Non-immunized natural human heavy chain CDR3 repertoires allow the isolation of high affinity peptides mimicking a human influenza hemagglutinin epitope

Molecular Immunology

Volumn 45, Issue 5, 2008, Pages 1366-1373

  Deroo, Sabrina ^a   Fischer, Aurélie ^a   Beaupain, Nadia ^a   Counson, Manuel ^a   Boutonnet, Nathalie ^b   Pletinckx, Jurgen ^b   Loverix, Stefan ^b   Beirnaert, Els ^c   De Haard, Hans ^c   Schmit, Jean Claude ^a,d   Lasters, Ignace ^b  

^a Retrovirology Laboratory Luxembourg   (Luxembourg)

^b Algonomics   (Belgium)

^c ABLYNX NV   (Belgium)

^d CENTRE HOSPITALIER DE LUXEMBOURG   (Luxembourg)

Author keywords

Antibody; HCDR3; Peptide libraries of human origin; Phage display

Indexed keywords

CYSTEINE; EPITOPE; GLYCINE; HEMAGGLUTININ; PEPTIDE DERIVATIVE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; HEAVY CHAIN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANTIBODIES; ANTIBODY AFFINITY; COMPLEMENTARITY DETERMINING REGIONS; EPITOPES; HEMAGGLUTININS; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN M; INFLUENZA, HUMAN; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; PROTEIN STRUCTURE, SECONDARY;

EID: 37449003961     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.09.001     Document Type: Article

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