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ChemMedChem

Volumn 6, Issue 8, 2011, Pages 1340-1346

Identification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABA A Receptors

(5) Gavande, Navnath a Karim, Nasiara a Johnston, Graham A R b Hanrahan, Jane R a Chebib, Mary a

a UNIVERSITY OF SYDNEY (Australia)

b University of Sydney (Australia)

Author keywords

Central nervous system (CNS) disorders; Drug discovery; GABA receptors; Isoflavones; Two electrode voltage clamp method

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR; FLUMAZENIL; ISOFLAVONE; TETRAHYDROPYRAN DERIVATIVE;

ALKYLATION; BINDING AFFINITY; CENTRAL NERVOUS SYSTEM DISEASE; CROSS COUPLING REACTION; CYCLIZATION; DRUG ACTIVITY; DRUG SYNTHESIS; HYDROGEN BOND; MICROWAVE IRRADIATION; NOTE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; FLUMAZENIL; GABA MODULATORS; HUMANS; ISOFLAVONES; OOCYTES; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS;

EID: 79960732322 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100120 Document Type: Note

Times cited : (20)

References (43)

1
- 77951697766
- Eds: W.J. Lennarz, M.D. Lane), Elsevier, Oxford
- F. Minier, E. Sigel in Encyclopedia of Biological Chemistry, vol.2, (Eds: W.J. Lennarz, M.D. Lane), Elsevier, Oxford, 2004, pp.562-566;
- (2004) Encyclopedia of Biological Chemistry , vol.2 , pp. 562-566
- Minier, F.¹ Sigel, E.²

2
- 0025596894
- A. B. Young, D. Chu, Drug Dev. Res. 1990, 21, 161-167.
- (1990) Drug Dev. Res. , vol.21 , pp. 161-167
- Young, A.B.¹ Chu, D.²

3
- 20044396748
- G. A. R. Johnston, Curr. Pharm. Des. 2005, 11, 1867-1885;
- (2005) Curr. Pharm. Des. , vol.11 , pp. 1867-1885
- Johnston, G.A.R.¹

4
- 0034692175
- M. Chebib, G. A. R. Johnston, J. Med. Chem. 2000, 43, 1427-1447;
- (2000) J. Med. Chem. , vol.43 , pp. 1427-1447
- Chebib, M.¹ Johnston, G.A.R.²

5
- 0033982996
- J. Bormann, Trends Pharmacol. Sci. 2000, 21, 16-19.
- (2000) Trends Pharmacol. Sci. , vol.21 , pp. 16-19
- Bormann, J.¹

6
- 0038178996
- P. J. Whiting, Drug Discovery Today 2003, 8, 445-450;
- (2003) Drug Discovery Today , vol.8 , pp. 445-450
- Whiting, P.J.¹

7
- 0029670123
- R. M. McKernan, P. J. Whiting, Trends Neurosci. 1996, 19, 139-143.
- (1996) Trends Neurosci. , vol.19 , pp. 139-143
- McKernan, R.M.¹ Whiting, P.J.²

8
- 30844456191
- U. Rudolph, H. Möhler, Curr. Opin. Pharmacol. 2006, 6, 18-23;
- (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 18-23
- Rudolph, U.¹ Möhler, H.²

9
- 33750511497
- W. Sieghart, Drugs Future 2006, 31, 685-694.
- (2006) Drugs Future , vol.31 , pp. 685-694
- Sieghart, W.¹

10
- 30844442386
- P. J. Whiting, Curr. Opin. Pharmacol. 2006, 6, 24-29;
- (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 24-29
- Whiting, P.J.¹

11
- 0031685608
- A. D. Fraser, Ther. Drug Monit. 1998, 20, 481-489.
- (1998) Ther. Drug Monit. , vol.20 , pp. 481-489
- Fraser, A.D.¹

12
- 13444259735
- H. Möhler, U. Rudolph, Drug Discovery Today Ther. Strategies 2004, 1, 117-123;
- (2004) Drug Discovery Today Ther. Strategies , vol.1 , pp. 117-123
- Möhler, H.¹ Rudolph, U.²

13
- 0035714672
- E. Sigel, R. H. Dodd, Drugs Future 2001, 26, 1191-1197.
- (2001) Drugs Future , vol.26 , pp. 1191-1197
- Sigel, E.¹ Dodd, R.H.²

14
- 79954555973
- J. R. Hanrahan, M. Chebib, G. A. R. Johnston, Br. J. Pharmacol. 2011, 163, 234-245;
- (2011) Br. J. Pharmacol. , vol.163 , pp. 234-245
- Hanrahan, J.R.¹ Chebib, M.² Johnston, G.A.R.³

15
- 71749090848
- K. N. Mewett, S. P. Fernandez, A. K. Pasricha, A. Pong, S. O. Devenish, D. E. Hibbs, M. Chebib, G. A. R. Johnston, J. R. Hanrahan, Bioorg. Med. Chem. 2009, 17, 7156-7173;
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 7156-7173
- Mewett, K.N.¹ Fernandez, S.P.² Pasricha, A.K.³ Pong, A.⁴ Devenish, S.O.⁵ Hibbs, D.E.⁶ Chebib, M.⁷ Johnston, G.A.R.⁸ Hanrahan, J.R.⁹

16
- 50949103149
- S. P. Fernandez, K. N. Mewett, J. R. Hanrahan, M. Chebib, G. A. R. Johnston, Neuropharmacology 2008, 55, 900-907;
- (2008) Neuropharmacology , vol.55 , pp. 900-907
- Fernandez, S.P.¹ Mewett, K.N.² Hanrahan, J.R.³ Chebib, M.⁴ Johnston, G.A.R.⁵

17
- 17544370365
- B. J. Hall, M. Chebib, J. R. Hanrahan, G. A. R. Johnston, Eur. J. Pharmacol. 2005, 512, 97-104;
- (2005) Eur. J. Pharmacol. , vol.512 , pp. 97-104
- Hall, B.J.¹ Chebib, M.² Hanrahan, J.R.³ Johnston, G.A.R.⁴

18
- 4644281655
- B. J. Hall, M. Chebib, J. R. Hanrahan, G. A. R. Johnston, Eur. J. Pharmacol. 2004, 491, 1-8;
- (2004) Eur. J. Pharmacol. , vol.491 , pp. 1-8
- Hall, B.J.¹ Chebib, M.² Hanrahan, J.R.³ Johnston, G.A.R.⁴

19
- 0038342007
- J. R. Hanrahan, M. Chebib, N. L. M. Davucheron, B. J. Hall, G. A. R. Johnston, Bioorg. Med. Chem. Lett. 2003, 13, 2281-2284.
- (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 2281-2284
- Hanrahan, J.R.¹ Chebib, M.² Davucheron, N.L.M.³ Hall, B.J.⁴ Johnston, G.A.R.⁵

20
- 0031426786
- J. Ai, K. Dekermendjian, X. Wang, M. Nielsen, M-R. Witt, Drug Dev. Res. 1997, 41, 99-106.
- (1997) Drug Dev. Res. , vol.41 , pp. 99-106
- Ai, J.¹ Dekermendjian, K.² Wang, X.³ Nielsen, M.⁴ Witt, M.-R.⁵

21
- 26844489782
- F. Wang, M. S. YanHuen, S. Tsang, H. Xue, Curr. Drug Targets: CNS Neurol. Disord. 2005, 4, 575-585;
- (2005) Curr. Drug Targets: CNS Neurol. Disord. , vol.4 , pp. 575-585
- Wang, F.¹ YanHuen, M.S.² Tsang, S.³ Xue, H.⁴

22
- 0036674897
- M. Marder, A. C. Paladini, Curr. Top. Med. Chem. 2002, 2, 853-867;
- (2002) Curr. Top. Med. Chem. , vol.2 , pp. 853-867
- Marder, M.¹ Paladini, A.C.²

23
- 0037068477
- P. Kahnberg, E. Lager, C. Rosenberg, J. Schougaard, L. Camet, O. Sterner, E. Ø. Nielsen, M. Nielsen, T. Liljefors, J. Med. Chem. 2002, 45, 4188-4201;
- (2002) J. Med. Chem. , vol.45 , pp. 4188-4201
- Kahnberg, P.¹ Lager, E.² Rosenberg, C.³ Schougaard, J.⁴ Camet, L.⁵ Sterner, O.⁶ Nielsen, E.⁷ Nielsen, M.⁸ Liljefors, T.⁹

24
- 0035082436
- M. Marder, G. Estiú, L. Blanch, H. Viola, C. Wasowski, J. Medina, A. Paladini, Bioorg. Med. Chem. 2001, 9, 323-335;
- (2001) Bioorg. Med. Chem. , vol.9 , pp. 323-335
- Marder, M.¹ Estiú, G.² Blanch, L.³ Viola, H.⁴ Wasowski, C.⁵ Medina, J.⁶ Paladini, A.⁷

25
- 0032725338
- K. Dekermendjian, P. Kahnberg, M-R. Witt, O. Sterner, M. Nielsen, T. Liljefors, J. Med. Chem. 1999, 42, 4343-4350.
- (1999) J. Med. Chem. , vol.42 , pp. 4343-4350
- Dekermendjian, K.¹ Kahnberg, P.² Witt, M.-R.³ Sterner, O.⁴ Nielsen, M.⁵ Liljefors, T.⁶

26
- 34347339670
- W. Wuttke, H. Jarry, D. Seidlová-Wuttke, Ageing Res. Rev. 2007, 6, 150-188;
- (2007) Ageing Res. Rev. , vol.6 , pp. 150-188
- Wuttke, W.¹ Jarry, H.² Seidlová-Wuttke, D.³

27
- 0030810999
- R. Civitelli, Calcif. Tissue Int. 1997, 61, S12-14.
- (1997) Calcif. Tissue Int. , vol.61
- Civitelli, R.¹

28
- 36249025809
- K. A. Jackman, O. L. Woodman, C. G. Sobey, Curr. Med. Chem. 2007, 14, 2824-2830.
- (2007) Curr. Med. Chem. , vol.14 , pp. 2824-2830
- Jackman, K.A.¹ Woodman, O.L.² Sobey, C.G.³

29
- 0035027736
- K. Morito, T. Hirose, J. Kinjo, T. Hirakawa, M. Okawa, T. Nohara, S. Ogawa, S. Inoue, M. Muramatsu, Y. Masamune, Biol. Pharm. Bull. 2001, 24, 351-356.
- (2001) Biol. Pharm. Bull. , vol.24 , pp. 351-356
- Morito, K.¹ Hirose, T.² Kinjo, J.³ Hirakawa, T.⁴ Okawa, M.⁵ Nohara, T.⁶ Ogawa, S.⁷ Inoue, S.⁸ Muramatsu, M.⁹ Masamune, Y.¹⁰

30
- 0021049851
- K. C. Luk, L. Stern, M. Weigle, R. A. O'Brien, N. Spirst, J. Nat. Prod. 1983, 46, 852-861.
- (1983) J. Nat. Prod. , vol.46 , pp. 852-861
- Luk, K.C.¹ Stern, L.² Weigle, M.³ O'Brien, R.A.⁴ Spirst, N.⁵

31
- 3042798304
- D. V. S. Lopes, R. R. B. Caruso, N. G. Castro, P. R. R. Costa, A. J. M. daSilva, F. Noel, Eur. J. Pharmacol. 2004, 495, 87-96.
- (2004) Eur. J. Pharmacol. , vol.495 , pp. 87-96
- Lopes, D.V.S.¹ Caruso, R.R.B.² Castro, N.G.³ Costa, P.R.R.⁴ daSilva, A.J.M.⁵ Noel, F.⁶

32
- 0031593392
- E. L. Dunne, S. J. Moss, T. G. Smart, Mol. Cell. Neurosci. 1998, 12, 300-310;
- (1998) Mol. Cell. Neurosci. , vol.12 , pp. 300-310
- Dunne, E.L.¹ Moss, S.J.² Smart, T.G.³

33
- 0033528737
- R-Q. Huang, M- ;J. Fang, G. H. Dillon, Mol. Brain Res. 1999, 67, 177-183;
- (1999) Mol. Brain Res. , vol.67 , pp. 177-183
- Huang, R.-Q.¹ Fang, M.-J.² Dillon, G.H.³

34
- 4644255610
- E. L. Campbell, M. Chebib, G. A. R. Johnston, Biochem. Pharmacol. 2004, 68, 1631-1638.
- (2004) Biochem. Pharmacol. , vol.68 , pp. 1631-1638
- Campbell, E.L.¹ Chebib, M.² Johnston, G.A.R.³

35
- 71049127438
- A. Matin, N. Gavande, M. S. Kim, N. X. Yang, N. K. Salam, J. R. Hanrahan, R. H. Roubin, D. E. Hibbs, J. Med. Chem. 2009, 52, 6835-6850.
- (2009) J. Med. Chem. , vol.52 , pp. 6835-6850
- Matin, A.¹ Gavande, N.² Kim, M.S.³ Yang, N.X.⁴ Salam, N.K.⁵ Hanrahan, J.R.⁶ Roubin, R.H.⁷ Hibbs, D.E.⁸

36
- 70449367182
- R. B. Gammill, Synthesis 1979, 901-903.
- (1979) Synthesis , pp. 901-903
- Gammill, R.B.¹

37
- 33847260626
- F. X. Felpin, C. Lory, H. Sow, S. Acherar, Tetrahedron 2007, 63, 3010-3016.
- (2007) Tetrahedron , vol.63 , pp. 3010-3016
- Felpin, F.X.¹ Lory, C.² Sow, H.³ Acherar, S.⁴

38
- 34249758388
- A. Aitmambetov, L. Tsao, V. P. Khilya, Chem. Nat. Compd. 1994, 30, 304-306.
- (1994) Chem. Nat. Compd. , vol.30 , pp. 304-306
- Aitmambetov, A.¹ Tsao, L.² Khilya, V.P.³

39
- 0033623608
- R. J. Walters, S. H. Hadley, K. D. Morris, J. Amin, Nat. Neurosci. 2000, 3, 1274-1281;
- (2000) Nat. Neurosci. , vol.3 , pp. 1274-1281
- Walters, R.J.¹ Hadley, S.H.² Morris, K.D.³ Amin, J.⁴

40
- 0030693304
- E. Sigel, A. Buhr, Trends Pharmacol. Sci. 1997, 18, 425-429.
- (1997) Trends Pharmacol. Sci. , vol.18 , pp. 425-429
- Sigel, E.¹ Buhr, A.²

41
- 0141958109
- D. E. Clark, Drug Discovery Today 2003, 8, 927-933;
- (2003) Drug Discovery Today , vol.8 , pp. 927-933
- Clark, D.E.¹

42
- 0037204545
- U. Norinder, M. Haeberlein, Adv. Drug Delivery Rev. 2002, 54, 291-313;
- (2002) Adv. Drug Delivery Rev. , vol.54 , pp. 291-313
- Norinder, U.¹ Haeberlein, M.²

43
- 0033981358
- D. E. Clark, S. D. Pickett, Drug Discovery Today 2000, 5, 49-58.
- (2000) Drug Discovery Today , vol.5 , pp. 49-58
- Clark, D.E.¹ Pickett, S.D.²

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