Doxycycline reduces lipopolysaccharide-induced inflammatory mediator secretion in macrophage and ex vivo human whole blood models

Journal of Periodontology

Volumn 79, Issue 9, 2008, Pages 1762-1768

  Cazalis, Julia ^a   Bodet, Charles ^a   Gagnon, Guy ^a   Grenier, Daniel ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Cytokine; Doxycycline; Lipopolysaccharide; Macrophage; Periodontitis; Whole blood

Indexed keywords

AKT1 PROTEIN, HUMAN; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; AUTACOID; DOXYCYCLINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ADULT; ARTICLE; BLOOD; DRUG EFFECT; FEMALE; HUMAN; MACROPHAGE; MALE; MICROBIOLOGY; MIDDLE AGED; PERIODONTITIS; PHOSPHORYLATION; PORPHYROMONAS GINGIVALIS;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ADULT; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; DOXYCYCLINE; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 9; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERIODONTITIS; PHOSPHORYLATION; PORPHYROMONAS GINGIVALIS; PROTO-ONCOGENE PROTEINS C-AKT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 51249090136     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2008.080051     Document Type: Article

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