Possible role for the thioredoxin system in the protective effects of probucol in the pancreatic islets of diabetic rats

Clinical and Experimental Pharmacology and Physiology

Volumn 38, Issue 8, 2011, Pages 528-533

  Liu, Ji Hong ^a   Liu, Dong Fang ^a   Wang, Nan Nan ^a   Lin, Hai Ling ^a   Mei, Xi ^a  

^a THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Oxidative stress; Probucol; Thioredoxins; Type 2 diabetes mellitus

Indexed keywords

CATALASE; GLUCOSE; INSULIN; MALONALDEHYDE; PLACEBO; PROBUCOL; SUPEROXIDE DISMUTASE; THIOREDOXIN; THIOREDOXIN INTERACTING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; COLORIMETRY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HYPOINSULINEMIA; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; LIPID PEROXIDATION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET CELL FUNCTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; BODY WEIGHT; CARRIER PROTEINS; CONTROL GROUPS; DIABETES MELLITUS, EXPERIMENTAL; DIETARY FATS; INSULIN; ISLETS OF LANGERHANS; MALE; OXIDATIVE STRESS; PROBUCOL; PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; THIOREDOXINS;

EID: 79960737369     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2011.05545.x     Document Type: Article

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