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Volumn 11, Issue 5, 2009, Pages

Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; COLLAGEN TYPE 10; COLLAGEN TYPE 2; COMPLEMENTARY DNA; FIREFLY LUCIFERASE; GAG PROTEIN; GREEN FLUORESCENT PROTEIN; LIPOCORTIN 5; MESSENGER RNA; PROTEOGLYCAN; BMP2 PROTEIN, HUMAN; BMP4 PROTEIN, HUMAN;

EID: 75649099043     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2822     Document Type: Article
Times cited : (128)

References (52)
  • 1
    • 34247587041 scopus 로고    scopus 로고
    • Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation
    • 1860068, 17316462
    • Kolf CM, Cho E, Tuan RS. Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation. Arthritis Res Ther 2007, 9:204. 1860068, 17316462.
    • (2007) Arthritis Res Ther , vol.9 , pp. 204
    • Kolf, C.M.1    Cho, E.2    Tuan, R.S.3
  • 3
    • 47149103922 scopus 로고    scopus 로고
    • Technology insight: adult mesenchymal stem cells for osteoarthritis therapy
    • Noth U, Steinert AF, Tuan RS. Technology insight: adult mesenchymal stem cells for osteoarthritis therapy. Nat Clin Pract Rheumatol 2008, 4:371-380.
    • (2008) Nat Clin Pract Rheumatol , vol.4 , pp. 371-380
    • Noth, U.1    Steinert, A.F.2    Tuan, R.S.3
  • 4
    • 33646367147 scopus 로고    scopus 로고
    • Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6
    • Estes BT, Wu AW, Guilak F. Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6. Arthritis Rheum 2006, 54:1222-1232.
    • (2006) Arthritis Rheum , vol.54 , pp. 1222-1232
    • Estes, B.T.1    Wu, A.W.2    Guilak, F.3
  • 5
    • 9344222791 scopus 로고    scopus 로고
    • Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports
    • Wakitani S, Mitsuoka T, Nakamura N, Toritsuka Y, Nakamura Y, Horibe S. Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports. Cell Transplant 2004, 13:595-600.
    • (2004) Cell Transplant , vol.13 , pp. 595-600
    • Wakitani, S.1    Mitsuoka, T.2    Nakamura, N.3    Toritsuka, Y.4    Nakamura, Y.5    Horibe, S.6
  • 7
    • 34250196490 scopus 로고    scopus 로고
    • Major biological obstacles for persistent cell-based regeneration of articular cartilage
    • 2206353, 17561986
    • Steinert AF, Ghivizzani SC, Rethwilm A, Tuan RS, Evans CH, Noth U. Major biological obstacles for persistent cell-based regeneration of articular cartilage. Arthritis Res Ther 2007, 9:213. 2206353, 17561986.
    • (2007) Arthritis Res Ther , vol.9 , pp. 213
    • Steinert, A.F.1    Ghivizzani, S.C.2    Rethwilm, A.3    Tuan, R.S.4    Evans, C.H.5    Noth, U.6
  • 9
    • 39749111452 scopus 로고    scopus 로고
    • Concepts in gene therapy for cartilage repair
    • 18313477, 2714368
    • Steinert AF, Nöth U, Tuan RS. Concepts in gene therapy for cartilage repair. Injury 2008, 39 Suppl 1:S97-S113. 18313477, 2714368.
    • (2008) Injury , vol.39 , Issue.SUPPL 1
    • Steinert, A.F.1    Nöth, U.2    Tuan, R.S.3
  • 11
    • 29744465669 scopus 로고    scopus 로고
    • Gene therapy for cartilage defects
    • Cucchiarini M, Madry H. Gene therapy for cartilage defects. J Gene Med 2005, 7:1495-1509.
    • (2005) J Gene Med , vol.7 , pp. 1495-1509
    • Cucchiarini, M.1    Madry, H.2
  • 12
    • 34248181957 scopus 로고    scopus 로고
    • Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair
    • Pagnotto MR, Wang Z, Karpie JC, Ferretti M, Xiao X, Chu CR. Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair. Gene Ther 2007, 14:804-813.
    • (2007) Gene Ther , vol.14 , pp. 804-813
    • Pagnotto, M.R.1    Wang, Z.2    Karpie, J.C.3    Ferretti, M.4    Xiao, X.5    Chu, C.R.6
  • 13
    • 33746958820 scopus 로고    scopus 로고
    • Limitations of using aggrecan and type X collagen as markers of chondrogenesis in mesenchymal stem cell differentiation
    • Mwale F, Stachura D, Roughley P, Antoniou J. Limitations of using aggrecan and type X collagen as markers of chondrogenesis in mesenchymal stem cell differentiation. J Orthop Res 2006, 24:1791-1798.
    • (2006) J Orthop Res , vol.24 , pp. 1791-1798
    • Mwale, F.1    Stachura, D.2    Roughley, P.3    Antoniou, J.4
  • 14
    • 0037331874 scopus 로고    scopus 로고
    • Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells
    • Gelse K, Mark K, Aigner T, Park J, Schneider H. Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells. Arthritis Rheum 2003, 48:430-441.
    • (2003) Arthritis Rheum , vol.48 , pp. 430-441
    • Gelse, K.1    Mark, K.2    Aigner, T.3    Park, J.4    Schneider, H.5
  • 15
    • 33750321974 scopus 로고    scopus 로고
    • Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice
    • Pelttari K, Winter A, Steck E, Goetzke K, Hennig T, Ochs BG, Aigner T, Richter W. Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum 2006, 54:3254-3266.
    • (2006) Arthritis Rheum , vol.54 , pp. 3254-3266
    • Pelttari, K.1    Winter, A.2    Steck, E.3    Goetzke, K.4    Hennig, T.5    Ochs, B.G.6    Aigner, T.7    Richter, W.8
  • 16
    • 0345827521 scopus 로고    scopus 로고
    • Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo
    • De Bari C, Dell'Accio F, Luyten FP. Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo. Arthritis Rheum 2004, 50:142-150.
    • (2004) Arthritis Rheum , vol.50 , pp. 142-150
    • De Bari, C.1    Dell'Accio, F.2    Luyten, F.P.3
  • 17
    • 0033861276 scopus 로고    scopus 로고
    • Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage
    • Kirsch T, Swoboda B, Nah H. Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage. Osteoarthritis Cartilage 2000, 8:294-302.
    • (2000) Osteoarthritis Cartilage , vol.8 , pp. 294-302
    • Kirsch, T.1    Swoboda, B.2    Nah, H.3
  • 18
    • 0035153590 scopus 로고    scopus 로고
    • Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes
    • 1867060, 11696438
    • Pfander D, Swoboda B, Kirsch T. Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes. Am J Pathol 2001, 159:1777-1783. 1867060, 11696438.
    • (2001) Am J Pathol , vol.159 , pp. 1777-1783
    • Pfander, D.1    Swoboda, B.2    Kirsch, T.3
  • 21
    • 0031055468 scopus 로고    scopus 로고
    • Construction of adenovirus vectors through Cre-lox recombination
    • 191254, 9032314
    • Hardy S, Kitamura M, Harris-Stansil T, Dai Y, Phipps ML. Construction of adenovirus vectors through Cre-lox recombination. J Virol 1997, 71:1842-1849. 191254, 9032314.
    • (1997) J Virol , vol.71 , pp. 1842-1849
    • Hardy, S.1    Kitamura, M.2    Harris-Stansil, T.3    Dai, Y.4    Phipps, M.L.5
  • 22
    • 0003205668 scopus 로고    scopus 로고
    • Molecular cloning: a laboratory manual
    • New York: CSHL Press, 3
    • Sambrook J, Russell DW. Molecular cloning: a laboratory manual. 2001, 1. New York: CSHL Press, 3.
    • (2001) , vol.1
    • Sambrook, J.1    Russell, D.W.2
  • 23
    • 0036189787 scopus 로고    scopus 로고
    • In vitro engineered cartilage constructs produced by press-coating biodegradable polymer with human mesenchymal stem cells
    • Noth U, Tuli R, Osyczka AM, Danielson KG, Tuan RS. In vitro engineered cartilage constructs produced by press-coating biodegradable polymer with human mesenchymal stem cells. Tissue Eng 2002, 8:131-144.
    • (2002) Tissue Eng , vol.8 , pp. 131-144
    • Noth, U.1    Tuli, R.2    Osyczka, A.M.3    Danielson, K.G.4    Tuan, R.S.5
  • 24
  • 25
    • 33644874153 scopus 로고    scopus 로고
    • High-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells
    • 1360216, 16312217
    • Penick KJ, Solchaga LA, Welter JF. High-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells. Biotechniques 2005, 39:687-691. 1360216, 16312217.
    • (2005) Biotechniques , vol.39 , pp. 687-691
    • Penick, K.J.1    Solchaga, L.A.2    Welter, J.F.3
  • 26
    • 0036201759 scopus 로고    scopus 로고
    • Formation of cartilage matrix proteins by BMP-transfected murine mesenchymal stem cells encapsulated in a novel class of alginates
    • Weber M, Steinert A, Jork A, Dimmler A, Thurmer F, Schutze N, Hendrich C, Zimmerman U. Formation of cartilage matrix proteins by BMP-transfected murine mesenchymal stem cells encapsulated in a novel class of alginates. Biomaterials 2002, 23:2003-2013.
    • (2002) Biomaterials , vol.23 , pp. 2003-2013
    • Weber, M.1    Steinert, A.2    Jork, A.3    Dimmler, A.4    Thurmer, F.5    Schutze, N.6    Hendrich, C.7    Zimmerman, U.8
  • 27
    • 38449102612 scopus 로고    scopus 로고
    • Cartilage histomorphometry
    • Hunziker EB. Cartilage histomorphometry. Methods Mol Med 2007, 135:147-166.
    • (2007) Methods Mol Med , vol.135 , pp. 147-166
    • Hunziker, E.B.1
  • 28
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • 113859, 11972351
    • Pfaffl MW, Horgan GW, Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 2002, 30:e36. 113859, 11972351.
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 29
    • 0003824990 scopus 로고
    • Form und bau der Geleknorpel in ihren Bezeihungen zur Funktion
    • Benninghoff A. Form und bau der Geleknorpel in ihren Bezeihungen zur Funktion. Z Zellforsch Mikrosk Anat Rec 1925, 783-825.
    • (1925) Z Zellforsch Mikrosk Anat Rec , pp. 783-825
    • Benninghoff, A.1
  • 31
    • 31644434203 scopus 로고    scopus 로고
    • Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum- and fat-derived cells
    • Park J, Gelse K, Frank S, Mark K, Aigner T, Schneider H. Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum- and fat-derived cells. J Gene Med 2006, 8:112-125.
    • (2006) J Gene Med , vol.8 , pp. 112-125
    • Park, J.1    Gelse, K.2    Frank, S.3    Mark, K.4    Aigner, T.5    Schneider, H.6
  • 32
    • 22144463885 scopus 로고    scopus 로고
    • Adenoviral-mediated transfer of TGF-beta1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures
    • 1360180, 16038778
    • Kawamura K, Chu CR, Sobajima S, Robbins PD, Fu FH, Izzo NJ, Niyibizi C. Adenoviral-mediated transfer of TGF-beta1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures. Exp Hematol 2005, 33:865-872. 1360180, 16038778.
    • (2005) Exp Hematol , vol.33 , pp. 865-872
    • Kawamura, K.1    Chu, C.R.2    Sobajima, S.3    Robbins, P.D.4    Fu, F.H.5    Izzo, N.J.6    Niyibizi, C.7
  • 35
    • 43949115205 scopus 로고    scopus 로고
    • Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells
    • Mueller MB, Tuan RS. Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells. Arthritis Rheum 2008, 58:1377-1388.
    • (2008) Arthritis Rheum , vol.58 , pp. 1377-1388
    • Mueller, M.B.1    Tuan, R.S.2
  • 36
    • 50949105736 scopus 로고    scopus 로고
    • Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells
    • Miljkovic ND, Cooper GM, Marra KG. Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells. Osteoarthritis Cartilage 2008, 16:1121-1130.
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1121-1130
    • Miljkovic, N.D.1    Cooper, G.M.2    Marra, K.G.3
  • 37
    • 47349115508 scopus 로고    scopus 로고
    • Impact of stromal cell composition on BMP-induced chondrogenic differentiation of mouse bone marrow derived mesenchymal cells
    • Taipaleenmaki H, Suomi S, Hentunen T, Laitala-Leinonen T, Saamanen AM. Impact of stromal cell composition on BMP-induced chondrogenic differentiation of mouse bone marrow derived mesenchymal cells. Exp Cell Res 2008, 314:2400-2410.
    • (2008) Exp Cell Res , vol.314 , pp. 2400-2410
    • Taipaleenmaki, H.1    Suomi, S.2    Hentunen, T.3    Laitala-Leinonen, T.4    Saamanen, A.M.5
  • 39
    • 24144458202 scopus 로고    scopus 로고
    • Differential effect of BMP4 on NIH/3T3 and C2C12 cells: implications for endochondral bone formation
    • Li G, Peng H, Corsi K, Usas A, Olshanski A, Huard J. Differential effect of BMP4 on NIH/3T3 and C2C12 cells: implications for endochondral bone formation. J Bone Miner Res 2005, 20:1611-1623.
    • (2005) J Bone Miner Res , vol.20 , pp. 1611-1623
    • Li, G.1    Peng, H.2    Corsi, K.3    Usas, A.4    Olshanski, A.5    Huard, J.6
  • 41
    • 42449106024 scopus 로고    scopus 로고
    • Articular cartilage repair using dedifferentiated articular chondrocytes and bone morphogenetic protein 4 in a rabbit model of articular cartilage defects
    • Lin L, Zhou C, Wei X, Hou Y, Zhao L, Fu X, Zhang J, Yu C. Articular cartilage repair using dedifferentiated articular chondrocytes and bone morphogenetic protein 4 in a rabbit model of articular cartilage defects. Arthritis Rheum 2008, 58:1067-1075.
    • (2008) Arthritis Rheum , vol.58 , pp. 1067-1075
    • Lin, L.1    Zhou, C.2    Wei, X.3    Hou, Y.4    Zhao, L.5    Fu, X.6    Zhang, J.7    Yu, C.8
  • 42
    • 43949090746 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in tissue engineering: the road from the laboratory to the clinic, part I (basic concepts)
    • Bessa PC, Casal M, Reis RL. Bone morphogenetic proteins in tissue engineering: the road from the laboratory to the clinic, part I (basic concepts). J Tissue Eng Regen Med 2008, 2:1-13.
    • (2008) J Tissue Eng Regen Med , vol.2 , pp. 1-13
    • Bessa, P.C.1    Casal, M.2    Reis, R.L.3
  • 43
    • 33845971522 scopus 로고    scopus 로고
    • Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
    • 1713256, 17194222
    • Bandyopadhyay A, Tsuji K, Cox K, Harfe BD, Rosen V, Tabin CJ. Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet 2006, 2:e216. 1713256, 17194222.
    • (2006) PLoS Genet , vol.2
    • Bandyopadhyay, A.1    Tsuji, K.2    Cox, K.3    Harfe, B.D.4    Rosen, V.5    Tabin, C.J.6
  • 47
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2002, 2:389-406.
    • (2002) Dev Cell , vol.2 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 48
    • 0033864484 scopus 로고    scopus 로고
    • Dual roles of Wnt signaling during chondrogenesis in the chicken limb
    • Hartmann C, Tabin CJ. Dual roles of Wnt signaling during chondrogenesis in the chicken limb. Development 2000, 127:3141-3159.
    • (2000) Development , vol.127 , pp. 3141-3159
    • Hartmann, C.1    Tabin, C.J.2
  • 50
    • 0042622575 scopus 로고    scopus 로고
    • Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees
    • 165041, 12723985
    • Mi Z, Ghivizzani SC, Lechman E, Glorioso JC, Evans CH, Robbins PD. Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees. Arthritis Res Ther 2003, 5:R132-139. 165041, 12723985.
    • (2003) Arthritis Res Ther , vol.5
    • Mi, Z.1    Ghivizzani, S.C.2    Lechman, E.3    Glorioso, J.C.4    Evans, C.H.5    Robbins, P.D.6
  • 51
    • 0037869555 scopus 로고    scopus 로고
    • Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7
    • Hidaka C, Goodrich LR, Chen CT, Warren RF, Crystal RG, Nixon AJ. Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7. J Orthop Res 2003, 21:573-583.
    • (2003) J Orthop Res , vol.21 , pp. 573-583
    • Hidaka, C.1    Goodrich, L.R.2    Chen, C.T.3    Warren, R.F.4    Crystal, R.G.5    Nixon, A.J.6
  • 52
    • 39749180922 scopus 로고    scopus 로고
    • Cell-based resurfacing of large cartilage defects: long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis
    • Gelse K, Muhle C, Franke O, Park J, Jehle M, Durst K, Goken M, Hennig F, Mark K, Schneider H. Cell-based resurfacing of large cartilage defects: long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis. Arthritis Rheum 2008, 58:475-488.
    • (2008) Arthritis Rheum , vol.58 , pp. 475-488
    • Gelse, K.1    Muhle, C.2    Franke, O.3    Park, J.4    Jehle, M.5    Durst, K.6    Goken, M.7    Hennig, F.8    Mark, K.9    Schneider, H.10


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