Human buprenorphine N-dealkylation is catalyzed by cytochrome P450 3A4

Drug Metabolism and Disposition

Volumn 26, Issue 8, 1998, Pages 818-821

  Kobayashi, Kaoru ^b   Yamamoto, Toshinori ^a   Chiba, Kan ^b   Tani, Masayoshi ^b   Shimada, Noriaki ^b   Ishizaki, Takashi ^b   Kuroiwa, Yukio ^b  

^a SHOWA UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BUPRENORPHINE; CYTOCHROME P450 ISOENZYME; MIDAZOLAM; TESTOSTERONE; THEBAINE; TRIAZOLAM;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DEALKYLATION; DRUG HYDROXYLATION; DRUG METABOLISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER MICROSOME METABOLISM; PRIORITY JOURNAL;

ALKYLATION; ANALGESICS, OPIOID; B-LYMPHOCYTES; BUPRENORPHINE; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; HUMANS; ISOENZYMES; KINETICS; MIXED FUNCTION OXYGENASES;

EID: 0031843967     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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