Selection of a CXCR4 antagonist from a human heavy chain CDR3-derived phage library

FEBS Journal

Volumn 278, Issue 16, 2011, Pages 2867-2878

  Chevigné, Andy ^a   Fischer, Aurélie ^a   Mathu, Julie ^a   Counson, Manuel ^a   Beaupain, Nadia ^a   Plesséria, Jean Marc ^a   Schmit, Jean Claude ^a,b   Deroo, Sabrina ^a  

^a Retrovirology Laboratory Luxembourg   (Luxembourg)

^b CENTRE HOSPITALIER DE LUXEMBOURG   (Luxembourg)

Author keywords

CXCR4 antagonist; HCDR3; natural sequence randomization; peptide repertoire; phage display

Indexed keywords

ASPARTIC ACID; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; GLYCINE; IMMUNOGLOBULIN M; SERINE; TYROSINE;

AMINO ACID SEQUENCE; ARTICLE; COMPLEMENTARITY DETERMINING REGION; COMPLEMENTARITY DETERMINING REGION 3; CONTROLLED STUDY; FREQUENCY ANALYSIS; HEAVY CHAIN; HUMAN; MOLECULAR LIBRARY; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MOTIF; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; COMPLEMENTARITY DETERMINING REGIONS; GENE LIBRARY; HUMANS; IMMUNOGLOBULIN M; PEPTIDE LIBRARY; RECEPTORS, CXCR4;

EID: 79961027249     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08208.x     Document Type: Article

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