Activation of IKKβ by glucose is necessary and sufficient to impair insulin signaling and nitric oxide production in endothelial cells

Journal of Molecular and Cellular Cardiology

Volumn 39, Issue 2, 2005, Pages 327-334

  Kim, Francis ^a   Tysseling, Kelly A ^a   Rice, Julie ^b   Gallis, Byron ^a   Haji, Lutfiyah ^a   Giachelli, Cecilia M ^b   Raines, Elaine W ^c   Corson, Marshall A ^a   Schwartz, Michael W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b University of Washington   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Endothelial cells; eNOS; Glucose; IKK ; Nitric oxide

Indexed keywords

ACETYLSALICYLIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; I KAPPA B KINASE INHIBITOR; INSULIN; NITRIC OXIDE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; SERINE; TYROSINE; I KAPPA B KINASE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GLUCONEOGENESIS; HYPERGLYCEMIA; INCUBATION TIME; INSULIN RELEASE; INSULIN RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; BIOSYNTHESIS; CATTLE; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION; METABOLISM;

BOVINAE;

ANIMALS; ASPIRIN; CATTLE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GENE EXPRESSION; GLUCOSE; I-KAPPA B KINASE; INSULIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SIGNAL TRANSDUCTION;

EID: 22244486298     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2005.05.009     Document Type: Article

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