Glycogen synthase kinase-3β (GSK3β) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice

Molecular Immunology

Volumn 46, Issue 4, 2009, Pages 677-687

  Zhang, Ping ^a   Katz, Jenny ^a   Michalek, Suzanne M ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

F. tularensis; GSK3 ; IFN ; Inflammation

Indexed keywords

2',3' 6 BROMOINDIRUBIN 3' OXIME; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 6; LITHIUM CHLORIDE; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; FRANCISELLA TULARENSIS; INFLAMMATION; INTERFERON PRODUCTION; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SURVIVAL; TULAREMIA;

ANIMALS; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DISEASE MODELS, ANIMAL; FEMALE; FRANCISELLA TULARENSIS; GLYCOGEN SYNTHASE KINASE 3; INTERLEUKIN-10; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-6; LITHIUM CHLORIDE; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; PHOSPHORYLATION; TOLL-LIKE RECEPTOR 2; TULAREMIA; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; FRANCISELLA; FRANCISELLA TULARENSIS; MURINAE; MUS;

EID: 58249117791     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.08.281     Document Type: Article

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