Mimic peptides bonding specifically with the first and second extracellular loops of the CC chemokine receptor 5 derived from a phage display peptide library are potent inhibitors of experimental autoimmune encephalomyelitis

Inflammation Research

Volumn 60, Issue 8, 2011, Pages 759-767

  Zheng, Hui Min ^a   Jiang, Yun ^a   Wang, Ju Rong ^a   Gong, Xue Lian ^a   Guo, Bao Yu ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

CCR5; EAE; Mimic peptides

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; DNA; GLUTAMYLTHREONYLSERYLSERYLALANYLALANYLLEUCINE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; POLYPEPTIDE; SERYLLEUCYLPROLYLLEUCYLPROLYLLYSYLPROLINE; SERYLTHREONYLPHENYLALANYLTHREONYLTHREONYLLEUCINE; THREONYLPROPYLISOLEUCYLPROPYLGLUTAMYLLEUCYLLEUCINE; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALITIS; ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA SEQUENCE; DRUG ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; INFLAMMATORY CELL; LYMPHOCYTIC INFILTRATION; MONOCYTE; MOUSE; NONHUMAN; PHAGE DISPLAY; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; RECEPTORS, CCR5; SPINAL CORD;

EID: 80051799051     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-011-0331-8     Document Type: Article

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