Infection of primary human macrophages with hepatitis C virus in vitro: Induction of tumour necrosis factor-α and interleukin 8

Journal of General Virology

Volumn 85, Issue 1, 2004, Pages 47-59

  Radkowski, Marek ^a,c   Bednarska, Agnieszka ^b   Horban, Andrzej ^b   Stanczak, Janusz ^b   Wilkinson, Jeffrey ^c   Adair, Debra M ^c   Nowicki, Marek ^d   Rakela, Jorge ^c   Laskus, Tomasz ^c  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b SP ZOZ Wojewodzki Szpital Zakazny Centrum Diagnostyki i Terapii AIDS Warszawa   (Poland)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; PROTEIN P70; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DONOR; ENZYME IMMUNOASSAY; ENZYME SPECIFICITY; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC ANALYSIS; HEPATITIS C; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INCUBATION TIME; INFECTION SENSITIVITY; MACROPHAGE; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEQUENCE ANALYSIS; SERODIAGNOSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; SUPERNATANT; VIRUS DETECTION; VIRUS GENE; VIRUS MORPHOLOGY; VIRUS PATHOGENESIS;

CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYTOKINES; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERLEUKIN-8; MACROPHAGES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, VIRAL; TUMOR NECROSIS FACTOR-ALPHA;

HEPATITIS C VIRUS; RNA VIRUSES;

EID: 1642544601     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.19491-0     Document Type: Article

References (39)

1. Auffermann-Gretzinger, S., Keeffe, E. B. & Levy, S. (2001). Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection. Blood 97, 3171-3176.
2. Bain, C., Fatmi, A., Zoulim, F., Zarski, J. P., Trepo, C. & Inchauspe, G. (2001). Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology 120, 512-524.
3. Becker, S., Quay, J. & Soukup, J. (1991). Cytokine (tumor necrosis factor, IL-6, and IL-8) production by respiratory syncytial virus-infected human alveolar macrophages. J Immunol 147, 4307-4312.
4. Beld, M., Penning, M., Lukashov, V., McMorrow, M., Roos, M., Pakker, N., van den Hoek, A. & Goudsmit, J. (1998). Evidence that both HIV and HIV-induced immunodeficiency enhance HCV replication among HCV seroconverters. Virology 244, 504-512.
5. Bronowicki, J. P., Loriot, M. A., Thiers, V., Grignon, Y., Zignego, A. L. & Brechot, C. (1998). Hepatitis C virus persistence in human hematopoietic cells injected into SCID mice. Hepatology 28, 211-218.
6. Choo, Q. L., Richman, K. H., Han, J. H., Berger, K., Lee, C., Dong, C., Gallegos, C., Coit, D., Medina-Selby, R., Barr, P. J., Weiner, A. J., Bradley, D. W., Kuo, G. & Houghton, M. (1991). Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci U S A 88, 2451-2455.
7. Cook, E. B., Stahl, J. L., Lowe, L., Chen, R., Morgan, E., Wilson, J., Varro, R., Chan, A., Graziano, F. M. & Barney, N. P. (2001). Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergics. J Immunol Methods 254, 109-118.
8. Daar, E. S., Lynn, H., Donfield, S., Gomperts, E., O'Brien, S. J., Hilgartner, M. W., Hoots, W. K., Chernoff, D., Arkin, S., Wong, W. Y. & Winkler, C. A. (2001). Hepatitis C virus load is associated with human immunodeficiency virus type 1 disease progression in hemophiliacs. J Infect Dis 183, 589-595.
9. Greub, G., Ledergerber, B., Battegay, M., Grob, P., Perrin, L., Furrer, H., Burgisser, P., Erb, P., Boggian, K., Piffaretti, J. C., Hirschel, B., Janin, P., Francioli, P., Flepp, M. & Telenti, A. (2000). Clinical progression, survival, and immune recovery during antiretroviral therapy in patients with HIV-1 and hepatitis C virus coinfection: the Swiss HIV Cohort Study. Lancet 356, 1800-1805.
10. Herbein, G. & O'Brien, W. A. (2000). Tumor necrosis factor (TNF)-alpha and TNF receptors in viral pathogenesis. Proc Soc Exp Biol Med 223, 241-257.
11. Hilfenhaus, J., Groner, A., Nowak, T. & Weimer, T. (1997). Analysis of human plasma products: polymerase chain reaction does not discriminate between live and inactivated viruses. Transfusion 37, 935-940.
12. Kanto, T., Hayashi, N., Takehara, T., Tatsumi, T., Kuzushita, N., Ito, A., Sasaki, Y., Kasahara, A. & Hori, M. (1999). Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. J Immunol 162, 5584-5591.
13. Khabar, K. S., Al-Zoghaibi, F., Al-Ahdal, M. N., Murayama, T., Dhalla, M., Mukaida, N., Taha, M., Al-Sedairy, S. T., Siddiqui, Y., Kessie, G. & Matsushima, K. (1997). The alpha chemokine, interleukin 8, inhibits the antiviral action of interferon alpha. J Exp Med 186, 1077-1085.
14. Lane, B. R., Lore, K., Bock, P. J., Andersson, J., Coffey, M. J., Strieter, R. M. & Markovitz, D. M. (2001). Interleukin-8 stimulates human immunodeficiency virus type 1 replication and is a potential new target for antiretroviral therapy. J Virol 75, 8195-8202.
15. Lanford, R. E., Sureau, C., Jacob, J. R., White, R. & Fuerst, T. R. (1994). Demonstration of in vitro infection of chimpanzee hepatocytes with hepatitis C virus using strand-specific RT/PCR. Virology 202, 606-614.
16. Laskus, T., Radkowski, M., Wang, L. F., Vargas, H. & Rakela, J. (1997). Lack of evidence for hepatitis G virus replication in the livers of patients coinfected with hepatitis C and G viruses. J Virol 71, 7804-7806.
17. Laskus, T., Radkowski, M., Wang, L. F., Jang, S. J., Vargas, H. & Rakela, J. (1998). Hepatitis C virus quasispecies in patients infected with HIV-1: correlation with extrahepatic viral replication. Virology 248, 164-171.
18. Laskus, T., Radkowski, M., Piasek, A., Nowicki, M., Horban, A., Cianciara, J. & Rakela, J. (2000a). Hepatitis C virus in lymphoid cells of patients coinfected with human immunodeficiency virus type 1: evidence of active replication in monocytes/macrophages and lymphocytes. J Infect Dis 181, 442-448.
19. Laskus, T., Radkowski, M., Wang, L. F., Nowicki, M. & Rakela, J. (2000b). Uneven distribution of hepatitis C virus quasispecies in tissues from subjects with end-stage liver disease: confounding effect of viral adsorption and mounting evidence for the presence of low-level extrahepatic replication. J Virol 74, 1014-1017.
20. Laskus, T., Wang, L. F., Radkowski, M., Vargas, H., Nowicki, M., Wilkinson, J. & Rakela, J. (2001). Exposure of hepatitis C virus (HCV) RNA-positive recipients to HCV RNA-positive blood donors results in rapid predominance of a single donor strain and exclusion and/or suppression of the recipient strain. J Virol 75, 2059-2066.
21. Lehmann, C., Sprenger, H., Nain, M., Bacher, M. & Gemsa, D. (1996). Infection of macrophages by influenza A virus: characteristics of tumour necrosis factor-alpha (TNT alpha) gene expression. Res Virol 147, 123-130.
22. Lerat, H., Rumin, S., Habersetzer, F., Berby, F., Trabaud, M. A., Trepo, C. & Inchauspe, G. (1998). In vivo tropism of hepatitis C virus genomic sequences in hematopoietic cells: influence of viral load, viral genotype, and cell phenotype. Blood 91, 3841-3849.
23. Mahe, Y., Mukaida, N., Kuno, K., Akiyama, M., Ikeda, N., Matsushima, K. & Murakami, S. (1991). Hepatitis B virus X protein transactivates human interleukin-8 gene through acting on nuclear factor κB and CCAAT/enhancer-binding protein-like cis-elements. J Biol Chem 266, 13759-13763.
24. Mogensen, S. C. (1979). Role of macrophages in natural resistance to virus infections. Microbiol Rev 43, 1-26.
25. Mori, N., Mukaida, N., Ballard, D. W., Matsushima, K. & Yamamoto, N. (1998). Human T-cell leukemia virus type I Tax transactivates human interleukin 8 gene through acting concurrently on AP-1 and nuclear factor-kappa B-like sites. Cancer Res 58, 3993-4000.
26. Mukaida, N. (2000). Interleukin-8: an expanding universe beyond neutrophil chemotaxis and activation. Int J Hematol 72, 391-398.
27. Murayama, T., Kuno, K., Jisaki, F., Obuchi, M., Sakamuro, D., Furukawa, T., Mukaida, N. & Matsushima, K. (1994). Enhancement human cytomegalovirus replication in a human lung fibroblast cell line by interleukin-8. J Virol 68, 7582-7585.
28. Murayama, T., Ohara, Y., Obuchi, M., Khabar, K. S., Higashi, H., Mukaida, N. & Matsushima, K. (1997). Human cytomegalovirus induces interleukin-8 production by a human monocytic cell line, THP-1, through acting concurrently on AP-1- and NF-κB-binding sites of the interleukin-8 gene. J Virol 71, 5692-5695.
29. Nakajima, N., Hijikata, M., Yoshikura, H. & Shimizu, Y. K. (1996). Characterization of long-term cultures of hepatitis C virus. J Virol 70, 3325-3329.
30. Navas, S., Martin, J., Quiroga, J. A., Castillo, I. & Carreno, V. (1998). Genetic diversity and tissue compartmentalization of the hepatitis C virus genome in blood mononuclear cells, liver, and serum from chronic hepatitis C patients. J Virol 72, 1640-1646.
31. Nowak, T., Niedrig, M., Bernhardt, D. & Hilfenhaus, J. (1993). Inactivation of HIV, HBV, HCV related viruses and other viruses in human plasma derivatives by pasteurisation. Dev Biol Stand 81, 169-176.
32. Oliver, K. G., Kettman, J. R. & Fulton, R. J. (1998). Multiplexed analysis of human cytokines by use of the FlowMetrix system. Clin Chem 44, 2057-2060.
33. Polyak, S. J., Khabar, K. S., Paschal, D. M., Ezelle, H. J., Duverlie, G., Barber, G. N., Levy, D. E., Mukaida, N. & Gretch, D. R. (2001a). Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. J Virol 75, 6095-6106.
34. Polyak, S. J., Khabar, K. S., Rezeiq, M. & Gretch, D. R. (2001b). Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy. J Virol 75, 6209-6211.
35. Sansonno, D., Iacobelli, A. R., Cornacchiulo, V., Iodice, G. & Dammacco, F. (1996). Detection of hepatitis C virus (HCV) proteins by immunofluorescence and HCV RNA genomic sequences by non-isotopic in situ hybridization in bone marrow and peripheral blood mononuclear cells of chronically HCV-infected patients. Clin Exp Immunol 103, 414-421.
36. Shimizu, Y. K., Purcell, R. H. & Yoshikura, H. (1993). Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro. Proc Natl Acad Sci U S A 90, 6037-6041.
37. Shimizu, Y. K., Igarashi, H., Kanematu, T., Fujiwara, K., Wong, D. C., Purcell, R. H. & Yoshikura, H. (1997). Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees. J Virol 71, 5769-5773.
38. Simmonds, P., Holmes, E. C., Cha, T. A., Chan, S. W., McOmish, F., Irvine, B., Beall, E., Yap, P. L., Kolberg, J. & Urdea, M. S. (1993). Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region. J Gen Virol 74, 2391-2399.
39. Thomas, D. L., Rich, J. D., Schuman, P., Smith, D. K., Astemborski, J. A., Nolt, K. R. & Klein, R. S. (2001). Multicenter evaluation of hepatitis C RNA levels among female injection drug users. J Infect Dis 183, 973-976.