Combined effect of probucol and insulin on renal damage in diabetic rats fed a high cholesterol diet

European Journal of Pharmacology

Volumn 548, Issue 1-3, 2006, Pages 174-180

  Yoshida, Masumi ^a   Kimura, Hitoshi ^a   Kyuki, Kouhei ^a   Ito, Mikio ^b  

^a Nihon Bioresearch Inc   (Japan)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

Diabetes; Hyperglycemia; Hyperlipidemia; Lipid peroxide; Renal injury

Indexed keywords

ISOPHANE INSULIN; NPHISZILIN; PROBUCOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; EVALUATION; HISTOPATHOLOGY; KIDNEY DISTAL TUBULE; KIDNEY INJURY; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALBUMINURIA; ANIMALS; ANTICHOLESTEREMIC AGENTS; ANTIOXIDANTS; BLOOD GLUCOSE; CHOLESTEROL; CHOLESTEROL, DIETARY; DIABETES MELLITUS, EXPERIMENTAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; HYPOGLYCEMIC AGENTS; INSULIN; KIDNEY DISEASES; LIPID PEROXIDES; MALE; PROBUCOL; RATS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES;

EID: 33748698246     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.07.053     Document Type: Article

References (24)

1. Agardh C.-D., Stenram U., Torffvit O., and Agardh E. Effects of inhibition of glycation and oxidative stress on the development of diabetic nephropathy in rats. J. Diabetes Its Complicat. 16 (2002) 395-400
2. Baumastark M.W., Aristegui R., Zoller T., Frey I., Berg A., and Keul J. Probucol incorporated into LDL particles in vivo, inhibits generation of lipid peroxides more effectively than endogenous antioxidants alone. Clin. Biochem. 25 (1992) 395-397
3. Fabris B., Candido R., Armini L., Fischetti F., Calci M., Bardelli M., Fazio M., Campanacci L., and Carretta R. Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats. J. Hypertens. 17 (1999) 1925-1931
4. Franceschini G., Chiesa G., and Sirtori C.R. Probucol increases cholesteryl ester transfer protein activity in hypercholesterolaemic patients. Eur. J. Clin. Invest. 21 (1991) 384-388
5. Gorogawa S., Kajimoto Y., Umayahara Y., Kaneto H., Watanabe H., Kuroda A., Kawamori D., Yasuda T., Matsuhisa M., Yamasaki Y., and Hori M. Probucol preserve pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes. Diabetes Res. Clin. Prac. 57 (2002) 1-10
6. Green A., and Hougaard P. Epidemiological studies of diabetes mellitus in Denmark. Diabetologia 26 (1984) 190-194
7. Hadjadj S., Duly-Bouhanick B., Bekherraz A., Brldoux F., Gallois Y., Mauco G., Ebran J., and Marre M. Serum triglycerides are a predictive factor for the development and the progression of renal and retinal complications in patients with type 1 diabetes. Diabetes Metab. 230 (2004) 43-51
8. Ha H., and Lee H.B. Oxidative stress in diabetic nephropathy: basic and clinical information. Curr. Diabetes Rep. 1 (2001) 282-287
9. Hunt J.V., Smith C.C., and Wolff S.P. Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 39 (1991) 1420-1424
10. Ito M., Kondo Y., Kakatani A., Hayashi K., and Naruse A. Characterization of low dose streptozotocin-induced progressive diabetes in mice. Environ. Toxicol. Pharmacol. 9 (2001) 71-78
11. Matsushita M., Yoshino G., Iwai M., Matsuwa K., Morita M., Iwatani I., Yoshida M., Kazumi T., and Baba S. Protective effect of probucol on alloxan diabetes in rats. Diabetes Res. Clin. 7 (1989) 313-316
12. Man Z.-W., Zhu M., Noma Y., Toide K., Sato T., Asahi Y., Hirashima T., Mori S., Kawano K., Mizuno A., Sano T., and Shima K. Impaired β-cell function and deposition of fat droplets in the pancreas as a consequence of hypertriglyceridemia in OLETF rat, a model of spontaneous NIDDM. Diabetes 46 (1977) 1718-1724
13. Nikkila E.A., and Kekki M. Plasma triglyceride transport kinetics in diabetes mellitus. Metabolism 22 (1973) 1-22
14. Nikkila E.A., and Hormila P. Serum lipid and lipoproteins in insulin-treated diabetes. Demonstration of increased high density lipoprotein concentrations. Diabetes 27 (1978) 1078-1085
15. Reaven G.M., and Greenfield M.S. Diabetic hypertriglyceridemia. Evidence for three clinical syndrome. Diabetes 30 Suppl. 2 (1981) 66-75
16. Regnstrom J., Walldius D., Carlson L.A., and Nilsson J. Effect of probucol treatment on susceptibility of low density lipoprotein isolated from hypercholesterolemic patients to became oxidatively modified in vivo. Atherosclerosis 82 (1990) 43-51
17. Rossing P., Rossing K., Jacobsen P., and Parving H.-H. Unchanged incidence of diabetic nephropathy in IDDM patients. Diabetes 44 (1995) 739-743
18. Sakurai T., and Tsuchiya S. Superoxide production from nonenzymatically glycation protein. FEBS Lett. 236 (1988) 406-410
19. Scheuer H., Gwinner W., Hohbach J., Grone E.F., Brandes R.P., Malle E., Olbricht C.J., Walli A.K., and Grone H.J. Oxidative stress in hyperlipidemia-induced renal damage. Am. J. Physiol., Renal Physiol. 278 (2000) F63-F74
20. Schwarts C.J. The probucol experience: a review of the past and a look at the future. Am. J. Cardiol. 62 (1988) 1B-5B
21. Shestakova M.V., Dedov I.I., Neverov N.I., Severgina E.S., Diuzhev T.G., and Ponomarev A.B. Hyperlipidemia as a factor in the development and progress of diabetic nephropathy. Probl. Endokrinol. (Mosk) 39 (1993) 7-9
22. Tsutsumi K., Inoue Y., and Yoshida C. Acceleration of development of diabetic cataract by hyperlipidemia and low high-density lipoprotein in rats. Biol. Pharm. Bull. 22 (1999) 37-41
23. Yagi K. A simple fluorometric assay for lipoperoxide in blood plasma. Biochem. Med. 15 (1976) 212-216
24. Yoshida M., Kimura H., Kyuki K., and Ito M. Combined effect of probucol and insulin on cataracts of diabetic rats fed a high cholesterol diet. Eur. J. Pharmacol. 513 (2005) 159-168