Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABAA receptors

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 20, 2009, Pages 7156-7173

  Mewett, Kenneth N ^a   Fernandez, Sebastian P ^a   Pasricha, Anmol K ^b   Pong, Alice ^a   Devenish, Steven O ^a,b   Hibbs, David E ^b   Chebib, Mary ^b   Johnston, Graham A R ^a   Hanrahan, Jane R ^b  

^a Faculty of Medicine   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Flavan 3 ol; GABAA; Positive modulator; Structure activity

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; FLAVANOL DERIVATIVE;

ANIMAL CELL; ARTICLE; CHEMICAL MODIFICATION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION;

FLAVONOIDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 71749090848     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.08.062     Document Type: Article

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