Production and characterization of LEA29Y, a variant of cytotoxic T-lymphocyte antigen 4-immunoglobulin, in Pichia pastoris

Applied Microbiology and Biotechnology

Volumn 91, Issue 3, 2011, Pages 543-551

  Wan, Lin ^a   Zhu, Shengyun ^a   Li, Yingying ^a   Liu, Shan ^a   Yang, Hao ^a   Li, Shengfu ^a   Li, Youping ^a   Cheng, Jingqiu ^a   Lu, Xiaofeng ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

CTLA4Ig; Immunosuppression; Pichia pastoris

Indexed keywords

AUTOIMMUNE DISEASE; BIOLOGICAL FUNCTIONS; COSTIMULATORY PATHWAYS; CTLA4IG; CULTURE MEDIUM; CYTOTOXIC; DOSE-DEPENDENT MANNER; EXPRESSION SYSTEM; GRAFT REJECTION; GRAFT-VERSUS-HOST DISEASE; IMMUNOSUPPRESSION; INDUCTION TIME; INOCULUM DENSITY; LYMPHOCYTE PROLIFERATION; MAMMALIAN CELLS; METHANOL CONCENTRATION; N-LINKED GLYCOSYLATION; P. PASTORIS; PICHIA PASTORIS; PNGASE F; POTENT INHIBITOR; PROTEIN EXPRESSIONS; RAJI CELLS; SPECIFIC BINDING; TRANSPLANT REJECTION;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL CULTURE; ANTIGENS; CELL PROLIFERATION; CLONING; DISEASE CONTROL; GENE ENCODING; GRAFTING (CHEMICAL); MAMMALS; METHANOL; PURIFICATION;

YEAST;

AGAROSE; BELATACEPT; METHANOL; NICKEL;

ANTIBODY; ANTIGEN; BIOTECHNOLOGY; CYTOLOGY; DISEASE TREATMENT; DOSE-RESPONSE RELATIONSHIP; GENE EXPRESSION; IMMUNE RESPONSE; INHIBITOR; PEROVSKITE; TOXICOLOGY; YEAST;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; CULTURE MEDIUM; DEGLYCOSYLATION; GLYCOSYLATION; GRAFT REJECTION; HUMAN; HUMAN CELL; INOCULATION; LYMPHOCYTE PROLIFERATION; NONHUMAN; PICHIA PASTORIS; PROTEIN EXPRESSION; RAJI CELL;

ANTIGENS, CD28; B7 ANTIGENS; CELL LINE, TUMOR; CTLA-4 ANTIGEN; HUMANS; IMMUNOCONJUGATES; IMMUNOGLOBULINS; LYMPHOCYTE ACTIVATION; PICHIA; PLASMIDS; T-LYMPHOCYTES, CYTOTOXIC;

MAMMALIA; PICHIA PASTORIS;

EID: 79960737317     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3277-4     Document Type: Article

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