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Volumn 14, Issue 4, 2011, Pages

Pharmacology of opioids in the treatment of chronic pain syndromes

Author keywords

Codeine; Dynorphins; Endorphins; Enkephalins; Fentanyl; Hydrocodone; Hydromorphone; Intractable pain; Methadone; Morphine; Narcotics; Opioid interactions; Opioid metabolism; Oxycodone; Oxymorphone; Pharmacology; Propoxyphene; Tramadol

Indexed keywords

BUPRENORPHINE; CODEINE; DELTA OPIATE RECEPTOR; FENTANYL; HYDROCODONE; HYDROMORPHONE; KAPPA OPIATE RECEPTOR; LEVORPHANOL; METHADONE; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; MU OPIATE RECEPTOR; NALBUPHINE; NARCOTIC ANALGESIC AGENT; OPIATE AGONIST; OPIATE ANTAGONIST; OXYCODONE; OXYMORPHONE; PETHIDINE; TAPENTADOL; TRAMADOL;

EID: 79960886001     PISSN: 15333159     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (101)

References (170)
  • 1
    • 84856308489 scopus 로고    scopus 로고
    • Pain medicine: Business or profession?
    • Accessed 5/20/2011
    • Schatman ME. Pain medicine: Business or profession? Medscape Neurology 2011. www.medscape.com/viewarticle/742692. Accessed 5/20/2011.
    • (2011) Medscape Neurology
    • Schatman, M.E.1
  • 2
    • 77955013068 scopus 로고    scopus 로고
    • Fibromyalgia syndrome: A discussion of the syndrome and pharmacotherapy
    • Smith HS, Barkin RL. Fibromyalgia syndrome: A discussion of the syndrome and pharmacotherapy. Am J of Therapeutics 2010;17:419-439.
    • (2010) Am J of Therapeutics , vol.17 , pp. 419-439
    • Smith, H.S.1    Barkin, R.L.2
  • 4
    • 77955014009 scopus 로고    scopus 로고
    • Incorporation of science and clinical medicine in the process of patient-specific and patient-centered, patient focused prescribing and personalize patient care
    • Barkin RL. Incorporation of science and clinical medicine in the process of patient-specific and patient-centered, patient focused prescribing and personalize patient care. Pain Med Network 2008; 23:4-9.
    • (2008) Pain Med Network , vol.23 , pp. 4-9
    • Barkin, R.L.1
  • 5
    • 0027220668 scopus 로고
    • Opioids
    • Foley KM. Opioids. Neurol Clin 1993; 11:503-522.
    • (1993) Neurol Clin , vol.11 , pp. 503-522
    • Foley, K.M.1
  • 7
    • 0023836656 scopus 로고
    • Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats
    • Di Chiara G, Imperato A. Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. J Pharmacol Exp Ther 1988; 244:1067-1080.
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 1067-1080
    • di Chiara, G.1    Imperato, A.2
  • 8
    • 0025788959 scopus 로고
    • Morphine dopamine interaction: Ventral tegmental morphine increases nucleus accumbens dopamine release
    • Leone P, Pocock D, Wise RA. Morphine dopamine interaction: Ventral tegmental morphine increases nucleus accumbens dopamine release. Pharmacol Biochem Beh 1991; 39:469-472.
    • (1991) Pharmacol Biochem Beh , vol.39 , pp. 469-472
    • Leone, P.1    Pocock, D.2    Wise, R.A.3
  • 9
    • 0021348729 scopus 로고
    • Electro physiological evidence for excitation of rat ventral tegmental area dopaminergic neurons by morphine
    • Matthews RT, German DC. Electro physiological evidence for excitation of rat ventral tegmental area dopaminergic neurons by morphine. Neuroscience 1984; 11:617-626.
    • (1984) Neuroscience , vol.11 , pp. 617-626
    • Matthews, R.T.1    German, D.C.2
  • 10
    • 0027052952 scopus 로고
    • The delta-opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterization
    • Kieffer BL, Befort K, Gaveriaux-Ruff C, Hirth CG. The delta-opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterization. Proc Natl Acad Sci USA 1992; 89:12048-12052.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 12048-12052
    • Kieffer, B.L.1    Befort, K.2    Gaveriaux-Ruff, C.3    Hirth, C.G.4
  • 11
    • 0027050144 scopus 로고
    • Identification of pro-opiomelanocortin-derived peptides in the human adrenal medulla
    • Evans CJ, Erdelyi E, Weber E, Barchas JD. Identification of pro-opiomelanocortin-derived peptides in the human adrenal medulla. Science 1992; 258:1952-1955.
    • (1992) Science , vol.258 , pp. 1952-1955
    • Evans, C.J.1    Erdelyi, E.2    Weber, E.3    Barchas, J.D.4
  • 12
    • 0028308020 scopus 로고
    • Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family
    • Chen Y, Fan Y, Liu J, Mestek A, Tian M, Kozak CA, Yu L. Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett 1994; 347:279-283.
    • (1994) FEBS Lett , vol.347 , pp. 279-283
    • Chen, Y.1    Fan, Y.2    Liu, J.3    Mestek, A.4    Tian, M.5    Kozak, C.A.6    Yu, L.7
  • 14
    • 0030011981 scopus 로고    scopus 로고
    • Immunohistochemical localization of ORL-1 in the central nervous system of the rat
    • Anton B, Fein J, To T, Li X, Silberstein L, Evans CJ. Immunohistochemical localization of ORL-1 in the central nervous system of the rat. J Comp Neurol 1996; 368:229-251.
    • (1996) J Comp Neurol , vol.368 , pp. 229-251
    • Anton, B.1    Fein, J.2    To, T.3    Li, X.4    Silberstein, L.5    Evans, C.J.6
  • 15
    • 0024432277 scopus 로고
    • Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice
    • Paul D, Bodnar RJ, Gistrak MA, Pasternak GW. Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice. Eur J Pharmacol 1989; 168:307-314.
    • (1989) Eur J Pharmacol , vol.168 , pp. 307-314
    • Paul, D.1    Bodnar, R.J.2    Gistrak, M.A.3    Pasternak, G.W.4
  • 17
    • 0027530677 scopus 로고
    • The kappa-opioid receptor: Evidence for the different subtypes
    • Wollemann M, Benyhe S, Simon J. The kappa-opioid receptor: Evidence for the different subtypes. Life Sciences 1993; 52:599-611.
    • (1993) Life Sciences , vol.52 , pp. 599-611
    • Wollemann, M.1    Benyhe, S.2    Simon, J.3
  • 19
    • 0027426780 scopus 로고
    • Mechanism of mu-opioid receptormediated presynaptic inhibition in the rat hippocampus in vitro
    • Capogna M, Gähwiler BH, Thompson SM. Mechanism of mu-opioid receptormediated presynaptic inhibition in the rat hippocampus in vitro. J Physiol 1993; 470:539-558.
    • (1993) J Physiol , vol.470 , pp. 539-558
    • Capogna, M.1    Gähwiler, B.H.2    Thompson, S.M.3
  • 20
    • 0020029284 scopus 로고
    • Opioid peptides decrease calcium-dependent action potential duration of mouse dorsal root ganglion neurons in cell culture
    • Werz MA, MacDonald RL. Opioid peptides decrease calcium-dependent action potential duration of mouse dorsal root ganglion neurons in cell culture. Brain Research 1982; 239:315-321.
    • (1982) Brain Research , vol.239 , pp. 315-321
    • Werz, M.A.1    McDonald, R.L.2
  • 21
    • 0031033471 scopus 로고    scopus 로고
    • Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro
    • Vaughan CW, Christie MJ. Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro. J Physiol 1997; 498:463-467.
    • (1997) J Physiol , vol.498 , pp. 463-467
    • Vaughan, C.W.1    Christie, M.J.2
  • 22
    • 0022468287 scopus 로고
    • Inhibitory actions of opioid compounds on calcium fluxes and neurotransmitter release from mammalian cerebral cortical slices
    • Bradford HF, Crowder JM, White EJ. Inhibitory actions of opioid compounds on calcium fluxes and neurotransmitter release from mammalian cerebral cortical slices. Br J Pharmacol 1986; 88:87-93.
    • (1986) Br J Pharmacol , vol.88 , pp. 87-93
    • Bradford, H.F.1    Crowder, J.M.2    White, E.J.3
  • 23
  • 24
    • 0021745852 scopus 로고
    • Opioid-neurotransmitter interactions: Significance in analgesia, tolerance and dependence
    • Jhamandas KH. Opioid-neurotransmitter interactions: Significance in analgesia, tolerance and dependence. Prog Neuro-Psychopharmacol Biol Psychiatr 1984; 8:565-570.
    • (1984) Prog Neuro-Psychopharmacol Biol Psychiatr , vol.8 , pp. 565-570
    • Jhamandas, K.H.1
  • 25
    • 0019312148 scopus 로고
    • Opiates and opioid peptides hyperpolarize locus coeruleus neurons in vitro
    • Pepper CM, Henderson G. Opiates and opioid peptides hyperpolarize locus coeruleus neurons in vitro. Science 1980; 209:394-395.
    • (1980) Science , vol.209 , pp. 394-395
    • Pepper, C.M.1    Henderson, G.2
  • 26
    • 0021089457 scopus 로고
    • Opioid peptides selective for mu-and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance
    • Werz MA, MacDonald RL. Opioid peptides selective for mu-and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance. Neurosci Lett 1983; 42:173-178.
    • (1983) Neurosci Lett , vol.42 , pp. 173-178
    • Werz, M.A.1    McDonald, R.L.2
  • 27
    • 0037648696 scopus 로고    scopus 로고
    • κ-Opioid receptor-mediated enhancement of the hyperpolarization-activated current (Ih) through mobilization of intracellular calcium in rat nucleus raphe magnus
    • Pan ZZ. κ-Opioid receptor-mediated enhancement of the hyperpolarization-activated current (Ih) through mobilization of intracellular calcium in rat nucleus raphe magnus. J Physiol 2003; 583:765-775.
    • (2003) J Physiol , vol.583 , pp. 765-775
    • Pan, Z.Z.1
  • 29
    • 0021278183 scopus 로고
    • Opioid peptides
    • Thompson JW. Opioid peptides. Br Med J 1984; 288:259-261.
    • (1984) Br Med J , vol.288 , pp. 259-261
    • Thompson, J.W.1
  • 33
    • 0004097987 scopus 로고    scopus 로고
    • 6th Ed. Lippincott Williams & Wilkins, Philadelphia
    • Coda BA. Clinical Anesthesia. 6th Ed. Lippincott Williams & Wilkins, Philadelphia, 2009, pp 464-497.
    • (2009) Clinical Anesthesia , pp. 464-497
    • Coda, B.A.1
  • 37
    • 0026050991 scopus 로고
    • Morphine differentially affects sensory and affective pain ratings in neurogenic and diopathic forms of pain
    • Kupers RC, Konings H, Adriaensen H, Gybels JM. Morphine differentially affects sensory and affective pain ratings in neurogenic and diopathic forms of pain. Pain 1991; 47:5-12.
    • (1991) Pain , vol.47 , pp. 5-12
    • Kupers, R.C.1    Konings, H.2    Adriaensen, H.3    Gybels, J.M.4
  • 38
    • 0023936423 scopus 로고
    • Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain
    • Aner S, Meyerson BA. Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain. Pain 1988; 33:11-23.
    • (1988) Pain , vol.33 , pp. 11-23
    • Aner, S.1    Meyerson, B.A.2
  • 40
    • 24144470762 scopus 로고    scopus 로고
    • Morphine-6-glucuronide: Actions and mechanisms
    • Kilpatrick GJ, Smith TW. Morphine-6-glucuronide: Actions and mechanisms. Med Res Rev 2005; 25:521-544.
    • (2005) Med Res Rev , vol.25 , pp. 521-544
    • Kilpatrick, G.J.1    Smith, T.W.2
  • 41
    • 33744460724 scopus 로고    scopus 로고
    • Morphine-6-glucuronide: Morphine's successor for postoperative pain relief?
    • van Dorp EL, Romberg R, Sarton E, Bovill JG, Dahan A. Morphine-6-glucuronide: Morphine's successor for postoperative pain relief? Anesth Analg 2006; 102:1789-1797.
    • (2006) Anesth Analg , vol.102 , pp. 1789-1797
    • van Dorp, E.L.1    Romberg, R.2    Sarton, E.3    Bovill, J.G.4    Dahan, A.5
  • 42
  • 46
    • 79960876797 scopus 로고    scopus 로고
    • Pharmacology of morphine metabolites
    • Janicki PK. Pharmacology of morphine metabolites. Curr Pain Headache Rep 1997; 1:264-270.
    • (1997) Curr Pain Headache Rep , vol.1 , pp. 264-270
    • Janicki, P.K.1
  • 47
    • 0029846071 scopus 로고    scopus 로고
    • Pharmacokinetics of morphine and its glucuronides after intravenous infusion of morphine and morphine-6-glucuronide in healthy volunteers
    • Lötsch J, Stockman A, Kobal G, Brune K, Waibel R, Schmidt N, Geisslinger G. Pharmacokinetics of morphine and its glucuronides after intravenous infusion of morphine and morphine-6-glucuronide in healthy volunteers. Clin Pharmacol Therapeut 1996; 60:316-325.
    • (1996) Clin Pharmacol Therapeut , vol.60 , pp. 316-325
    • Lötsch, J.1    Stockman, A.2    Kobal, G.3    Brune, K.4    Waibel, R.5    Schmidt, N.6    Geisslinger, G.7
  • 48
    • 0021262242 scopus 로고
    • Pharmacokinetics and analgesic effect of slow-release oral morphine sulphate in volunteers
    • Vater M, Smith G, Aherne GW, Aitkenhead AR. Pharmacokinetics and analgesic effect of slow-release oral morphine sulphate in volunteers. Br J Anaesth 1984; 56:821-827.
    • (1984) Br J Anaesth , vol.56 , pp. 821-827
    • Vater, M.1    Smith, G.2    Aherne, G.W.3    Aitkenhead, A.R.4
  • 49
    • 79960866336 scopus 로고    scopus 로고
    • Managing chronic moderate to severe pain-Embeda (Morphine sulfate and naltrexone hydrochloride) extended release capsules for oral use
    • Gharibo C. Managing chronic moderate to severe pain-Embeda (Morphine sulfate and naltrexone hydrochloride) extended release capsules for oral use. US Neurol 2010; 6:18-22.
    • (2010) US Neurol , vol.6 , pp. 18-22
    • Gharibo, C.1
  • 51
    • 0036357004 scopus 로고    scopus 로고
    • Hydromorphone for acute and chronic pain
    • Quigley C: Hydromorphone for acute and chronic pain. Cochrane Database Syst Rev 2002; 1:CD003447
    • (2002) Cochrane Database Syst Rev , vol.1
    • Quigley, C.1
  • 52
    • 33847769847 scopus 로고    scopus 로고
    • Pharmacokinetic profile of a 24-hour controlled-release OROS formulation of hydromorphone in the presence and absence of food
    • Sathyan G, Xu E, Thipphawong J, Gupta SK. Pharmacokinetic profile of a 24-hour controlled-release OROS formulation of hydromorphone in the presence and absence of food. BMC Clin Pharmacol 2007; 7:2-9.
    • (2007) BMC Clin Pharmacol , vol.7 , pp. 2-9
    • Sathyan, G.1    Xu, E.2    Thipphawong, J.3    Gupta, S.K.4
  • 53
    • 0036323891 scopus 로고    scopus 로고
    • Clinical pharmacology of opioids for pain
    • Inturrisi CE: Clinical pharmacology of opioids for pain. Clin J Pain 2002; 8:S3-13.
    • (2002) Clin J Pain , vol.8
    • Inturrisi, C.E.1
  • 54
    • 0035088248 scopus 로고    scopus 로고
    • Hydromorphone: Pharmacology and clinical applications in cancer patients
    • Sarhill N, Walsh D, Nelson KA. Hydromorphone: Pharmacology and clinical applications in cancer patients. Support Care Cancer 2001; 9:84-96.
    • (2001) Support Care Cancer , vol.9 , pp. 84-96
    • Sarhill, N.1    Walsh, D.2    Nelson, K.A.3
  • 55
    • 53449092404 scopus 로고    scopus 로고
    • Hydromorphone efficacy and treatment protocol impact on tolerance and mu-opioid receptor regulation
    • Kumar P, Sunkaraneni S, Sirohi S, Dighe SV, Walker EA, Yoburn BC. Hydromorphone efficacy and treatment protocol impact on tolerance and mu-opioid receptor regulation. Eur J Pharmacol 2008; 597:39-45.
    • (2008) Eur J Pharmacol , vol.597 , pp. 39-45
    • Kumar, P.1    Sunkaraneni, S.2    Sirohi, S.3    Dighe, S.V.4    Walker, E.A.5    Yoburn, B.C.6
  • 56
    • 0019500243 scopus 로고
    • Pharmacokinetics and bioavailability of hydromorphone following intravenous and oral administration to human subjects
    • Vallner JJ, Stewart JT, Kotzan JA, Kirsten EB, Honigberg IL. Pharmacokinetics and bioavailability of hydromorphone following intravenous and oral administration to human subjects. J Clin Pharmacol 1981; 21:152-156.
    • (1981) J Clin Pharmacol , vol.21 , pp. 152-156
    • Vallner, J.J.1    Stewart, J.T.2    Kotzan, J.A.3    Kirsten, E.B.4    Honigberg, I.L.5
  • 57
    • 0023720412 scopus 로고
    • Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids
    • Hennies HH, Friderichs E, Schneider J. Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids. Arzneimittelforschung 1988; 38:877-880.
    • (1988) Arzneimittelforschung , vol.38 , pp. 877-880
    • Hennies, H.H.1    Friderichs, E.2    Schneider, J.3
  • 58
    • 0035876325 scopus 로고    scopus 로고
    • Hydromophone-3-glucuronide: A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide
    • Wright AW, Mather LE, Smith MT. Hydromophone-3-glucuronide: A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sci 2001;69: 409-420.
    • (2001) Life Sci , vol.69 , pp. 409-420
    • Wright, A.W.1    Mather, L.E.2    Smith, M.T.3
  • 59
    • 34748831695 scopus 로고    scopus 로고
    • Use of oral oxymorphone in the elderly
    • Guay DR. Use of oral oxymorphone in the elderly. Consult Pharm 2007; 22:417-430.
    • (2007) Consult Pharm , vol.22 , pp. 417-430
    • Guay, D.R.1
  • 61
    • 0032605897 scopus 로고    scopus 로고
    • Pierre-Jean Robiquet
    • [French]
    • Warolin C. Pierre-Jean Robiquet. Rev Hist Pharm (Paris) 1999; 47:97-110. [French]
    • (1999) Rev Hist Pharm (Paris) , vol.47 , pp. 97-110
    • Warolin, C.1
  • 62
    • 67650736252 scopus 로고    scopus 로고
    • Opioid metabolism
    • Smith HS. Opioid metabolism. Mayo Clin Proc 2009; 84:613-624.
    • (2009) Mayo Clin Proc , vol.84 , pp. 613-624
    • Smith, H.S.1
  • 64
    • 0004134409 scopus 로고    scopus 로고
    • (ed), Australian Medicines Handbook, Adelaide
    • Rossi S, (ed). Australian Medicines Handbook. Australian Medicines Handbook, Adelaide, 2004.
    • (2004) Australian Medicines Handbook
    • Rossi, S.1
  • 66
    • 10844248488 scopus 로고    scopus 로고
    • Analgesic effects of codeine-6-glucuronide after intravenous administration
    • Srinivasan V, Wielbo D, Tebbett IR. Analgesic effects of codeine-6-glucuronide after intravenous administration. Eur J Pain 1997; 1:185-190.
    • (1997) Eur J Pain , vol.1 , pp. 185-190
    • Srinivasan, V.1    Wielbo, D.2    Tebbett, I.R.3
  • 67
    • 3242668019 scopus 로고    scopus 로고
    • Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain
    • Reynolds L, Rauck R, Webster L, DuPen S, Heinze E, Portenoy R, Katz N, Charapata S, Wallace M, Fisher DM. Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain. Pain 2004; 10:182-188.
    • (2004) Pain , vol.10 , pp. 182-188
    • Reynolds, L.1    Rauck, R.2    Webster, L.3    du Pen, S.4    Heinze, E.5    Portenoy, R.6    Katz, N.7    Charapata, S.8    Wallace, M.9    Fisher, D.M.10
  • 68
    • 0032870072 scopus 로고    scopus 로고
    • The relative potency of oral transmucosal fentanyl citrate compared with intravenous morphine in the treatment of moderate to severe postoperative pain
    • Lichtor JL, Sevarino FB, Joshi GP, Busch MA, Nordbrock E, Ginsberg B. The relative potency of oral transmucosal fentanyl citrate compared with intravenous morphine in the treatment of moderate to severe postoperative pain. Anesth Analg 1999; 89:732-738.
    • (1999) Anesth Analg , vol.89 , pp. 732-738
    • Lichtor, J.L.1    Sevarino, F.B.2    Joshi, G.P.3    Busch, M.A.4    Nordbrock, E.5    Ginsberg, B.6
  • 69
    • 78650730742 scopus 로고    scopus 로고
    • Transport mechanisms in oral transmucosal drug delivery: Implications for pain management
    • Kim KS, Simon L. Transport mechanisms in oral transmucosal drug delivery: Implications for pain management. Math Biosci 2011; 229:93-100.
    • (2011) Math Biosci , vol.229 , pp. 93-100
    • Kim, K.S.1    Simon, L.2
  • 70
    • 77953741203 scopus 로고    scopus 로고
    • Evaluation of the single-and multipledose pharmacokinetics of fentanyl buccal soluble film in normal healthy volunteers
    • Vasisht N, Gever LN, Tagarro I, Finn AL. Evaluation of the single-and multipledose pharmacokinetics of fentanyl buccal soluble film in normal healthy volunteers. J Clin Pharmacol 2010; 50:785-791.
    • (2010) J Clin Pharmacol , vol.50 , pp. 785-791
    • Vasisht, N.1    Gever, L.N.2    Tagarro, I.3    Finn, A.L.4
  • 71
    • 73349103141 scopus 로고    scopus 로고
    • Formulations of fentanyl in the management of pain
    • Grape S, Schug SA, Lauer S, Schug BS. Formulations of fentanyl in the management of pain. Drugs 2010; 70:57-72.
    • (2010) Drugs , vol.70 , pp. 57-72
    • Grape, S.1    Schug, S.A.2    Lauer, S.3    Schug, B.S.4
  • 72
    • 75349092325 scopus 로고    scopus 로고
    • Transdermal fentanyl: Pharmacology and toxicology
    • Nelson L, Schwaner R. Transdermal fentanyl: Pharmacology and toxicology. J Med Toxicol 2009; 5:230-241.
    • (2009) J Med Toxicol , vol.5 , pp. 230-241
    • Nelson, L.1    Schwaner, R.2
  • 73
    • 0031018574 scopus 로고    scopus 로고
    • Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control
    • Jeal W, Benfield P. Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control. Drugs 1997; 53:109-138.
    • (1997) Drugs , vol.53 , pp. 109-138
    • Jeal, W.1    Benfield, P.2
  • 74
    • 7044245703 scopus 로고    scopus 로고
    • Opioids in renal failure and dialysis patients
    • Dean M. Opioids in renal failure and dialysis patients. J Pain Symptom Manage 2004; 28:497-504.
    • (2004) J Pain Symptom Manage , vol.28 , pp. 497-504
    • Dean, M.1
  • 76
    • 33847139761 scopus 로고    scopus 로고
    • Levorphanol: The forgotten opioid
    • Prommer E. Levorphanol: The forgotten opioid. Support Care Cancer 2007; 15:259-264.
    • (2007) Support Care Cancer , vol.15 , pp. 259-264
    • Prommer, E.1
  • 77
    • 0347991961 scopus 로고    scopus 로고
    • 10-Ketormorphinan and 3-substituted-3-desoxymorphian analogues as mixed kappa and micro opioid ligands: Synthesis and biological evaluation of their binding aflinity at opioid receptors
    • Zhang A, Xiong W, Bidlack JM, Hilbert JE, Knapp BI. Wentland MP, Neumeyer JL. 10-Ketormorphinan and 3-substituted-3-desoxymorphian analogues as mixed kappa and micro opioid ligands: Synthesis and biological evaluation of their binding aflinity at opioid receptors. J Med Chem 2004; 47:165-174.
    • (2004) J Med Chem , vol.47 , pp. 165-174
    • Zhang, A.1    Xiong, W.2    Bidlack, J.M.3    Hilbert, J.E.4    Knapp, B.I.5    Wentland, M.P.6    Neumeyer, J.L.7
  • 78
    • 0345167178 scopus 로고    scopus 로고
    • Differential effects of agonists on adenylyl cyclase superactivation mediated by the kappa opioid receptors: Adenylyl cyclase superactivatian is independent of agonist-induced phosphorylation, desensitization, internalization, and down-regulation
    • Wang Y, Li JG. Huang P, Xu W, Liu-Chen LY. Differential effects of agonists on adenylyl cyclase superactivation mediated by the kappa opioid receptors: Adenylyl cyclase superactivatian is independent of agonist-induced phosphorylation, desensitization, internalization, and down-regulation. J Pharmacol Exp Ther 2003; 307:1127-1134.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 1127-1134
    • Wang, Y.1    Li, J.G.2    Huang, P.3    Xu, W.4    Liu-Chen, L.Y.5
  • 80
    • 0023892622 scopus 로고
    • Unidirectional analgesic cross-tolerance between morphine and levorphanol in the rat
    • Moulin DE, Ling GS, Pasternak GW. Unidirectional analgesic cross-tolerance between morphine and levorphanol in the rat. Pain 1988;33:233-239.
    • (1988) Pain , vol.33 , pp. 233-239
    • Moulin, D.E.1    Ling, G.S.2    Pasternak, G.W.3
  • 81
    • 0030946553 scopus 로고    scopus 로고
    • Differential agonist regulation of the human kappa-opioid receptor
    • Blake AD, Bat G, Li S, Freeman JC, Reisine T. Differential agonist regulation of the human kappa-opioid receptor. J Neurochem 1997; 68:1846-1852.
    • (1997) J Neurochem , vol.68 , pp. 1846-1852
    • Blake, A.D.1    Bat, G.2    Li, S.3    Freeman, J.C.4    Reisine, T.5
  • 82
    • 0034569462 scopus 로고    scopus 로고
    • D-morphine, but not L-morphine, has low micromolar affinity for the noncompetitive N-methyl-D-aspartate site in rat forebrain. Possible clinical implications for the management of neuropathic pain
    • Stringer M, Makin MK, Miles J, Morley JS. D-morphine, but not L-morphine, has low micromolar affinity for the noncompetitive N-methyl-D-aspartate site in rat forebrain. Possible clinical implications for the management of neuropathic pain. Neurosci Lett 2000; 295:21-24.
    • (2000) Neurosci Lett , vol.295 , pp. 21-24
    • Stringer, M.1    Makin, M.K.2    Miles, J.3    Morley, J.S.4
  • 83
    • 34248342143 scopus 로고    scopus 로고
    • Can levorphanol be used like methadone for intractable refractory pain?
    • McNulty JP. Can levorphanol be used like methadone for intractable refractory pain? J Palliat Med 2007; 10:293-296.
    • (2007) J Palliat Med , vol.10 , pp. 293-296
    • McNulty, J.P.1
  • 84
    • 0018367544 scopus 로고
    • Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity
    • Labella FS, Pinsky C, Havlicek V. Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity. Brain Res 1979; 174:263-271.
    • (1979) Brain Res , vol.174 , pp. 263-271
    • Labella, F.S.1    Pinsky, C.2    Havlicek, V.3
  • 86
    • 0030883482 scopus 로고    scopus 로고
    • Meperidine-induced generalized seizures with normal renal function
    • Marinella MA. Meperidine-induced generalized seizures with normal renal function. South Med J 1997; 90:556-558.
    • (1997) South Med J , vol.90 , pp. 556-558
    • Marinella, M.A.1
  • 87
    • 66749123070 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions of synthetic opiate analgesics
    • Armstrong SC, Wynn GH, Sandson NB. Pharmacokinetic drug interactions of synthetic opiate analgesics. Psychosomatics 2009; 50:169-176.
    • (2009) Psychosomatics , vol.50 , pp. 169-176
    • Armstrong, S.C.1    Wynn, G.H.2    Sandson, N.B.3
  • 88
    • 79960856969 scopus 로고    scopus 로고
    • The serotonin syndrome. Implicated drugs, pathophysiology and management
    • Sporer KA. The serotonin syndrome. Implicated drugs, pathophysiology and management. Drug Saf 1996; 15:8-29.
    • (1996) Drug Saf , vol.15 , pp. 8-29
    • Sporer, K.A.1
  • 89
    • 26444511151 scopus 로고    scopus 로고
    • Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity
    • Gillman PK. Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. Br J Anaesth 2005; 95:434-441.
    • (2005) Br J Anaesth , vol.95 , pp. 434-441
    • Gillman, P.K.1
  • 90
    • 2942584907 scopus 로고    scopus 로고
    • Meperidine is alive and well in the new millennium: Evaluation of meperidine usage patterns and frequency of adverse drug reactions
    • Seifert CF, Kennedy S. Meperidine is alive and well in the new millennium: Evaluation of meperidine usage patterns and frequency of adverse drug reactions. Pharmacotherapy 2004; 24:776-783.
    • (2004) Pharmacotherapy , vol.24 , pp. 776-783
    • Seifert, C.F.1    Kennedy, S.2
  • 95
    • 0017073234 scopus 로고
    • The clinical pharmacology of meperidine-comparison of routes of administration
    • Stambaugh JE, Wainer IW, Sanstead JK, Hemphill DM. The clinical pharmacology of meperidine-comparison of routes of administration. J Clin Pharmacol 1976; 16:245-256.
    • (1976) J Clin Pharmacol , vol.16 , pp. 245-256
    • Stambaugh, J.E.1    Wainer, I.W.2    Sanstead, J.K.3    Hemphill, D.M.4
  • 96
    • 66149165776 scopus 로고    scopus 로고
    • Methadone-associated Q-T interval prolongation and torsades de pointes
    • Stringer J, Welsh C, Tommasello A. Methadone-associated Q-T interval prolongation and torsades de pointes. Am J Health Syst Pharm 2009; 66:825-833.
    • (2009) Am J Health Syst Pharm , vol.66 , pp. 825-833
    • Stringer, J.1    Welsh, C.2    Tommasello, A.3
  • 97
    • 79959991691 scopus 로고    scopus 로고
    • QT interval prolongation:Prevalence, risk factors and pharmacovigilance data among methadone-treated patients in France
    • Perrin-Terrin A, Pathak A, Lapeyre-Mestre M. QT interval prolongation:Prevalence, risk factors and pharmacovigilance data among methadone-treated patients in France. Fundam Clin Pharmacol 2011; 25:503-510.
    • (2011) Fundam Clin Pharmacol , vol.25 , pp. 503-510
    • Perrin-Terrin, A.1    Pathak, A.2    Lapeyre-Mestre, M.3
  • 98
    • 77954444634 scopus 로고    scopus 로고
    • The effect of oral methadone on the QTc interval in advanced cancer patients: A prospective pilot study
    • Heppe DB, Haigney MC, Kranz MJ. The effect of oral methadone on the QTc interval in advanced cancer patients: A prospective pilot study. J Palliat Med 2010; 13:638-639.
    • (2010) J Palliat Med , vol.13 , pp. 638-639
    • Heppe, D.B.1    Haigney, M.C.2    Kranz, M.J.3
  • 99
    • 77953379085 scopus 로고    scopus 로고
    • Retrospective analysis of low-dose methadone and QTc prolongation in chronic pain patients
    • Huh B, Park CH. Retrospective analysis of low-dose methadone and QTc prolongation in chronic pain patients. Korean J Anesthesiol 2010; 58:338-343.
    • (2010) Korean J Anesthesiol , vol.58 , pp. 338-343
    • Huh, B.1    Park, C.H.2
  • 102
    • 34249338680 scopus 로고    scopus 로고
    • Long term methadone for chronic pain: A pilot study of pharmacokinetic aspects
    • Fredheim OM, Borchgrevink PC, Klepstad P, Kaasa S, Dale O. Long term methadone for chronic pain: A pilot study of pharmacokinetic aspects. Eur J Pain 2007; 11:599-604.
    • (2007) Eur J Pain , vol.11 , pp. 599-604
    • Fredheim, O.M.1    Borchgrevink, P.C.2    Klepstad, P.3    Kaasa, S.4    Dale, O.5
  • 104
    • 0034741112 scopus 로고    scopus 로고
    • Blockade of rat alpha3beta4 nicotinic receptor function by methadone, its metabolites, and structural analogs
    • Xiao Y, Smith RD, Caruso FS, Kellar KJ. Blockade of rat alpha3beta4 nicotinic receptor function by methadone, its metabolites, and structural analogs. J Pharmacol Exp Ther 2001; 299:366-371.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 366-371
    • Xiao, Y.1    Smith, R.D.2    Caruso, F.S.3    Kellar, K.J.4
  • 105
    • 48249112969 scopus 로고    scopus 로고
    • Opioids and the management of chronic severe pain in the elderly: Consensus statement of an international expert panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone)
    • Pergolizzi J, Böger RH, Budd K, Dahan A, Erdine S, Hans G, Kress HG, Langford R, Likar R, Raffa RB, Sacerdote P. Opioids and the management of chronic severe pain in the elderly: Consensus statement of an international expert panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone). Pain Pract 2008; 8:287-313.
    • (2008) Pain Pract , vol.8 , pp. 287-313
    • Pergolizzi, J.1    Böger, R.H.2    Budd, K.3    Dahan, A.4    Erdine, S.5    Hans, G.6    Kress, H.G.7    Langford, R.8    Likar, R.9    Raffa, R.B.10    Sacerdote, P.11
  • 106
    • 48449090970 scopus 로고    scopus 로고
    • A systematic review of opioid conversion ratios used with methadone for the treatment of pain
    • Weschules DJ, Bain KT. A systematic review of opioid conversion ratios used with methadone for the treatment of pain. Pain Med 2008; 9:595-612.
    • (2008) Pain Med , vol.9 , pp. 595-612
    • Weschules, D.J.1    Bain, K.T.2
  • 107
    • 0025609208 scopus 로고
    • The correlation between predicted and measured patient specific analgesic concentrations after intravenous titration: A guide for initial maintenance requirements with methadone
    • Denson DD, Concilus RR, Gregg RV, Crews JC. The correlation between predicted and measured patient specific analgesic concentrations after intravenous titration: A guide for initial maintenance requirements with methadone. J Clin Pharmacol 1990; 30:1049-1054.
    • (1990) J Clin Pharmacol , vol.30 , pp. 1049-1054
    • Denson, D.D.1    Concilus, R.R.2    Gregg, R.V.3    Crews, J.C.4
  • 108
    • 68249125119 scopus 로고    scopus 로고
    • Increases in poisoning and methadone-related deaths: United States, 1999-2005
    • February, Accessed 02/14/2011
    • Fingerhut LA. Increases in poisoning and methadone-related deaths: United States, 1999-2005. NCHS Heath & Stats February 2008. http://cdc.gove/nchs/data/hestat/poisoning/poisoning.pdf. Accessed 02/14/2011.
    • (2008) NCHS Heath & Stats
    • Fingerhut, L.A.1
  • 109
    • 0002372501 scopus 로고    scopus 로고
    • Methadone: History and recommendations for use in analgesia
    • Accessed 01/29/2011
    • Gouldin WM, Kennedy DT, Small RE. Methadone: History and recommendations for use in analgesia. APS Bulletin 2000; 10:1-11www.ampainsoc.org/pub/bulletin/sep00/upda1.htm. Accessed 01/29/2011.
    • (2000) APS Bulletin , vol.10 , pp. 1-11
    • Gouldin, W.M.1    Kennedy, D.T.2    Small, R.E.3
  • 110
    • 0018142043 scopus 로고
    • Comparative metabolism of hydrocodone in man, rat, guinea pig, rabbit, and dog
    • Cone E, Darwin W, Gorodetzky C, Tan T. Comparative metabolism of hydrocodone in man, rat, guinea pig, rabbit, and dog. Drug Metab Dispos 1978; 6:488-493.
    • (1978) Drug Metab Dispos , vol.6 , pp. 488-493
    • Cone, E.1    Darwin, W.2    Gorodetzky, C.3    Tan, T.4
  • 111
    • 0025830147 scopus 로고
    • Mu receptor binding of some commonly used opioids and their metabolites
    • Chen ZR, Irvine RJ, Somogyi AA, Bochner F. Mu receptor binding of some commonly used opioids and their metabolites. Life Sci 1991; 48:2165-2171.
    • (1991) Life Sci , vol.48 , pp. 2165-2171
    • Chen, Z.R.1    Irvine, R.J.2    Somogyi, A.A.3    Bochner, F.4
  • 113
    • 1542359666 scopus 로고    scopus 로고
    • CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes
    • Hutchinson MR, Menelaou A, Foster DJR, Coller JK, Somogyi AA. CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes. Br J Clin Pharmacol 2003; 57:287-297.
    • (2003) Br J Clin Pharmacol , vol.57 , pp. 287-297
    • Hutchinson, M.R.1    Menelaou, A.2    Foster, D.J.R.3    Coller, J.K.4    Somogyi, A.A.5
  • 115
    • 0028997955 scopus 로고
    • "It's the genes, stupid. " Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism
    • Kroemer HK, Eichelbaum M. "It's the genes, stupid. " Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism. Life Sci 1995; 56:2285-2298.
    • (1995) Life Sci , vol.56 , pp. 2285-2298
    • Kroemer, H.K.1    Eichelbaum, M.2
  • 116
    • 33646183072 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites
    • Lalovic B, Kharasch E, Hoffer C, Risler L, Liu-Chen LY, Shen DD. Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites. Clin Pharmacol Ther 2006; 79:461-479.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 461-479
    • Lalovic, B.1    Kharasch, E.2    Hoffer, C.3    Risler, L.4    Liu-Chen, L.Y.5    Shen, D.D.6
  • 118
    • 0027450550 scopus 로고
    • A review of oxycodone's clinical pharmacokinetics and pharmacodynamics
    • Pöyhiä R, Vainio A, Kalso E. A review of oxycodone's clinical pharmacokinetics and pharmacodynamics. J Pain Symptom Manage 1993; 8:63-67.
    • (1993) J Pain Symptom Manage , vol.8 , pp. 63-67
    • Pöyhiä, R.1    Vainio, A.2    Kalso, E.3
  • 119
    • 0038412561 scopus 로고    scopus 로고
    • Normal-release and controlled-release oxycodone: Pharmacokinetics, pharmacodynamics and controversy
    • Davis MP, Varga J, Dickerson D, Walsh D, LeGrand SB, Lagman R. Normal-release and controlled-release oxycodone: Pharmacokinetics, pharmacodynamics and controversy. Support Care Cancer 2003; 11:84-92.
    • (2003) Support Care Cancer , vol.11 , pp. 84-92
    • Davis, M.P.1    Varga, J.2    Dickerson, D.3    Walsh, D.4    le Grand, S.B.5    Lagman, R.6
  • 120
    • 0029040497 scopus 로고
    • The effect of intrinsic efficacy on opioid tolerance
    • Duttaroy A, Yoburn BC. The effect of intrinsic efficacy on opioid tolerance. Anesthesiology 1995; 82:1226-1236.
    • (1995) Anesthesiology , vol.82 , pp. 1226-1236
    • Duttaroy, A.1    Yoburn, B.C.2
  • 121
    • 35748979718 scopus 로고    scopus 로고
    • Oxycodone and morphine have distinctly different pharmacological profiles: Radioligand binding and behavioural studies in two rat models of neuropathic pain
    • Nielsen CK, Ross FB, Lotfipour S, Saini KS, Edwards SR, Smith MT. Oxycodone and morphine have distinctly different pharmacological profiles: Radioligand binding and behavioural studies in two rat models of neuropathic pain. Pain 2007; 132:289-300.
    • (2007) Pain , vol.132 , pp. 289-300
    • Nielsen, C.K.1    Ross, F.B.2    Lotfipour, S.3    Saini, K.S.4    Edwards, S.R.5    Smith, M.T.6
  • 122
    • 0030781043 scopus 로고    scopus 로고
    • The intrinsic antinociceptive effects of oxycodone appear to be kappa-opioid receptor mediated
    • Ross FB, Smith MT. The intrinsic antinociceptive effects of oxycodone appear to be kappa-opioid receptor mediated. Pain 1997; 73:151-157.
    • (1997) Pain , vol.73 , pp. 151-157
    • Ross, F.B.1    Smith, M.T.2
  • 124
    • 77954560524 scopus 로고    scopus 로고
    • Two-sept iron(0)-mediated N-demethylation of N-methyl alkaloids
    • Kok GB, Pye CC, Singer RD, Scammells PJ. Two-sept iron(0)-mediated N-demethylation of N-methyl alkaloids. J Org Chem 2010; 75:4806-4811.
    • (2010) J Org Chem , vol.75 , pp. 4806-4811
    • Kok, G.B.1    Pye, C.C.2    Singer, R.D.3    Scammells, P.J.4
  • 125
    • 52949145614 scopus 로고    scopus 로고
    • Review of oral oxymorphone in the management of pain
    • Sloan P. Review of oral oxymorphone in the management of pain. Therapeut Clin Risk Manage 2008; 4:777-787.
    • (2008) Therapeut Clin Risk Manage , vol.4 , pp. 777-787
    • Sloan, P.1
  • 126
    • 0024549904 scopus 로고
    • A comparison of morphine, meperidine, and oxymorphone as utilized in patientcontrolled analgesia following cesarean delivery
    • Sinatra RS, Lodge K, Sibert K, Chung KS, Chung JH, Parker A Jr, Harrison DM. A comparison of morphine, meperidine, and oxymorphone as utilized in patientcontrolled analgesia following cesarean delivery. Anesthesiology 1989; 70:585-590.
    • (1989) Anesthesiology , vol.70 , pp. 585-590
    • Sinatra, R.S.1    Lodge, K.2    Sibert, K.3    Chung, K.S.4    Chung, J.H.5    Parker Jr., A.6    Harrison, D.M.7
  • 127
    • 13244272132 scopus 로고    scopus 로고
    • Effectiveness and safety of oral extended-release oxymorphone for the treatment of cancer pain: A pilot study
    • Sloan PA, Slatkin NE, Ahdieh H. Effectiveness and safety of oral extended-release oxymorphone for the treatment of cancer pain: A pilot study. Supp Care Cancer 2005; 13:57-65.
    • (2005) Supp Care Cancer , vol.13 , pp. 57-65
    • Sloan, P.A.1    Slatkin, N.E.2    Ahdieh, H.3
  • 128
    • 16844373756 scopus 로고    scopus 로고
    • Single-and multiple-dose pharmacokinetic and doseproportionality study of oxymorphone immediate-release tablets
    • Adams MP, Ahdieh H. Single-and multiple-dose pharmacokinetic and doseproportionality study of oxymorphone immediate-release tablets. Drugs R D 2005; 6:91-99.
    • (2005) Drugs R D , vol.6 , pp. 91-99
    • Adams, M.P.1    Ahdieh, H.2
  • 129
    • 6444221477 scopus 로고    scopus 로고
    • The efficacy and safety of oral immediate-release oxymorphone for postsurgical pain
    • Gimbel J, Ahdieh H. The efficacy and safety of oral immediate-release oxymorphone for postsurgical pain. Anesth Analg 2004; 99:1472-1477.
    • (2004) Anesth Analg , vol.99 , pp. 1472-1477
    • Gimbel, J.1    Ahdieh, H.2
  • 130
    • 79955034777 scopus 로고    scopus 로고
    • Oral oxymorphone extendedrelease
    • Guay DR. Oral oxymorphone extendedrelease. Consult Pharm 2010; 25:816-828.
    • (2010) Consult Pharm , vol.25 , pp. 816-828
    • Guay, D.R.1
  • 131
    • 34447521417 scopus 로고    scopus 로고
    • Oral extended-release oxymorphone: A new choice for chronic pain relief
    • Matsumoto AK. Oral extended-release oxymorphone: A new choice for chronic pain relief. Expert Opin Pharmacother 2007; 8:1515-1527.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 1515-1527
    • Matsumoto, A.K.1
  • 132
    • 16844377997 scopus 로고    scopus 로고
    • Oxymorphone extended release does not affect CYP2C9 or CYP3A4 metabolic pathways
    • Adams M, Pieniaszek HJ Jr, Gammaitoni AR, Ahdieh H. Oxymorphone extended release does not affect CYP2C9 or CYP3A4 metabolic pathways. J Clin Pharmacol 2005; 45:337-345.
    • (2005) J Clin Pharmacol , vol.45 , pp. 337-345
    • Adams, M.1    Pieniaszek Jr., H.J.2    Gammaitoni, A.R.3    Ahdieh, H.4
  • 133
    • 48449091303 scopus 로고    scopus 로고
    • Oxymorphone and oxymorphone extended release: A pharmacotherapeutic review
    • Sloan PA, Barkin RL. Oxymorphone and oxymorphone extended release: A pharmacotherapeutic review. J Opioid Manage 2008; 4:3131-144.
    • (2008) J Opioid Manage , vol.4 , pp. 3131-3144
    • Sloan, P.A.1    Barkin, R.L.2
  • 134
    • 79551701899 scopus 로고    scopus 로고
    • The efficacy of intravenous paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children
    • Uysal HY, Takmaz SA, Yaman F, Baltaci B, Baar H. The efficacy of intravenous paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children. J Clin Anesth 2011; 23:53-57.
    • (2011) J Clin Anesth , vol.23 , pp. 53-57
    • Uysal, H.Y.1    Takmaz, S.A.2    Yaman, F.3    Baltaci, B.4    Baar, H.5
  • 135
    • 68349128590 scopus 로고    scopus 로고
    • Tramadol: Seizures, serotonin syndrome, and coadministered antidepressants
    • Sansone RA, Sansone LA. Tramadol: Seizures, serotonin syndrome, and coadministered antidepressants. Psychiatry (Edgmont) 2009; 6:17-21.
    • (2009) Psychiatry (Edgmont) , vol.6 , pp. 17-21
    • Sansone, R.A.1    Sansone, L.A.2
  • 137
    • 45949106393 scopus 로고    scopus 로고
    • Dilemmas in chronic/persistent pain management
    • Katz W, Barkin RL. Dilemmas in chronic/persistent pain management. Am J Ther 2008; 15:256-264.
    • (2008) Am J Ther , vol.15 , pp. 256-264
    • Katz, W.1    Barkin, R.L.2
  • 138
    • 41349099452 scopus 로고    scopus 로고
    • Extended-release tramadol (ULTRAM®ER): A pharmacotherapeutic, pharmacokinetic, and pharmacodynamic focus on effectiveness and safety in patients with chronic/persistent pain
    • Barkin RL. Extended-release tramadol (ULTRAM®ER): A pharmacotherapeutic, pharmacokinetic, and pharmacodynamic focus on effectiveness and safety in patients with chronic/persistent pain. Am J Ther 2008; 15:157-166.
    • (2008) Am J Ther , vol.15 , pp. 157-166
    • Barkin, R.L.1
  • 139
    • 74549207680 scopus 로고    scopus 로고
    • Tapentadol hydrochloride: A centrally acting oral analgesic
    • Wade WE, Spruill WJ. Tapentadol hydrochloride: A centrally acting oral analgesic. Clin Ther 2009; 31:2804-2818.
    • (2009) Clin Ther , vol.31 , pp. 2804-2818
    • Wade, W.E.1    Spruill, W.J.2
  • 140
    • 77955012571 scopus 로고    scopus 로고
    • Tapentadol: A pharmacotherapeutic focused brief review
    • Barkin RL. Tapentadol: A pharmacotherapeutic focused brief review. Pain Med Network 2009; 24:8,11.
    • (2009) Pain Med Network , vol.24
    • Barkin, R.L.1
  • 144
    • 33751079623 scopus 로고    scopus 로고
    • One-year mortality rates of patients receiving methadone and buprenorphine maintenance therapy: A nationally representative cohort study in 2694 patients
    • Soyka M, Apelt SM, Lieb M, Wittchen HU. One-year mortality rates of patients receiving methadone and buprenorphine maintenance therapy: A nationally representative cohort study in 2694 patients. J Clin Psychopharmacol 2006; 26:657-660.
    • (2006) J Clin Psychopharmacol , vol.26 , pp. 657-660
    • Soyka, M.1    Apelt, S.M.2    Lieb, M.3    Wittchen, H.U.4
  • 145
    • 0017064976 scopus 로고
    • The effects of morphine-and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog
    • Martin WR, Eades CG, Thompson JA, Huppler RE, Gilbert PE. The effects of morphine-and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther 1976; 197:517-532.
    • (1976) J Pharmacol Exp Ther , vol.197 , pp. 517-532
    • Martin, W.R.1    Eades, C.G.2    Thompson, J.A.3    Huppler, R.E.4    Gilbert, P.E.5
  • 146
    • 4644245300 scopus 로고    scopus 로고
    • Buprenorphine: A unique drug with complex pharmacology
    • Lutfy K, Cowan A. Buprenorphine: A unique drug with complex pharmacology. Curr Neuropharmacol 2004; 2:395-402.
    • (2004) Curr Neuropharmacol , vol.2 , pp. 395-402
    • Lutfy, K.1    Cowan, A.2
  • 148
    • 0020510522 scopus 로고
    • Clinical pharmacokinetics of narcotic agonist-antagonist drugs
    • Bullingham RE, McQuay HJ, Moore RA. Clinical pharmacokinetics of narcotic agonist-antagonist drugs. Clin Pharmacokinet 1983; 8:332-343.
    • (1983) Clin Pharmacokinet , vol.8 , pp. 332-343
    • Bullingham, R.E.1    McQuay, H.J.2    Moore, R.A.3
  • 149
  • 151
    • 0020062643 scopus 로고
    • Single-dose comparison of buprenorphine 0.3 and 0.6mg i.v. given after operation: Clinical effects and plasma concentration
    • Watson PJQ, McQuay HJ, Bullingham RE, Allen MC, Moore RA. Single-dose comparison of buprenorphine 0.3 and 0.6mg i.v. given after operation: Clinical effects and plasma concentration. Br J Anaesth 1982; 54:37-43.
    • (1982) Br J Anaesth , vol.54 , pp. 37-43
    • Watson, P.J.Q.1    McQuay, H.J.2    Bullingham, R.E.3    Allen, M.C.4    Moore, R.A.5
  • 152
    • 0000226802 scopus 로고
    • Absorption, distribution, metabolism, and excretion of buprenorphine in animals and humans
    • Wiley-Liss, New York, In: Cowan A, Lewis JW (eds)
    • Walter DS, Inturrisi CE. Absorption, distribution, metabolism, and excretion of buprenorphine in animals and humans. In: Cowan A, Lewis JW (eds). Buprenorphine: Combatting Drug Abuse with a Unique Opioid. Wiley-Liss, New York, 1995, pp 113-135.
    • (1995) Buprenorphine: Combatting Drug Abuse with a Unique Opioid , pp. 113-135
    • Walter, D.S.1    Inturrisi, C.E.2
  • 153
    • 0030943931 scopus 로고    scopus 로고
    • Involvement of cytochrome P450 3A4 in n-dealkylation of buprenorphine in human liver microsomes
    • Iribarne C, Picart D, Dreano Y, Bail JP, Berthou F. Involvement of cytochrome P450 3A4 in n-dealkylation of buprenorphine in human liver microsomes. Life Sci 1997; 60:1953-1964.
    • (1997) Life Sci , vol.60 , pp. 1953-1964
    • Iribarne, C.1    Picart, D.2    Dreano, Y.3    Bail, J.P.4    Berthou, F.5
  • 156
    • 0031465148 scopus 로고    scopus 로고
    • Subnanogram-concentration measurement of buprenorphine in human plasma by electron-capture capillary gas chromatography: Application to pharmacokinetics of sublingual buprenorphine
    • Everhart ET, Cheung P, Shwonek P, Zabel K, Tisdale EC, Jacob P, Mendelson J, Jones RT. Subnanogram-concentration measurement of buprenorphine in human plasma by electron-capture capillary gas chromatography: Application to pharmacokinetics of sublingual buprenorphine. Clin Chem 1997; 43:2292-2302.
    • (1997) Clin Chem , vol.43 , pp. 2292-2302
    • Everhart, E.T.1    Cheung, P.2    Shwonek, P.3    Zabel, K.4    Tisdale, E.C.5    Jacob, P.6    Mendelson, J.7    Jones, R.T.8
  • 157
    • 0019418122 scopus 로고
    • Sublingual buprenorphine used postoperatively: Clinical observations and preliminary pharmacokinetic analysis
    • Bullingham RE, McQuay HJ, Dwyer D, Allen MC, Moore RA. Sublingual buprenorphine used postoperatively: Clinical observations and preliminary pharmacokinetic analysis. Br J Clin Pharmacol 1981; 12:117-122.
    • (1981) Br J Clin Pharmacol , vol.12 , pp. 117-122
    • Bullingham, R.E.1    McQuay, H.J.2    Dwyer, D.3    Allen, M.C.4    Moore, R.A.5
  • 161
    • 26844568733 scopus 로고    scopus 로고
    • Sublingual buprenorphine is effective in the treatment of chronic pain syndrome
    • Malinoff HL, Barkin RL, Wilson G. Sublingual buprenorphine is effective in the treatment of chronic pain syndrome. Am J Ther 2005; 12:379-384.
    • (2005) Am J Ther , vol.12 , pp. 379-384
    • Malinoff, H.L.1    Barkin, R.L.2    Wilson, G.3
  • 162
    • 0027452629 scopus 로고
    • The opioid receptor binding of dezocine, morphine, fentanyl, butorphanol, and nalbuphine
    • Chen JC, Smith ER, Cahill M, Cohen R, Fishman JB. The opioid receptor binding of dezocine, morphine, fentanyl, butorphanol, and nalbuphine. Life Sci 1993; 52:389-396.
    • (1993) Life Sci , vol.52 , pp. 389-396
    • Chen, J.C.1    Smith, E.R.2    Cahill, M.3    Cohen, R.4    Fishman, J.B.5
  • 164
    • 0023882279 scopus 로고
    • Nalbuphine: An autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic
    • DeSouza EB, Schmidt WK, Kuhar MJ. Nalbuphine: An autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic. J Pharmacol Exp Ther 1988; 244:391-402.
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 391-402
    • DeSouza, E.B.1    Schmidt, W.K.2    Kuhar, M.J.3
  • 165
    • 2342577496 scopus 로고    scopus 로고
    • Use of the mixed agonist-antagonist nalbuphine in opioid based analgesia
    • Gunion MW, Marchionne AM, Anderson CTM. Use of the mixed agonist-antagonist nalbuphine in opioid based analgesia. Acute Pain 2004; 6:29-39.
    • (2004) Acute Pain , vol.6 , pp. 29-39
    • Gunion, M.W.1    Marchionne, A.M.2    Anderson, C.T.M.3
  • 166
    • 0018187687 scopus 로고
    • A comparison of the analgesic effect of intramuscular nalbuphine and morphine in patients with postoperative pain
    • Beaver WT, Feise GA. A comparison of the analgesic effect of intramuscular nalbuphine and morphine in patients with postoperative pain. J Pharmacol Exp Ther 1978; 204:487-496.
    • (1978) J Pharmacol Exp Ther , vol.204 , pp. 487-496
    • Beaver, W.T.1    Feise, G.A.2
  • 167
    • 0020613839 scopus 로고
    • Nalbuphine. A preliminary review of its pharmacological properties and therapeutic efficacy
    • Errick JK, Heel RC. Nalbuphine. A preliminary review of its pharmacological properties and therapeutic efficacy. Drugs 1983; 26:191-211.
    • (1983) Drugs , vol.26 , pp. 191-211
    • Errick, J.K.1    Heel, R.C.2
  • 168
    • 0023475305 scopus 로고
    • The pharmacokinetics of intravenous, intramuscular, and subcutaneous nalbuphine in healthy subjects
    • Lo MW, Lee FH, Schary WL, Whitney CC. The pharmacokinetics of intravenous, intramuscular, and subcutaneous nalbuphine in healthy subjects. Eur J Clin Pharmacol 1987; 33:297-301.
    • (1987) Eur J Clin Pharmacol , vol.33 , pp. 297-301
    • Lo, M.W.1    Lee, F.H.2    Schary, W.L.3    Whitney, C.C.4


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