Simvastatin attenuates lipopolysaccharide-induced airway mucus hypersecretion in rats

Chinese Medical Journal

Volumn 121, Issue 17, 2008, Pages 1680-1687

  Ou, Xue Mei ^a,b   Wang, Bai Ding ^a,b   Wen, Fu Qiang ^a,b   Feng, Yu Lin ^a,b   Huang, Xiang Yang ^a,b   Xiao, Jun ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Lipopolysaccharide; Mitogen activated protein kinases p38; Mucus hypersecretion; RhoA; Simvastatin

Indexed keywords

INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MUCIN 5AC; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SIMVASTATIN; TUMOR NECROSIS FACTOR ALPHA;

AIRWAY MUCUS HYPERSECRETION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CELL HYPERPLASIA; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GOBLET CELL; IMMUNOHISTOCHEMISTRY; LUNG LAVAGE; MALE; NEUTROPHIL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT DISEASE; TISSUE LEVEL; WESTERN BLOTTING;

EID: 52949087117     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200809010-00018     Document Type: Article

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