Suryanarayanan, R.3
  • 53
    • 36749016647 scopus 로고    scopus 로고
    • Accelerated storage testing of freeze-dried immobilized Lactobacillus acidophilus-fermented banana media
    • Tsen J-H, Lin Y-P, Huang H-Y, King VA-E. 2007. Accelerated storage testing of freeze-dried immobilized Lactobacillus acidophilus-fermented banana media. J Food Process Preserv 31:688-701.
    • (2007) J Food Process Preserv , vol.31 , pp. 688-701
    • Tsen, J.-H.1    Lin, Y.-P.2    Huang, H.-Y.3    King, V.-E.4
  • 54
    • 0027874935 scopus 로고
    • The role of carbohydrate fermentation in colon cancer prevention
    • van Munster IP, Nagengast FM. 1993. The role of carbohydrate fermentation in colon cancer prevention. Scand J Gastroenterol Suppl 200:80-6.
    • (1993) Scand J Gastroenterol Suppl , vol.200 , pp. 80-86
    • van Munster, I.P.1    Nagengast, F.M.2
  • 55
    • 10744228973 scopus 로고    scopus 로고
    • Lactic acid starter and probiotic bacteria, a comparative "in vitro" study of probiotic characteristics and biological barrier resistance
    • Vinderola CG, Reinheimer JA. 2003. Lactic acid starter and probiotic bacteria, a comparative "in vitro" study of probiotic characteristics and biological barrier resistance. Food Res Int 36:895-904.
    • (2003) Food Res Int , vol.36 , pp. 895-904
    • Vinderola, C.G.1    Reinheimer, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.