-
1
-
-
0036885057
-
Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation
-
Ashikawa K, Majumdar S, Banerjee S, Bharti AC, Shishodia S, Aggarwal BB (2002). Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation. J Immunol 169: 6490-6497.
-
(2002)
J Immunol
, vol.169
, pp. 6490-6497
-
-
Ashikawa, K.1
Majumdar, S.2
Banerjee, S.3
Bharti, A.C.4
Shishodia, S.5
Aggarwal, B.B.6
-
2
-
-
33750570883
-
Negative regulators of toll-like receptor 4-mediated macrophage inflammatory response
-
Butchar JP, Parsa KV, Marsh CB, Tridandapani S (2006). Negative regulators of toll-like receptor 4-mediated macrophage inflammatory response. Curr Pharm Des 12: 4143-4153.
-
(2006)
Curr Pharm Des
, vol.12
, pp. 4143-4153
-
-
Butchar, J.P.1
Parsa, K.V.2
Marsh, C.B.3
Tridandapani, S.4
-
3
-
-
0034705758
-
In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa
-
Cho JY, Baik KU, Jung JH, Park MH (2000). In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa. Eur J Pharmacol 398: 399-407.
-
(2000)
Eur J Pharmacol
, vol.398
, pp. 399-407
-
-
Cho, J.Y.1
Baik, K.U.2
Jung, J.H.3
Park, M.H.4
-
4
-
-
0346728753
-
Cynaropicrin, a sesquiterpene lactone, as a new strong regulator of CD29 and CD98 functions
-
Cho JY, Kim AR, Joo HG, Kim BH, Rhee MH, Yoo ES et al. (2004a). Cynaropicrin, a sesquiterpene lactone, as a new strong regulator of CD29 and CD98 functions. Biochem Biophys Res Commun 313: 954-961.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 954-961
-
-
Cho, J.Y.1
Kim, A.R.2
Joo, H.G.3
Kim, B.H.4
Rhee, M.H.5
Yoo, E.S.6
-
5
-
-
0035115787
-
Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation
-
Cho JY, Park J, Kim PS, Yoo ES, Baik KU, Park MH (2001). Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation. Biol Pharm Bull 24: 167-171.
-
(2001)
Biol Pharm Bull
, vol.24
, pp. 167-171
-
-
Cho, J.Y.1
Park, J.2
Kim, P.S.3
Yoo, E.S.4
Baik, K.U.5
Park, M.H.6
-
6
-
-
1442358039
-
Differential effect of phosphodiesterase IV inhibitor RP73401 on various inflammatory and immune responses relevent to rheumatoid arthritis
-
Cho JY, Park JS, Baik KU, Lee JG, Kim HP, Yoo ES et al. (2004b). Differential effect of phosphodiesterase IV inhibitor RP73401 on various inflammatory and immune responses relevent to rheumatoid arthritis. Pharmacol Res 49: 423-431.
-
(2004)
Pharmacol Res
, vol.49
, pp. 423-431
-
-
Cho, J.Y.1
Park, J.S.2
Baik, K.U.3
Lee, J.G.4
Kim, H.P.5
Yoo, E.S.6
-
7
-
-
33750989362
-
2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl) -2-((6-(4-(2-hydroxyethyl)-1-piperazinyl))-2-methyl-4-pyrimidinyl)amino))-1, 3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor
-
Das J, Chen P, Norris D, Padmanabha R, Lin J, Moquin RV et al. (2006). 2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl) -2-((6-(4-(2-hydroxyethyl)-1-piperazinyl))-2-methyl-4-pyrimidinyl)amino))-1, 3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. J Med Chem 49: 6819-6832.
-
(2006)
J Med Chem
, vol.49
, pp. 6819-6832
-
-
Das, J.1
Chen, P.2
Norris, D.3
Padmanabha, R.4
Lin, J.5
Moquin, R.V.6
-
8
-
-
14744302363
-
NF-kappa B - a target in the inflammation of bone destruction
-
Doggrell SA (2005). NF-kappa B - a target in the inflammation of bone destruction. Expert Opin Ther Targets 9: 191-193.
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 191-193
-
-
Doggrell, S.A.1
-
9
-
-
33645130179
-
A beta-D-glucan isolated from the fruiting bodies of Hericium erinaceus and its aqueous conformation
-
Dong Q, Jia LM, Fang JN (2006). A beta-D-glucan isolated from the fruiting bodies of Hericium erinaceus and its aqueous conformation. Carbohydr Res 341: 791-795.
-
(2006)
Carbohydr Res
, vol.341
, pp. 791-795
-
-
Dong, Q.1
Jia, L.M.2
Fang, J.N.3
-
10
-
-
20044381138
-
Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms
-
Evans SE, Hahn PY, McCann F, Kottom TJ, Pavlovic ZV, Limper AH (2005). Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms. Am J Respir Cell Mol Biol 32: 490-497.
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, pp. 490-497
-
-
Evans, S.E.1
Hahn, P.Y.2
McCann, F.3
Kottom, T.J.4
Pavlovic, Z.V.5
Limper, A.H.6
-
11
-
-
70449564383
-
The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis
-
Fishman P, Bar-Yehuda S, Madi L, Rath-Wolfson L, Ochaion A, Cohen S et al. (2006). The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis. Arthritis Res Ther 8: R33.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Fishman, P.1
Bar-Yehuda, S.2
Madi, L.3
Rath-Wolfson, L.4
Ochaion, A.5
Cohen, S.6
-
12
-
-
0035955729
-
Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
-
Garcia-Pineres AJ, Castro V, Mora G, Schmidt TJ, Strunck E, Pahl HL et al. (2001). Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J Biol Chem 276: 39713-39720.
-
(2001)
J Biol Chem
, vol.276
, pp. 39713-39720
-
-
Garcia-Pineres, A.J.1
Castro, V.2
Mora, G.3
Schmidt, T.J.4
Strunck, E.5
Pahl, H.L.6
-
13
-
-
5344222677
-
Effects of a redox-active agent on lymphocyte activation and early gene expression patterns
-
Hardy K, Hunt NH (2004). Effects of a redox-active agent on lymphocyte activation and early gene expression patterns. Free Radic Biol Med 37: 1550-1563.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1550-1563
-
-
Hardy, K.1
Hunt, N.H.2
-
14
-
-
33748490486
-
The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages
-
Hatziieremia S, Gray AI, Ferro VA, Paul A, Plevin R (2006). The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages. Br J Pharmacol 149: 188-198.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 188-198
-
-
Hatziieremia, S.1
Gray, A.I.2
Ferro, V.A.3
Paul, A.4
Plevin, R.5
-
15
-
-
0346340070
-
In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges
-
Hong S, Kim SH, Rhee MH, Kim AR, Jung JH, Chun T et al. (2003). In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges. Naunyn Schmiedebergs Arch Pharmacol 368: 448-456.
-
(2003)
Naunyn Schmiedebergs Arch Pharmacol
, vol.368
, pp. 448-456
-
-
Hong, S.1
Kim, S.H.2
Rhee, M.H.3
Kim, A.R.4
Jung, J.H.5
Chun, T.6
-
16
-
-
17944402626
-
Pi 3-kinase and its up- and down-stream modulators as potential targets for the treatment of type II diabetes
-
Jiang G, Zhang BB (2002). Pi 3-kinase and its up- and down-stream modulators as potential targets for the treatment of type II diabetes. Front Biosci 7: d903-d907.
-
(2002)
Front Biosci
, vol.7
-
-
Jiang, G.1
Zhang, B.B.2
-
17
-
-
33749533244
-
Inhibitory effect of curcumin on nitric oxide production from lipopolysaccharide-activated primary microglia
-
Jung KK, Lee HS, Cho JY, Shin WC, Rhee MH, Kim TG et al. (2006). Inhibitory effect of curcumin on nitric oxide production from lipopolysaccharide-activated primary microglia. Life Sci 79: 2022-2031.
-
(2006)
Life Sci
, vol.79
, pp. 2022-2031
-
-
Jung, K.K.1
Lee, H.S.2
Cho, J.Y.3
Shin, W.C.4
Rhee, M.H.5
Kim, T.G.6
-
18
-
-
4544357992
-
Anti-inflammatory cyathane diterpenoids from Sarcodon scabrosus
-
Kamo T, Imura Y, Hagio T, Makabe H, Shibata H, Hirota M (2004). Anti-inflammatory cyathane diterpenoids from Sarcodon scabrosus. Biosci Biotechnol Biochem 68: 1362-1365.
-
(2004)
Biosci Biotechnol Biochem
, vol.68
, pp. 1362-1365
-
-
Kamo, T.1
Imura, Y.2
Hagio, T.3
Makabe, H.4
Shibata, H.5
Hirota, M.6
-
19
-
-
0346850850
-
Oxidative stress reprograms lipopolysaccharide signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line
-
Khadaroo RG, Kapus A, Powers KA, Cybulsky MI, Marshall JC, Rotstein OD (2003). Oxidative stress reprograms lipopolysaccharide signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line. J Biol Chem 278: 47834-47841.
-
(2003)
J Biol Chem
, vol.278
, pp. 47834-47841
-
-
Khadaroo, R.G.1
Kapus, A.2
Powers, K.A.3
Cybulsky, M.I.4
Marshall, J.C.5
Rotstein, O.D.6
-
20
-
-
33747347753
-
Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells
-
Kim HG, Shrestha B, Lim SY, Yoon DH, Chang WC, Shin DJ et al. (2006). Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells. Eur J Pharmacol 545: 192-199.
-
(2006)
Eur J Pharmacol
, vol.545
, pp. 192-199
-
-
Kim, H.G.1
Shrestha, B.2
Lim, S.Y.3
Yoon, D.H.4
Chang, W.C.5
Shin, D.J.6
-
21
-
-
0345016388
-
Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia
-
Kim HY, Park EJ, Joe EH, Jou I (2003). Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J Immunol 171: 6072-6079.
-
(2003)
J Immunol
, vol.171
, pp. 6072-6079
-
-
Kim, H.Y.1
Park, E.J.2
Joe, E.H.3
Jou, I.4
-
22
-
-
41349108242
-
The mechanism of anti-platelet activity of davallialactone: Involvement of intracellular calcium ions, extracellular signal-regulated kinase 2 and p38 mitogen-activated protein kinase
-
Kim SD, Lee IK, Lee WM, Cho JY, Park HJ, Oh JW et al. (2008). The mechanism of anti-platelet activity of davallialactone: involvement of intracellular calcium ions, extracellular signal-regulated kinase 2 and p38 mitogen-activated protein kinase. Eur J Pharmacol 584: 361-367.
-
(2008)
Eur J Pharmacol
, vol.584
, pp. 361-367
-
-
Kim, S.D.1
Lee, I.K.2
Lee, W.M.3
Cho, J.Y.4
Park, H.J.5
Oh, J.W.6
-
23
-
-
33846512747
-
Ergosterol peroxide from an edible mushroom suppresses inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells
-
Kobori M, Yoshida M, Ohnishi-Kameyama M, Shinmoto H (2007). Ergosterol peroxide from an edible mushroom suppresses inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells. Br J Pharmacol 150: 209-219.
-
(2007)
Br J Pharmacol
, vol.150
, pp. 209-219
-
-
Kobori, M.1
Yoshida, M.2
Ohnishi-Kameyama, M.3
Shinmoto, H.4
-
24
-
-
38449099025
-
Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury
-
Lee HS, Moon C, Lee HW, Park EM, Cho MS, Kang JL (2007). Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury. J Immunol 179: 7001-7011.
-
(2007)
J Immunol
, vol.179
, pp. 7001-7011
-
-
Lee, H.S.1
Moon, C.2
Lee, H.W.3
Park, E.M.4
Cho, M.S.5
Kang, J.L.6
-
25
-
-
33644922664
-
Hispidin derivatives from the mushroom Inonotus xeranticus and their antioxidant activity
-
Lee IK, Seok SJ, Kim WK, Yun BS (2006). Hispidin derivatives from the mushroom Inonotus xeranticus and their antioxidant activity. J Nat Prod 69: 299-301.
-
(2006)
J Nat Prod
, vol.69
, pp. 299-301
-
-
Lee, I.K.1
Seok, S.J.2
Kim, W.K.3
Yun, B.S.4
-
26
-
-
33644976739
-
Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity
-
Lee IK, Yun BS (2006). Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity. Bioorg Med Chem Lett 16: 2376-2379.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 2376-2379
-
-
Lee, I.K.1
Yun, B.S.2
-
27
-
-
24944549093
-
The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4
-
Lee JY, Lowell CA, Lemay DG, Youn HS, Rhee SH, Sohn KH et al. (2005). The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4. Biochem Pharmacol 70: 1231-1240.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 1231-1240
-
-
Lee, J.Y.1
Lowell, C.A.2
Lemay, D.G.3
Youn, H.S.4
Rhee, S.H.5
Sohn, K.H.6
-
28
-
-
27944487579
-
Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages
-
Leu TH, Charoenfuprasert S, Yen CK, Fan CW, Maa MC (2006). Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages. Mol Immunol 43: 308-316.
-
(2006)
Mol Immunol
, vol.43
, pp. 308-316
-
-
Leu, T.H.1
Charoenfuprasert, S.2
Yen, C.K.3
Fan, C.W.4
Maa, M.C.5
-
29
-
-
25644438318
-
Antiinflammatory and immunomodulating properties of fungal metabolites
-
Lull C, Wichers HJ, Savelkoul HF (2005). Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm 2005: 63-80.
-
(2005)
Mediators Inflamm
, vol.2005
, pp. 63-80
-
-
Lull, C.1
Wichers, H.J.2
Savelkoul, H.F.3
-
30
-
-
0042972586
-
Controlled modulation of inflammatory, stress and apoptotic responses in macrophages
-
Malyshev IY, Shnyra A (2003). Controlled modulation of inflammatory, stress and apoptotic responses in macrophages. Curr Drug Targets Immune Endocr Metabol Disord 3: 1-22.
-
(2003)
Curr Drug Targets Immune Endocr Metabol Disord
, vol.3
, pp. 1-22
-
-
Malyshev, I.Y.1
Shnyra, A.2
-
31
-
-
0034716766
-
Structure elucidation of clavilactone D: An inhibitor of protein tyrosine kinases
-
Merlini L, Nasini G, Scaglioni L, Cassinelli G, Lanzi C (2000). Structure elucidation of clavilactone D: an inhibitor of protein tyrosine kinases. Phytochemistry 53: 1039-1041.
-
(2000)
Phytochemistry
, vol.53
, pp. 1039-1041
-
-
Merlini, L.1
Nasini, G.2
Scaglioni, L.3
Cassinelli, G.4
Lanzi, C.5
-
32
-
-
33746862576
-
Naturally occurring NF-kappaB inhibitors
-
Nam NH (2006). Naturally occurring NF-kappaB inhibitors. Mini Rev Med Chem 6: 945-951.
-
(2006)
Mini Rev Med Chem
, vol.6
, pp. 945-951
-
-
Nam, N.H.1
-
33
-
-
0035895375
-
New responsibilities for the PI3K regulatory subunit p85 alpha
-
Okkenhaug K, Vanhaesebroeck B (2001). New responsibilities for the PI3K regulatory subunit p85 alpha. Sci STKE 2001: PE1.
-
(2001)
Sci STKE
, vol.2001
-
-
Okkenhaug, K.1
Vanhaesebroeck, B.2
-
34
-
-
0036748197
-
Pulmonary innate immune proteins and receptors that interact with gram-positive bacterial ligands
-
Palaniyar N, Nadesalingam J, Reid KB (2002). Pulmonary innate immune proteins and receptors that interact with gram-positive bacterial ligands. Immunobiology 205: 575-594.
-
(2002)
Immunobiology
, vol.205
, pp. 575-594
-
-
Palaniyar, N.1
Nadesalingam, J.2
Reid, K.B.3
-
35
-
-
0035813230
-
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity
-
Park J, Hill MM, Hess D, Brazil DP, Hofsteenge J, Hemmings BA (2001). Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity. J Biol Chem 276: 37459-37471.
-
(2001)
J Biol Chem
, vol.276
, pp. 37459-37471
-
-
Park, J.1
Hill, M.M.2
Hess, D.3
Brazil, D.P.4
Hofsteenge, J.5
Hemmings, B.A.6
-
36
-
-
0029915543
-
Inhibition of TNF-alpha expression by adenosine: Role of A3 adenosine receptors
-
Sajjadi FG, Takabayashi K, Foster AC, Domingo RC, Firestein GS (1996). Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors. J Immunol 156: 3435-3442.
-
(1996)
J Immunol
, vol.156
, pp. 3435-3442
-
-
Sajjadi, F.G.1
Takabayashi, K.2
Foster, A.C.3
Domingo, R.C.4
Firestein, G.S.5
-
37
-
-
35548985405
-
Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages
-
Smolinska MJ, Horwood NJ, Page TH, Smallie T, Foxwell BM (2008). Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages. Mol Immunol 45: 990-1000.
-
(2008)
Mol Immunol
, vol.45
, pp. 990-1000
-
-
Smolinska, M.J.1
Horwood, N.J.2
Page, T.H.3
Smallie, T.4
Foxwell, B.M.5
-
38
-
-
0037457313
-
Enzymatic hydrolysis of water-soluble wheat arabinoxylan. 1. Synergy between alpha-L- arabinofuranosidases, endo-1,4-beta-xylanases, and beta-xylosidase activities
-
Sorensen HR, Meyer AS, Pedersen S (2003). Enzymatic hydrolysis of water-soluble wheat arabinoxylan. 1. Synergy between alpha-L- arabinofuranosidases, endo-1,4-beta-xylanases, and beta-xylosidase activities. Biotechnol Bioeng 81: 726-731.
-
(2003)
Biotechnol Bioeng
, vol.81
, pp. 726-731
-
-
Sorensen, H.R.1
Meyer, A.S.2
Pedersen, S.3
-
39
-
-
33947545753
-
Structures, biogenesis, and biological activities of pyrano(4,3-c) isochromen-4-one derivatives from the Fungus Phellinus igniarius
-
Wang Y, Shang XY, Wang SJ, Mo SY, Li S, Yang YC et al. (2007). Structures, biogenesis, and biological activities of pyrano(4,3-c) isochromen-4-one derivatives from the Fungus Phellinus igniarius. J Nat Prod 70: 296-299.
-
(2007)
J Nat Prod
, vol.70
, pp. 296-299
-
-
Wang, Y.1
Shang, X.Y.2
Wang, S.J.3
Mo, S.Y.4
Li, S.5
Yang, Y.C.6
-
40
-
-
33744548730
-
Signal transduction of inflammatory cytokines and tumor development
-
Yoshimura A (2006). Signal transduction of inflammatory cytokines and tumor development. Cancer Sci 97: 439-447.
-
(2006)
Cancer Sci
, vol.97
, pp. 439-447
-
-
Yoshimura, A.1
|