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Volumn 6, Issue 8, 2011, Pages

Anti-inflammatory effect of fluvastatin on IL-8 production induced by pseudomonas aeruginosa and aspergillus fumigatus antigens in cystic fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BACTERIAL ANTIGEN; CHOLESTEROL; CORTICOSTEROID; DEOXYRIBONUCLEASE; FARNESYL DIPHOSPHATE; FLUINDOSTATIN; FUNGUS ANTIGEN; GERANYLGERANYL PYROPHOSPHATE; GUANOSINE TRIPHOSPHATASE; INTERLEUKIN 8; MEVALONIC ACID; PYRROLE; ANTIINFLAMMATORY AGENT; INDOLE DERIVATIVE; LIPOPOLYSACCHARIDE; MONOUNSATURATED FATTY ACID; TERPENE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 79961090074     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022655     Document Type: Article
Times cited : (23)

References (53)
  • 2
    • 70349759567 scopus 로고    scopus 로고
    • Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences
    • Vandivier RW, Richens TR, Horstmann SA, deCathelineau AM, Ghosh M, et al. (2009) Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences. Am J Physiol Lung Cell Mol Physiol 297: L677-L686.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297 , pp. 677-686
    • Vandivier, R.W.1    Richens, T.R.2    Horstmann, S.A.3    deCathelineau, A.M.4    Ghosh, M.5
  • 3
    • 36848999782 scopus 로고    scopus 로고
    • Clinical use of Ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis
    • Konstan MW, Schluchter MD, Xue W, Davis PB, (2007) Clinical use of Ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis. Am J Respir Crit Care Med 176: 1084-1089.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1084-1089
    • Konstan, M.W.1    Schluchter, M.D.2    Xue, W.3    Davis, P.B.4
  • 4
    • 34548038663 scopus 로고    scopus 로고
    • High-dose ibuprofen in cystic fibrosis: Canadian safety and effectiveness trial
    • Lands LC, Milner R, Cantin AM, Manson D, Corey M, (2007) High-dose ibuprofen in cystic fibrosis: Canadian safety and effectiveness trial. J Pediatr 151: 249-254.
    • (2007) J Pediatr , vol.151 , pp. 249-254
    • Lands, L.C.1    Milner, R.2    Cantin, A.M.3    Manson, D.4    Corey, M.5
  • 5
    • 0000306390 scopus 로고    scopus 로고
    • Statins do more than just lower cholesterol
    • Vaughan CJ, Murphy MB, Buckley BM, (1996) Statins do more than just lower cholesterol. Lancet 348: 1079-1082.
    • (1996) Lancet , vol.348 , pp. 1079-1082
    • Vaughan, C.J.1    Murphy, M.B.2    Buckley, B.M.3
  • 6
    • 0037309378 scopus 로고    scopus 로고
    • A novel anti-inflammatory role for simvastatin in inflammatory arthritis
    • Leung BP, Sattar N, Crilly A, Prach M, McCarey DW, et al. (2003) A novel anti-inflammatory role for simvastatin in inflammatory arthritis. J Immunol 170: 1524-1530.
    • (2003) J Immunol , vol.170 , pp. 1524-1530
    • Leung, B.P.1    Sattar, N.2    Crilly, A.3    Prach, M.4    McCarey, D.W.5
  • 7
    • 1342282244 scopus 로고    scopus 로고
    • A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma
    • McKay A, Leung BP, McInnes IB, Thomson NC, Liew FY, (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. J Immunol 172: 2903-2908.
    • (2004) J Immunol , vol.172 , pp. 2903-2908
    • McKay, A.1    Leung, B.P.2    McInnes, I.B.3    Thomson, N.C.4    Liew, F.Y.5
  • 8
    • 33845604074 scopus 로고    scopus 로고
    • Simvastatin stimulates interleukine-1β secretion through an isoprenylation-dependent mechanism
    • Lindhom MW, Nilsson J, (2007) Simvastatin stimulates interleukine-1β secretion through an isoprenylation-dependent mechanism. Vasc Pharmacol 46: 91-96.
    • (2007) Vasc Pharmacol , vol.46 , pp. 91-96
    • Lindhom, M.W.1    Nilsson, J.2
  • 9
    • 11344277830 scopus 로고    scopus 로고
    • Statins for atherosclerosis - as good as it gets?
    • Ehrenstein MR, Jury EC, Mauri C, (2005) Statins for atherosclerosis - as good as it gets? N Engl J Med 352: 73-75.
    • (2005) N Engl J Med , vol.352 , pp. 73-75
    • Ehrenstein, M.R.1    Jury, E.C.2    Mauri, C.3
  • 10
    • 0033868728 scopus 로고    scopus 로고
    • Simvastatin inhibits the monocyte expression of pro-inflammatory cytokines in patients with hypercholesterolemia
    • Ferro D, Parrotto S, Basili S, Alessandri C, Violi F, (2000) Simvastatin inhibits the monocyte expression of pro-inflammatory cytokines in patients with hypercholesterolemia. J Am Coll Cardiol 36: 427-431.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 427-431
    • Ferro, D.1    Parrotto, S.2    Basili, S.3    Alessandri, C.4    Violi, F.5
  • 11
    • 77956542993 scopus 로고    scopus 로고
    • Statin treatment and mortality in bacterial infections-a systematic review and meta-analysis
    • Björkhem-Bergman L, Bergman P, Andersson J, Lindh JD, (2010) Statin treatment and mortality in bacterial infections-a systematic review and meta-analysis. PLoS One 5: e10702.
    • (2010) PLoS One , vol.5
    • Björkhem-Bergman, L.1    Bergman, P.2    Andersson, J.3    Lindh, J.D.4
  • 12
    • 37549021118 scopus 로고    scopus 로고
    • The use of statins and lung function in current and former smokers
    • Keddissi JI, Younis WG, Chbeir EA, Daher NN, Dernaika TA, et al. (2007) The use of statins and lung function in current and former smokers. Chest 132: 1764-1771.
    • (2007) Chest , vol.132 , pp. 1764-1771
    • Keddissi, J.I.1    Younis, W.G.2    Chbeir, E.A.3    Daher, N.N.4    Dernaika, T.A.5
  • 13
    • 26944462695 scopus 로고    scopus 로고
    • Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs
    • Lee JH, Lee DS, Kim EK, Choe KH, Oh YM, et al. (2005) Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs. Am J Respir Crit Care Med 172: 987-993.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 987-993
    • Lee, J.H.1    Lee, D.S.2    Kim, E.K.3    Choe, K.H.4    Oh, Y.M.5
  • 14
    • 70349878485 scopus 로고    scopus 로고
    • Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond
    • Zeki AA, Franzi L, Last J, Kenyon NJ, (2009) Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond. Am J Respir Crit Care Med 180: 731-740.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 731-740
    • Zeki, A.A.1    Franzi, L.2    Last, J.3    Kenyon, N.J.4
  • 16
    • 33747073147 scopus 로고    scopus 로고
    • Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury
    • Yao HW, Mao LG, Zhu JP, (2006) Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury. Clin Exp Pharmacol Physiol 33: 793-797.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 793-797
    • Yao, H.W.1    Mao, L.G.2    Zhu, J.P.3
  • 17
    • 0032717657 scopus 로고    scopus 로고
    • Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions
    • Hartung T, Doecke WD, Bundschuh D, Foote MA, Gantner F, et al. (1999) Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions. Clin Pharmacol Ther 66: 415-424.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 415-424
    • Hartung, T.1    Doecke, W.D.2    Bundschuh, D.3    Foote, M.A.4    Gantner, F.5
  • 18
    • 1242342724 scopus 로고    scopus 로고
    • Plasma interferon-gamma and interleukin-10 concentrations in systemic meningococcal disease compared with severe systemic Gram-positive septic shock
    • Bjerre A, Brusletto B, Høiby EA, Kierulf P, Brandtzaeg P, (2004) Plasma interferon-gamma and interleukin-10 concentrations in systemic meningococcal disease compared with severe systemic Gram-positive septic shock. Crit Care Med 32: 433-438.
    • (2004) Crit Care Med , vol.32 , pp. 433-438
    • Bjerre, A.1    Brusletto, B.2    Høiby, E.A.3    Kierulf, P.4    Brandtzaeg, P.5
  • 19
    • 10644249246 scopus 로고    scopus 로고
    • The novel phosphodiesterase 4 inhibitor, CI-1044, inhibits LPS-induced TNF-alpha production in whole blood from COPD patients
    • Ouagued M, Martin-Chouly CA, Brinchault G, Leportier-Comoy C, Depincé A, et al. (2005) The novel phosphodiesterase 4 inhibitor, CI-1044, inhibits LPS-induced TNF-alpha production in whole blood from COPD patients. Pulm Pharmacol Ther 18: 49-54.
    • (2005) Pulm Pharmacol Ther , vol.18 , pp. 49-54
    • Ouagued, M.1    Martin-Chouly, C.A.2    Brinchault, G.3    Leportier-Comoy, C.4    Depincé, A.5
  • 20
    • 0026058195 scopus 로고
    • Microbiology of airway disease in patients with cystic fibrosis
    • Gilligan PH, (1991) Microbiology of airway disease in patients with cystic fibrosis. Clin Microbiol Rev 4: 35-51.
    • (1991) Clin Microbiol Rev , vol.4 , pp. 35-51
    • Gilligan, P.H.1
  • 21
    • 51249090136 scopus 로고    scopus 로고
    • Doxycycline reduces lipopolysaccharide-induced inflammatory mediator secretion in macrophage and ex vivo human whole blood models
    • Cazalis J, Bodet C, Gagnon G, Grenier D, (2008) Doxycycline reduces lipopolysaccharide-induced inflammatory mediator secretion in macrophage and ex vivo human whole blood models. J Periodontol 79: 1762-1768.
    • (2008) J Periodontol , vol.79 , pp. 1762-1768
    • Cazalis, J.1    Bodet, C.2    Gagnon, G.3    Grenier, D.4
  • 22
    • 59949090500 scopus 로고    scopus 로고
    • Aspergillus fumigatus germ tube growth and not conidia ingestion induces expression of inflammatory mediator genes in the human lung epithelial cell line A549
    • Bellanger AP, Millon L, Khoufache K, Rivollet D, Bièche I, et al. (2009) Aspergillus fumigatus germ tube growth and not conidia ingestion induces expression of inflammatory mediator genes in the human lung epithelial cell line A549. J Med Microbiol 58: 174-179.
    • (2009) J Med Microbiol , vol.58 , pp. 174-179
    • Bellanger, A.P.1    Millon, L.2    Khoufache, K.3    Rivollet, D.4    Bièche, I.5
  • 23
    • 0033036459 scopus 로고    scopus 로고
    • Cytokine responses during mucosal infections: role in disease pathogenesis and host defence
    • Svanborg C, Godaly G, Hedlund M, (1999) Cytokine responses during mucosal infections: role in disease pathogenesis and host defence. Curr Opin Microbiol 2: 99-105.
    • (1999) Curr Opin Microbiol , vol.2 , pp. 99-105
    • Svanborg, C.1    Godaly, G.2    Hedlund, M.3
  • 24
    • 33748422072 scopus 로고    scopus 로고
    • Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-κB activation via EGFR transactivation in a lung epithelial cell line
    • Kuwahara I, Lillehoj EP, Lu WJ, Singh IS, Isohama Y, et al. (2006) Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-κB activation via EGFR transactivation in a lung epithelial cell line. Am J Physiol Lung Cell Mol Physiol 291: L407-L416.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , pp. 407-416
    • Kuwahara, I.1    Lillehoj, E.P.2    Lu, W.J.3    Singh, I.S.4    Isohama, Y.5
  • 25
    • 77957275161 scopus 로고    scopus 로고
    • Monocytes from children with clinically stable cystic fibrosis show enhanced expression of Toll-like receptor 4
    • Sturges NC, Wikström ME, Winfield KR, Gard SE, Brennan S, et al. (2010) Monocytes from children with clinically stable cystic fibrosis show enhanced expression of Toll-like receptor 4. Pediatr Pulm 45: 883-889.
    • (2010) Pediatr Pulm , vol.45 , pp. 883-889
    • Sturges, N.C.1    Wikström, M.E.2    Winfield, K.R.3    Gard, S.E.4    Brennan, S.5
  • 26
    • 8644227614 scopus 로고    scopus 로고
    • Systemic inflammatory mediators and cystic fibrosis genotype
    • Augarten A, Paret G, Avneri I, Akons H, Aviram M, et al. (2004) Systemic inflammatory mediators and cystic fibrosis genotype. Clin Exp Med 4: 99-102.
    • (2004) Clin Exp Med , vol.4 , pp. 99-102
    • Augarten, A.1    Paret, G.2    Avneri, I.3    Akons, H.4    Aviram, M.5
  • 28
    • 0027600805 scopus 로고
    • Cytokines in sputum and serum from patients with cystic fibrosis and chronic Pseudomonas aeruginosa infection as markers of destructive inflammation in the lungs
    • Kronborg G, Hansen MB, Svenson M, Fomsgaard A, Hoiby N, et al. (1993) Cytokines in sputum and serum from patients with cystic fibrosis and chronic Pseudomonas aeruginosa infection as markers of destructive inflammation in the lungs. Pediatr Pulmonol 15: 292-297.
    • (1993) Pediatr Pulmonol , vol.15 , pp. 292-297
    • Kronborg, G.1    Hansen, M.B.2    Svenson, M.3    Fomsgaard, A.4    Hoiby, N.5
  • 31
    • 0034833605 scopus 로고    scopus 로고
    • Whole blood cytokine response as a measure of immunotoxicity
    • Langezaal I, Coecke S, Hartung T, (2001) Whole blood cytokine response as a measure of immunotoxicity. Toxicol In Vitro 15: 313-318.
    • (2001) Toxicol In Vitro , vol.15 , pp. 313-318
    • Langezaal, I.1    Coecke, S.2    Hartung, T.3
  • 33
    • 0033596281 scopus 로고    scopus 로고
    • Effect of statins on risk of coronary disease. A meta-analysis of randomized controlled trials
    • LaRosa JC, He J, Vupputuri S, (1999) Effect of statins on risk of coronary disease. A meta-analysis of randomized controlled trials. JAMA 282: 2340-2346.
    • (1999) JAMA , vol.282 , pp. 2340-2346
    • LaRosa, J.C.1    He, J.2    Vupputuri, S.3
  • 35
    • 78751488978 scopus 로고    scopus 로고
    • Successful treatment of acute lung injury with pitavastatin in septic mice: potential role of glucocorticoid receptor expression in alveolar macrophages
    • Takano K, Yamamoto S, Tomita K, Takashina M, Yokoo H, et al. (2010) Successful treatment of acute lung injury with pitavastatin in septic mice: potential role of glucocorticoid receptor expression in alveolar macrophages. J Pharmacol Exp Ther 336: 381-390.
    • (2010) J Pharmacol Exp Ther , vol.336 , pp. 381-390
    • Takano, K.1    Yamamoto, S.2    Tomita, K.3    Takashina, M.4    Yokoo, H.5
  • 36
    • 0032127168 scopus 로고    scopus 로고
    • LPS-induced cytokine production and expression of LPS-receptors by peripheral blood mononuclear cells of patients with familial hypercholesterolemia and the effect of HMG-CoA reductase inhibitors
    • De Bont N, Netea MG, Rovers C, Smilde T, Demacker PN, et al. (1998) LPS-induced cytokine production and expression of LPS-receptors by peripheral blood mononuclear cells of patients with familial hypercholesterolemia and the effect of HMG-CoA reductase inhibitors. Atherosclerosis 139: 147-152.
    • (1998) Atherosclerosis , vol.139 , pp. 147-152
    • de Bont, N.1    Netea, M.G.2    Rovers, C.3    Smilde, T.4    Demacker, P.N.5
  • 37
    • 0029858008 scopus 로고    scopus 로고
    • Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras
    • Goldman F, Hohl RJ, Crabtree J, Lewis-Tibesar K, Koretzky G, (1996) Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras. Blood 88: 4611-4619.
    • (1996) Blood , vol.88 , pp. 4611-4619
    • Goldman, F.1    Hohl, R.J.2    Crabtree, J.3    Lewis-Tibesar, K.4    Koretzky, G.5
  • 38
    • 0030292168 scopus 로고    scopus 로고
    • Inhibitory effect of fluvastatin, an HMG-CoA reductase inhibitor, on the expression of adhesion molecules on human monocyte cell line
    • Niwa S, Totsuka T, Hayashi S, (1996) Inhibitory effect of fluvastatin, an HMG-CoA reductase inhibitor, on the expression of adhesion molecules on human monocyte cell line. Int J Immunopharmacol 18: 669-675.
    • (1996) Int J Immunopharmacol , vol.18 , pp. 669-675
    • Niwa, S.1    Totsuka, T.2    Hayashi, S.3
  • 39
    • 0028362140 scopus 로고
    • Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells
    • Terkeltaub R, Solan J, Barry M, Santoro D, Bokoch GM, (1994) Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells. J Leukocyte Biol 55: 749-755.
    • (1994) J Leukocyte Biol , vol.55 , pp. 749-755
    • Terkeltaub, R.1    Solan, J.2    Barry, M.3    Santoro, D.4    Bokoch, G.M.5
  • 40
    • 45749148199 scopus 로고    scopus 로고
    • Simvastatin inhibits Staphylococcus aureus host cell invasion through modulation of isoprenoid intermediates
    • Horn MP, Knecht SM, Rushing FL, Birdsong J, Siddall CP, et al. (2008) Simvastatin inhibits Staphylococcus aureus host cell invasion through modulation of isoprenoid intermediates. J Pharmacol Exp Ther 326: 135-143.
    • (2008) J Pharmacol Exp Ther , vol.326 , pp. 135-143
    • Horn, M.P.1    Knecht, S.M.2    Rushing, F.L.3    Birdsong, J.4    Siddall, C.P.5
  • 41
    • 33947305316 scopus 로고    scopus 로고
    • Simvastatin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery
    • Chello M, Anselmi A, Spadaccio C, Patti G, Goffredo C, et al. (2007) Simvastatin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery. Ann Thorac Surg 83: 1374-1380.
    • (2007) Ann Thorac Surg , vol.83 , pp. 1374-1380
    • Chello, M.1    Anselmi, A.2    Spadaccio, C.3    Patti, G.4    Goffredo, C.5
  • 42
    • 14944362300 scopus 로고    scopus 로고
    • A role for hydroxy-methylglutaryl coenzyme A reductase in pulmonary inflammation and host defense
    • Fessler MB, Young SK, Jeyaseelan S, Lieber JG, Arndt PG, et al. (2005) A role for hydroxy-methylglutaryl coenzyme A reductase in pulmonary inflammation and host defense. Am J Respir Crit Care Med 171: 606-615.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 606-615
    • Fessler, M.B.1    Young, S.K.2    Jeyaseelan, S.3    Lieber, J.G.4    Arndt, P.G.5
  • 43
    • 52949087117 scopus 로고    scopus 로고
    • Simvastatin attenuates lipopolysaccharide-induced airway mucus hypersecretion in rats
    • Ou XM, Wang BD, Wen FQ, Feng YL, Huang XY, et al. (2008) Simvastatin attenuates lipopolysaccharide-induced airway mucus hypersecretion in rats. Chin Med J 121: 1680-1687.
    • (2008) Chin Med J , vol.121 , pp. 1680-1687
    • Ou, X.M.1    Wang, B.D.2    Wen, F.Q.3    Feng, Y.L.4    Huang, X.Y.5
  • 44
    • 33745373880 scopus 로고    scopus 로고
    • Simvastatin decreases IL-6 and IL-8 production in epithelial cells
    • Sakoda K, Yamamoto M, Negishi Y, Liao JK, Node K, et al. (2006) Simvastatin decreases IL-6 and IL-8 production in epithelial cells. J Dent Res 85: 520-523.
    • (2006) J Dent Res , vol.85 , pp. 520-523
    • Sakoda, K.1    Yamamoto, M.2    Negishi, Y.3    Liao, J.K.4    Node, K.5
  • 46
    • 0035129882 scopus 로고    scopus 로고
    • Stimulation of inflammatory responses in vitro and in vivo by lipophilic HMG-CoA reductase inhibitors
    • Kiener PA, Davis PM, Murray JL, Youssef S, Rankin BM, et al. (2001) Stimulation of inflammatory responses in vitro and in vivo by lipophilic HMG-CoA reductase inhibitors. Int Immunopharmacol 1: 105-118.
    • (2001) Int Immunopharmacol , vol.1 , pp. 105-118
    • Kiener, P.A.1    Davis, P.M.2    Murray, J.L.3    Youssef, S.4    Rankin, B.M.5
  • 47
    • 0027185879 scopus 로고
    • Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG CoA reductase
    • Corsini A, Mazzotti M, Raiteri M, Soma MR, Gabbiani G, et al. (1993) Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG CoA reductase. Atherosclerosis 101: 117-125.
    • (1993) Atherosclerosis , vol.101 , pp. 117-125
    • Corsini, A.1    Mazzotti, M.2    Raiteri, M.3    Soma, M.R.4    Gabbiani, G.5
  • 48
    • 65449179667 scopus 로고    scopus 로고
    • Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers
    • Shyamsundar M, McKeown ST, O'Kane CM, Craig TR, Brown V, et al. (2009) Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am J Respir Crit Care Med 179: 1107-1114.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 1107-1114
    • Shyamsundar, M.1    McKeown, S.T.2    O'Kane, C.M.3    Craig, T.R.4    Brown, V.5
  • 49
    • 38149017709 scopus 로고    scopus 로고
    • Fluvastatin reduces increased blood monocyte Toll-like receptor 4 expression in whole blood from patients with chronic heart failure
    • Földes G, von Haehling S, Okonko DO, Jankowska EA, Poole-Wilson PA, et al. (2008) Fluvastatin reduces increased blood monocyte Toll-like receptor 4 expression in whole blood from patients with chronic heart failure. Int J Cardiol 124: 80-85.
    • (2008) Int J Cardiol , vol.124 , pp. 80-85
    • Földes, G.1    von Haehling, S.2    Okonko, D.O.3    Jankowska, E.A.4    Poole-Wilson, P.A.5
  • 50
    • 0141996311 scopus 로고    scopus 로고
    • Rho GTPases as therapeutic targets for the treatment of inflammatory diseases
    • Zhao D, Pothoulakis C, (2003) Rho GTPases as therapeutic targets for the treatment of inflammatory diseases. Expert Opin Ther Targets 7: 583-592.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 583-592
    • Zhao, D.1    Pothoulakis, C.2
  • 51
    • 0345358534 scopus 로고    scopus 로고
    • Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells
    • Kreiselmeier NE, Kraynack NC, Corey DA, Kelley TJ, (2003) Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. AJP- Lung Physiol 285: L1286-L1295.
    • (2003) AJP - Lung Physiol , vol.285 , pp. 1286-1295
    • Kreiselmeier, N.E.1    Kraynack, N.C.2    Corey, D.A.3    Kelley, T.J.4
  • 52
    • 0141615605 scopus 로고    scopus 로고
    • The phenotypic consequences of CFTR mutations
    • Rowntree RK, Harris A, (2003) The phenotypic consequences of CFTR mutations. Ann Hum Genet 67: 471-485.
    • (2003) Ann Hum Genet , vol.67 , pp. 471-485
    • Rowntree, R.K.1    Harris, A.2


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