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Volumn 18, Issue 8, 2011, Pages 525-532

The liver-cytokine-brain circuit in interferon-based treatment of patients with chronic viral hepatitis

Author keywords

chronic viral hepatitis; cytokines; interferon; interleukins; psychological disorders

Indexed keywords

ANTIVIRUS AGENT; CATECHOLAMINE; CITALOPRAM; CYTOKINE; GLUCOCORTICOID; INTERFERON; INTERLEUKIN 1; INTERLEUKIN 6; LEUKOTRIENE; NITRIC OXIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

EID: 79960682780     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2010.01418.x     Document Type: Review
Times cited : (13)

References (74)
  • 2
    • 33750342122 scopus 로고    scopus 로고
    • Psychiatric symptoms induced by antiviral therapy in chronic hepatitis C: Comparison between interferon-2a and interferon-2b
    • DOI 10.2165/00044011-200626110-00005
    • Neri S, Pulvirenti D, Bertino G,. Psychiatric symptoms induced by antiviral therapy in chronic hepatitis C: comparison between interferon-alpha-2a and interferon-alpha-2b. Clin Drug Investig 2006; 26: 655-662. (Pubitemid 44627849)
    • (2006) Clinical Drug Investigation , vol.26 , Issue.11 , pp. 655-662
    • Neri, S.1    Pulvirenti, D.2    Bertino, G.3
  • 3
    • 33846491758 scopus 로고    scopus 로고
    • Interferon-induced depressive symptoms are related to changes in the cytokine network but not to cortisol
    • DOI 10.1016/j.jpsychores.2006.09.007, PII S0022399906004296
    • Wichers MC, Kenis G, Koek GH, Robayes G, Nicolson NA, Maes M,. Interferon-alpha-induced depressive symptoms are related to changes in the cytokine network but not to cortisol. J Psychosom Res 2007; 62: 207-214. (Pubitemid 46161588)
    • (2007) Journal of Psychosomatic Research , vol.62 , Issue.2 , pp. 207-214
    • Wichers, M.C.1    Kenis, G.2    Koek, G.H.3    Robaeys, G.4    Nicolson, N.A.5    Maes, M.6
  • 5
    • 27644531963 scopus 로고    scopus 로고
    • Depression and anxiety in patients with hepatitis C: Prevalence, detection rates and risk factors
    • DOI 10.1016/j.genhosppsych.2005.06.006, PII S0163834305001076
    • Golden J, O'Dwyer AM, Conroy RM,. Depression and anxiety in patients with hepatitis C: prevalence, detection rates and risk factors. Gen Hosp Psychiatry 2005; 27 (6): 431-438. (Pubitemid 41566070)
    • (2005) General Hospital Psychiatry , vol.27 , Issue.6 , pp. 431-438
    • Golden, J.1    O'Dwyer, A.M.2    Conroy, R.M.3
  • 6
    • 77954098309 scopus 로고    scopus 로고
    • Effectiveness and tolerability of pegylated interferon alfa-2b in combination with ribavirin for treatment of chronic hepatitis C: The PegIntrust study
    • VanVlierberghe H, Adler M, Bastens B, et al. Effectiveness and tolerability of pegylated interferon alfa-2b in combination with ribavirin for treatment of chronic hepatitis C: the PegIntrust study. Acta Gastroenterol Belg 2010; 73: 5-11.
    • (2010) Acta Gastroenterol Belg , vol.73 , pp. 5-11
    • Vanvlierberghe, H.1    Adler, M.2    Bastens, B.3
  • 7
    • 77955984417 scopus 로고    scopus 로고
    • Pros and cons of peginterferon versus nucleos(t)ide analogues for treatment of chronic hepatitis B
    • Sonneveld MJ, Janssen HL,. Pros and cons of peginterferon versus nucleos(t)ide analogues for treatment of chronic hepatitis B. Curr Hepat Rep 2010; 9: 91-98.
    • (2010) Curr Hepat Rep , vol.9 , pp. 91-98
    • Sonneveld, M.J.1    Janssen, H.L.2
  • 8
    • 0029758921 scopus 로고    scopus 로고
    • Therapy of chronic viral hepatitis
    • Fried MW,. Therapy of chronic viral hepatitis. Med Clin North Am 1996; 80: 957-972. Review. (Pubitemid 26300280)
    • (1996) Medical Clinics of North America , vol.80 , Issue.5 , pp. 957-972
    • Fried, M.W.1
  • 9
    • 68949190798 scopus 로고    scopus 로고
    • Psychiatric problems in patients infected with hepatitis C before and during antiviral treatment with interferon-alpha: A review
    • Quelhas R, Lopes A,. Psychiatric problems in patients infected with hepatitis C before and during antiviral treatment with interferon-alpha: a review. J Psychiatric Pract 2009; 15: 262-281.
    • (2009) J Psychiatric Pract , vol.15 , pp. 262-281
    • Quelhas, R.1    Lopes, A.2
  • 10
    • 0141870105 scopus 로고    scopus 로고
    • Bénéfice d'une prise en charge préventive psychiatrique chez les patients séropositifs a l'hépatite C (VHC): Étude prospective concernant 39 patients
    • Lang JP, Meyer N, Doffoel M,. Benefits of a preventive psychiatric accompaniment in patients hepatitis C virus seropositive (HCV): prospective study concerning 39 patients. Encephale 2003; 29 (4 Pt 1): 362-365. (Pubitemid 37209902)
    • (2003) Encephale , vol.29 , Issue.4 , pp. 362-365
    • Lang, J.-Ph.1    Meyer, N.2    Doffoel, M.3
  • 11
    • 42449105828 scopus 로고    scopus 로고
    • Role of the brain-gut axis in the pathophysiology of Crohn's disease
    • DOI 10.1159/000116774
    • Stasi C, Orlandelli E,. Role of the brain-gut axis in the phathophysiology of Crohn's disease. Dig Dis 2008; 26: 156-166. (Pubitemid 351572141)
    • (2008) Digestive Diseases , vol.26 , Issue.2 , pp. 156-166
    • Stasi, C.1    Orlandelli, E.2
  • 12
    • 0033676266 scopus 로고    scopus 로고
    • The neurobiology of stress and gastrointestinal disease
    • Mayer EA,. The neurobiology of stress and gastrointestinal disease. Gut 2000; 46 (6): 861.
    • (2000) Gut , vol.46 , Issue.6 , pp. 861
    • Mayer, E.A.1
  • 13
    • 36849037934 scopus 로고    scopus 로고
    • Neurohormonal-cytokine interactions: Implications for inflammation, common human diseases and well-being
    • DOI 10.1016/j.neuint.2007.06.037, PII S0197018607001775, Non-Synaptic Transmission
    • Elenkov I,. Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being. Neurochem Int 2008; 52: 40-51. (Pubitemid 350235704)
    • (2008) Neurochemistry International , vol.52 , Issue.1 , pp. 40-51
    • Elenkov, I.J.1
  • 14
    • 0033695806 scopus 로고    scopus 로고
    • Stress, chronic inflammation, and emotional and physical well-being: Concurrent effects and chronic sequelae
    • Chrousos MD,. Stress, chronic inflammation, and emotional and physical well-being: concurrent effects and chronic sequelae. J Allergy Clin Immunol 2000; 106: S275-S291.
    • (2000) J Allergy Clin Immunol , vol.106
    • Chrousos, M.D.1
  • 15
    • 67650996483 scopus 로고    scopus 로고
    • The effect of tumor necrosis factor antagonists on mood and mental health-associated quality of life: Novel hypothesis-driven treatments for bipolar depression?
    • Soczynska JK, Kennedy SH, Goldstein BI, Lachowski A, Woldeyohannes HO, McIntyre RS,. The effect of tumor necrosis factor antagonists on mood and mental health-associated quality of life: novel hypothesis-driven treatments for bipolar depression? Neurotoxicology 2009; 30: 497-521.
    • (2009) Neurotoxicology , vol.30 , pp. 497-521
    • Soczynska, J.K.1    Kennedy, S.H.2    Goldstein, B.I.3    Lachowski, A.4    Woldeyohannes, H.O.5    McIntyre, R.S.6
  • 16
    • 58049190133 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1): A central regulator of stress responses
    • Goshen I, Yirmiya R,. Interleukin-1 (IL-1): a central regulator of stress responses. Front Neuroendocrinol 2009; 30: 30-45.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 30-45
    • Goshen, I.1    Yirmiya, R.2
  • 17
    • 4444256765 scopus 로고    scopus 로고
    • Cytokines: Abnormalities in major depression and implications for pharmacological treatment
    • DOI 10.1002/hup.609
    • O'Brien SM, Scott LV, Dinan TG,. Cytokines: abnormalities in major depression and implications for pharmacological treatment. Hum Psychopharmacol 2004; 19: 397-403. (Pubitemid 39172804)
    • (2004) Human Psychopharmacology , vol.19 , Issue.6 , pp. 397-403
    • O'Brien, S.M.1    Scott, L.V.2    Dinan, T.G.3
  • 19
    • 16244405882 scopus 로고    scopus 로고
    • Prevalence and significance of neurocognitive dysfunction in hepatitis C in the absence of correlated risk factors
    • DOI 10.1002/hep.20635
    • McAndrews MP, Farcnik K, Calen P, et al. Prevalence and significance of neurocognitive disfunction in hepatitis C in the absence of correlated risk factors. Hepatology 2005; 41: 801-808. (Pubitemid 40462942)
    • (2005) Hepatology , vol.41 , Issue.4 , pp. 801-808
    • McAndrews, M.P.1    Farcnik, K.2    Carlen, P.3    Damyanovich, A.4    Mrkonjic, M.5    Jones, S.6    Heathcote, E.J.7
  • 20
    • 0037349968 scopus 로고    scopus 로고
    • Cerebral dysfunction in chronic hepatitis C infection
    • DOI 10.1046/j.1365-2893.2003.00416.x
    • Forton DM, Taylor-Robinson SD, Thomas HC,. Cerebral dysfunction in chronic hepatitis C infection. J Viral Hepat 2003; 10: 81-86. (Pubitemid 36359844)
    • (2003) Journal of Viral Hepatitis , vol.10 , Issue.2 , pp. 81-86
    • Forton, D.M.1    Taylor-Robinson, S.D.2    Thomas, H.C.3
  • 21
    • 33750300802 scopus 로고    scopus 로고
    • Hepatitis C virus infection and neurocognitive function
    • DOI 10.1212/01.wnl.0000240255.42608.99, PII 0000611420061024000037
    • Soogoor M, Lynn HS, Donfield SM, Gomperts E, Bell TS, Daar ES,. Hepatitis C virus infection and neurocognitive function. Neurology 2006; 67: 1482-1485. (Pubitemid 44632081)
    • (2006) Neurology , vol.67 , Issue.8 , pp. 1482-1485
    • Soogoor, M.1    Lynn, H.S.2    Donfield, S.M.3    Gomperts, E.4    Bell, T.S.5    Daar, E.S.6
  • 22
    • 0032773298 scopus 로고    scopus 로고
    • Fatigue does not correlate with the degree of hepatitis or the presence of autoimmune disorders in chronic hepatitis C infection
    • Goh J, Coughlan B, Quinn J, O'Keane JC, Crowe J,. Fatigue does not correlate with the degree of hepatitis or the presence of autoimmune disorders in chronic hepatitis C infection. Eur J Gastroenterol Hepatol 1999; 11: 833-838. (Pubitemid 29389513)
    • (1999) European Journal of Gastroenterology and Hepatology , vol.11 , Issue.8 , pp. 833-838
    • Goh, J.1    Coughlan, B.2    Quinn, J.3    O'Keane, J.C.4    Crowe, J.5
  • 25
    • 17144443590 scopus 로고    scopus 로고
    • Chronic hepatitis C virus infection causes a significant reduction in quality of life in the absence of cirrhosis
    • Foster GR, Goldin RD, Thomas HC,. Chronic hepatitis C virus infection causes a significant reduction in quality of life in the absence of cirrhosis. Hepatology 1998; 27: 209-212.
    • (1998) Hepatology , vol.27 , pp. 209-212
    • Foster, G.R.1    Goldin, R.D.2    Thomas, H.C.3
  • 27
    • 2342655833 scopus 로고    scopus 로고
    • Identification of Unique Hepatitis C Virus Quasispecies in the Central Nervous System and Comparative Analysis of Internal Translational Efficiency of Brain, Liver, and Serum Variants
    • DOI 10.1128/JVI.78.10.5170-5183.2004
    • Forton DM, Karayiannis P, Mahmud N, Taylor-Robinson SD, Thomas HC,. Identification of unique hepatitis C virus quasispecies in the central nervous system and comparative analysis of internal translational efficiency of brain, liver, and serum variants. J Virol 2004; 78 (10): 5170-5183. (Pubitemid 38581469)
    • (2004) Journal of Virology , vol.78 , Issue.10 , pp. 5170-5183
    • Forton, D.M.1    Karayiannis, P.2    Mahmud, N.3    Taylor-Robinson, S.D.4    Thomas, H.C.5
  • 29
    • 59749097933 scopus 로고    scopus 로고
    • Hepatitis C virus neuroinvasion: Identification of infected cells
    • Wilkinson J, Radkowski M, Laskus T,. Hepatitis C virus neuroinvasion: identification of infected cells. J Virol 2009; 83: 1312-1319.
    • (2009) J Virol , vol.83 , pp. 1312-1319
    • Wilkinson, J.1    Radkowski, M.2    Laskus, T.3
  • 32
    • 79960665362 scopus 로고    scopus 로고
    • Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy
    • Bokemeyer M, Ding XQ, Goldbecker A, et al. Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy. Gut 2010; doi:.
    • (2010) Gut
    • Bokemeyer, M.1    Ding, X.Q.2    Goldbecker, A.3
  • 33
    • 46749114788 scopus 로고    scopus 로고
    • (1)H MR spectroscopy of inflammation, infection and ischemia of the brain
    • Mader I, Rauer S, Gall P, Close U,. (1)H MR spectroscopy of inflammation, infection and ischemia of the brain. Eur J Radiol 2008; 67: 250-257.
    • (2008) Eur J Radiol , vol.67 , pp. 250-257
    • Mader, I.1    Rauer, S.2    Gall, P.3    Close, U.4
  • 34
    • 33847141978 scopus 로고    scopus 로고
    • N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology
    • DOI 10.1016/j.pneurobio.2006.12.003, PII S030100820600164X
    • Moffett JR, Ross B, Arun P, Madhavarao CN, Namboodiri AM,. N-acetylaspartate in the CNS: from neurodiagnostics to neurobiology. Prog Neurobiol 2007; 81 (2): 89-131. (Pubitemid 46282272)
    • (2007) Progress in Neurobiology , vol.81 , Issue.2 , pp. 89-131
    • Moffett, J.R.1    Ross, B.2    Arun, P.3    Madhavarao, C.N.4    Namboodiri, A.M.A.5
  • 35
    • 0030827379 scopus 로고    scopus 로고
    • N-acetylaspartylglutamate immunoreactivity in human brain and its alteration in neurodegenerative disease
    • Neale JH, Bzdega T, Wroblewska B,. N-acetylaspartylglutamate immunoreactivity in human brain and its alteration in neurodegenerative disease. Brain Res 1997; 772: 9-22.
    • (1997) Brain Res , vol.772 , pp. 9-22
    • Neale, J.H.1    Bzdega, T.2    Wroblewska, B.3
  • 36
    • 0037409849 scopus 로고    scopus 로고
    • N-acetylaspartate in the vertebrate brain: Metabolism and function
    • DOI 10.1023/A:1023250721185
    • Baslow MH,. N-acetylaspartate in the vertebral brain: metabolism and function. Neurochem Res 2003; 28: 941-953. (Pubitemid 36438413)
    • (2003) Neurochemical Research , vol.28 , Issue.6 , pp. 941-953
    • Baslow, M.H.1
  • 40
    • 0033596808 scopus 로고    scopus 로고
    • Elevated subcortical choline metabolites in cognitively and clinically asymptomatic HIV+ patients
    • Meyerhoff DJ, Bloomer C, Cardenas V, Norman D, Weiner MW, Fein G,. Elevated subcortical choline metabolites in cognitively and clinically asymptomatic HIV+ patients. Neurology 1999; 52: 995-1003. (Pubitemid 29161610)
    • (1999) Neurology , vol.52 , Issue.5 , pp. 995-1003
    • Meyerhoff, D.J.1    Bloomer, C.2    Cardenas, V.3    Norman, D.4    Weiner, M.W.5    Fein, G.6
  • 41
    • 0346908245 scopus 로고    scopus 로고
    • Applications of magnetic resonance spectroscopy to chronic liver disease
    • Taylor-Robinson SD,. Applications of magnetic resonance spectroscopy to chronic liver disease. Clin Med 2001; 1: 54-60.
    • (2001) Clin Med , vol.1 , pp. 54-60
    • Taylor-Robinson, S.D.1
  • 42
    • 36749033636 scopus 로고    scopus 로고
    • Correlations between magnetic resonance spectroscopy alterations and cerebral ammonia and glucose metabolism in cirrhotic patients with and without hepatic encephalopathy
    • DOI 10.1136/gut.2006.110569
    • Weissenborn K, Ahl B, Fischer-Wasels D, et al. Correlations between magnetic resonance spectroscopy alterations and cerebral ammonia and glucose metabolism in cirrhotic patients with and without hepatic encephalopathy. Gut 2007; 56: 1736-1742. (Pubitemid 350206301)
    • (2007) Gut , vol.56 , Issue.12 , pp. 1736-1742
    • Weissenborn, K.1    Ahl, B.2    Fischer-Wasels, D.3    Van Den Hoff, J.4    Hecker, H.5    Burchert, W.6    Kostler, H.7
  • 43
    • 77957189292 scopus 로고    scopus 로고
    • Activation of brain macrophages/microglia cells in hepatitis C infection
    • Wilkinson J, Radkowski M, Eschbacher JM, Laskus T,. Activation of brain macrophages/microglia cells in hepatitis C infection. Gut 2010; 59: 1394-1400.
    • (2010) Gut , vol.59 , pp. 1394-1400
    • Wilkinson, J.1    Radkowski, M.2    Eschbacher, J.M.3    Laskus, T.4
  • 44
    • 0033769653 scopus 로고    scopus 로고
    • The cytokine-HPA axis feed-back circuit
    • Besedovsky HO, del Rey A,. The cytokine-HPA axis feed-back circuit. Z Rheumatol 2000; 59 (Suppl. 2): II/26-II/30.
    • (2000) Z Rheumatol , vol.59 , Issue.SUPPL. 2
    • Besedovsky, H.O.1    Del Rey, A.2
  • 45
    • 0030484046 scopus 로고    scopus 로고
    • Chronic stimulation of the hypothalamus-pituitary-adrenal axis in rats by interleukin 1beta: Central and peripheral mechanisms
    • DOI 10.1006/cyto.1996.0122
    • van der Meer MJ, Sweep CG, Pesmanb GJ, Tilders FJ, Hermus AR,. Chronic stimulation of the Hypothalamus-pituitary-adrenal axis in rats by interleukin 1β: central and peripheral mechanisms. Cytokine 1996; 8: 910-919. (Pubitemid 27091192)
    • (1996) Cytokine , vol.8 , Issue.12 , pp. 910-919
    • Van Der Meer, M.J.M.1    Sweep, C.G.J.F.2    Pesman, G.J.3    Tilders, F.J.H.4    Hermus, A.R.M.M.5
  • 47
    • 0033773087 scopus 로고    scopus 로고
    • Reciprocal interactions between the neuroendocrine and immune systems during inflammation
    • Chikanza IC, Grossman AB,. Reciprocal interactions between the neuroendocrine and immune systems during inflammation. Rheum Dis Clin North Am 2000; 26: 693-711.
    • (2000) Rheum Dis Clin North Am , vol.26 , pp. 693-711
    • Chikanza, I.C.1    Grossman, A.B.2
  • 48
    • 23544438166 scopus 로고    scopus 로고
    • Cytokines mediate protective stimulation of glucocorticoid output during autoimmunity: Involvement of IL-1
    • del Rey A, Klusman I, Besedovsky HO,. Cytokines mediate protective stimulation of glucocorticoid output during autoimmunity: involvement of IL-1. Am J Physiol 1998; 275: 1146-1151.
    • (1998) Am J Physiol , vol.275 , pp. 1146-1151
    • Del Rey, A.1    Klusman, I.2    Besedovsky, H.O.3
  • 49
    • 0033283065 scopus 로고    scopus 로고
    • Effects of cytokines on glucocorticoid receptor expression and function. Glucocorticoid resistance and relevance to depression
    • Miller AH, Pariante CM, Pearce BD,. Effects of cytokines on glucocorticoid receptor expression and function. Glucocorticoid resistance and relevance to depression. Adv Exp Med Biol 1999; 461: 107-116.
    • (1999) Adv Exp Med Biol , vol.461 , pp. 107-116
    • Miller, A.H.1    Pariante, C.M.2    Pearce, B.D.3
  • 50
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: Inflammation and the pathogenesis of depression
    • DOI 10.1016/j.it.2005.11.006, PII S1471490605002887
    • Raison CL, Capuron L, Miller AH,. Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol 2006; 27: 24-31. (Pubitemid 43083561)
    • (2006) Trends in Immunology , vol.27 , Issue.1 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 51
    • 0027318761 scopus 로고
    • Suppression of hypothalamic-pituitary-adrenal axis responsiveness to stress in a rat model of acute cholestasis
    • Swain MG, Patchev V, Vergalla J, Chrousos G, Jones EA,. Suppression of hypothalamic-pituitary-adrenal axis responsiveness to stress in a rat model of acute cholestasis. J Clin Invest 1993; 91: 1903-1908. (Pubitemid 23141458)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.5 , pp. 1903-1908
    • Swain, M.G.1    Patchev, V.2    Vergalla, J.3    Chrousos, G.4    Jones, E.A.5
  • 53
    • 67650552723 scopus 로고    scopus 로고
    • Type I IFNs and their role in the development of autoimmune diseases
    • Burdick LM, Somani N, Somani AK,. Type I IFNs and their role in the development of autoimmune diseases. Expert Opin Drug Saf 2009; 8: 459-472.
    • (2009) Expert Opin Drug Saf , vol.8 , pp. 459-472
    • Burdick, L.M.1    Somani, N.2    Somani, A.K.3
  • 54
    • 0442272538 scopus 로고    scopus 로고
    • When not enough is too much: The role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders
    • DOI 10.1176/appi.ajp.160.9.1554
    • Raison CL, Miller AH,. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry 2003; 160: 1554-1565. (Pubitemid 41079539)
    • (2003) American Journal of Psychiatry , vol.160 , Issue.9 , pp. 1554-1565
    • Raison, C.L.1    Miller, A.H.2
  • 55
    • 0023077608 scopus 로고
    • Lymphocyte hormone receptors
    • Plaut M,. Lymphocyte hormone receptors. Annu Rev Immunol 1987; 5: 621-669.
    • (1987) Annu Rev Immunol , vol.5 , pp. 621-669
    • Plaut, M.1
  • 56
    • 0030449599 scopus 로고    scopus 로고
    • The relevance of opioids and opioid receptors on immunocompetence and immune homeostasis
    • Carr DJ, Rogers TJ, Weber RJ,. The relevance of opioids and opioid receptors on immunocompetence and immune homeostasis. Proc Soc Exp Biol Med 1996; 213: 248-257.
    • (1996) Proc Soc Exp Biol Med , vol.213 , pp. 248-257
    • Carr, D.J.1    Rogers, T.J.2    Weber, R.J.3
  • 61
    • 0024372380 scopus 로고
    • Stimulatory effect of corticotropin-releasing neurohormone on human lymphocyte proliferation and interleukin-2 receptor expression
    • DOI 10.1016/0165-5728(89)90058-1
    • Singh VK,. Stimulatory effect of corticotropin-releasing neurohormone on human lymphocyte proliferation and interleukin-2 receptor expression. J Neuroimmunol 1989; 23: 257-262. (Pubitemid 19190782)
    • (1989) Journal of Neuroimmunology , vol.23 , Issue.3 , pp. 257-262
    • Singh, V.K.1
  • 62
    • 0025705776 scopus 로고
    • Enhancing effect of corticotropin-releasing neurohormone on the production of interleukin-1 and interleukin-2
    • Singh VK, Leu SJ,. Enhancing effect of corticotropin-releasing neurohormone on the production of interleukin-1 and interleukin-2. Neurosci Lett 1990; 120: 151-154.
    • (1990) Neurosci Lett , vol.120 , pp. 151-154
    • Singh, V.K.1    Leu, S.J.2
  • 63
    • 0033992534 scopus 로고    scopus 로고
    • The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders
    • DOI 10.1016/S0306-4530(99)00035-9, PII S0306453099000359
    • Heim C, Ehlert U, Hellhammer DH,. The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders. Psychoneuroendocrinology 2000; 25: 1-35. (Pubitemid 29490865)
    • (2000) Psychoneuroendocrinology , vol.25 , Issue.1 , pp. 1-35
    • Heim, C.1    Ehlert, U.2    Hellhammer, D.H.3
  • 64
    • 0031807854 scopus 로고    scopus 로고
    • Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis
    • Plotsky PM, Owens MJ, Nemeroff CB,. Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis. Psychiatr Clin North Am 1998; 21: 293-307.
    • (1998) Psychiatr Clin North Am , vol.21 , pp. 293-307
    • Plotsky, P.M.1    Owens, M.J.2    Nemeroff, C.B.3
  • 65
    • 0028358435 scopus 로고
    • Dexamethasone resistance among nonhuman primates associated with a selective decrease of glucocorticoid receptors in the hippocampus and a history of social instability
    • Brooke SM, de Haas-Johnson AM, Kaplan J, Manuck SB, Salposky RM,. Dexamethasone resistance among nonhuman primates associated with a selective decrease of glucocorticoid receptors in the hippocampus and a history of social instability. Neuroendocrinology 1994; 60: 134-140. (Pubitemid 24222461)
    • (1994) Neuroendocrinology , vol.60 , Issue.2 , pp. 134-140
    • Brooke, S.M.1    De Haas-Johnson, A.M.2    Kaplan, J.R.3    Manuck, S.B.4    Sapolsky, R.M.5
  • 66
    • 0026473129 scopus 로고
    • Immune disorders in depression: Higher T helper/T suppressor-cytotoxic cell ratio
    • Maes M, Stevens W, DeClerck L, et al. Immune disorders in depression: higher T helper/T suppressor-cytotoxic cell ratio. Acta Psychiatr Scand 1992; 86: 423-431.
    • (1992) Acta Psychiatr Scand , vol.86 , pp. 423-431
    • Maes, M.1    Stevens, W.2    Declerck, L.3
  • 67
    • 33750097170 scopus 로고    scopus 로고
    • Prevalence of autoantibodies and the risk of autoimmune thyroid disease in children with chronic hepatitis C virus infection treated with interferon
    • Gehring S, Kullmer U, Koeppelmann S, Gerner P, Wintermeyer P, Wirth S,. Prevalence of autoantibodies and the risk of autoimmune thyroid disease in children with chronic hepatitis C virus infection treated with interferon-α. World J Gastroenterol 2006; 12: 5787-5792. (Pubitemid 44594245)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.36 , pp. 5787-5792
    • Gehring, S.1    Kullmer, U.2    Koeppelman, S.3    Gerner, P.4    Wintermeyer, P.5    Wirth, S.6
  • 68
    • 0029058604 scopus 로고
    • Autoimmunity and thyroid function in patients with chronic active hepatitis treated with recombinant interferon alpha-2a
    • Preziati D, La Rosa L, Covini G, et al. Autoimmunity and thyroid function in patients with chronic active hepatitis treated with recombinant interferon alpha-2a. Eur J Endocrinol 1995; 132: 587-593.
    • (1995) Eur J Endocrinol , vol.132 , pp. 587-593
    • Preziati, D.1    La Rosa, L.2    Covini, G.3
  • 70
    • 2342630638 scopus 로고    scopus 로고
    • Suicidal ideation during interferon-2b and ribavirin treatment of patients with chronic hepatitis C
    • DOI 10.1016/j.genhosppsych.2004.01.003, PII S0163834304000179
    • Dieperink E, Ho SB, Tetrick L, Thuras P, Dua K, Willenbring ML,. Suicidal ideation during interferon-alpha2b and ribavirin treatment of patients with chronic hepatitis C. Gen Hosp Psychiatry 2004; 26: 237-240. (Pubitemid 38581929)
    • (2004) General Hospital Psychiatry , vol.26 , Issue.3 , pp. 237-240
    • Dieperink, E.1    Ho, S.B.2    Tetrick, L.3    Thuras, P.4    Dua, K.5    Willenbring, M.L.6
  • 71
    • 38049153269 scopus 로고    scopus 로고
    • Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha
    • Loftis JM, Huckans M, Ruimy S, Hinrichs DJ, Hauser P,. Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha. Neurosci Lett 2008; 430: 264-268.
    • (2008) Neurosci Lett , vol.430 , pp. 264-268
    • Loftis, J.M.1    Huckans, M.2    Ruimy, S.3    Hinrichs, D.J.4    Hauser, P.5
  • 74
    • 71149101597 scopus 로고    scopus 로고
    • Platelet serotonin (5-HT) levels in interferon-treated patients with hepatitis C and its possible association with interferon-induced depression
    • Schäfer A, Scheurlen M, Seufert J, et al. Platelet serotonin (5-HT) levels in interferon-treated patients with hepatitis C and its possible association with interferon-induced depression. J Hepatol 2010; 52: 10-15.
    • (2010) J Hepatol , vol.52 , pp. 10-15
    • Schäfer, A.1    Scheurlen, M.2    Seufert, J.3


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