메뉴 건너뛰기




Volumn 21, Issue 3, 2011, Pages 175-182

Fractal analysis in a systems biology approach to cancer

Author keywords

Cancer; Carcinogenesis; Complexity; Fractal analysis; Non linear dynamics; System biology

Indexed keywords

BETA CATENIN; PROTEOME; UVOMORULIN;

EID: 79960702246     PISSN: 1044579X     EISSN: 10963650     Source Type: Journal    
DOI: 10.1016/j.semcancer.2011.04.002     Document Type: Review
Times cited : (86)

References (96)
  • 2
    • 13144305047 scopus 로고    scopus 로고
    • Systems biology for cancer
    • Khalil I.G., Hill C. Systems biology for cancer. Curr Opin Oncol 2005, 17:44-48.
    • (2005) Curr Opin Oncol , vol.17 , pp. 44-48
    • Khalil, I.G.1    Hill, C.2
  • 3
    • 46249113777 scopus 로고    scopus 로고
    • Will systems biology offer new holistic paradigms to life sciences?
    • Conti F., Valerio M.C., Zbilut J.P., Giuliani A. Will systems biology offer new holistic paradigms to life sciences?. Syst Synth Biol 2007, 1:161-165.
    • (2007) Syst Synth Biol , vol.1 , pp. 161-165
    • Conti, F.1    Valerio, M.C.2    Zbilut, J.P.3    Giuliani, A.4
  • 4
    • 2542418082 scopus 로고    scopus 로고
    • Biological complexity emerges from the ashes of genetic reductionism
    • Van Regenmortel M.H.V. Biological complexity emerges from the ashes of genetic reductionism. J Mol Recognit 2004, 17:145-148.
    • (2004) J Mol Recognit , vol.17 , pp. 145-148
    • Van Regenmortel, M.H.V.1
  • 5
    • 54849148600 scopus 로고    scopus 로고
    • The conflict between complex systems and reductionism
    • Heng H.H.Q. The conflict between complex systems and reductionism. JAMA 2008, 300(13):1580-1581.
    • (2008) JAMA , vol.300 , Issue.13 , pp. 1580-1581
    • Heng, H.H.Q.1
  • 6
    • 47949091725 scopus 로고    scopus 로고
    • The evolution of the biomedical paradigm in oncology: implications for cancer tehrapy
    • Springer, Basel, F. Colotta, A. Mantovani (Eds.)
    • Corbellini G., Preti C. The evolution of the biomedical paradigm in oncology: implications for cancer tehrapy. Targeted therapies in cancer 2008, 5-18. Springer, Basel. F. Colotta, A. Mantovani (Eds.).
    • (2008) Targeted therapies in cancer , pp. 5-18
    • Corbellini, G.1    Preti, C.2
  • 7
    • 84857110883 scopus 로고    scopus 로고
    • A rather negative judgment about the methodological foundations of cancer research was made by Robert Weinberg
    • experiments to accumulate a huge amount of reproducible data" quoted in Leaft
    • A rather negative judgment about the methodological foundations of cancer research was made by Robert Weinberg, who expressed the view that experimental oncologists cultivate the illusion of doing " something meaningful" just because they can manage straightforward experiments to accumulate a huge amount of reproducible data" quoted in Leaft C. Why we're losing the war on cancer (and how to win it). Fortune, 2004; 149(6): 76-88.
    • who expressed the view that experimental oncologists cultivate the illusion of doing " something meaningful" just because they can manage straightforward
  • 8
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: a brief overview
    • Kitano H. Systems biology: a brief overview. Science 2002, 295:1662-1664.
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 11
    • 0034047887 scopus 로고    scopus 로고
    • Organization becomes cause in the matter
    • Strohman R. Organization becomes cause in the matter. Nat Biotechnol 2000, 18:575-576.
    • (2000) Nat Biotechnol , vol.18 , pp. 575-576
    • Strohman, R.1
  • 12
    • 85015077644 scopus 로고    scopus 로고
    • The digital code of DNA
    • Hood L., Gala D. The digital code of DNA. Nature 2003, 421:444-448.
    • (2003) Nature , vol.421 , pp. 444-448
    • Hood, L.1    Gala, D.2
  • 13
    • 5044227742 scopus 로고    scopus 로고
    • The evolution of molecular biology into systems biology
    • Westerhoff H.V., Palsson B.O. The evolution of molecular biology into systems biology. Nat Biotechnol 2004, 22:1249-1252.
    • (2004) Nat Biotechnol , vol.22 , pp. 1249-1252
    • Westerhoff, H.V.1    Palsson, B.O.2
  • 14
    • 33845313946 scopus 로고    scopus 로고
    • The question of questions: what is a gene? Comments on Rolston and Griffiths & Stotz
    • Moss L. The question of questions: what is a gene? Comments on Rolston and Griffiths & Stotz. Theor Med Bioeth 2006, 27(6):523-534.
    • (2006) Theor Med Bioeth , vol.27 , Issue.6 , pp. 523-534
    • Moss, L.1
  • 15
    • 37349057040 scopus 로고    scopus 로고
    • Claude Bernard, the first systems biologist, and the future of physiology
    • Noble D. Claude Bernard, the first systems biologist, and the future of physiology. Exp Physiol 2008, 93:16-26.
    • (2008) Exp Physiol , vol.93 , pp. 16-26
    • Noble, D.1
  • 16
    • 0034073870 scopus 로고    scopus 로고
    • Redefining priorities in gene-based drug discovery
    • Huang S. Redefining priorities in gene-based drug discovery. Nat Biotechnol 2000, 18:471-472.
    • (2000) Nat Biotechnol , vol.18 , pp. 471-472
    • Huang, S.1
  • 17
    • 0035320245 scopus 로고    scopus 로고
    • It takes a tissue to make a tumour: epigenetics, cancer and the microenvironment
    • Barcellos-Hoff M.H. It takes a tissue to make a tumour: epigenetics, cancer and the microenvironment. J Mammary Gland Biol Neoplasia 2001, 6(2):213-221.
    • (2001) J Mammary Gland Biol Neoplasia , vol.6 , Issue.2 , pp. 213-221
    • Barcellos-Hoff, M.H.1
  • 19
    • 84856043672 scopus 로고
    • A mathematical theory of communication
    • Shannon E.C. A mathematical theory of communication. Bell Syst Tech J 1948, 27:379-423.
    • (1948) Bell Syst Tech J , vol.27 , pp. 379-423
    • Shannon, E.C.1
  • 20
    • 0030598904 scopus 로고    scopus 로고
    • The role of the genome project in determining the gene function: insights from model organisms
    • Miklos Rubin H. The role of the genome project in determining the gene function: insights from model organisms. Cell 1996, 86:521-529.
    • (1996) Cell , vol.86 , pp. 521-529
    • Miklos, R.H.1
  • 21
    • 0019400271 scopus 로고
    • Strength and weakness of the genetic approach to the development of the nervous system
    • Stent G. Strength and weakness of the genetic approach to the development of the nervous system. Annu Rev Neurosci 1981, 4:163-194.
    • (1981) Annu Rev Neurosci , vol.4 , pp. 163-194
    • Stent, G.1
  • 22
    • 0035043343 scopus 로고    scopus 로고
    • Binding energy and the information content of some elementary biological processes
    • Ricard J. Binding energy and the information content of some elementary biological processes. C R Acad Sci Paris 2001, 324:297-304.
    • (2001) C R Acad Sci Paris , vol.324 , pp. 297-304
    • Ricard, J.1
  • 23
    • 77950575043 scopus 로고    scopus 로고
    • Canine morphology: hunting for genes and tracking mutations
    • Shearin A.L., Ostrander E.A. Canine morphology: hunting for genes and tracking mutations. PLoS Biol 2010, 8:1-6.
    • (2010) PLoS Biol , vol.8 , pp. 1-6
    • Shearin, A.L.1    Ostrander, E.A.2
  • 24
    • 0038573670 scopus 로고    scopus 로고
    • Reflecting on complexity of biological systems: Kant and beyond?
    • Van de Vijver G., Van Speybroeck L., Vandevyvere W. Reflecting on complexity of biological systems: Kant and beyond?. Acta Biotheor 2003, 51(2):101-140.
    • (2003) Acta Biotheor , vol.51 , Issue.2 , pp. 101-140
    • Van de Vijver, G.1    Van Speybroeck, L.2    Vandevyvere, W.3
  • 26
    • 0034721164 scopus 로고    scopus 로고
    • Error and attack tolerance of complex networks
    • Albert R., Jeong H., Barabasi A.L. Error and attack tolerance of complex networks. Nature 2000, 406:378-381.
    • (2000) Nature , vol.406 , pp. 378-381
    • Albert, R.1    Jeong, H.2    Barabasi, A.L.3
  • 27
    • 0036905397 scopus 로고    scopus 로고
    • What is complexity?
    • Adami C. What is complexity?. BioEssays 2002, 24:1085-1094.
    • (2002) BioEssays , vol.24 , pp. 1085-1094
    • Adami, C.1
  • 28
    • 65249128040 scopus 로고    scopus 로고
    • Biological organization and negative entropy
    • Longo G., Bailly F. Biological organization and negative entropy. J Biol Syst 2009, 17:63-96.
    • (2009) J Biol Syst , vol.17 , pp. 63-96
    • Longo, G.1    Bailly, F.2
  • 29
    • 0015951849 scopus 로고
    • Information-theoretic computational complexity
    • Chaitin G.I. Information-theoretic computational complexity. IEEE Trans Inform Theory IT-20 1974, 10-15.
    • (1974) IEEE Trans Inform Theory IT-20 , pp. 10-15
    • Chaitin, G.I.1
  • 31
    • 34247482586 scopus 로고    scopus 로고
    • Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers
    • Guo Y., Eichler G.S., Feng Y., Ingber D.E., Huang S. Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers. J Biomed Biotechnol 2006, 2006:1-11.
    • (2006) J Biomed Biotechnol , vol.2006 , pp. 1-11
    • Guo, Y.1    Eichler, G.S.2    Feng, Y.3    Ingber, D.E.4    Huang, S.5
  • 34
    • 44349162752 scopus 로고    scopus 로고
    • Transcriptome wide noise controls lineage choice in mammalian progenitor cells
    • Chang H.H., Hemberg M., Barahona M., Ingber D.E., Huang S. Transcriptome wide noise controls lineage choice in mammalian progenitor cells. Nature 2008, 453:544-547.
    • (2008) Nature , vol.453 , pp. 544-547
    • Chang, H.H.1    Hemberg, M.2    Barahona, M.3    Ingber, D.E.4    Huang, S.5
  • 35
    • 0037686112 scopus 로고    scopus 로고
    • The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster
    • Albert R., Othmer H.G. The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster. J Theor Biol 2003, 223:1-18.
    • (2003) J Theor Biol , vol.223 , pp. 1-18
    • Albert, R.1    Othmer, H.G.2
  • 37
    • 0032809387 scopus 로고    scopus 로고
    • Gene expression profiling, genetic networks, and cellular states: an integrating concept for tumorigenesis and drug discovery
    • Huang S. Gene expression profiling, genetic networks, and cellular states: an integrating concept for tumorigenesis and drug discovery. J Mol Med 1999, 77:469-480.
    • (1999) J Mol Med , vol.77 , pp. 469-480
    • Huang, S.1
  • 39
    • 34147092119 scopus 로고    scopus 로고
    • How emergence arises
    • De Haan J. How emergence arises. Ecol Compl 2006, 3:293-301.
    • (2006) Ecol Compl , vol.3 , pp. 293-301
    • De Haan, J.1
  • 40
    • 57049112129 scopus 로고    scopus 로고
    • On physicalism and downward causation in developmental and cancer biology
    • Soto A.M., Sonnenschein C., Miquel P.A. On physicalism and downward causation in developmental and cancer biology. Acta Biotheor 2008, 56(4):257-274.
    • (2008) Acta Biotheor , vol.56 , Issue.4 , pp. 257-274
    • Soto, A.M.1    Sonnenschein, C.2    Miquel, P.A.3
  • 41
    • 0035932508 scopus 로고    scopus 로고
    • Laws of form revisited
    • Denton M., Marshall C. Laws of form revisited. Nature 2001, 410:417.
    • (2001) Nature , vol.410 , pp. 417
    • Denton, M.1    Marshall, C.2
  • 43
    • 0035079377 scopus 로고    scopus 로고
    • The continuing role of morphology in the molecular age
    • Rosai J. The continuing role of morphology in the molecular age. Mod Pathol 2001, 14:258-260.
    • (2001) Mod Pathol , vol.14 , pp. 258-260
    • Rosai, J.1
  • 45
    • 0032895851 scopus 로고    scopus 로고
    • Implications for interrelationships between nuclear architecture and control of gene expression under microgravity conditions
    • Stein G.S., Van Wijnen A.J., Stein J.L., Lian J.B., Pockwinse S.H., McNeil S. Implications for interrelationships between nuclear architecture and control of gene expression under microgravity conditions. FASEB J 1999, 13:S157-S166.
    • (1999) FASEB J , vol.13
    • Stein, G.S.1    Van Wijnen, A.J.2    Stein, J.L.3    Lian, J.B.4    Pockwinse, S.H.5    McNeil, S.6
  • 46
    • 0031803268 scopus 로고    scopus 로고
    • Is cytoskeletal tension a major determinant of cell deformability in adherent endothelial cells?
    • Pourati J., Maniotis A., Speigel D., Schaffer J.L., Butler J.P., Fredberg J.J., et al. Is cytoskeletal tension a major determinant of cell deformability in adherent endothelial cells?. Am J Physiol 1998, 274:C1283-C1289.
    • (1998) Am J Physiol , vol.274
    • Pourati, J.1    Maniotis, A.2    Speigel, D.3    Schaffer, J.L.4    Butler, J.P.5    Fredberg, J.J.6
  • 47
    • 58049211966 scopus 로고    scopus 로고
    • Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
    • Wang N., Tytell J.D., Ingber D.E. Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol 2009, 10(1):75-82.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.1 , pp. 75-82
    • Wang, N.1    Tytell, J.D.2    Ingber, D.E.3
  • 50
    • 35649021357 scopus 로고    scopus 로고
    • Fractal analysis of contours of breast masses in mammograms
    • Rangayyan R.M., Nguyen T.M. Fractal analysis of contours of breast masses in mammograms. J Digit Imaging 2007, 20(3):223-237.
    • (2007) J Digit Imaging , vol.20 , Issue.3 , pp. 223-237
    • Rangayyan, R.M.1    Nguyen, T.M.2
  • 52
    • 0004240097 scopus 로고    scopus 로고
    • Birkhauser Verlag, Basel, G.A. Losa, D. Merlini, T.F. Nonnenmacher, E.R. Weibel (Eds.)
    • Fractals in biology and medicine 2002, Birkhauser Verlag, Basel. G.A. Losa, D. Merlini, T.F. Nonnenmacher, E.R. Weibel (Eds.).
    • (2002) Fractals in biology and medicine
  • 53
    • 0034660890 scopus 로고    scopus 로고
    • Fractals and cancer
    • Baish J.W., Jain R.K. Fractals and cancer. Cancer Res 2000, 60:3683-3688.
    • (2000) Cancer Res , vol.60 , pp. 3683-3688
    • Baish, J.W.1    Jain, R.K.2
  • 54
    • 0030909412 scopus 로고    scopus 로고
    • Fractals in pathology
    • Cross S.S. Fractals in pathology. J Pathol 1997, 182:1-8.
    • (1997) J Pathol , vol.182 , pp. 1-8
    • Cross, S.S.1
  • 55
    • 0029162170 scopus 로고
    • Fractal and integer-dimensional analysis of pigmented skin lesions
    • Cross S.S., McDonagh A.J.G., Stephenson T.J., et al. Fractal and integer-dimensional analysis of pigmented skin lesions. Am J Dermatol 1995, 17:374-378.
    • (1995) Am J Dermatol , vol.17 , pp. 374-378
    • Cross, S.S.1    McDonagh, A.J.G.2    Stephenson, T.J.3
  • 56
    • 0026520067 scopus 로고
    • Shape analysis for classification of malignant melanoma
    • Claridge E., Hall P.N., Keefe M., et al. Shape analysis for classification of malignant melanoma. J Biomed Eng 1992, 14:229-324.
    • (1992) J Biomed Eng , vol.14 , pp. 229-324
    • Claridge, E.1    Hall, P.N.2    Keefe, M.3
  • 57
    • 0001489531 scopus 로고
    • Scale-invariant behavior and vascular network formation in normal and tumour tissue
    • Gazit Y., Berk D.A., Leunig M., Baxter L.T., Jain R.K. Scale-invariant behavior and vascular network formation in normal and tumour tissue. Phys Rev Lett 1995, 75:2428-2431.
    • (1995) Phys Rev Lett , vol.75 , pp. 2428-2431
    • Gazit, Y.1    Berk, D.A.2    Leunig, M.3    Baxter, L.T.4    Jain, R.K.5
  • 58
    • 27944436640 scopus 로고    scopus 로고
    • Spread of human cancer cells occurs with probabilities indicative of a nongenetic mechanism
    • Michaelson J.S., Cheongsiatmoy J.A., Dewey F., et al. Spread of human cancer cells occurs with probabilities indicative of a nongenetic mechanism. Br J Cancer 2005, 93:1244-1249.
    • (2005) Br J Cancer , vol.93 , pp. 1244-1249
    • Michaelson, J.S.1    Cheongsiatmoy, J.A.2    Dewey, F.3
  • 59
    • 68149138796 scopus 로고    scopus 로고
    • Biophysical model of tumor growth
    • Tracqui P. Biophysical model of tumor growth. Rep Prog Phys 2009, 72:1-30.
    • (2009) Rep Prog Phys , vol.72 , pp. 1-30
    • Tracqui, P.1
  • 60
    • 0029898270 scopus 로고    scopus 로고
    • How important is tumour shape? Quantification of the epithelial connective tissue interface in oral lesions using local connected fractal dimension analysis
    • Landini G., Rippin J.W. How important is tumour shape? Quantification of the epithelial connective tissue interface in oral lesions using local connected fractal dimension analysis. J Pathol 1996, 179:210-217.
    • (1996) J Pathol , vol.179 , pp. 210-217
    • Landini, G.1    Rippin, J.W.2
  • 61
    • 0042381698 scopus 로고    scopus 로고
    • Quantification of the global and local complexity of the epithelial-connective tissue interface of normal, dysplastic, and neoplastic oral mucose using digital imaging
    • Eid R.A., Landini G. Quantification of the global and local complexity of the epithelial-connective tissue interface of normal, dysplastic, and neoplastic oral mucose using digital imaging. Pathol Res Pract 2003, 199:475-482.
    • (2003) Pathol Res Pract , vol.199 , pp. 475-482
    • Eid, R.A.1    Landini, G.2
  • 62
    • 79960733138 scopus 로고    scopus 로고
    • Fractal structure of space and time is necessary for the emergence of self-organization, connectivity and collectivity in cellular system
    • Birkhauser Verlag, Basel, G.A. Losa, D. Merlini, T.F. Nonnenmacher, E.R. Weibel (Eds.)
    • Waliszewski P., Konarski J. Fractal structure of space and time is necessary for the emergence of self-organization, connectivity and collectivity in cellular system. Fractals in biology and medicine 2002, 15-24. Birkhauser Verlag, Basel. G.A. Losa, D. Merlini, T.F. Nonnenmacher, E.R. Weibel (Eds.).
    • (2002) Fractals in biology and medicine , pp. 15-24
    • Waliszewski, P.1    Konarski, J.2
  • 63
    • 0018140371 scopus 로고
    • Role of cell shape in growth control
    • Folkman J., Moscona A. Role of cell shape in growth control. Nature 1978, 273:345-349.
    • (1978) Nature , vol.273 , pp. 345-349
    • Folkman, J.1    Moscona, A.2
  • 64
    • 0032952039 scopus 로고    scopus 로고
    • How cells (might) sense microgravity
    • Ingber D.E. How cells (might) sense microgravity. FASEB J 1999, 13:S3-S15.
    • (1999) FASEB J , vol.13
    • Ingber, D.E.1
  • 65
    • 48349090284 scopus 로고    scopus 로고
    • Theories of carcinogenesis: an emerging perspective
    • Sonnenschein C., Soto A.M. Theories of carcinogenesis: an emerging perspective. Semin Cancer Biol 2008, 18:372-377.
    • (2008) Semin Cancer Biol , vol.18 , pp. 372-377
    • Sonnenschein, C.1    Soto, A.M.2
  • 66
    • 23844500338 scopus 로고    scopus 로고
    • Mechanical control of tissue growth: function follows form
    • Ingber D.E. Mechanical control of tissue growth: function follows form. Proc Natl Acad Sci U S A 2005, 102(33):11571-11572.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.33 , pp. 11571-11572
    • Ingber, D.E.1
  • 67
    • 0016801562 scopus 로고
    • Stochastic models for the Earth's relief, the shape and the fractal dimension of the coastlines, and the number-area rule for islands
    • Mandelbrot B.B. Stochastic models for the Earth's relief, the shape and the fractal dimension of the coastlines, and the number-area rule for islands. Proc Natl Acad Sci U S A 1975, 72:3825-3828.
    • (1975) Proc Natl Acad Sci U S A , vol.72 , pp. 3825-3828
    • Mandelbrot, B.B.1
  • 68
    • 0030298487 scopus 로고    scopus 로고
    • Fractal methods and results in cellular morphology - dimensions, lacunarity and multifractals
    • Smith T.G., Lange G.D., Marks W.B. Fractal methods and results in cellular morphology - dimensions, lacunarity and multifractals. J Neurosci Methods 1996, 69:123-136.
    • (1996) J Neurosci Methods , vol.69 , pp. 123-136
    • Smith, T.G.1    Lange, G.D.2    Marks, W.B.3
  • 70
    • 0004270978 scopus 로고
    • Springer Verlag, Heidelberg, Germany
    • Scheck F. Mechanics 1990, Springer Verlag, Heidelberg, Germany.
    • (1990) Mechanics
    • Scheck, F.1
  • 71
    • 0031825116 scopus 로고    scopus 로고
    • The thermodynamics and evolution of complexity in biological systems
    • Toussaint O., Schneider E.D. The thermodynamics and evolution of complexity in biological systems. Comp Biochem Physiol 1998, 120:3-9.
    • (1998) Comp Biochem Physiol , vol.120 , pp. 3-9
    • Toussaint, O.1    Schneider, E.D.2
  • 72
    • 27544510187 scopus 로고    scopus 로고
    • Stromal regulation of neoplastic development: age-dependent normalization of neoplastic mammary cells by mammary stroma
    • Maffini M.V., Calabro J.M., Soto A.M., Sonnenschein C. Stromal regulation of neoplastic development: age-dependent normalization of neoplastic mammary cells by mammary stroma. Am J Pathol 2005, 167(5):1405-1410.
    • (2005) Am J Pathol , vol.167 , Issue.5 , pp. 1405-1410
    • Maffini, M.V.1    Calabro, J.M.2    Soto, A.M.3    Sonnenschein, C.4
  • 73
    • 0344474148 scopus 로고
    • Nuclear transfer in Xenopus and Rana compared
    • Munksgaard, Copenhagen, R. Harris, P. Allin, D. Viza (Eds.)
    • McKinnell R.G. Nuclear transfer in Xenopus and Rana compared. Cell differentiation 1972, 61-64. Munksgaard, Copenhagen. R. Harris, P. Allin, D. Viza (Eds.).
    • (1972) Cell differentiation , pp. 61-64
    • McKinnell, R.G.1
  • 74
    • 0020842771 scopus 로고
    • The cancer cell and its control by the embryo
    • Pierce G.B. The cancer cell and its control by the embryo. Am J Pathol 1983, 113:116-124.
    • (1983) Am J Pathol , vol.113 , pp. 116-124
    • Pierce, G.B.1
  • 77
    • 0017549761 scopus 로고
    • An analysis technique for biological shape
    • Bowie J.E., Young I.T. An analysis technique for biological shape. Acta Cytol 1977, 21:739-746.
    • (1977) Acta Cytol , vol.21 , pp. 739-746
    • Bowie, J.E.1    Young, I.T.2
  • 78
    • 0000320233 scopus 로고    scopus 로고
    • The application and assessment of multiscale bending energy for morphometric characterization of neural cells
    • Cesar R.M., Costa L., da F. The application and assessment of multiscale bending energy for morphometric characterization of neural cells. Rev Sci Instrum 1997, 68:2177-2186.
    • (1997) Rev Sci Instrum , vol.68 , pp. 2177-2186
    • Cesar, R.M.1    Costa, L.2    da, F.3
  • 80
    • 0001111374 scopus 로고
    • Liquid properties of embryonic tissues: measurement of interfacial tensions
    • Foty R., Forgacs G., Pfleger C., Steimberg M. Liquid properties of embryonic tissues: measurement of interfacial tensions. Phys Rev Lett 1994, 72:2298-2301.
    • (1994) Phys Rev Lett , vol.72 , pp. 2298-2301
    • Foty, R.1    Forgacs, G.2    Pfleger, C.3    Steimberg, M.4
  • 81
    • 0030006921 scopus 로고    scopus 로고
    • Surface tensions of embryonic tissues predict their mutual envelopment behaviour
    • Foty R., Pfleger C., Forcas G., Steimberg M. Surface tensions of embryonic tissues predict their mutual envelopment behaviour. Development (Camb.) 1996, 122:1611-1620.
    • (1996) Development (Camb.) , vol.122 , pp. 1611-1620
    • Foty, R.1    Pfleger, C.2    Forcas, G.3    Steimberg, M.4
  • 82
    • 57649228961 scopus 로고    scopus 로고
    • Shape characterization of extracted and simulated tumor samples using topological and geometric measures. Engineering in medicine and biology society
    • SuA04.5:
    • Rohrschneider M., Scheuermann G., Hoehme S., Drasdo D. Shape characterization of extracted and simulated tumor samples using topological and geometric measures. Engineering in medicine and biology society. Proceedings of the 29th Annual International Conference of the IEEE EMBS 2007, SuA04.5: pp. 6271-6277.
    • (2007) Proceedings of the 29th Annual International Conference of the IEEE EMBS , pp. 6271-6277
    • Rohrschneider, M.1    Scheuermann, G.2    Hoehme, S.3    Drasdo, D.4
  • 83
    • 14944382346 scopus 로고    scopus 로고
    • Ignored hallmarks of carcinogenesis: stem cells and cell-cell communication
    • Trosko J.E., Chang C.-C., Upham B.L., Tai M.-H. Ignored hallmarks of carcinogenesis: stem cells and cell-cell communication. Ann N Y Acad Sci 2004, 1028:192-201.
    • (2004) Ann N Y Acad Sci , vol.1028 , pp. 192-201
    • Trosko, J.E.1    Chang, C.-C.2    Upham, B.L.3    Tai, M.-H.4
  • 85
    • 42749100495 scopus 로고    scopus 로고
    • Morphology transitions induced by chemotherapy in carcinomas in situ
    • Ferriera S.C., Martins M.L., Villa M.J. Morphology transitions induced by chemotherapy in carcinomas in situ. Phys Rev E 2003, 67:1-9.
    • (2003) Phys Rev E , vol.67 , pp. 1-9
    • Ferriera, S.C.1    Martins, M.L.2    Villa, M.J.3
  • 86
    • 67650267476 scopus 로고    scopus 로고
    • A new look at TCF and beta-catenin through the lens of a divergent C. elegans Wnt pathway
    • Phillips B.T., Kimble J. A new look at TCF and beta-catenin through the lens of a divergent C. elegans Wnt pathway. Dev Cell 2009, 17(1):27-34.
    • (2009) Dev Cell , vol.17 , Issue.1 , pp. 27-34
    • Phillips, B.T.1    Kimble, J.2
  • 87
    • 37649003774 scopus 로고    scopus 로고
    • Diagnosis of lung nodule using Moran's index and Geary's coefficient in computerized tomography images
    • da Silva E.C., Silva A.C., de Paiva A.C., Nunes R.A. Diagnosis of lung nodule using Moran's index and Geary's coefficient in computerized tomography images. Pattern Anal Appl 2008, 11:89-99.
    • (2008) Pattern Anal Appl , vol.11 , pp. 89-99
    • da Silva, E.C.1    Silva, A.C.2    de Paiva, A.C.3    Nunes, R.A.4
  • 88
    • 33750989571 scopus 로고
    • Biologie et thermodynamique des phenomenes irreversibles
    • Prigogine I., Wiame J.M. Biologie et thermodynamique des phenomenes irreversibles. Experientia 1946, 2:451-453.
    • (1946) Experientia , vol.2 , pp. 451-453
    • Prigogine, I.1    Wiame, J.M.2
  • 89
    • 0031470227 scopus 로고    scopus 로고
    • Phenomenological theory of ontogenesis
    • Zotin A.A., Zotin A.I. Phenomenological theory of ontogenesis. Int J Dev Biol 1997, 41:917-921.
    • (1997) Int J Dev Biol , vol.41 , pp. 917-921
    • Zotin, A.A.1    Zotin, A.I.2
  • 90
    • 17644410052 scopus 로고    scopus 로고
    • Emergentism as a default: cancer as a problem of tissue organization
    • Soto A.M., Sonnenschein C. Emergentism as a default: cancer as a problem of tissue organization. J Biosci 2005, 30(1):103-118.
    • (2005) J Biosci , vol.30 , Issue.1 , pp. 103-118
    • Soto, A.M.1    Sonnenschein, C.2
  • 91
    • 0034715919 scopus 로고    scopus 로고
    • Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks
    • Huang S., Ingber D.E. Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks. Exp Cell Res 2000, 261:91-103.
    • (2000) Exp Cell Res , vol.261 , pp. 91-103
    • Huang, S.1    Ingber, D.E.2
  • 92
    • 0032435266 scopus 로고    scopus 로고
    • Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus
    • Lelièvre S.A., Weaver V.M., Nickerson J.A., Larabell C.A., Bhaumik A., Petersen O.W., et al. Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proc Natl Acad Sci U S A 1998, 95:14711-14716.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14711-14716
    • Lelièvre, S.A.1    Weaver, V.M.2    Nickerson, J.A.3    Larabell, C.A.4    Bhaumik, A.5    Petersen, O.W.6
  • 93
    • 0037133313 scopus 로고    scopus 로고
    • Engineering gene expression and protein synthesis by modulation of nuclear shape
    • Thomas C.H., Collier J.H., Sfeir C.S., Healy K.E. Engineering gene expression and protein synthesis by modulation of nuclear shape. Proc Natl Acad Sci U S A 2002, 99:1972-1977.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1972-1977
    • Thomas, C.H.1    Collier, J.H.2    Sfeir, C.S.3    Healy, K.E.4
  • 95
    • 70349330663 scopus 로고    scopus 로고
    • Cancer attractors: a systems view of tumours from a gene network dynamics and developmental perspective
    • Huang S., Ernberg I., Kauffman S. Cancer attractors: a systems view of tumours from a gene network dynamics and developmental perspective. Semin Cell Dev Biol 2009, 20(7):869-876.
    • (2009) Semin Cell Dev Biol , vol.20 , Issue.7 , pp. 869-876
    • Huang, S.1    Ernberg, I.2    Kauffman, S.3
  • 96
    • 0030048999 scopus 로고    scopus 로고
    • Resynthesizing evolutionary and developmental biology
    • Gilbert S.F., Opitz J.M., Raff R.A. Resynthesizing evolutionary and developmental biology. Dev Biol 1996, 173:357-372.
    • (1996) Dev Biol , vol.173 , pp. 357-372
    • Gilbert, S.F.1    Opitz, J.M.2    Raff, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.