Selective gene expression in brain microglia mediated via adeno-associated virus type 2 and type 5 vectors

Gene Therapy

Volumn 10, Issue 8, 2003, Pages 657-667

  Cucchiarini, M ^a,c   Ren, X L ^a   Perides, G ^b   Terwilliger, E F ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

CNS; Gene transfer; Microglia; rAAV; Tissue specificity

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CD11 ANTIGEN; CD18 ANTIGEN; CD68 ANTIGEN; CD8 ANTIGEN; GENOMIC DNA; GLIAL FIBRILLARY ACIDIC PROTEIN; RED FLUORESCENT PROTEIN; VIRUS PROTEIN;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL LINEAGE; CELL TYPE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; FEASIBILITY STUDY; GENE CONTROL; GENE EXPRESSION; GENETIC SELECTION; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; SEROTYPE; TARGET CELL; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; VIRUS TYPING;

ANIMALS; BRAIN; BRAIN DISEASES; DEPENDOVIRUS; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENETIC ENGINEERING; GENETIC VECTORS; HUMANS; MACROPHAGES, ALVEOLAR; MALE; MICROGLIA; RATS; RATS, SPRAGUE-DAWLEY; SEROTYPING; TRANSDUCTION, GENETIC;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS 2; ADENOVIRIDAE; ANIMALIA; DNA VIRUSES; MURINAE;

EID: 0012296395     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301925     Document Type: Article

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