Adenoviral-mediated transfer of TGF-β1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures

Experimental Hematology

Volumn 33, Issue 8, 2005, Pages 865-872

  Kawamura, Koichiro ^a   Chu, Constance R ^a   Sobajima, Satoshi ^a   Robbins, Paul D ^a,b   Fu, Freddie H ^a   Izzo, Nicholas J ^a   Niyibizi, Christopher ^c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; AGGRECAN; COLLAGEN TYPE 10; COLLAGEN TYPE 2; GROWTH FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CARTILAGE MATRIX; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; STAINING; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROGENESIS; COLLAGEN TYPE II; COLLAGEN TYPE X; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MESENCHYMAL STEM CELLS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 22144463885     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2005.05.010     Document Type: Article

References (46)

1. L. Hangody, G. Kish, Z. Karpati, and I. Szerb Arthroscopic autogenous osteochondral mosaicplasty for the treatment of femoral chondyle articular defects Knee Surg Sports Traumatol Arthrosc 5 1997 262 267
2. C.R. Chu, F.R. Convery, W.H. Akeson, M. Meyer, and D. Amiel Articular cartilage transplantation. Clinical results in the knee Clin Orthop 360 1999 159 168
3. M. Brittberg, A. Lindahl, A. Nilsson, C. Ohlsson, O. Isaksson, and L. Peterson Treatment of cartilage defects in the knee with autologous chondrocyte transplantation N Engl J Med 331 1994 889 895
4. F. Shapiro, S. Koide, and M.J. Glimcher Cell origin and differentiation in the repair of full thickness defects of articular cartilage J Bone Joint Surg 75-A 1993 532 552
5. T. Furukawa, D.R. Eyre, S. Koide, and M.J. Glimcher Biochemical studies on repair cartilage resurfacing experimental defects in the rabbit knee J Bone Joint Surg 62-B 1980 79 89
6. S.B. Trippel, M.T. Corvol, M.F. Dumontier, R. Rappaport, H.H. Hung, and H.J. Mankin Effect of somatomedin-C/insulin-like growth factor I and growth hormone on cultured growth plate and articular chondrocyte Pediatr Res 25 1989 76 82
7. C.H. Evans, S.C. Ghivizzani, P. Smith, F.D. Studer, Z. Mi, and P.D. Robbins Using gene therapy to protect and restore cartilage Clin Orthop Relat Res 379S suppl 2000 214 219
8. M.F. Pittenger, A.M. Mackay, and S.C. Beck Multilineage potential of adult human mesenchymal stem cells Science 285 1999 143 147
9. D.J. Prockop Marrow stromal cells as stem cells for non-hematopoietic tissues Science 276 1997 71 74
10. P.A. Zuk, M. Zhu, and P. Ashjian Human adipose tissue is a source of multipotent stem cells Mol Biol Cell 13 2002 4279 4295
11. R.J. Jankowski, B.M. Deasy, and J. Huard Muscle-derived stem cells Gene Ther 9 2002 642 647
12. J.M. Murphy, K. Dixon, S. Beck, D. Fabian, A. Feldman, and F. Barry Activity of mesenchymal stem cells from patients with advanced osteoarthritis Arthritis Rheum 46 3 2002 704 713
13. Z. Mi, S.C. Ghivizzani, and E.R. Lechman Adenovirus-mediated gene transfer of insulin-like growth factor I stimulates proteoglycan synthesis in rabbit joints Arthritis Rheum 43 2000 2563 2570
14. A.I. Caplan Mesenchymal stem cells J Orthop Res 9 1991 641 665
15. S. Gronthos, A.C.W. Zannettino, and S.J. Hay Molecular and cellular characterization of highly purified stromal stem cells derived from human bone marrow J Cell Sci 116 2003 1827 1835
16. H. Nochi, J.H. Sung, J. Lou, H.D. Adkisson, W.J. Maloney, and K.A. Hruska Adenovirus mediated BMP-13 gene transfer induces chondrogenic differentiation of murine mesenchymal progenitor cells J Bone Miner Res 19 2004 111 122
17. E.Y. Snyder, and A.L. Vescovi The possibilities/perplexities of stem cells Nat Biotechnol 18 2000 827 828
18. G. Ferrari, G. Cusella-De Angelis, and M. Colette Muscle regeneration by bone marrow-derived myogenic progenitors Science 279 1998 11 16
19. D. Orlic, J. Kajstura, and S. Chimenti Bone marrow cells regenerate infarcted myocardium Nature 410 2001 701 705
20. N.D. Theise, M. Nimmakayalu, and R. Gardner Liver from bone marrow in humans Hepatology 32 2000 11 16
21. B. Johnstone, T.M. Herring, A.I. Caplan, V.M. Goldberg, and J.U. Yoo In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells Exp Cell Res 38 1998 265 272
22. F. Barry, E. Raymond, E. Boynton, B. Liu, and M. Murphy Chondrogenic differentiation of mesenchymal stem cells from bone marrow; Differentiation- dependent gene expression of matrix components Exp Cell Res 268 2001 189 200
23. M. Oyama, A. Tatlock, and K. Kavalkovich Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passaging Gene Ther 6 1999 321 329
24. A.M. Mackay, S.C. Beck, J.M. Murphy, F. Barry, C.O. Chichester, and M. Pittenger Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow Tissue Eng 4 1998 415 428
25. S. Pizette, and L. Niswander BMPs are required at two steps of limb chondrogenesis: formation of prechondrogenic condensations and their differentiation into chondrocytes Dev Biol 219 2000 237 249
26. A.J. Nixon, B.D. Brower-Toland, and S.J. Bent Insulin-like growth factor therapy: Applications for cartilage repair Clin Orthop Res 379S 2000 201 213
27. M. Milne, J.M. Quail, and D.T. Barab Dexamethasone stimulated osteogenic differentiation in vertebral and femoral bone marrow cell cultures: Comparison of IGF-1 gene expression J Cell Biochem 71 1998 381 391
28. H. Inoue, Y. Kato, M. Iwamoto, Y. Hiraki, M. Sakuda, and F. Suzuki Stimulation of cartilage-matrix proteoglycan synthesis by morphologically transformed chondrocytes grown in the presence of fibroblast growth factor and transforming growth factor-β J Cell Physiol 138 1989 329 337
29. T.I. Morales Transforming growth factor-β and insulin-like growth factor-1 restore proteoglycan metabolism of bovine articular cartilage after depletion by retinoic acid Arch Biochem Biophys 315 1994 190 198
30. A.J. Nixon, L.A. Fortier, J. Villiums, and H. Mohammed Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites J Orthop Res 17 1999 475 487
31. L.A. Fortier, O.H. Mohammed, G. Lust, and A.J. Nixon Insulin-like growth factor-1 enhances cell-based repair of articular cartilage J Bone Joint Surg 84B 2002 276 288
32. L.A. Fortier, C.E. Balkman, L.J. Sandell, A. Ratcliffe, and A.J. Nixon Insulin-like growth factor-I gene expression patterns during spontaneous repair of acute articular cartilage injury J Orthop Res 19 2001 720 728
33. G.J.V.M. van Osch, W.B. van den Berg, E.B. Hunziker, and H.J. Hauselmann Differential effects of IGF-1 and TGFβ-2 on the assembly of proteoglycans in pericellular and territorial matrix by cultured bovine articular chondrocytes Osteoarthritis Cartilage 6 1998 187 195
34. P. Smith, D. Shuler, and I. Georgescu Genetic enhancement of matrix synthesis by articular chondrocyte Arthritis Rheum 43 2000 1156 1164
35. A.J. Nixon, J.T. Lillich, N. Bruton-Wurster, G. Lust, and H.O. Mohammed Differentiated cellular function in fetal chondrocytes cultured with insulin-like growth factor-I and transforming growth factor-β J Orthop Res 16 1998 531 541
36. H. Madry, R. Padera, and J. Seidel Gene transfer of a human insulin-like growth factor I cDNA enhances tissue engineering of cartilage Hum Gene Ther 13 2002 1621 1630
37. T. Fukumoto, J.W. Sperling, and A. Sanyal Combined effects of insulin-like growth factor-1 and transforming growth factor-β1 on periosteal mesenchymal cells during chondrogenesis in vitro Osteoarthritis and Cartilage 11 2003 55 64
38. C.M. Mierisch, P.C. Anderson, G. Balian, and D.R. Diduch Treatment with insulin-like growth factor-1 increases chondrogenesis by periosteum in vitro Connect Tissue Res 43 2002 559 568
39. P. Robbins, and S.C. Ghivizzani Viral vector for gene therapy Pharmacol Ther 80 1998 35 47
40. B.D. Brower-Toland, R.A. Saxer, and L.R. Goodrich Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function Hum Gene Ther 12 2001 117 129
41. J.P. Annes, J.S. Munger, and D.B. Rifkin Making sense of latent TGF-β activation J Cell Sci 116 2003 217 224
42. T. Ikenoue, M.C.D. Trindade, and M.S. Lee Mechanoregulation of human articular chondrocyte aggrecan and type II collagen expression by intermittent hydrostatic pressure in vitro J Orthop Res 21 2003 110 116
43. D.P. Lennon, S.E. Haynesworth, R.G. Young, J.E. Dennis, and I.A. Caplan A chemically defined medium supports in vitro proliferation and maintains the osteochondral potential of rat marrow-derived mesenchymal stem cells Exp Cell Res 219 1995 354 362
44. A.A. Worster, B.D. Brower-Toland, L.A. Fortier, S.J. Bent, J. Williams, and A.J. Nixon Chondrocytes differentiation of mesenchymal stem cells sequentially exposed to transforming growth factor-β1 in monolayer and insulin-like growth factor-1 in a three-dimensional matrix J Orthop Res 19 2001 738 749
45. C.M. Ferguson, E.M. Schwarz, P.R. Reynolds, J.E. Puzas, R.N. Rosier, and R.J. O'Keefe Smad2 and 3 mediate transforming growth factor-β1-induced inhibition of chondrocyte maturation Endocrinology 141 2000 4728 4735
46. Y. Kato, M. Iwamoto, T. Koike, F. Suzuki, and Y. Takano Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: regulation by transforming growth factor β and serum factors Proc Natl Acad Sci U S A 85 1988 9552 9556