Carbon analogs of antifungal dioxane-triazole derivatives: Synthesis and in vitro activities

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 24, 2008, Pages 6538-6541

  Uchida, Takuya ^a   Somada, Atsushi ^a   Kagoshima, Yoshiko ^a   Konosu, Toshiyuki ^a   Oida, Sadao ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Antifungal; Grignard reaction; Triazole

Indexed keywords

DIOXANE DERIVATIVE; FLUCONAZOLE; ITRACONAZOLE; TRIAZOLE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANTIFUNGAL AGENTS; CARBON; CHEMISTRY, PHARMACEUTICAL; DIOXANES; DRUG DESIGN; EPOXY COMPOUNDS; FLUCONAZOLE; HUMANS; ITRACONAZOLE; MICROBIAL SENSITIVITY TESTS; MODELS, CHEMICAL; STEREOISOMERISM; TRIAZOLES;

ASPERGILLUS; ASPERGILLUS FUMIGATUS; CANDIDA; CANDIDA ALBICANS;

EID: 56249105447     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.055     Document Type: Article

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