Novel hybrids of fluconazole and furanones: Design, synthesis and antifungal activity

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 16, 2011, Pages 4873-4878

  Borate, Hanumant B ^a   Sawargave, Sangmeshwer P ^a   Chavan, Subhash P ^a   Chandavarkar, Mohan A ^b   Iyer, Ramki ^b   Tawte, Amit ^b   Rao, Deepali ^b   Deore, Jaydeep V ^a   Kudale, Ananada S ^a   Mahajan, Pankaj S ^a   Kangire, Gopinath S ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

^b FDC Ltd   (India)

Author keywords

Antifungal activity; Fluconazole; Furanones

Indexed keywords

ANTIFUNGAL AGENT; FLUCONAZOLE; FURANONE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIGER; CANDIDA; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA NEOFORMANS; CANDIDA TROPICALIS; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; FUNGAL STRAIN; FUSARIUM PROLIFERATUM; HYBRID; MOLECULE; NONHUMAN; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

ANTIFUNGAL AGENTS; CANDIDA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; FLUCONAZOLE; FURANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

CANDIDA; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA TROPICALIS;

EID: 79960905663     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.06.022     Document Type: Article

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