Prevalence and significance of neurocognitive dysfunction in hepatitis C in the absence of correlated risk factors

Hepatology

Volumn 41, Issue 4, 2005, Pages 801-808

  McAndrews, Mary Pat ^a,b   Farcnik, Karl ^a   Carlen, Peter ^a   Damyanovich, Andrei ^a   Mrkonjic, Mirela ^a   Jones, Susan ^a   Heathcote, E Jenny ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; N ACETYLASPARTIC ACID;

ADULT; ARTICLE; CENTRAL NERVOUS SYSTEM; CHRONIC HEPATITIS; CLINICAL ARTICLE; CLINICAL FEATURE; COGNITION; COGNITIVE DEFECT; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; DISEASE SEVERITY; FATIGUE; HEPATITIS C; HUMAN; HUMAN TISSUE; LEARNING; LEARNING DISORDER; MORBIDITY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; WHITE MATTER;

ADULT; CASE-CONTROL STUDIES; COGNITION DISORDERS; COHORT STUDIES; DEPRESSION; FATIGUE; HEPATITIS C, CHRONIC; HUMANS; LEARNING DISORDERS; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGED; NERVOUS SYSTEM DISEASES; NEUROPSYCHOLOGICAL TESTS; PREVALENCE;

EID: 16244405882     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20635     Document Type: Article

References (34)

1. Forton DM, Allsop JM, Main J, Foster GR, Thomas HC, Taylor-Robinson SD. Evidence for a cerebral effect of the hepatitis C virus. Lancet 2001;358:38-39.
2. Forton DM, Thomas HC, Murphy CA, Allsop JM, Foster GR, Main J, et al. Hepatitis C and cognitive impairment in a cohort of patients with mild liver disease. HEPATOLOGY 2002;35:433-439.
3. Cordoba J, Flavia M, Jacas C, Sauleda S, Esteban JI, Vargas V, et al. Quality of life and cognitive function in hepatitis C at different stages of liver disease. J Hepatol 2003;39:231-238.
4. Hilsabeck RC, Perry W, Hassanein TI. Neuropsychological impairment in patients with chronic hepatitis C. HEPATOLOGY 2002;35:440-446.
5. Hilsabeck RC, Hassanein TI, Carlson MD, Ziebler EA, Perry W. Cognitive functioning and psychiatric symptomatology in patients with chronic hepatitis C. J Internat Neuropsychol Soc 2003;9:847-854.
6. Kramer L, Bauer E, Funk G, Hofer J, Jessner W, Steindl-Munda P, et al. Subclinical impairment of brain function in chronic hepatitis C infection. J Hepatol 2002;37:349-354.
7. Forton DM, Taylor-Robinson S, Karayiannis P, Thomas H. Identification of brain-specific quasispecies variants of hepatitis C virus (HCV) consistent with viral replication in the central nervous system. HEPATOLOGY 2000;32:269A.
8. Radkowski M, Wilkinson J, Nowicki M, Adair D, Vargas H, Ingui C, et al. Search for hepatitis C virus negative-strand RNA sequences and analysis of viral sequences in the central nervous system: evidence of replication. J Virol 2002;76:600-608.
9. Moss HB, Tarter RE, Yao JK, Van Thiel DH. Subclinical hepatic encephalopathy: relationship between neuropsychological deficits and standard laboratory tests assessing hepatic status. Arch Clin Neuropsychol 1992;7:419-429.
10. Huda A, Guze BH, Thomas A, Bugbee M, Fairbanks L, Strouse T, et al. Clinical correlation of neuropsychological tests with 1H magnetic resonance spectroscopy in hepatic encephalopathy. Psychosom Med 1998;60:550-556.
11. Quero JC, Hartmann IJC, Hop WCJ, Schalm SW. The diagnosis of subclinical hepatic encephalopathy in patients with cirrhosis using neuropsychological tests and automated electroencephalogram analysis. HEPATOLOGY 1996;24:556-560.
12. Saxena N, Bhatia M, Joshi YK, Garg PK, Tandon RK. Auditory P300 event-related potentials and number connection test for evaluation of subclinical hepatic encephalopathy in patients with cirrhosis of the liver: a follow-up study. J Gastroenterol Hepatol 2001;16:322-327.
13. Taylor-Robinson SD, Sargentoni J, Oatridge A Bryant, DJ, Hajnal JV, Marcus CD, et al. MR imaging and spectroscopy of the basal ganglia in chronic liver disease: correlation of T1-weighted contrast measurements with abnormalities in proton and phosphorus-31 MR spectra. Metab Brain Dis 1996;11:249-268.
14. Taylor-Robinson SD, Buckley C, Changani KK, Hodgson HJ, Bell JD. Cerebral proton and phosphorus-31 magnetic resonance spectroscopy in patients with subclinical hepatic encephalopathy. Liver 1999;19:289-298.
15. Lezak MD. Neuropsychological Assessment. 3rd ed. New York: Oxford University Press, 1995.
16. Schwartz JE, Jandorf L, Krupp, LB. The measurement of fatigue: a new instrument. J Psychosomatic Res 1993;37:753-762.
17. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30:672-679.
18. Maddrey WC. Safety of combination interferon alfa-2b/ribavirin therapy in chronic hepatitis C-relapsed and treatment-naive patients. Semin Liver Dis 1999;19(Suppl 1):67-75.
19. Gohier B, Goeb JL, Rannou-Dubas K, Rouchard E, Cales, P, Garre JB. Hepatitis C, alpha interferon, anxiety and depression disorders: a prospective study of 71 patients. World J Biol Psychiatry 2003;4:115-118.
20. Wedding D, Faust D. Clinical judgment and decision making in neuropsychology. Arch Clin Neuropsychol 1989;4:233-265.
21. DeStefano N, Matthews PM, Arnold DL. Reversible decreases in N-acetylaspartate after acute brain injury. Magn Reson Med 1995;34:721-727.
22. Vermathen P, Ende F, Laxer KD, Walker JA, Knowlton RC, Barbaro NM, et al. Temporal lobectomy for epilepsy: recovery of the contralateral hippocampus measured by 1H MRS. Neurol 2002;59:633-636.
23. Chaudhuri A, Behan PO. In vivo magnetic resonance spectroscopy in chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids 2004;71:181-183.
24. Ernst T, Chang L. Effect of aging on brain metabolism in antiretroviral-naïve HIV patients. AIDS 2004;18(Suppl 1):S61-S67.
25. Babb SM, Ke Y, Lange N, Kaufman MJ, Renshaw PF, Cohen BM. Oral choline increases choline metabolites in human brain. Psychiatry Res 2004;130:1-9.
26. Fanning L, Loane J, Kenny-Walsh E, Sheehan M, Whelton M, Kirwan W, et al. Tissue viral load variability in chronic hepatitis C. Am J Gastroenterol 2001;96:3384-3389.
27. Regev, A, Berho M, Jeffers LJ, Milikowski C, Molina EG, Pyrsopoulos NT, et al. Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol 2002;97:2614-2618.
28. Groeneweg M, Moerland W, Quero JC, Hop WC, Krabbe PF, Schalm SW. Screening of subclinical hepatic encephalopathy. J Hepatol 2000;32:748-753.
29. Lee JH, Seo DW, Lee YS, Kim ST, Mun CW, Lim TH, et al. Proton magnetic resonance spectroscopy (1H-MRS) findings for the brain in patients with liver cirrhosis reflect the hepatic functional reserve. Am J Gastroenterol 1999;94:2206-2213.
30. Foster GR, Foldin RD, Thomas HC. Chronic hepatitis C virus infection causes a significant reduction in quality of life in the absence of cirrhosis. HEPATOLOGY 1998;27:209-212.
31. Bonkovsky HL, Woolley JM. Reduction in health-related quality of life in chronic hepatitis C and improvement with interferon therapy. The Consensus Interferon Study Group. HEPATOLOGY 1999;29:264-270.
32. Ware JE Jr, Bayliss MS, Mannocchia M, Davis GL. Health-related quality of life in chronic hepatitis C: impact of disease and treatment response. The Interventional Therapy Group. HEPATOLOGY 1999;30:550-555.
33. Cordoba J, Reyes J, Esteban JI, Hernandez JM. Labeling may be an important cause of reduced quality of life in chronic hepatitis C. Am J Gastorenterol 2003;98:226-227.
34. Schwarzinger M, Dewedar S, Rekacewicz C, Abd Elaziz KM, Fontanet A, Carrat F, et al. Chronic hepatitis C virus infection: does it really impact health-related quality of life? A study in rural Egypt. HEPATOLOGY 2004;40:1434-1441.