메뉴 건너뛰기




Volumn 2, Issue 4, 2011, Pages

TRIM E3 ligases in HIV infection: Can these intrinsic immunity factors be harnessed for novel antiviral strategies?

Author keywords

Antiviral mechanisms; HIV; HIV pathogenesis; Innate immunity; TRIM E3 ligases; TRIM22; TRIM5a; Type 1 interferon

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CHEMOKINE RECEPTOR CCR5; LEUKOCYTE ANTIGEN; LIGASE; MESSENGER RNA; TRIPARTITE MOTIF CONTAINING E3 LIGASE; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG;

EID: 79960984530     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (62)
  • 1
    • 0020596551 scopus 로고
    • Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
    • Barre-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, Gruest J, et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 1983; 220:868-71.
    • (1983) Science , vol.220 , pp. 868-871
    • Barre-Sinoussi, F.1    Chermann, J.C.2    Rey, F.3    Nugeyre, M.T.4    Chamaret, S.5    Gruest, J.6
  • 2
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
    • Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998; 338:853-60.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella Jr., F.J.1    Delaney, K.M.2    Moorman, A.C.3    Loveless, M.O.4    Fuhrer, J.5    Satten, G.A.6
  • 3
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn NM, Forthal DN, Harro CD, Judson FN, Mayer KH, Para MF. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis 2005; 191:654-65.
    • (2005) J Infect Dis , vol.191 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3    Judson, F.N.4    Mayer, K.H.5    Para, M.F.6
  • 4
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cellmediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, testof-concept trial
    • Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, Li D, et al. Efficacy assessment of a cellmediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, testof-concept trial. Lancet 2008; 372:1881-93.
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3    Fitzgerald, D.W.4    Mogg, R.5    Li, D.6
  • 6
    • 44049108744 scopus 로고    scopus 로고
    • Toward an AIDS vaccine
    • Walker BD, Burton DR. Toward an AIDS vaccine. Science 2008; 320:760-4.
    • (2008) Science , vol.320 , pp. 760-764
    • Walker, B.D.1    Burton, D.R.2
  • 7
    • 50449090525 scopus 로고    scopus 로고
    • An HIV vaccine-challenges and prospects
    • Johnston MI, Fauci AS. An HIV vaccine-challenges and prospects. N Engl J Med 2008; 359:888-90.
    • (2008) N Engl J Med , vol.359 , pp. 888-890
    • Johnston, M.I.1    Fauci, A.S.2
  • 9
    • 77949384495 scopus 로고    scopus 로고
    • Immunology and the elusive AIDS vaccine
    • Virgin HW, Walker BD. Immunology and the elusive AIDS vaccine. Nature 2010; 464:224-31.
    • (2010) Nature , vol.464 , pp. 224-231
    • Virgin, H.W.1    Walker, B.D.2
  • 10
    • 77956450707 scopus 로고    scopus 로고
    • The 2010 scientific strategic plan of the Global HIV Vaccine Enterprise
    • The Global HIV Vaccine Enterprise
    • The Global HIV Vaccine Enterprise. The 2010 scientific strategic plan of the Global HIV Vaccine Enterprise. Nat Med 2010; 16:981-9.
    • (2010) Nat Med , vol.16 , pp. 981-989
  • 11
    • 0037043699 scopus 로고    scopus 로고
    • Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
    • Sheehy AM, Gaddis NC, Choi JD, Malim MH. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 2002; 418:646-50.
    • (2002) Nature , vol.418 , pp. 646-650
    • Sheehy, A.M.1    Gaddis, N.C.2    Choi, J.D.3    Malim, M.H.4
  • 12
    • 77953035055 scopus 로고    scopus 로고
    • Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: Implications for therapeutics
    • Albin JS, Harris RS. Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics. Expert Rev Mol Med 2010; 12:4.
    • (2010) Expert Rev Mol Med , vol.12 , pp. 4
    • Albin, J.S.1    Harris, R.S.2
  • 13
    • 38549095979 scopus 로고    scopus 로고
    • Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
    • Neil SJ, Zang T, Bieniasz PD. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 2008; 451:425-30.
    • (2008) Nature , vol.451 , pp. 425-430
    • Neil, S.J.1    Zang, T.2    Bieniasz, P.D.3
  • 14
    • 41849116366 scopus 로고    scopus 로고
    • The interferoninduced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein
    • Van Damme N, Goff D, Katsura C, Jorgenson RL, Mitchell R, Johnson MC, et al. The interferoninduced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 2008; 3:245-52.
    • (2008) Cell Host Microbe , vol.3 , pp. 245-252
    • van Damme, N.1    Goff, D.2    Katsura, C.3    Jorgenson, R.L.4    Mitchell, R.5    Johnson, M.C.6
  • 15
    • 1542288934 scopus 로고    scopus 로고
    • The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
    • Stremlau M, Owens CM, Perron MJ, Kiessling M, Autissier P, Sodroski J. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004; 427:848-53.
    • (2004) Nature , vol.427 , pp. 848-853
    • Stremlau, M.1    Owens, C.M.2    Perron, M.J.3    Kiessling, M.4    Autissier, P.5    Sodroski, J.6
  • 16
    • 3242876747 scopus 로고    scopus 로고
    • Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1
    • Sayah DM, Sokolskaja E, Berthoux L, Luban J. Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature 2004; 430:569-73.
    • (2004) Nature , vol.430 , pp. 569-573
    • Sayah, D.M.1    Sokolskaja, E.2    Berthoux, L.3    Luban, J.4
  • 17
    • 0028856825 scopus 로고
    • Early replication block of human immunodeficiency virus type 1 in monkey cells
    • Shibata R, Sakai H, Kawamura M, Tokunaga K, Adachi A. Early replication block of human immunodeficiency virus type 1 in monkey cells. J Gen Virol 1995; 76:2723-30.
    • (1995) J Gen Virol , vol.76 , pp. 2723-2730
    • Shibata, R.1    Sakai, H.2    Kawamura, M.3    Tokunaga, K.4    Adachi, A.5
  • 18
    • 0029927037 scopus 로고    scopus 로고
    • Restriction of HIV-1 (subtype B) replication at the entry step in rhesus macaque cells
    • Himathongkham S, Luciw PA. Restriction of HIV-1 (subtype B) replication at the entry step in rhesus macaque cells. Virology 1996; 219:485-8.
    • (1996) Virology , vol.219 , pp. 485-488
    • Himathongkham, S.1    Luciw, P.A.2
  • 19
    • 0037213619 scopus 로고    scopus 로고
    • Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells
    • Owens CM, Yang PC, Gottlinger H, Sodroski J. Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells. J Virol 2003; 77:726-31.
    • (2003) J Virol , vol.77 , pp. 726-731
    • Owens, C.M.1    Yang, P.C.2    Gottlinger, H.3    Sodroski, J.4
  • 20
    • 54949126675 scopus 로고    scopus 로고
    • TRIM family proteins and their emerging roles in innate immunity
    • Ozato K, Shin DM, Chang TH, Morse HC, 3rd. TRIM family proteins and their emerging roles in innate immunity. Nat Rev Immunol 2008; 8:849-60.
    • (2008) Nat Rev Immunol , vol.8 , pp. 849-860
    • Ozato, K.1    Shin, D.M.2    Chang, T.H.3    Morse III, H.C.4
  • 22
    • 33646842883 scopus 로고    scopus 로고
    • Subclassification of the RBCC/ TRIM superfamily reveals a novel motif necessary for microtubule binding
    • Short KM, Cox TC. Subclassification of the RBCC/ TRIM superfamily reveals a novel motif necessary for microtubule binding. J Biol Chem 2006; 281:8970-80.
    • (2006) J Biol Chem , vol.281 , pp. 8970-8980
    • Short, K.M.1    Cox, T.C.2
  • 23
    • 34247341367 scopus 로고    scopus 로고
    • TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
    • Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, et al. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 2007; 446:916-20.
    • (2007) Nature , vol.446 , pp. 916-920
    • Gack, M.U.1    Shin, Y.C.2    Joo, C.H.3    Urano, T.4    Liang, C.5    Sun, L.6
  • 24
    • 0038148965 scopus 로고    scopus 로고
    • BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta
    • Xu L, Yang L, Moitra PK, Hashimoto K, Rallabhandi P, Kaul S, et al. BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta. Exp Cell Res 2003; 288:84-93.
    • (2003) Exp Cell Res , vol.288 , pp. 84-93
    • Xu, L.1    Yang, L.2    Moitra, P.K.3    Hashimoto, K.4    Rallabhandi, P.5    Kaul, S.6
  • 25
    • 40349116307 scopus 로고    scopus 로고
    • TRIM E3 ligases interfere with early and late stages of the retroviral life cycle
    • Uchil PD, Quinlan BD, Chan WT, Luna JM, Mothes W. TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. PLoS Pathog 2008; 4:16.
    • (2008) PLoS Pathog , vol.4 , pp. 16
    • Uchil, P.D.1    Quinlan, B.D.2    Chan, W.T.3    Luna, J.M.4    Mothes, W.5
  • 26
    • 27244444559 scopus 로고    scopus 로고
    • TRIM family proteins: Retroviral restriction and antiviral defence
    • Nisole S, Stoye JP, Saib A. TRIM family proteins: retroviral restriction and antiviral defence. Nat Rev Microbiol 2005; 3:799-808.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 799-808
    • Nisole, S.1    Stoye, J.P.2    Saib, A.3
  • 27
    • 40949163764 scopus 로고    scopus 로고
    • TRIM30 alpha negatively regulates TLR-mediated NFkappaB activation by targeting TAB2 and TAB3 for degradation
    • Shi M, Deng W, Bi E, Mao K, Ji Y, Lin G, et al. TRIM30 alpha negatively regulates TLR-mediated NFkappaB activation by targeting TAB2 and TAB3 for degradation. Nat Immunol 2008; 9:369-77.
    • (2008) Nat Immunol , vol.9 , pp. 369-377
    • Shi, M.1    Deng, W.2    Bi, E.3    Mao, K.4    Ji, Y.5    Lin, G.6
  • 28
    • 33645794537 scopus 로고    scopus 로고
    • Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor
    • Stremlau M, Perron M, Lee M, Li Y, Song B, Javanbakht H, et al. Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. Proc Natl Acad Sci USA 2006; 103:5514-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5514-5519
    • Stremlau, M.1    Perron, M.2    Lee, M.3    Li, Y.4    Song, B.5    Javanbakht, H.6
  • 29
    • 34249669155 scopus 로고    scopus 로고
    • Rhesus monkey TRIM5alpha restricts HIV-1 production through rapid degradation of viral Gag polyproteins
    • Sakuma R, Noser JA, Ohmine S, Ikeda Y. Rhesus monkey TRIM5alpha restricts HIV-1 production through rapid degradation of viral Gag polyproteins. Nat Med 2007; 13:631-5.
    • (2007) Nat Med , vol.13 , pp. 631-635
    • Sakuma, R.1    Noser, J.A.2    Ohmine, S.3    Ikeda, Y.4
  • 30
    • 40349094838 scopus 로고    scopus 로고
    • The interferon response inhibits HIV particle production by induction of TRIM22
    • Barr SD, Smiley JR, Bushman FD. The interferon response inhibits HIV particle production by induction of TRIM22. PLoS Pathog 2008; 4:1000007.
    • (2008) PLoS Pathog , vol.4 , pp. 1000007
    • Barr, S.D.1    Smiley, J.R.2    Bushman, F.D.3
  • 31
    • 79955377543 scopus 로고    scopus 로고
    • TRIM5 is an innate immune sensor for the retrovirus capsid lattice
    • Pertel T, Hausmann S, Morger D, Zuger S, Guerra J, Lascano J, et al. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 2011; 472:361-5.
    • (2011) Nature , vol.472 , pp. 361-365
    • Pertel, T.1    Hausmann, S.2    Morger, D.3    Zuger, S.4    Guerra, J.5    Lascano, J.6
  • 32
    • 79955429978 scopus 로고    scopus 로고
    • TRIM22 inhibits HIV-1 transcription independently of its e3 ubiquitin ligase activity, Tat and NF{kappa}B-responsive long terminal repeat elements
    • Kajaste-Rudnitski A, Marelli SS, Pultrone C, Pertel T, Uchil PD, Mechti N, et al. TRIM22 inhibits HIV-1 transcription independently of its e3 ubiquitin ligase activity, Tat and NF{kappa}B-responsive long terminal repeat elements. J Virol 2011; 85:5183-96.
    • (2011) J Virol , vol.85 , pp. 5183-5196
    • Kajaste-Rudnitski, A.1    Marelli, S.S.2    Pultrone, C.3    Pertel, T.4    Uchil, P.D.5    Mechti, N.6
  • 33
    • 35348871305 scopus 로고    scopus 로고
    • Alpha interferon enhances TRIM5alpha-mediated antiviral activities in human and rhesus monkey cells
    • Sakuma R, Mael AA, Ikeda Y. Alpha interferon enhances TRIM5alpha-mediated antiviral activities in human and rhesus monkey cells. J Virol 2007; 81:10201-6.
    • (2007) J Virol , vol.81 , pp. 10201-10206
    • Sakuma, R.1    Mael, A.A.2    Ikeda, Y.3
  • 34
    • 78650065600 scopus 로고    scopus 로고
    • Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection
    • Singh R, Gaiha G, Werner L, McKim K, Mlisana K, Luban J, et al. Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. J Virol 2011; 85:208-16.
    • (2011) J Virol , vol.85 , pp. 208-216
    • Singh, R.1    Gaiha, G.2    Werner, L.3    McKim, K.4    Mlisana, K.5    Luban, J.6
  • 36
    • 77956896934 scopus 로고    scopus 로고
    • A 5' extended IFN-stimulating response element is crucial for IFNgamma-induced tripartite motif 22 expression via interaction with IFN regulatory factor-1
    • Gao B, Wang Y, Xu W, Duan Z, Xiong S. A 5' extended IFN-stimulating response element is crucial for IFNgamma-induced tripartite motif 22 expression via interaction with IFN regulatory factor-1. J Immunol 2010; 185:2314-23.
    • (2010) J Immunol , vol.185 , pp. 2314-2323
    • Gao, B.1    Wang, Y.2    Xu, W.3    Duan, Z.4    Xiong, S.5
  • 37
    • 43649094723 scopus 로고    scopus 로고
    • Type I interferondependent and-independent expression of tripartite motif proteins in immune cells
    • Rajsbaum R, Stoye JP, O'Garra A. Type I interferondependent and-independent expression of tripartite motif proteins in immune cells. Eur J Immunol 2008; 38:619-30.
    • (2008) Eur J Immunol , vol.38 , pp. 619-630
    • Rajsbaum, R.1    Stoye, J.P.2    O'Garra, A.3
  • 38
    • 51649097483 scopus 로고    scopus 로고
    • Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties
    • Sardiello M, Cairo S, Fontanella B, Ballabio A, Meroni G. Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties. BMC Evol Biol 2008; 8:225.
    • (2008) BMC Evol Biol , vol.8 , pp. 225
    • Sardiello, M.1    Cairo, S.2    Fontanella, B.3    Ballabio, A.4    Meroni, G.5
  • 39
    • 33646556096 scopus 로고    scopus 로고
    • Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection
    • Si Z, Vandegraaff N, O'Huigin C, Song B, Yuan W, Xu C, et al. Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection. Proc Natl Acad Sci USA 2006; 103:7454-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7454-7459
    • Si, Z.1    Vandegraaff, N.2    O'Huigin, C.3    Song, B.4    Yuan, W.5    Xu, C.6
  • 40
    • 37849007655 scopus 로고    scopus 로고
    • Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals
    • Sawyer SL, Emerman M, Malik HS. Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. PLoS Pathog 2007; 3:197.
    • (2007) PLoS Pathog , vol.3 , pp. 197
    • Sawyer, S.L.1    Emerman, M.2    Malik, H.S.3
  • 41
    • 14544281087 scopus 로고    scopus 로고
    • Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain
    • Sawyer SL, Wu LI, Emerman M, Malik HS. Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci USA 2005; 102:2832-7.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2832-2837
    • Sawyer, S.L.1    Wu, L.I.2    Emerman, M.3    Malik, H.S.4
  • 42
    • 28244477117 scopus 로고    scopus 로고
    • Adaptive evolution of primate TRIM5alpha, a gene restricting HIV-1 infection
    • Liu HL, Wang YQ, Liao CH, Kuang YQ, Zheng YT, Su B. Adaptive evolution of primate TRIM5alpha, a gene restricting HIV-1 infection. Gene 2005; 362:109-16.
    • (2005) Gene , vol.362 , pp. 109-116
    • Liu, H.L.1    Wang, Y.Q.2    Liao, C.H.3    Kuang, Y.Q.4    Zheng, Y.T.5    Su, B.6
  • 43
    • 10944259799 scopus 로고    scopus 로고
    • The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates
    • Song B, Gold B, O'Huigin C, Javanbakht H, Li X, Stremlau M, et al. The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates. J Virol 2005; 79:6111-21.
    • (2005) J Virol , vol.79 , pp. 6111-6121
    • Song, B.1    Gold, B.2    O'Huigin, C.3    Javanbakht, H.4    Li, X.5    Stremlau, M.6
  • 44
    • 34250840762 scopus 로고    scopus 로고
    • Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha
    • Newman RM, Hall L, Connole M, Chen GL, Sato S, Yuste E, et al. Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha. Proc Natl Acad Sci USA 2006; 103:19134-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19134-19139
    • Newman, R.M.1    Hall, L.2    Connole, M.3    Chen, G.L.4    Sato, S.5    Yuste, E.6
  • 45
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
    • Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996; 273:1856-62.
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1    Carrington, M.2    Winkler, C.3    Huttley, G.A.4    Smith, M.W.5    Allikmets, R.6
  • 46
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiplyexposed individuals to HIV-1 infection
    • Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiplyexposed individuals to HIV-1 infection. Cell 1996; 86:367-77.
    • (1996) Cell , vol.86 , pp. 367-377
    • Liu, R.1    Paxton, W.A.2    Choe, S.3    Ceradini, D.4    Martin, S.R.5    Horuk, R.6
  • 47
    • 78650084232 scopus 로고    scopus 로고
    • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
    • Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, et al. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 2010; 330:1551-7.
    • (2010) Science , vol.330 , pp. 1551-1557
    • Pereyra, F.1    Jia, X.2    McLaren, P.J.3    Telenti, A.4    de Bakker, P.I.5    Walker, B.D.6
  • 48
    • 33749135723 scopus 로고    scopus 로고
    • Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection
    • Javanbakht H, An P, Gold B, Petersen DC, O'Huigin C, Nelson GW, et al. Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection. Virology 2006; 354:15-27.
    • (2006) Virology , vol.354 , pp. 15-27
    • Javanbakht, H.1    An, P.2    Gold, B.3    Petersen, D.C.4    O'Huigin, C.5    Nelson, G.W.6
  • 49
    • 30044432359 scopus 로고    scopus 로고
    • High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans
    • Sawyer SL, Wu LI, Akey JM, Emerman M, Malik HS. High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Curr Biol 2006; 16:95-100.
    • (2006) Curr Biol , vol.16 , pp. 95-100
    • Sawyer, S.L.1    Wu, L.I.2    Akey, J.M.3    Emerman, M.4    Malik, H.S.5
  • 50
    • 33144458585 scopus 로고    scopus 로고
    • Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection
    • Speelmon EC, Livingston-Rosanoff D, Li SS, Vu Q, Bui J, Geraghty DE, et al. Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection. J Virol 2006; 80:2463-71.
    • (2006) J Virol , vol.80 , pp. 2463-2471
    • Speelmon, E.C.1    Livingston-Rosanoff, D.2    Li, S.S.3    Vu, Q.4    Bui, J.5    Geraghty, D.E.6
  • 53
    • 34648840100 scopus 로고    scopus 로고
    • The presence of the Trim5alpha escape mutation H87Q in the capsid of late stage HIV-1 variants is preceded by a prolonged asymptomatic infection phase
    • Kootstra NA, Navis M, Beugeling C, van Dort KA, Schuitemaker H. The presence of the Trim5alpha escape mutation H87Q in the capsid of late stage HIV-1 variants is preceded by a prolonged asymptomatic infection phase. AIDS 2007; 21:2015-23.
    • (2007) AIDS , vol.21 , pp. 2015-2023
    • Kootstra, N.A.1    Navis, M.2    Beugeling, C.3    van Dort, K.A.4    Schuitemaker, H.5
  • 54
    • 44849132669 scopus 로고    scopus 로고
    • Establishing a cohort at high risk of HIV infection in South Africa: Challenges and experiences of the CAPRISA 002 acute infection study
    • van Loggerenberg F, Mlisana K, Williamson C, Auld SC, Morris L, Gray CM, et al. Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study. PLoS ONE 2008; 3:1954.
    • (2008) PLoS ONE , vol.3 , pp. 1954
    • van Loggerenberg, F.1    Mlisana, K.2    Williamson, C.3    Auld, S.C.4    Morris, L.5    Gray, C.M.6
  • 55
    • 67650675663 scopus 로고    scopus 로고
    • Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection
    • Sewram S, Singh R, Kormuth E, Werner L, Mlisana K, Karim SS, et al. Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection. J Infect Dis 2009; 199:1657-63.
    • (2009) J Infect Dis , vol.199 , pp. 1657-1663
    • Sewram, S.1    Singh, R.2    Kormuth, E.3    Werner, L.4    Mlisana, K.5    Karim, S.S.6
  • 56
    • 33750996702 scopus 로고    scopus 로고
    • Human TRIM5alpha mediated restriction of different HIV-1 subtypes and Lv2 sensitive and insensitive HIV-2 variants
    • Kaumanns P, Hagmann I, Dittmar MT. Human TRIM5alpha mediated restriction of different HIV-1 subtypes and Lv2 sensitive and insensitive HIV-2 variants. Retrovirology 2006; 3:79.
    • (2006) Retrovirology , vol.3 , pp. 79
    • Kaumanns, P.1    Hagmann, I.2    Dittmar, M.T.3
  • 57
    • 77958498224 scopus 로고    scopus 로고
    • Vaccine adjuvants: Putting innate immunity to work
    • Coffman RL, Sher A, Seder RA. Vaccine adjuvants: putting innate immunity to work. Immunity 2010; 33:492-503.
    • (2010) Immunity , vol.33 , pp. 492-503
    • Coffman, R.L.1    Sher, A.2    Seder, R.A.3
  • 58
    • 79956079190 scopus 로고    scopus 로고
    • Immunological mechanisms of vaccination
    • Pulendran B, Ahmed R. Immunological mechanisms of vaccination. Nat Immunol 2011; 131:509-17.
    • (2011) Nat Immunol , vol.131 , pp. 509-517
    • Pulendran, B.1    Ahmed, R.2
  • 59
    • 0035796503 scopus 로고    scopus 로고
    • PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator
    • Regad T, Saib A, Lallemand-Breitenbach V, Pandolfi PP, de The H, Chelbi-Alix MK. PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator. EMBO J 2001; 20:3495-505.
    • (2001) EMBO J , vol.20 , pp. 3495-3505
    • Regad, T.1    Saib, A.2    Lallemand-Breitenbach, V.3    Pandolfi, P.P.4    de The, H.5    Chelbi-Alix, M.K.6
  • 60
    • 0034973563 scopus 로고    scopus 로고
    • Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: Interference with early steps of viral replication
    • Turelli P, Doucas V, Craig E, Mangeat B, Klages N, Evans R, et al. Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: interference with early steps of viral replication. Mol Cell 2001; 7:1245-54.
    • (2001) Mol Cell , vol.7 , pp. 1245-1254
    • Turelli, P.1    Doucas, V.2    Craig, E.3    Mangeat, B.4    Klages, N.5    Evans, R.6
  • 61
    • 0029895410 scopus 로고    scopus 로고
    • Localization of Staf50, a member of the Ring finger family, to 11p15 by fluorescence in situ hybridization
    • Tissot C, Taviaux SA, Diriong S, Mechti N. Localization of Staf50, a member of the Ring finger family, to 11p15 by fluorescence in situ hybridization. Genomics 1996; 34:151-3.
    • (1996) Genomics , vol.34 , pp. 151-153
    • Tissot, C.1    Taviaux, S.A.2    Diriong, S.3    Mechti, N.4
  • 62
    • 0029055286 scopus 로고
    • Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentiviral Tat proteins
    • Fridell RA, Harding LS, Bogerd HP, Cullen BR. Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentiviral Tat proteins. Virology 1995; 209:347-57.
    • (1995) Virology , vol.209 , pp. 347-357
    • Fridell, R.A.1    Harding, L.S.2    Bogerd, H.P.3    Cullen, B.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.