Effect of Pseudomonas infection on weight loss, lung mechanics, and cytokines in mice

American Journal of Respiratory and Critical Care Medicine

Volumn 161, Issue 1, 2000, Pages 271-279

  Van Heeckeren, Anna M ^a,b   Tscheikuna, Jamsak ^a   Walenga, Ronald W ^a   Konstan, Michael W ^a   Davis, Pamela B ^a   Erokwu, Bernie ^a   Haxhiu, Musa A ^a   Ferkol, Thomas W ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY PLETHYSMOGRAPHY; CACHEXIA; CONTROLLED STUDY; CYSTIC FIBROSIS; GRAM NEGATIVE INFECTION; LEUKOCYTE COUNT; LUNG COMPLIANCE; LUNG FUNCTION; LUNG LAVAGE; LUNG MECHANICS; LUNG RESISTANCE; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SKELETAL MUSCLE; WEIGHT REDUCTION;

EID: 0033958501     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.161.1.9903019     Document Type: Article

References (25)

1. 1. Konstan, M. W., and M. Berger. 1993. Infection and inflammation of the lung in cystic fibrosis. In P. B. Davis, editor. Cystic Fibrosis. Marcel Dekker, New York. 219-276.
2. 2. Khan, T. Z., J. S. Wagener, T. Bost, J. Martinez, F. J. Accurso, and D. W. Riches. 1995. Early pulmonary inflammation in infants with cystic fibrosis. Am. J. Respir. Crit. Care Med. 151:1075-1082.
3. 3. Noah, T. L., H. R. Black, P. W. Cheng, R. E. Wood, and M. W. Leigh. 1997. Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis. J. Infect. Dis. 175:638-647.
4. 4. Cash, H. A., D. E. Woods, B. McCullough, W. G. Johanson, Jr., and J. A. Bass. 1979. A rat model of chronic respiratory infection with Pseudomonas aeruginosa. Am. Rev. Respir. Dis. 119:453-459.
5. 5. Starke, J. R., M. S. Edwards, C. Langston, and C. J. Baker. 1987. A mouse model of chronic pulmonary infection with Pseudomonas aeruginosa and Pseudomonas cepacia. Pediatr. Res. 22:698-702.
6. 6. Konstan, M. W., K. M. Vargo, and P. B. Davis. 1990. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection: implications for antiinflammatory therapy in cystic fibrosis. Am. Rev. Respir. Dis. 141:186-192.
7. 7. van Heeckeren, A., R. Walenga, M. W. Konstan, T. Bonfield, P. B. Davis, and T. Ferkol. 1997. Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa. J. Clin. Invest. 100:2810-2815.
8. 8. Gosselin, D., M. M. Stevenson, E. A. Cowley, U. Griesenbach, D. H. Eidelman, M. Boule, M. F. Tam, G. Kent, E. Skamene, L. C. Tsui, and D. Radzioch. 1998. Impaired ability of CFTR knockout mice to control lung infection with Pseudomonas aeruginosa. Am. J. Respir. Crit. Care Med. 157:1253-1262.
9. 9. Kraemer, R., A. Rudeberg, B. Hadorn, and E. Rossi. 1978. Relative underweight in cystic fibrosis and its prognostic value. Acta Paediatr. Scand. 67:33-37.
10. 10. Corey, M., F. J. McLaughlin, M. Williams, and H. Levison. 1988. A comparison of survival, growth, and pulmonary function in patients with cystic fibrosis in Boston and Toronto. J. Clin. Epidemiol. 41:583-591.
11. 11. Naon, H., S. Hack, M. T. Shelton, R. C. Gotthoffer, and D. Gozal. 1993. Resting energy expenditure: evolution during antibiotic treatment for pulmonary exacerbation in cystic fibrosis. Chest 103:1819-1825.
12. 12. Steinkamp, G., A. Drommer, and H. von der Hardt. 1993. Resting energy expenditure before and after treatment for Pseudomonas aeruginosa infection in patients with cystic fibrosis. Am. J. Clin. Nutr. 57: 685-689.
13. 13. Rennard, S. I., G. Basset, D. Lecossier, K. M. O'Donnell, P. Pinkston, P. G. Martin, and R. G. Crystal. 1986. Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution. J. Appl. Physiol. 60:532-538.
14. 14. Shepherd, R. W., T. L. Holt, L. Vasques-Velasquez, W. A. Coward, A. Prentice, and A. Lucas. 1988. Increased energy expenditure in young children with cystic fibrosis. Lancet 1:1300-1303.
15. 15. Fong, Y., L. L. Moldawer, M. Marano, H. Wei, A. Barber, K. Manogue, K. J. Tracey, G. Kuo, D. A. Fischman, and A. Cerami. 1989. Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins. Am. J. Physiol. 256:R659-R665.
16. 16. Tracey, K. J., H. Wei, K. R. Manogue, Y. Fong, D. G. Hesse, H. T. Nguyen, G. C. Kuo, B. Beutler, R. S. Cotran, and A. Cerami. 1988. Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation. J. Exp. Med. 167:1211-1227.
17. 17. Moldawer, L. L., G. Svaninger, J. Gelin, and K. G. Lundholm. 1987. Interleukin 1 and tumor necrosis factor do not regulate protein balance in skeletal muscle. Am. J. Physiol. 253:C766-C773.
18. 18. Elborn, J. S., S. M. Cordon, P. J. Western, I. A. Macdonald, and D. J. Shale. 1993. Tumour necrosis factor-alpha, resting energy expenditure and cachexia in cystic fibrosis. Clin. Sci. (Colch). 85:563-568.
19. 19. Brown, M. A., W. J. Morgan, P. R. Finley, and P. Scuderi. 1991. Circulating levels of tumor necrosis factor and interleukin-1 in cystic fibrosis [see comments]. Pediatr. Pulmonol. 10:86-91.
20. 20. Nixon. L. S., B. Yung, S. C. Bell, J. S. Elborn, and D. J. Shale. 1998. Circulating immunoreactive interleukin-6 in cystic fibrosis. Am. J. Respir. Crit. Care Med. 157:1764-1769.
21. 21. Oldenburg, H. S., M. A. Rogy, D. D. Lazarus, K. J. Van Zee, B. P. Keeler, R. A. Chizzonite, S. F. Lowry, and L. L. Moldawer. 1993. Cachexia and the acute-phase protein response in inflammation are regulated by interleukin-6. Eur. J. Immunol. 23:1889-1894.
22. 22. Xing, Z., J. Gauldie, G. Cox, H. Baumann, M. Jordana, X. F. Lei, and M. K. Achong. 1998. IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J. Clin. Invest. 101:311-320.
23. 23. Matthys, P., and A. Billiau. 1997. Cytokines and cachexia. Nutrition 13:763-770.
24. 24. Konstan, M. W., P. J. Byard, C. L. Hoppel, and P. B. Davis. 1995. Effect of high-dose ibuprofen in patients with cystic fibrosis. N. Engl. J. Med. 332:848-854.
25. 25. Chmiel, J. F., M. W. Konstan, J. E. Knesebeck, J. B. Hilliard, T. L. Bonfield, D. V. Dawson, and M. Berger. 1998. IL-10 attenuates excessive inflammation in chronic Pseudomonas infection in mice. Am. J. Respir. Crit. Care Med. 160:2040-2047.