-
1
-
-
77953079396
-
Update in communityacquired and nosocomial pneumonia
-
Torres A, Rello J. (2010) Update in communityacquired and nosocomial pneumonia 2009. Am. J. Respir. Crit. Care Med. 181:782-7.
-
(2010)
Am. J. Respir. Crit. Care Med.
, vol.181
, pp. 782-787
-
-
Torres, A.1
Rello, J.2
-
3
-
-
38149053617
-
A comparative study of bacteremic and non-bacteremic pneumococcal pneumonia
-
Jover F, et al. (2008) A comparative study of bacteremic and non-bacteremic pneumococcal pneumonia. Eur. J. Intern. Med. 19:15-21.
-
(2008)
Eur. J. Intern. Med.
, vol.19
, pp. 15-21
-
-
Jover, F.1
-
4
-
-
0029128018
-
Epidemiology of nosocomial pneumonia
-
Craven DE, Steger KA. (1995) Epidemiology of nosocomial pneumonia. Chest. 108:1S-16S.
-
(1995)
Chest
, vol.108
-
-
Craven, D.E.1
Steger, K.A.2
-
5
-
-
77958134727
-
Bacteremic community-acquired pneumonia due to Klebsiella pneumoniae: Clinical and microbiological characteristics in Taiwan, 2001-2008
-
Lin YT, Jeng YY, Chen TL, Fung CP. (2010) Bacteremic community-acquired pneumonia due to Klebsiella pneumoniae: clinical and microbiological characteristics in Taiwan, 2001-2008. BMC Infect. Dis. 10:307.
-
(2010)
BMC Infect. Dis.
, vol.10
, pp. 307
-
-
Lin, Y.T.1
Jeng, Y.Y.2
Chen, T.L.3
Fung, C.P.4
-
6
-
-
77951260924
-
The role of patternrecognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S. (2010) The role of patternrecognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11:373-84.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
7
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O, Akira S. (2010) Pattern recognition receptors and inflammation. Cell. 140:805-20.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
8
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. (2004) Toll-like receptor signalling. Nat. Rev. Immunol. 4:499-511.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
9
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
Rathinam VAK, et al. (2010) The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat. Immunol. 11:395-402.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 395-402
-
-
Rathinam, V.A.K.1
-
10
-
-
66449088641
-
Pathogen recognition and inflammatory signaling in innate immune defenses
-
Mogensen TH. (2009) Pathogen recognition and inflammatory signaling in innate immune defenses. Clin. Microbiol. Rev. 22:240-73.
-
(2009)
Clin. Microbiol. Rev.
, vol.22
, pp. 240-273
-
-
Mogensen, T.H.1
-
12
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. (2002) The protein kinase complement of the human genome. Science. 298:1912-34.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
13
-
-
77950842431
-
Kinome profiling of clinical cancer specimens
-
Parikh K, Peppelenbosch MP. (2010) Kinome profiling of clinical cancer specimens. Cancer Res.70:2575-8.
-
(2010)
Cancer Res
, vol.70
, pp. 2575-2578
-
-
Parikh, K.1
Peppelenbosch, M.P.2
-
14
-
-
33846922738
-
Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia
-
Renckens R, et al. (2007) Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia. Blood. 109:1593-601.
-
(2007)
Blood
, vol.109
, pp. 1593-1601
-
-
Renckens, R.1
-
15
-
-
33745131127
-
Kinome analysis reveals nongenomic glucocorticoid receptordependent inhibition of insulin signaling
-
Lowenberg M, et al. (2006) Kinome analysis reveals nongenomic glucocorticoid receptordependent inhibition of insulin signaling. Endocrinology.147:3555-62.
-
(2006)
Endocrinology
, vol.147
, pp. 3555-3562
-
-
Lowenberg, M.1
-
16
-
-
33846254038
-
Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia
-
van Baal JWPM, et al. (2006) Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia. Cancer Res. 66:11605-12.
-
(2006)
Cancer Res
, vol.66
, pp. 11605-11612
-
-
van Baal, J.W.P.M.1
-
17
-
-
60249095354
-
Extracellular ligation-dependent CD45RB enzymatic activity negatively regulates lipid raft signal transduction
-
Parikh K, Poppema S, Peppelenbosch MP, Visser L. (2009) Extracellular ligation-dependent CD45RB enzymatic activity negatively regulates lipid raft signal transduction. Blood. 113:594-603.
-
(2009)
Blood
, vol.113
, pp. 594-603
-
-
Parikh, K.1
Poppema, S.2
Peppelenbosch, M.P.3
Visser, L.4
-
18
-
-
40749096784
-
Evidence for a minimal eukaryotic phosphoproteome?
-
Diks SH, et al. (2007) Evidence for a minimal eukaryotic phosphoproteome? PLoS ONE. 2:e777.
-
(2007)
PLoS ONE
, vol.2
-
-
Diks, S.H.1
-
19
-
-
2142652249
-
Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils
-
Strassheim D, et al. (2004) Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils. J. Immunol. 172:5727-33.
-
(2004)
J. Immunol.
, vol.172
, pp. 5727-5733
-
-
Strassheim, D.1
-
20
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning BD, Cantley LC. (2007) AKT/PKB signaling: navigating downstream. Cell. 129:1261-74.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
21
-
-
33646111903
-
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning
-
Cai SL, et al. (2006) Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning. J. Cell Biol. 173:279-89.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 279-289
-
-
Cai, S.L.1
-
22
-
-
34547209343
-
Roles of the Raf/ MEK/ ERK pathway in cell growth, malignant transformation and drug resistance
-
McCubrey JA, et al. (2007) Roles of the Raf/ MEK/ ERK pathway in cell growth, malignant transformation and drug resistance. Biochim. Biophys. Acta.1773:1263-84.
-
(2007)
Biochim. Biophys. Acta.
, vol.1773
, pp. 1263-1284
-
-
McCubrey, J.A.1
-
23
-
-
46849106085
-
Relations between the mitogen- activated protein kinase and the cAMP-dependent protein kinase pathways: Comradeship and hostility
-
Gerits N, Kostenko S, Shiryaev A, Johannessen M, Moens U. (2008) Relations between the mitogen- activated protein kinase and the cAMP-dependent protein kinase pathways: comradeship and hostility. Cell. Signal. 20:1592-607.
-
(2008)
Cell. Signal.
, vol.20
, pp. 1592-1607
-
-
Gerits, N.1
Kostenko, S.2
Shiryaev, A.3
Johannessen, M.4
Moens, U.5
-
24
-
-
0035133227
-
Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
-
Kim AH, Khursigara G, Sun X, Franke TF, Chao MV. (2001) Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol. Cell. Biol. 21:893-901.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 893-901
-
-
Kim, A.H.1
Khursigara, G.2
Sun, X.3
Franke, T.F.4
Chao, M.V.5
-
25
-
-
0027534990
-
Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum
-
Webster MK, Goya L, Ge Y, Maiyar AC, Firestone GL. (1993) Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Mol. Cell. Biol. 13:2031-40.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2031-2040
-
-
Webster, M.K.1
Goya, L.2
Ge, Y.3
Maiyar, A.C.4
Firestone, G.L.5
-
26
-
-
58149250280
-
Review of the activation of TGF-beta in immunity
-
Taylor AW. (2009) Review of the activation of TGF-beta in immunity. J. Leukoc. Biol. 85:29-33.
-
(2009)
J. Leukoc. Biol.
, vol.85
, pp. 29-33
-
-
Taylor, A.W.1
-
27
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways
-
Alarcón C, et al. (2009) Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell. 139:757-69.
-
(2009)
Cell
, vol.139
, pp. 757-769
-
-
Alarcón, C.1
-
28
-
-
23844516979
-
Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: A microarray analysis
-
Yew EHJ, et al. (2005) Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis. J. Neurochem. 94:943-56.
-
(2005)
J. Neurochem.
, vol.94
, pp. 943-956
-
-
Yew, E.H.J.1
-
29
-
-
2442649342
-
Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress
-
Morrow G, Samson M, Michaud S, Tanguay RM. (2004) Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. FASEB J. 18:598-9.
-
(2004)
FASEB J
, vol.18
, pp. 598-599
-
-
Morrow, G.1
Samson, M.2
Michaud, S.3
Tanguay, R.M.4
-
30
-
-
67649204120
-
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP- dependent protein kinase pathway
-
Zhang G, et al. (2009) Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP- dependent protein kinase pathway. J. Immunol. 182:7997-8004.
-
(2009)
J. Immunol.
, vol.182
, pp. 7997-8004
-
-
Zhang, G.1
-
31
-
-
0037881900
-
Regulation of Fyn through translocation of activated Lck into lipid rafts
-
Filipp D, et al. (2003) Regulation of Fyn through translocation of activated Lck into lipid rafts. J. Exp. Med. 197:1221-7.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1221-1227
-
-
Filipp, D.1
-
32
-
-
0030995505
-
Identification of novel human WW domain-containing proteins by cloning of ligand targets
-
Pirozzi G, et al. (1997) Identification of novel human WW domain-containing proteins by cloning of ligand targets. J. Biol. Chem. 272:14611-6.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14611-14616
-
-
Pirozzi, G.1
-
33
-
-
1342329483
-
C-terminal Src kinase controls acute inflammation and granulocyte adhesion
-
Thomas RM, et al. (2004) C-terminal Src kinase controls acute inflammation and granulocyte adhesion. Immunity. 20:181-91.
-
(2004)
Immunity
, vol.20
, pp. 181-191
-
-
Thomas, R.M.1
-
34
-
-
60649085974
-
Csk-binding protein can regulate Lyn signals controlling cell morphology
-
Ingley E. (2009) Csk-binding protein can regulate Lyn signals controlling cell morphology. Int. J. Biochem. Cell. Biol. 41:1332-43.
-
(2009)
Int. J. Biochem. Cell. Biol.
, vol.41
, pp. 1332-1343
-
-
Ingley, E.1
-
35
-
-
77956915812
-
Src-dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics
-
Lee HH, et al. (2010) Src-dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics. J. Cell Sci. 123:3368-77.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 3368-3377
-
-
Lee, H.H.1
-
36
-
-
38449099025
-
Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury
-
Lee HS, et al. (2007) Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury. J. Immunol. 179:7001-11.
-
(2007)
J. Immunol.
, vol.179
, pp. 7001-7011
-
-
Lee, H.S.1
-
38
-
-
12944250922
-
Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A
-
Fang X, et al. (2000) Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. Proc. Natl. Acad. Sci. U. S. A. 97:11960-5.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 11960-11965
-
-
Fang, X.1
-
39
-
-
0035984569
-
Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation
-
Rosendahl A, et al. (2002) Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation. Am. J. Respir. Cell Mol. Biol. 27:160-9.
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.27
, pp. 160-169
-
-
Rosendahl, A.1
-
40
-
-
0035797529
-
Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred
-
Newman JH, et al. (2009) Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred. N. Engl. J. Med. 345:319-24.
-
(2009)
N. Engl. J. Med.
, vol.345
, pp. 319-324
-
-
Newman, J.H.1
-
41
-
-
34247570335
-
Interleukin-1beta induces MMP-9 expression via p42/p44 MAPK, p38 MAPK, JNK, and nuclear factor-kappaB signaling pathways in human tracheal smooth muscle cells
-
Liang KC, et al. (2007) Interleukin-1beta induces MMP-9 expression via p42/p44 MAPK, p38 MAPK, JNK, and nuclear factor-kappaB signaling pathways in human tracheal smooth muscle cells. J. Cell. Physiol. 211:759-70.
-
(2007)
J. Cell. Physiol.
, vol.211
, pp. 759-770
-
-
Liang, K.C.1
-
42
-
-
12144275863
-
Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-kappaB in IL-1beta-induced VCAM-1 expression in human tracheal smooth muscle cells
-
Wang C-C, et al. (2005) Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-kappaB in IL-1beta-induced VCAM-1 expression in human tracheal smooth muscle cells. Am. J. Lung Cell. Mol. Physiol. 288: L227-37.
-
(2005)
Am. J. Lung Cell. Mol. Physiol.
, vol.288
-
-
Wang, C.-C.1
-
43
-
-
0035718766
-
Human endotoxemia activates p38 MAP kinase and p42/44 MAP kinase, but not c-Jun N-terminal kinase
-
van den Blink B, et al. (2001) Human endotoxemia activates p38 MAP kinase and p42/44 MAP kinase, but not c-Jun N-terminal kinase. Mol. Med. 7:755-60.
-
(2001)
Mol. Med.
, vol.7
, pp. 755-760
-
-
van den Blink, B.1
-
44
-
-
33947597084
-
Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
-
Jope R, Yuskaitis C, Beurel E. (2007) Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem. Res. 32:577-595.
-
(2007)
Neurochem. Res.
, vol.32
, pp. 577-595
-
-
Jope, R.1
Yuskaitis, C.2
Beurel, E.3
-
45
-
-
58249117791
-
Glycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice
-
Zhang P, Katz J, Michalek SM. (2009) Glycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice. Mol. Immunol. 46:677-87.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 677-687
-
-
Zhang, P.1
Katz, J.2
Michalek, S.M.3
-
46
-
-
73149097234
-
Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)
-
Beurel E, Michalek SM, Jope RS. (2009) Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). Trends Immunol. 31:24-31.
-
(2009)
Trends Immunol
, vol.31
, pp. 24-31
-
-
Beurel, E.1
Michalek, S.M.2
Jope, R.S.3
-
47
-
-
2442691688
-
Activation of the STAT pathway in acute lung injury
-
Severgnini M, et al. (2004) Activation of the STAT pathway in acute lung injury. Am. J. Lung Cell. Mol. Physiol. 286:L1282-92.
-
(2004)
Am. J. Lung Cell. Mol. Physiol.
, vol.286
-
-
Severgnini, M.1
-
48
-
-
44949214708
-
Src kinase-targeted antiinflammatory activity of davallialactone from Inonotus xeranticus in lipopolysaccharide-activated RAW264.7 cells
-
Lee YG, et al. (2008) Src kinase-targeted antiinflammatory activity of davallialactone from Inonotus xeranticus in lipopolysaccharide-activated RAW264.7 cells. Br. J. Pharmacol. 154:852-63.
-
(2008)
Br. J. Pharmacol.
, vol.154
, pp. 852-863
-
-
Lee, Y.G.1
-
49
-
-
62749113471
-
Tyrosine kinases and inflammatory signalling
-
Page TH, Smolinska M, Gillespie J, Urbaniak AM, Foxwell BM. (2009) Tyrosine kinases and inflammatory signalling. Curr. Mol. Med. 9:69-85.
-
(2009)
Curr. Mol. Med.
, vol.9
, pp. 69-85
-
-
Page, T.H.1
Smolinska, M.2
Gillespie, J.3
Urbaniak, A.M.4
Foxwell, B.M.5
|