Hepatitis B virus X protein stimulates the Hedgehog-Gli activation through protein stabilization and nuclear localization of Gli1 in liver cancer cells

Cancer Letters

Volumn 309, Issue 2, 2011, Pages 176-184

  Kim, Hye Young ^a   Cho, Hyun Kook ^a   Hong, Sung Pyo ^b   Cheong, JaeHun ^a  

^a Pusan National University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Gli; HBV; HBx; Hedgehog; Hepatocellular carcinoma

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3;

ARTICLE; CANCER CELL CULTURE; CELL NUCLEUS; GENE EXPRESSION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HEP G2 CELLS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; LIVER; LIVER NEOPLASMS; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ERINACEIDAE; HEPATITIS B VIRUS;

EID: 79960839971     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.05.033     Document Type: Article

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