High glucose-induced apoptosis in human coronary artery endothelial cells involves up-regulation of death receptors

Cardiovascular Diabetology

Volumn 10, Issue , 2011, Pages

  Kageyama, Shun Ichiro ^a   Yokoo, Hiroki ^a   Tomita, Kengo ^a   Kageyama Yahara, Natsuko ^a   Uchimido, Ryo ^a   Matsuda, Naoyuki ^a   Yamamoto, Seiji ^a   Hattori, Yuichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH RECEPTOR; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; GLUCOSE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; FAS ASSOCIATED DEATH DOMAIN PROTEIN; STREPTOZOCIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; DNA FRAGMENTATION; ENDOTHELIUM CELL; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NICK END LABELING; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; UPREGULATION; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED DISORDER; CORONARY BLOOD VESSEL; CYTOLOGY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CORONARY VESSELS; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GLUCOSE; HUMANS; MALE; MICE; MICE, INBRED ICR; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SIGNAL TRANSDUCTION; STREPTOZOCIN; UP-REGULATION;

EID: 79961110359     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-10-73     Document Type: Article

References (48)

1. Lorenzi M, Cagliero E. Pathobiology of endothelial and other vascular cells in diabetes mellitus. Diabetes 1991, 40:653-659. 10.2337/diabetes.40.6.653, 2040380.
2. Hink U, Li H, Mollnau H, Oelze M, Matheis E, Hartmann M, Skatchkov M, Thaiss F, Stahl RA, Warnholtz A, Meinertz T, Griendling K, Harrison DG, Forstermann U, Muzel T. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 2001, 88:E14-E22.
3. Lorenzi M, Cagliero E, Toledo S. Glucose toxicity for human endothelial cells in culture: delayed replication, disturbed cell cycle, and accelerated death. Diabetes 1985, 34:621-627. 10.2337/diabetes.34.7.621, 3924693.
4. Lorenzi M, Nordberg JA, Toledo S. High glucose prolongs cell-cycle traversal of cultured human endothelial cells. Diabetes 1987, 36:1241-1267.
5. Lorenzi M, Montisano DF, Toledo S, Barrieux A. High glucose induces DNA damage in cultured human endothelial cells. J Clin Invest 1986, 77:322-325. 10.1172/JCI112295, 423344, 3944257.
6. Baumgartner-Parzer SM, Wagner L, Pettermann M, Grillari J, Gessl A, Waldhausl W. High-glucose-triggered apoptosis in cultured endothelial cells. Diabetes 1995, 44:1323-1327. 10.2337/diabetes.44.11.1323, 7589831.
7. Du XL, Sui GZ, Stockklauser-Farber K, Weiss J, Zink S, Schwippert B, Wu QX, Tschope D, Rosen P. Introduction of apoptosis by high proinsulin and glucose in cultured human umbilical vein endothelial cells is mediated by reactive oxygen species. Diabetologia 1998, 41:249-256. 10.1007/s001250050900, 9541163.
8. Wu QD, Wang JH, Fennessy F, Redmond HP, Bouchier-Hayes D. Taurine prevents high-glucose-induced human vascular endothelial cell apoptosis. Am J Physiol 1999, 277:C1229-C1238.
9. Ho FM, Liu SH, Liau CS, Huang PJ, Lin-Shiau SY. High glucose-induced apoptosis in human endothelial cells is mediated by sequential activation of c-Jun NH2-terminal kinase and caspase-3. Circulation 2000, 101:2618-2624.
10. Busik JV, Mohr S, Grant MB. Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators. Diabetes 2008, 57:1952-1965. 10.2337/db07-1520, 2453610, 18420487.
11. Mizutani M, Kern TS, Lorenzi M. Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. J Clin Invest 1996, 97:2883-2890. 10.1172/JCI118746, 507384, 8675702.
12. Behl Y, Krothapalli P, Desta T, Roy S, Graves DT. FOXO1 plays an important role in enhanced microvascular cell apoptosis and microvascular cell loss in type 1 and type 2 diabetic rats. Diabetes 2009, 58:917-925. 10.2337/db08-0537, 2661587, 19168598.
13. Frustaci A, Kajstura J, Chimenti C, Jakoniuk I, Leri A, Maseri A, Nadal-Ginard B, Anversa P. Myocardial cell death in human diabetes. Circ Res 2000, 87:1123-1132.
14. Ido Y, Carling D, Ruderman N. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. Diabetes 2002, 51:159-167.
15. Recchioni R, Marchesselli F, Moroni F, Pieri C. Apoptosis in human aortic endothelial cells induced by hyperglycemic condition involves mitochondria depolarization and is prevented by N-acetyl-L-cysteine. Metabolism 2002, 51:1384-1388. 10.1053/meta.2002.35579, 12404184.
16. Min C, Kang E, Yu SH, Shinn SH, Kim YS. Advanced glycation and products induce apoptosis and procoagulant activity in cultured human umbilical vein endothelial cells. Diabetes Res Clin Pract 1999, 46:197-202. 10.1016/S0168-8227(99)00094-7, 10624785.
17. Chen J, Brodsky SV, Goligorsky DM, Hampel DJ, Li H, Gross SS, Goligorsky MS. Glycated collagen I induces premature senescence-like phenotype changes in endothelial cells. Circ Res 2002, 90:1290-1298. 10.1161/01.RES.0000022161.42655.98, 12089067.
18. Sakuma H, Yamamoto M, Okumura M, Kojima T, Maruyama T, Yasuda K. High glucose inhibits in human coronary artery smooth muscle cells by increasing bcl-xL and bfl-1/A1. Am J Physiol Cell Physiol 2002, 283:C422-C428.
19. Korsmeyer SJ. BCL-2 gene family and the regulation of programmed cell death. Cancer Res 1999, 59(Suppl 7):1693s-1700s.
20. Green DR, Kroemer G. The pathophysiology of mitochondrial cell death. Science 2004, 305:626-629. 10.1126/science.1099320, 15286356.
21. Li Y, Wu H, Khardori R, Song Y-H, Lu YW, Geng Y-J. Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis. Biochem Biophys Res Commun 2009, 384:259-264. 10.1016/j.bbrc.2009.04.113, 19406106.
22. Nakagami H, Morishita R, Yamamoto K, Yoshimura S, Taniyama Y, Aoki M, Matsubara H, Kim S, Kaneda Y, Ogihara T. Phosphorylation of p38 mitogen-activated protein kinase downstream of Bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells. Diabetes 2001, 50:1472-1481. 10.2337/diabetes.50.6.1472, 11375350.
23. Thorburn A. Death receptor-induced cell killing. Cell Signal 2004, 16:139-144. 10.1016/j.cellsig.2003.08.007, 14636884.
24. Lavrik I, Golks A, Krammer PH. Death receptor signaling. J Cell Sci 2005, 118:265-267. 10.1242/jcs.01610, 15654015.
25. Su X, Hu Q, Kristan JM, Costa C, Shen Y, Gero D, Matis LA, Wang Y. Significant role for Fas in the pathogenesis of autoimmune diabetes. J Immunol 2000, 164:2523-2532.
26. Allison J, Thomas HE, Catterall T, Kay TW, Strasser A. Transgenic expression of dominant-negative Fas-associated death domain protein in β cells protects against Fas ligand-induced apoptosis and reduces spontaneous diabetes in nonobese diabetic mice. J Immunol 2005, 175:293-301.
27. Dudek NL, Thomas HE, Mariana L, Sutherland RM, Allison J, Estella E, Angstetra E, Trapani JA, Santamaria P, Lew AM, Kay TW. Cytotoxic T-cells from T-cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways. Diabetes 2006, 55:2412-2418. 10.2337/db06-0109, 16936188.
28. Kim YH, Kim S, Kim KA, Yagita H, Kayagaki N, Kim KW, Lee MS. Apoptosis of pancreatic B cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interation in autoimmune diabetes. Eur J Immunol 1999, 29:455-465. 10.1002/(SICI)1521-4141(199902)29:02<455::AID-IMMU455>3.0.CO;2-A, 10064061.
29. Kim S, Kim KA, Hwang DY, Lee TH, Kayagaki N, Yagita H, Lee MS. Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved. J Immunol 2000, 164:2931-2936.
30. Arai Y, Kondo T, Tanabe K, Zhao Q-L, Li F-J, Ogawa R, Li M, Kasuya M. Enhancement of hyperthermia-induced apoptosis by local anesthetics on human histiocytic lymphoma U937 cells. J Biol Chem 2002, 277:18986-18993. 10.1074/jbc.M108084200, 11861640.
31. Kobayashi T, Taguchi K, Yasuhiro T, Matsumoto T, Kamata K. Impairment of PI3-K/Akt pathway underlies attenuated endothelial function in aorta of type 2 diabetic mouse model. Hypertension 2004, 44:956-962. 10.1161/01.HYP.0000147559.10261.a7, 15505117.
32. Takenouchi Y, Kobayashi T, Taguchi K, Matsumoto T, Kamata K. Gender differences in endothelial function in aortas from type 2 diabetic model mouse. J Pharmacol Sci 2009, 111:91-99. 10.1254/jphs.09133FP, 19721331.
33. Masiello P, Broca C, Gross R, Roye M, Manteghetti M, Hillaire-Buys D, Novelli M, Ribes G. Experimental NIDDM. Development of a new model in adult rats administered streptozotocin and nicotinamide. Diabetes 1998, 47:224-229. 10.2337/diabetes.47.2.224, 9519717.
34. Kamiyama K, Matsuda N, Yamamoto S, Takano K, Takano Y, Yamazaki H, Kageyama S, Yokoo H, Nagata T, Hatakeyama N, Tsukada K, Hattori Y. Modulation of glucocorticoid receptor expression, inflammation, and cell apoptosis in septic guinea pig lungs using methylprednisolone. Am J Physiol Lung Cell Mol Physiol 2008, 295:L998-L1006. 10.1152/ajplung.00459.2007, 18836031.
35. Vischer UM. von Willebrand factor, endothelial dysfunction, and cardiovascular disease. J Thromb Haemost 2006, 4:1186-1193. 10.1111/j.1538-7836.2006.01949.x, 16706957.
36. Thorburn A. Death receptor-induced cell killing. Cell Signal 2004, 16:139-144. 10.1016/j.cellsig.2003.08.007, 14636884.
37. Moller DE. Potential role of TNF-α in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab 2000, 11:212-217. 10.1016/S1043-2760(00)00272-1, 10878750.
38. Morohoshi M, Fujisawa K, Uchimura I, Numano F. Glucose-dependent interleukin 6 and tumor necrosis factor production by human peripheral blood monocytes in vitro. Diabetes 1996, 45:954-959. 10.2337/diabetes.45.7.954, 8666148.
39. Guha M, Bai W, Nadler JL, Natarajan R. Molecular mechanisms of tumor necrosis factor α gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and -independent pathways. J Biol Chem 2000, 275:17728-17739. 10.1074/jbc.275.23.17728, 10837498.
40. Shanmugam N, Reddy MA, Guha M, Natarajan R. High glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells. Diabetes 2003, 52:1256-1264. 10.2337/diabetes.52.5.1256, 12716761.
41. Min W, Bin ZW, Quan ZB, Hui ZJ, Sheng FG. The signal transduction pathway of PKC/NF-κB/c-fos may be involved in the influence of high glucose on the cardiomyocytes of neonatal rats. Cardiovasc Diabetology 2009, 8:8.
42. Maedler K, Spinas GA, Lehmann R, Sergeev P, Weber M, Fontana A, Kaiser N, Donath MY. Glucose induces β-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes 2001, 50:1683-1690. 10.2337/diabetes.50.8.1683, 11473025.
43. Kim F, Tysseling KA, Rice J, Gallis B, Haji L, Giachelli CM, Raines EW, Corson MA, Schwartz MW. Activation of IKKβ by glucose is necessary and sufficient to impair insulin signaling and nitric oxide production in endothelial cells. J Mol Cell Cardiol 2005, 39:327-334. 10.1016/j.yjmcc.2005.05.009, 15978611.
44. Toma L, Stancu CS, Botez GM, Sima AV, Simionescu M. Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose. Biochem Biophys Res Commun 2009, 390:877-882. 10.1016/j.bbrc.2009.10.066, 19850013.
45. Alikhani M, Alikhani Z, Graves D. FOXO1a functions as a master switch that regulates gene expression necessary for TNF-induced fibroblast apoptosis. J Biol Chem 2005, 280:12096-12102.
46. Jain SK, Kannan K, Lim G, McVie R, Bocchini JA. Hyperketonemia increases tumor necrosis factor-α secretion in cultured U937 monocytes and type 1 diabetic patients and is apparently mediated by oxidative stress and cAMP deficiency. Diabetes 2002, 51:2287-2293. 10.2337/diabetes.51.7.2287, 12086962.
47. El-Seweidy MM, El-Swefy SE, Ameen RS, Hashem RM. Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in STZ diabetic rats. Pharmacol Res 2002, 45:391-398. 10.1006/phrs.2002.0979, 12123627.
48. Joussen AM, Poulaki V, Mitsiades N, Cai W, Suzuma I, Pak J, Ju S-T, Rook SL, Esser P, Mitsiades C, Kirchhof B, Adamis AP, Aiello LP. Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes. FASEB J 2003, 17:76-78.