Metabolism and cell shape in cancer: A fractal analysis

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 7, 2011, Pages 1052-1058

  D'Anselmi, Fabrizio ^a,c   Valerio, Mariacristina ^b,c   Cucina, Alessandra ^c   Galli, Luca ^d   Proietti, Sara ^c   Dinicola, Simona ^c   Pasqualato, Alessia ^e   Manetti, Cesare ^c   Ricci, Giulia ^f   Giuliani, Alessandro ^g   Bizzarri, Mariano ^c  

^a ITALIAN SPACE AGENCY   (Italy)

^b REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Advanced Computer Systems SpA   (Italy)

^e UNIVERSITY OF CHIETI   (Italy)

^f SECOND UNIVERSITY OF NAPLES   (Italy)

^g ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Bending energy; Fractal morphology; Morphogenetic field; Phenotype reversion; Tumour metabolome

Indexed keywords

CITRIC ACID; FATTY ACID; FORMIC ACID; GLUCOSE; LACTIC ACID;

ARTICLE; BREAST CANCER; CANCER CELL; CELL MEMBRANE; CELL SHAPE; CELL STRAIN MCF 7; CELL STRUCTURE; FRACTAL ANALYSIS; GLYCOLYSIS; HUMAN; HUMAN CELL; METABOLOME; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE METABOLISM; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MEMBRANE; CELL SHAPE; ENERGY METABOLISM; FEMALE; FRACTALS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; METABOLOME; PRINCIPAL COMPONENT ANALYSIS; TIME FACTORS;

EID: 79958109352     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.05.002     Document Type: Article

References (34)

1. J.W. Baish, and R.K. Jain Fractals and cancer Cancer Res 60 2000 3683 3688 (Pubitemid 32204551)
2. J. Boonstra Growth factor-induced signal transduction in adherent mammalian cells is sensitive to gravity FASEB 13 1999 S35 S42
3. J.E. Bowie, and I.T. Young An analysis technique for biological shape Acta Cytol 21 1977 739 746
4. G. Carmeliet, and R. Bouillon The effect of microgravity on morphology and gene expression of osteoblasts in vitro FASEB 13 1999 S129 S134
5. M. Cascante, L.G. Boros, B. Comin-Anduix, P. de Atauri, J.J. Centelles, and P.W. Lee Metabolic control analysis in drug discovery and disease Nat Biotechnol 20 2002 243 249 (Pubitemid 34205416)
6. M.R. Cesar Jr., and L. da Fontoura Costa The application and assessment of multiscale bending energy for morphometric characterization of neural cells Rev Sci Instrum 68 1997 2177 2186 (Pubitemid 127639163)
7. C.S. Chen, M. Mrksich, S. Huang, G.M. Withesides, and D.E. Ingber Geometric control of cell life and death Science 276 1997 1425 1428 (Pubitemid 27235413)
8. V. Cristini, H.B. Frieboes, R. Gatenby, S. Caserta, M. Ferrari, and J. Sinek Morphologic instability and cancer invasion Clin Cancer Res 11 19 2005 6772 6779 (Pubitemid 41428730)
9. S.S. Cross Fractals in pathology J Pathol 182 1997 1 8 (Pubitemid 27240443)
10. A. Cucina, P.M. Biava, F. D'Anselmi, P. Coluccia, F. Conti, and R. Di Clemente Zebrafish embryo proteins induce apoptosis in human colon cancer cells (Caco2) Apoptosis 11 9 2006 1617 1628 (Pubitemid 44253678)
11. R. De Berardinis, J.J. Lum, G. Hatzivassiliou, and C.B. Thompson The biology of cancer: metabolic reprogramming fuels cell growth and proliferation Cell Metab 7 2008 11 20
12. S.C. Ferreira, M.L. Martins, and M.J. Villa Morphology transitions induced by chemotherapy in carcinomas in situ Phys Rev E 67 2003 1 9
13. R. Foty, G. Forgacs, C. Pfleger, and M. Steimberg Liquid properties of embryonic tissues: measurement of interfacial tensions Phys Rev Lett 72 1994 2298 2301 (Pubitemid 24975149)
14. R. Foty, C. Pfleger, G. Forcas, and M. Steimberg Surface tensions of embryonic tissues predict their mutual envelopment behaviour Development 122 1996 1611 1620 (Pubitemid 26159647)
15. F. Guilak Compression-induced changes in the shape and volume of the chondrocyte nucleus J Biomech 28 1995 1529 1541 (Pubitemid 26004298)
16. M.J. Hendrix, E.A. Seftor, R.E. Seftor, J. Kasemeier-Kulesa, P.M. Kulesa, and L.M. Postovit Reprogramming metastatic tumour cells with embryonic microenvironments Nat Rev Cancer 7 4 2007 246 255 (Pubitemid 46480969)
17. D.E. Ingber How cells (might) sense microgravity FASEB 13 1999 S3 S15
18. D.E. Ingber Mechanical control of tissue growth: function follows form Proc Natl Acad Sci USA 102 33 2005 11571 11572 (Pubitemid 41170767)
19. P.A. Kenny, and M.J. Bissell Tumor reversion: correction of malignant behaviour by microenvironmental cues Int J Cancer 107 2003 688 695 (Pubitemid 37339720)
20. S.A. Lelivre, V.M. Weaver, J.A. Nickerson, C.A. Larabell, A. Bhaumik, and O.W. Petersen Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus Proc Natl Acad Sci USA 95 1998 14711 14716 (Pubitemid 29003695)
21. G.A. Losa, D. Merloini, T.F. Nonnenmacher, and E.R. Weibel Fractals in biology and medicine 1st ed. 2002 Birkhauser Verlag AG Basel
22. B.B. Mandelbrott The fractal geometry of the nature 1982 WH Freeman New York
23. W.L. McKeehan Glycolysis, glutaminolysis and cell proliferation Cell Biol Int Rep 18 1982 3275 3282
24. A.L. Meadows, B. Kong, M. Berdichevsky, S. Roy, R. Rosiva, and H.W. Blanch Metabolic and morphological differences between rapidly proliferative cancerous and normal breast epithelial cells Biotechnol Prog 24 2008 334 341 (Pubitemid 351520346)
25. I. Prigogine, and J.M. Wiame Biologie et Thermodynamique des phenomenes irreversibles Experientia 2 1946 451 453
26. M. Rohrschneider, G. Scheuermann, S. Hoehme, and D. Drasdo Shape characterization of extracted and simulated tumor samples using topological and geometric measures Proceedings of the 29th annual international conference of the IEEE EMBS 2007 Engineering in Medicine and Biology Society 6271 6277
27. A. Sebri, J. Malek, and R. Tourki Automated breast cancer diagnosis based on GVF-snake segmentation, wavelet features extraction and neural network classification J Comput Sci 3 8 2007 600 607
28. T.G. Smith, G.D. Lange, and W.B. Marks Fractal methods and results in cellular morphology - dimensions, lacunarity and multifractals J Neurosci Methods 69 1996 123 136 (Pubitemid 26377770)
29. C.H. Thomas, J.H. Collier, C.S. Sfeir, and K.E. Healy Engineering gene expression and protein synthesis by modulation of nuclear shape Proc Natl Acad Sci USA 99 2002 1972 1977 (Pubitemid 34168999)
30. A. Tomassini, A. Miccheli, R. Di Clemente, M. Valerio, P. Coluccia, and M. Bizzarri NMR-based metabolic profiling of human hepatoma cells in relation to cell growth Biochim Biophys Acta 1760 11 2006 1723 1731 (Pubitemid 44667274)
31. J.E. Trosko, C.C. Chang, B.L. Upham, and M.H. Tai Ignored hallmarks of carcinogenesis: stem cells and cell-cell communication Ann NY Acad Sci 1028 2004 192 201 (Pubitemid 40361822)
32. T. Wang, C. Marquardt, and J. Foker Aerobic glycolysis during lymphocite proliferation Nature 261 1976 702 705
33. C. Xu, and J.L. Prince Generalized gradient vector flow external forces for active contours Signal Process 71 2 1998 131 139 (Pubitemid 128428376)
34. A.A. Zotin, and A.I. Zotin Phenomenological theory of ontogenesis Int J Dev Biol 41 1997 917 921 (Pubitemid 28027189)