Synthesis and biological evaluation of meperidine analogues at monoamine transporters

Journal of Medicinal Chemistry

Volumn 48, Issue 5, 2005, Pages 1336-1343

  Lomenzo, Stacey A ^a   Rhoden, Jill B ^a   Izenwasser, Sari ^b   Wade, Dean ^b   Kopajtic, Theresa ^c   Katz, Jonathan L ^c   Trudell, Mark L ^a  

^a UNIVERSITY OF NEW ORLEANS   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 NAPHTHALEN 2 YLPIPERIDINE 4 CARBONITRILE; 1 METHYL 4 NAPHTHALEN 2 YLPIPERIDINE 4 CARBOXYLIC ACID ETHYL ESTER; 4 (3,4 DICHLOROPHENYL) 1 METHYLPIPERIDINE 4 CARBOXYLIC ACID ETHYL ESTER; DOPAMINE TRANSPORTER; DOPAMINE UPTAKE INHIBITOR; NAPHTHYL GROUP; NORADRENALIN TRANSPORTER; PETHIDINE; PIPERIDINE DERIVATIVE; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DOPAMINE UPTAKE; DRUG DISCRIMINATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; LOCOMOTION; NONHUMAN; RAT; REACTION ANALYSIS; RECEPTOR AFFINITY; STRUCTURE ANALYSIS;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BRAIN; COCAINE; DISCRIMINATION LEARNING; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MEPERIDINE; NAPHTHALENES; NERVE TISSUE PROTEINS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS;

EID: 14944369844     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0401614     Document Type: Article

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