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Volumn 6, Issue 2, 2001, Pages 213-221

It takes a tissue to make a tumor: Epigenetics, cancer and the microenvironment

Author keywords

Carcinogenesis; Epigenetics; Ionizing radiation; Mammary; Stroma; Tissue

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1;

EID: 0035320245     PISSN: 10833021     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011317009329     Document Type: Article
Times cited : (107)

References (85)
  • 1
    • 0023613106 scopus 로고
    • The influence of extracellular matrix on gene expression: Is structure the message?
    • M. J. Bissell and M. H. Barcellos-Hoff (1987). The influence of extracellular matrix on gene expression: Is structure the message? J. Cell Sci. 8:327-343.
    • (1987) J. Cell Sci. , vol.8 , pp. 327-343
    • Bissell, M.J.1    Barcellos-Hoff, M.H.2
  • 3
    • 0014132760 scopus 로고
    • Mechanism of organogenetic tissue interaction
    • C. Grobstein (1967). Mechanism of organogenetic tissue interaction. Natl. Cancer Inst. Monogr. 26:279-299.
    • (1967) Natl. Cancer Inst. Monogr. , vol.26 , pp. 279-299
    • Grobstein, C.1
  • 4
    • 0014548693 scopus 로고
    • Organ specificity in mesenchymal induction demonstrated in the embryonic development of the mammary gland of the mouse
    • K. Kratochwil (1969). Organ specificity in mesenchymal induction demonstrated in the embryonic development of the mammary gland of the mouse. Dev. Biol. 20:46-71.
    • (1969) Dev. Biol. , vol.20 , pp. 46-71
    • Kratochwil, K.1
  • 5
    • 0034614379 scopus 로고    scopus 로고
    • Stem cells: A new lease on life
    • E. Fuchs and J. A. Segre (2000). Stem cells: A new lease on life. Cell 100:143-155.
    • (2000) Cell , vol.100 , pp. 143-155
    • Fuchs, E.1    Segre, J.A.2
  • 6
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • G. Evan and T. Littlewood (1998). A matter of life and cell death. Science 281:1317-1322.
    • (1998) Science , vol.281 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 7
    • 0021601376 scopus 로고
    • The multistep nature of cancer development
    • E. Farber (1984). The multistep nature of cancer development. Cancer Res. 44:4217-4223.
    • (1984) Cancer Res. , vol.44 , pp. 4217-4223
    • Farber, E.1
  • 8
    • 0024399684 scopus 로고
    • Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis
    • R. A. Weinberg (1989). Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. Cancer Res. 49:3713-3721.
    • (1989) Cancer Res. , vol.49 , pp. 3713-3721
    • Weinberg, R.A.1
  • 9
    • 0027363255 scopus 로고
    • Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia
    • S. H. Kim, K. A. Roth, A. R. Moser, and J. I. Gordon (1993). Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia. J. Cell Biol. 123:877-893.
    • (1993) J. Cell Biol. , vol.123 , pp. 877-893
    • Kim, S.H.1    Roth, K.A.2    Moser, A.R.3    Gordon, J.I.4
  • 10
    • 0023718895 scopus 로고
    • Stromal involvement in malignant growth
    • A. van den Hoof (1988). Stromal involvement in malignant growth. Adv. Cancer Res. 50:159-196.
    • (1988) Adv. Cancer Res. , vol.50 , pp. 159-196
    • van den Hoof, A.1
  • 11
    • 0032477806 scopus 로고    scopus 로고
    • Tumorigenic conversion of immortal human keratinocytes through stromal cell activation
    • M. Skobe and N. E. Fusenig (1998). Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc. Natl. Acad. Sci. U.S.A. 95:1050-1055.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 1050-1055
    • Skobe, M.1    Fusenig, N.E.2
  • 12
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • [news; comment]. 761
    • K. W. Kinzler and B. Vogelstein (1997).Cancer-susceptibility genes. Gatekeepers and caretakers [news; comment]. Nature 386:761, 763.
    • (1997) Nature , vol.386 , pp. 763
    • Kinzler, K.W.1    Vogelstein, B.2
  • 13
    • 0032524104 scopus 로고    scopus 로고
    • Landscaping the cancer terrain
    • [comment]
    • K. W. Kinzler and B. Vogelstein (1998). Landscaping the cancer terrain [comment]. Science 280:1036-1037.
    • (1998) Science , vol.280 , pp. 1036-1037
    • Kinzler, K.W.1    Vogelstein, B.2
  • 14
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D. Hanahan and R. A. Weinberg (2000). The hallmarks of cancer. Cell 100:57-50.
    • (2000) Cell , vol.100 , pp. 57-150
    • Hanahan, D.1    Weinberg, R.A.2
  • 15
    • 0018697307 scopus 로고
    • Dynamics of neoplastic development in carcinogen-exposed tracheal mucosa
    • M. Terzaghi and P. Nettesheim (1979). Dynamics of neoplastic development in carcinogen-exposed tracheal mucosa. Cancer Res. 39:3004-3010.
    • (1979) Cancer Res. , vol.39 , pp. 3004-3010
    • Terzaghi, M.1    Nettesheim, P.2
  • 16
    • 0022635919 scopus 로고
    • The rate of progression of radiation-transformed mammary epithelial cells is enhanced after low-dose-rate neutron irradiation
    • R. L. Ullrich (1986). The rate of progression of radiation-transformed mammary epithelial cells is enhanced after low-dose-rate neutron irradiation. Rad. Res. 105:68-75.
    • (1986) Rad. Res. , vol.105 , pp. 68-75
    • Ullrich, R.L.1
  • 17
    • 0028923298 scopus 로고
    • Evidence that carcinogenesis involves an imbalance between epigenetic high-frequency initiation and suppression of promotion
    • K. Kamiya, J. Yasukawa-Barnes, J. M. Mitchen, M. N. Gould, and K. H. Clifton (1995). Evidence that carcinogenesis involves an imbalance between epigenetic high-frequency initiation and suppression of promotion. Proc. Natl. Acad. Sci. U.S.A. 92:1332-1336.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 1332-1336
    • Kamiya, K.1    Yasukawa-Barnes, J.2    Mitchen, J.M.3    Gould, M.N.4    Clifton, K.H.5
  • 18
    • 0030031959 scopus 로고    scopus 로고
    • Elimination of transformed cells by normal cells: A novel concept for the control of carcinogenesis
    • G. Bauer (1996). Elimination of transformed cells by normal cells: A novel concept for the control of carcinogenesis. Histol. Histopathol. 11:237-255.
    • (1996) Histol. Histopathol. , vol.11 , pp. 237-255
    • Bauer, G.1
  • 19
    • 0033853415 scopus 로고    scopus 로고
    • How can tumor cells escape intercellular induction of apoptosis?
    • I. Engelmann and G. Bauer (2000). How can tumor cells escape intercellular induction of apoptosis? Anticancer Res. 20: 297-2306.
    • (2000) Anticancer Res. , vol.20 , pp. 2297-2306
    • Engelmann, I.1    Bauer, G.2
  • 20
    • 0033866723 scopus 로고    scopus 로고
    • Ex vivo tumor cell lines are resistant to intercellular induction of apoptosis and independent of exogenous survival factors
    • I. Engelmann, H. Eichholtz-Wirth, and G. Bauer (2000). Ex vivo tumor cell lines are resistant to intercellular induction of apoptosis and independent of exogenous survival factors. Anticancer Res. 20:2361-2370.
    • (2000) Anticancer Res. , vol.20 , pp. 2361-2370
    • Engelmann, I.1    Eichholtz-Wirth, H.2    Bauer, G.3
  • 21
    • 0023236342 scopus 로고
    • Inhibition of carcinogen-altered rat tracheal epithelial cell proliferation by normal epithelial cells in vivo
    • M. Terzaghi-Howe (1986). Inhibition of carcinogen-altered rat tracheal epithelial cell proliferation by normal epithelial cells in vivo. Carcinogenesis 8:145-150.
    • (1986) Carcinogenesis , vol.8 , pp. 145-150
    • Terzaghi-Howe, M.1
  • 22
    • 0032189662 scopus 로고    scopus 로고
    • Multiple changes in gene expression are associated with normal cell-induced modulation of the neoplastic phenotype
    • G.-W. Chang and M. Terzaghi-Howe (1998). Multiple changes in gene expression are associated with normal cell-induced modulation of the neoplastic phenotype. Cancer Res. 58:4445-4452.
    • (1998) Cancer Res. , vol.58 , pp. 4445-4452
    • Chang, G.-W.1    Terzaghi-Howe, M.2
  • 23
    • 0028978457 scopus 로고
    • Re-expression of the α2β 1 integrin abrogates malignant phenotype of breast carcinoma cells
    • M. M. Zutter, S. A. Santoro, W. D. Staatz, and Y. L. Tsung (1995). Re-expression of the α2β 1 integrin abrogates malignant phenotype of breast carcinoma cells. Proc. Natl. Acad. Sci. U.S.A. 92: 411-7415.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 7411-7415
    • Zutter, M.M.1    Santoro, S.A.2    Staatz, W.D.3    Tsung, Y.L.4
  • 24
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • V. M. Weaver, O. W. Petersen, F. Wang, C. A. Larabell, P. Briand, C. Damsky, and M. J. Bissell (1997). Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J. Cell Biol. 137:231-245.
    • (1997) J. Cell Biol. , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damsky, C.6    Bissell, M.J.7
  • 25
    • 0029888021 scopus 로고    scopus 로고
    • Interferon-α restores normal β1 integrin-mediated inhibition of hematopoietic progenitor proliferation by the marrow microenvironment in chronic myelogenous leukemia
    • R. Bhatia, J. B. McCarthy, and C. M. Verfaillie (1996). Interferon-α restores normal β1 integrin-mediated inhibition of hematopoietic progenitor proliferation by the marrow microenvironment in chronic myelogenous leukemia. Blood 87:3883-3891.
    • (1996) Blood , vol.87 , pp. 3883-3891
    • Bhatia, R.1    McCarthy, J.B.2    Verfaillie, C.M.3
  • 26
    • 0034063909 scopus 로고    scopus 로고
    • Radiation carcinogenesis
    • J. B. Little (2000). Radiation carcinogenesis. Carcinogenesis 21:397-404.
    • (2000) Carcinogenesis , vol.21 , pp. 397-404
    • Little, J.B.1
  • 27
    • 0031457070 scopus 로고    scopus 로고
    • Chromosomal instability and its relationship to other end points of genomic instability
    • C. L. Limoli, M. I. Kaplan, J. Corcoran, M. Meyers, D. A. Boothman, and W. F. Morgan (1997). Chromosomal instability and its relationship to other end points of genomic instability. Cancer Res. 57: 557-5563.
    • (1997) Cancer Res. , vol.57 , pp. 5557-5563
    • Limoli, C.L.1    Kaplan, M.I.2    Corcoran, J.3    Meyers, M.4    Boothman, D.A.5    Morgan, W.F.6
  • 28
    • 0031770716 scopus 로고    scopus 로고
    • Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of α particles
    • E. I. Azzam, S. M. de Toledo, T. Gooding, and J. B. Little (1998). Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of α particles. Rad. Res. 150:497-504.
    • (1998) Rad. Res. , vol.150 , pp. 497-504
    • Azzam, E.I.1    de Toledo, S.M.2    Gooding, T.3    Little, J.B.4
  • 29
    • 0030919931 scopus 로고    scopus 로고
    • Extracellular factor(s) following exposure to α particles can cause sister chromatid exchanges in normal human cells
    • B. E. Lehnert and E. H. Goodwin (1997). Extracellular factor(s) following exposure to α particles can cause sister chromatid exchanges in normal human cells. Cancer Res. 57:2164-2171.
    • (1997) Cancer Res. , vol.57 , pp. 2164-2171
    • Lehnert, B.E.1    Goodwin, E.H.2
  • 30
    • 0033515074 scopus 로고    scopus 로고
    • The cellular ecology of progressive neoplastic transformation: A clonal analysis
    • M. Chow and H. Rubin (1999). The cellular ecology of progressive neoplastic transformation: A clonal analysis. Proc. Natl. Acad. Sci. U.S.A. 96:2093-2098.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 2093-2098
    • Chow, M.1    Rubin, H.2
  • 31
    • 0025486010 scopus 로고
    • Modulation of intercellular communication during radiation and chemical carcinogenesis
    • J. E. Trosko, C. C. Chang, and B. V. Madhukar (1990). Modulation of intercellular communication during radiation and chemical carcinogenesis. 123:241-251.
    • (1990) , vol.123 , pp. 241-251
    • Trosko, J.E.1    Chang, C.C.2    Madhukar, B.V.3
  • 32
    • 0033011006 scopus 로고    scopus 로고
    • Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog
    • I. Tomlinson and W. Bodmer (1999). Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog. Nature Med. 5:11-12.
    • (1999) Nature Med. , vol.5 , pp. 11-12
    • Tomlinson, I.1    Bodmer, W.2
  • 34
    • 0015852146 scopus 로고
    • Breast cancer: Induction of differentiation by embryonic tissue
    • J. J. Decosse, C. L. Gossens, J. F. Kuzma, and D. Unsworth (1973). Breast cancer: Induction of differentiation by embryonic tissue. Science 181:1057-1058.
    • (1973) Science , vol.181 , pp. 1057-1058
    • Decosse, J.J.1    Gossens, C.L.2    Kuzma, J.F.3    Unsworth, D.4
  • 35
    • 0017756381 scopus 로고
    • Intrauterine transplantation of rat basal cell carcinoma as a model for reconversion of malignant to benign growth
    • M. Cooper and H. Pinkus (1977). Intrauterine transplantation of rat basal cell carcinoma as a model for reconversion of malignant to benign growth. Cancer Res. 37:2544-2552.
    • (1977) Cancer Res. , vol.37 , pp. 2544-2552
    • Cooper, M.1    Pinkus, H.2
  • 36
    • 0002033611 scopus 로고
    • The possible role of abnormal fibroblasts in the phathogenesis of breast cancer
    • M. A. Rich, J. C. Hager, and D. M. Lopez, (eds.), Kluwer Academic Publishers, Boston
    • S. L. Schor, A. M. Schor, A. Howell, and J. Haggie (1988). The possible role of abnormal fibroblasts in the phathogenesis of breast cancer. In M. A. Rich, J. C. Hager, and D. M. Lopez, (eds.), Breast Cancer: Scientific and Chemical Progress, Kluwer Academic Publishers, Boston, pp. 142-157.
    • (1988) Breast Cancer: Scientific and Chemical Progress , pp. 142-157
    • Schor, S.L.1    Schor, A.M.2    Howell, A.3    Haggie, J.4
  • 37
    • 0023125444 scopus 로고
    • Hypothesis: Persistent expression of fetal phenotypic characteristics by fibroblasts is associated with an increased susceptibility to neoplastic disease
    • S. L. Schor, A. M. Schor, A. Howell, and D. Crowther (1987). Hypothesis: Persistent expression of fetal phenotypic characteristics by fibroblasts is associated with an increased susceptibility to neoplastic disease. Expl. Cell Biol. 55:11-17.
    • (1987) Expl. Cell Biol. , vol.55 , pp. 11-17
    • Schor, S.L.1    Schor, A.M.2    Howell, A.3    Crowther, D.4
  • 38
    • 0021893246 scopus 로고
    • Skin fibroblasts obtained from cancer patients display foetal-like migratory behavior on collagen gels
    • S. L. Schor, A. M. Schor, P. Durning, and G. Rushton (1985). Skin fibroblasts obtained from cancer patients display foetal-like migratory behavior on collagen gels. J. Cell Sci. 73:235-244.
    • (1985) J. Cell Sci. , vol.73 , pp. 235-244
    • Schor, S.L.1    Schor, A.M.2    Durning, P.3    Rushton, G.4
  • 39
    • 0028003705 scopus 로고
    • Phenotypic heteogeneity in breast fibroblasts: Functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma
    • A. M. Schor, G. Rushton, J. E. Ferguson, A. Howell, J. Redford, and S. L. Schor (1994). Phenotypic heteogeneity in breast fibroblasts: Functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma. Int. J. Cancer 59:25-32.
    • (1994) Int. J. Cancer , vol.59 , pp. 25-32
    • Schor, A.M.1    Rushton, G.2    Ferguson, J.E.3    Howell, A.4    Redford, J.5    Schor, S.L.6
  • 40
    • 0023188965 scopus 로고
    • Fibroblasts from relatives of hereditary breast cancer patients display fetal-like behavior in vitro
    • J. A. Haggie, S. L. Schor, A. Howell, J. M. Birch, and R. A. S. Sellwood (1987). Fibroblasts from relatives of hereditary breast cancer patients display fetal-like behavior in vitro. Lancet 1: 455-1457.
    • (1987) Lancet , vol.1 , pp. 1455-1457
    • Haggie, J.A.1    Schor, S.L.2    Howell, A.3    Birch, J.M.4    Sellwood, R.A.S.5
  • 41
    • 0018193772 scopus 로고
    • Enhancement of the tumorigenicity of preneoplastic mammary nodule lines by enzymatic dissociation
    • D. Medina, F. Shepherd, and T. Gropp (1978). Enhancement of the tumorigenicity of preneoplastic mammary nodule lines by enzymatic dissociation. JNCI 60:1121-1126.
    • (1978) JNCI , vol.60 , pp. 1121-1126
    • Medina, D.1    Shepherd, F.2    Gropp, T.3
  • 42
    • 0018578487 scopus 로고
    • Persistence of responsiveness of adult mouse mammary gland to induction by embryonic mesenchyme
    • T. Sakakura, Y. Sakagami, and Y. Nishizuka (1979). Persistence of responsiveness of adult mouse mammary gland to induction by embryonic mesenchyme. Dev. Biol. 72:201-210.
    • (1979) Dev. Biol. , vol.72 , pp. 201-210
    • Sakakura, T.1    Sakagami, Y.2    Nishizuka, Y.3
  • 43
    • 0019423314 scopus 로고
    • Accelerated mammary cancer development by fetal salivary mesenchyme isografted to adult mouse mammary epithelium
    • T. Sakakura, Y. Sakagami, and Y. Nishizuka (1981). Accelerated mammary cancer development by fetal salivary mesenchyme isografted to adult mouse mammary epithelium. J. Natl. Cancer Inst. 66:953-959.
    • (1981) J. Natl. Cancer Inst. , vol.66 , pp. 953-959
    • Sakakura, T.1    Sakagami, Y.2    Nishizuka, Y.3
  • 44
    • 0023270373 scopus 로고
    • Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia
    • M. Y. Gordon, C. R. Dowding, G. P. Riley, J. M. Goldman, and M. F. Greaves (1987). Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia. Nature 328:342-344.
    • (1987) Nature , vol.328 , pp. 342-344
    • Gordon, M.Y.1    Dowding, C.R.2    Riley, G.P.3    Goldman, J.M.4    Greaves, M.F.5
  • 45
    • 0028251039 scopus 로고
    • The tumor promoting effect of wounding: A possible role for TGFβ induced fibrotic stroma
    • M. H. Sieweke and M. J. Bissell (1994). The tumor promoting effect of wounding: A possible role for TGFβ induced fibrotic stroma. Crit. Rev. Oncogenesis 5:297-311.
    • (1994) Crit. Rev. Oncogenesis , vol.5 , pp. 297-311
    • Sieweke, M.H.1    Bissell, M.J.2
  • 46
    • 0014324643 scopus 로고
    • Role of host and tumor calcium in metastases
    • B. Fisher and E. R. Fisher (1968). Role of host and tumor calcium in metastases. Cancer Res. 28:1753-1758.
    • (1968) Cancer Res. , vol.28 , pp. 1753-1758
    • Fisher, B.1    Fisher, E.R.2
  • 47
    • 0022397711 scopus 로고
    • Wounding and its role in RSV-mediated tumor formation
    • D. S. Dolberg, R. Holingworth, M. Hertle, and M. J. Bissell (1985). Wounding and its role in RSV-mediated tumor formation. Science 230:676-678.
    • (1985) Science , vol.230 , pp. 676-678
    • Dolberg, D.S.1    Holingworth, R.2    Hertle, M.3    Bissell, M.J.4
  • 48
    • 0025082390 scopus 로고
    • Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice
    • A. C. Schuh, S. F. Keating, F. S. Moneclaro, P. K. Vogt, and M. L. Breitman (1990). Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice. Nature 346:756-760.
    • (1990) Nature , vol.346 , pp. 756-760
    • Schuh, A.C.1    Keating, S.F.2    Moneclaro, F.S.3    Vogt, P.K.4    Breitman, M.L.5
  • 49
    • 0031426654 scopus 로고    scopus 로고
    • Matrix metalloproteinase stomelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and premalignant phentoype in mammary epithelial cells
    • A. Lochter, S. Galosy, J. Muschler, N. Freedman, Z. Werb, and M. J. Bissell (1997). Matrix metalloproteinase stomelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and premalignant phentoype in mammary epithelial cells. J. Cell Biol. 139:1861-1872.
    • (1997) J. Cell Biol. , vol.139 , pp. 1861-1872
    • Lochter, A.1    Galosy, S.2    Muschler, J.3    Freedman, N.4    Werb, Z.5    Bissell, M.J.6
  • 50
    • 0031877357 scopus 로고    scopus 로고
    • Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development
    • N. Thomasset, A. Lochter, C. J. Sympson, L. R. Lund, D. R. Williams, O. Behrendtsen, Z. Werb, and M. J. Bissell (1998). Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development. J. Amer. Sci. 153:457-467.
    • (1998) J. Amer. Sci. , vol.153 , pp. 457-467
    • Thomasset, N.1    Lochter, A.2    Sympson, C.J.3    Lund, L.R.4    Williams, D.R.5    Behrendtsen, O.6    Werb, Z.7    Bissell, M.J.8
  • 51
    • 0031956913 scopus 로고    scopus 로고
    • Hierarchcal and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents
    • J. E. Trosko (1998). Hierarchcal and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents. Environ. Health Perspect. 106:331-339.
    • (1998) Environ. Health Perspect. , vol.106 , pp. 331-339
    • Trosko, J.E.1
  • 52
    • 0027293946 scopus 로고
    • Radiation-induced transforming growth factor β and subsequent extracellular matrix reorganization in murine mammary gland
    • M. H. Barcellos-Hoff (1993). Radiation-induced transforming growth factor β and subsequent extracellular matrix reorganization in murine mammary gland. Cancer Res. 53:3880-3886.
    • (1993) Cancer Res. , vol.53 , pp. 3880-3886
    • Barcellos-Hoff, M.H.1
  • 54
    • 0030770411 scopus 로고    scopus 로고
    • Latent transforming growth factor-β activation in situ: Quantitative and functional evidence following low dose irradiation
    • E. J. Ehrhart, A. Carroll, P. Segarini, M. L.-S. Tsang, and M. H. Barcellos-Hoff (1997). Latent transforming growth factor-β activation in situ: Quantitative and functional evidence following low dose irradiation. FASEB J 11:991-1002.
    • (1997) FASEB J. , vol.11 , pp. 991-1002
    • Ehrhart, E.J.1    Carroll, A.2    Segarini, P.3    Tsang, M.L.-S.4    Barcellos-Hoff, M.H.5
  • 55
    • 0031773119 scopus 로고    scopus 로고
    • How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues
    • M. H. Barcellos-Hoff (1998). How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues. Rad. Res. 150:S109-S120.
    • (1998) Rad. Res. , vol.150
    • Barcellos-Hoff, M.H.1
  • 56
    • 0032034449 scopus 로고    scopus 로고
    • The potential influence of radiation-induced microenvironments in neoplastic progression
    • M. H. Barcellos-Hoff (1998). The potential influence of radiation-induced microenvironments in neoplastic progression. J. Mam. Gland Biol. Neoplasia 3:165-175.
    • (1998) J. Mam. Gland Biol. Neoplasia , vol.3 , pp. 165-175
    • Barcellos-Hoff, M.H.1
  • 57
    • 0034161922 scopus 로고    scopus 로고
    • Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
    • M. H. Barcellos-Hoff and S. A. Ravani (2000). Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. Cancer Res. 60:1254-1260.
    • (2000) Cancer Res. , vol.60 , pp. 1254-1260
    • Barcellos-Hoff, M.H.1    Ravani, S.A.2
  • 59
    • 0025605879 scopus 로고
    • Tumor radiocurability: Relationship to intrinsic tumor eterogeneity and to the tumor bed effect
    • J. T. Leith and S. Michelson (1990). Tumor radiocurability: Relationship to intrinsic tumor eterogeneity and to the tumor bed effect. Invasion Metastasis 10:329-351.
    • (1990) Invasion Metastasis , vol.10 , pp. 329-351
    • Leith, J.T.1    Michelson, S.2
  • 60
    • 0034234253 scopus 로고    scopus 로고
    • Reproductive state of rat mammary gland stroma modulates human breast cancer cell migration and invasion
    • L. T. Bemis and P. Schedin (2000). Reproductive state of rat mammary gland stroma modulates human breast cancer cell migration and invasion. Cancer Res. 60:3414-3418.
    • (2000) Cancer Res. , vol.60 , pp. 3414-3418
    • Bemis, L.T.1    Schedin, P.2
  • 61
    • 0017657533 scopus 로고
    • Epithelial-stromal interactions in normal and chemical carcinogen-treated adult bladder
    • G. M. Hodges, R. M. Hicks, and G. D. Spacey (1977). Epithelial-stromal interactions in normal and chemical carcinogen-treated adult bladder. Cancer Res. 37:3720-3730.
    • (1977) Cancer Res. , vol.37 , pp. 3720-3730
    • Hodges, G.M.1    Hicks, R.M.2    Spacey, G.D.3
  • 62
    • 0028287098 scopus 로고
    • N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations
    • R. S. Cha, W. G. Thilly, and H. Zarbl (1994). N-nitroso-N- ethylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations. PNAS 91:3749-3753.
    • (1994) PNAS , vol.91 , pp. 3749-3753
    • Cha, R.S.1    Thilly, W.G.2    Zarbl, H.3
  • 63
    • 0025739765 scopus 로고
    • Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells
    • A. Haimovitz-Friedman, I. Vlodavsky, A. Chaudhuri, L. Witte, and Z. Fuks (1991). Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells. Cancer Res. 51: 552-2558.
    • (1991) Cancer Res. , vol.51 , pp. 2552-2558
    • Haimovitz-Friedman, A.1    Vlodavsky, I.2    Chaudhuri, A.3    Witte, L.4    Fuks, Z.5
  • 64
    • 1842337424 scopus 로고    scopus 로고
    • 1 arrest by cell-substratum interactions
    • 1 arrest by cell-substratum interactions. Cancer Res. 57: 151-1156.
    • (1997) Cancer Res. , vol.57 , pp. 1151-1156
    • Gadbois, D.M.1    Lehnert, B.E.2
  • 65
    • 0023829813 scopus 로고
    • Altruistic cell suicide in relation to radiation hormesis
    • S. Kondo (1988). Altruistic cell suicide in relation to radiation hormesis. Int. J. Radiat. Biol. Phys. Chem. Med. 53:95-102.
    • (1988) Int. J. Radiat. Biol. Phys. Chem. Med. , vol.53 , pp. 95-102
    • Kondo, S.1
  • 66
    • 0025719982 scopus 로고
    • Cytokines in context
    • C. Nathan and M. Sporn (1991). Cytokines in context. J.Cell Biol. 113:981-986.
    • (1991) J. Cell Biol. , vol.113 , pp. 981-986
    • Nathan, C.1    Sporn, M.2
  • 68
    • 0034644472 scopus 로고    scopus 로고
    • TGF-β signaling in growth control, cancer, and heritable disorders
    • J. Massague, S. W. Blain, and R. S. Lo (2000). TGF-β signaling in growth control, cancer, and heritable disorders. Cell 103:295-309.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 69
    • 0028574054 scopus 로고
    • Skin wound healing: Transforming growth factor β antagonists decrease scarring and improve quality
    • M. W. J. Ferguson (1994). Skin wound healing: Transforming growth factor β antagonists decrease scarring and improve quality. J. Interferon Res. 14:303-304.
    • (1994) J. Interferon Res. , vol.14 , pp. 303-304
    • Ferguson, M.W.J.1
  • 71
    • 0032534450 scopus 로고    scopus 로고
    • Blockade of tumor cell transforming growth factor-βs enhances cell cycle progression and sensitizes human breast carcinoma cells to cytotoxic chemotherapy
    • T. Ohmori, J. L. Yang, J. O. Price, and C. L. Arteaga (1998). Blockade of tumor cell transforming growth factor-βs enhances cell cycle progression and sensitizes human breast carcinoma cells to cytotoxic chemotherapy. Exp. Cell Res. 245:350-359.
    • (1998) Exp. Cell Res. , vol.245 , pp. 350-359
    • Ohmori, T.1    Yang, J.L.2    Price, J.O.3    Arteaga, C.L.4
  • 72
    • 0030993935 scopus 로고    scopus 로고
    • Reversal of in vivo drug resistance by the transforming growth factor-β inhibitor decorin
    • B. A. Teicher, Y. Maehara, Y. Kakeji, G. Ara, S. R. Keyes, J. Wong, and R. Herbst (1997). Reversal of in vivo drug resistance by the transforming growth factor-β inhibitor decorin. Int. J. Cancer 71:49-58.
    • (1997) Int. J. Cancer , vol.71 , pp. 49-58
    • Teicher, B.A.1    Maehara, Y.2    Kakeji, Y.3    Ara, G.4    Keyes, S.R.5    Wong, J.6    Herbst, R.7
  • 73
    • 0344507146 scopus 로고    scopus 로고
    • Three distinct roles for TGF-β during intercellular induction of apoptosis: A review
    • T. Häufel, S. Dormann, J. Hanusch, A. Schwieger, and G. Bauer (1999). Three distinct roles for TGF-β during intercellular induction of apoptosis: A review. Anticancer Res. 19: 105-111.
    • (1999) Anticancer Res. , vol.19 , pp. 105-111
    • Häufel, T.1    Dormann, S.2    Hanusch, J.3    Schwieger, A.4    Bauer, G.5
  • 74
    • 0025354027 scopus 로고
    • Mediation of wound-related Rous sarcoma virus tumorigenesis and TGF-β
    • M. H. Sieweke, N. L. Thompson, M. B. Sporn, and M. J. Bissell (1990). Mediation of wound-related Rous sarcoma virus tumorigenesis and TGF-β. Science 248:1656-1660.
    • (1990) Science , vol.248 , pp. 1656-1660
    • Sieweke, M.H.1    Thompson, N.L.2    Sporn, M.B.3    Bissell, M.J.4
  • 75
    • 0024334332 scopus 로고
    • Stimulatory role of transforming growth factors in multistage skin carcinogenesis: Possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin
    • G. Furstenberger, M. Rogers, R. Schnapki, G. Bauer, P. Hofler, and F. Marks (1989). Stimulatory role of transforming growth factors in multistage skin carcinogenesis: Possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin. Int. J. Cancer 43:915-921.
    • (1989) Int. J. Cancer , vol.43 , pp. 915-921
    • Furstenberger, G.1    Rogers, M.2    Schnapki, R.3    Bauer, G.4    Hofler, P.5    Marks, F.6
  • 76
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis
    • T. M. Fynan and M. Reiss (1993). Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis. Crit. Rev. Oncogen. 4:493-540.
    • (1993) Crit. Rev. Oncogen. , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 78
    • 0030598681 scopus 로고    scopus 로고
    • TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
    • W. Cui, D. J. Fowlis, S. Bryson, E. Duffie, H. Ireland, A. Balmain, and R. J. Akhurst (1996). TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell 86:531-542.
    • (1996) Cell , vol.86 , pp. 531-542
    • Cui, W.1    Fowlis, D.J.2    Bryson, S.3    Duffie, E.4    Ireland, H.5    Balmain, A.6    Akhurst, R.J.7
  • 79
    • 0031817391 scopus 로고    scopus 로고
    • Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion
    • G. Portella, S. A. Cumming, J. Liddell, W. Cui, H. Ireland, R. J. Akhurst, and A. Balmain (1998). Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion. Cell Growth Differ. 9: 93-404.
    • (1998) Cell Growth Differ. , vol.9 , pp. 393-404
    • Portella, G.1    Cumming, S.A.2    Liddell, J.3    Cui, W.4    Ireland, H.5    Akhurst, R.J.6    Balmain, A.7
  • 80
    • 0032500010 scopus 로고    scopus 로고
    • Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development
    • C. Amendt, P. Schirmacher, H. Weber, and M. Blessing (1998). Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development. Oncogene 17:25-34.
    • (1998) Oncogene , vol.17 , pp. 25-34
    • Amendt, C.1    Schirmacher, P.2    Weber, H.3    Blessing, M.4
  • 81
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • E. D. Hay (1995). An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) 1:8-20.
    • (1995) Acta Anat. (Basel) , vol.1 , pp. 8-20
    • Hay, E.D.1
  • 85
    • 0033593025 scopus 로고    scopus 로고
    • Defects in transforming growth factor-β signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes
    • A. Glick, N. Popescu, V. Alexander, H. Ueno, E. Bottinger, and S. H. Yuspa (1999). Defects in transforming growth factor-β signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes. Proc. Nat. Acad. of Sci. U.S.A. 96:14949-14954.
    • (1999) Proc. Nat. Acad. of Sci. U.S.A. , vol.96 , pp. 14949-14954
    • Glick, A.1    Popescu, N.2    Alexander, V.3    Ueno, H.4    Bottinger, E.5    Yuspa, S.H.6


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