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Volumn 9, Issue 2, 2001, Pages 323-335

Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABAA receptor complex

(7) Marder, Mariel a Estiú, Guillermina b Blanch, Luis Bruno b Viola, Haydee c Wasowski, Cristina a Medina, Jorge H c Paladini, Alejandro C a

a Instituto de Quimica y Fisicoquimica Biologicas Buenos Aires (Argentina)

b FACULTAD DE CIENCIAS EXACTAS (Argentina)

c Facultad de Medicina (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 CHLOROPHENYL) 5H PYRAZOLO[4,3 C]QUINOLIN 3 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; CARBONYL DERIVATIVE; DIAZEPAM; FLAVONE DERIVATIVE; FLAVONOID;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; LIGAND BINDING; MOLECULAR MODEL; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOSPECIFICITY; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; BENZODIAZEPINES; BINDING SITES; DIAZEPAM; DRUG INTERACTIONS; FLAVONOIDS; FLUNITRAZEPAM; LIGANDS; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA-A; SYNAPTOSOMES;

MAMMALIA;

EID: 0035082436 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(00)00250-9 Document Type: Article

Times cited : (78)

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