In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes

Biomaterials

Volumn 31, Issue 23, 2010, Pages 5953-5965

  Wang, Wei ^a   Li, Bo ^a   Li, Yanglin ^a   Jiang, Yangzi ^b   Ouyang, Hongwei ^b   Gao, Changyou ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

BMSCs; Cartilage regeneration; Fibrin gel; Gene therapy; PLGA sponge; TGF 1

Indexed keywords

ARTICULAR CARTILAGE DEFECTS; BONE MARROW MESENCHYMAL STEM CELLS; CARTILAGE DEFECTS; CARTILAGE REGENERATION; CARTILAGE REPAIR; CATIONIZED; CHITOSAN DERIVATIVES; DNA COMPLEX; EXPERIMENTAL GROUPS; FIBRIN GELS; FIBROUS TISSUE; GENE TRANSFECTION; GLYCOSAMINOGLYCANS; HETEROGENEOUS EXPRESSIONS; HYALINE CARTILAGE; IN-VITRO; IN-VIVO; N , N , N-TRIMETHYL CHITOSAN CHLORIDE; NEW ZEALAND WHITE RABBIT; PLASMID DNA; POLY-LACTIDE-CO-GLYCOLIDE; REGENERATED CARTILAGE; TRANSFECTION EFFICIENCY; TRANSFORMING GROWTH FACTORS; TYPE II;

BONE; CELL CULTURE; CHITIN; CHITOSAN; CHLORINE COMPOUNDS; DEFECTS; DNA; GELS; GENE THERAPY; GENETIC ENGINEERING; LIGAMENTS; NUCLEIC ACIDS; RESTORATION; STEM CELLS; SYNCHROTRONS;

CARTILAGE;

CHITOSAN DERIVATIVE; COLLAGEN TYPE 2; FIBRIN; GLYCOSAMINOGLYCAN; N,N,N TRIMETHYL CHITOSAN CHLORIDE; PLASMID DNA; POLYGLACTIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; DNA; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CHONDROPATHY; COMPOSITE MATERIAL; CONTROLLED STUDY; EXPRESSION VECTOR; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; HYALINE CARTILAGE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RABBIT; SCORING SYSTEM; STAINING; TISSUE REGENERATION; TISSUE REPAIR; ANIMAL; BONE MARROW CELL; CARTILAGE; CHEMISTRY; CYTOLOGY; MESENCHYMAL STROMA CELL; NUCLEOTIDE SEQUENCE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; BONE MARROW CELLS; CARTILAGE; DNA; DNA PRIMERS; FIBRIN; LACTIC ACID; MESENCHYMAL STEM CELLS; POLYGLYCOLIC ACID; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; MESENCHYMAL STROMAL CELLS;

ORYCTOLAGUS CUNICULUS;

EID: 77953811664     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.04.029     Document Type: Article

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