Quality control of multidrug resistance assays in adult acute leukemia: Correlation between assays for P-glycoprotein expression and activity

Blood

Volumn 87, Issue 11, 1996, Pages 4809-4816

  Broxterman, H J ^a   Sonneveld, P ^b   Feller, N ^b   Ossenkoppele, G J ^b   Wahrer D C R ^b   Eekman, C A ^b   Schoester, M ^b   Lankelma, J ^b   Pinedo, H M ^b   Lowenberg B ^b   Schuurhuis, G J ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DAUNORUBICIN; GLYCOPROTEIN P; TRITIUM; VERAPAMIL; VINCRISTINE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; DIAGNOSTIC ACCURACY; FLUORESCENCE; GENE EXPRESSION REGULATION; GOOD LABORATORY PRACTICE; HUMAN; ISOTOPE LABELING; MAJOR CLINICAL STUDY; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN DETERMINATION;

EID: 9344264652     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.11.4809.bloodjournal87114809     Document Type: Article

References (37)

1. Peterson RHF, Biedler JL: Plasma membrane proteins and glycoproteins from chinese hamster cells sensitive and resistant to actinomycin D. J Supramolecular Structure 9:289, 1978
2. Bradley G, Juranka PF, Ling V: Mechanisms of multidrug resistance. Biochim Biophys Acta 948:87, 1988
3. Geller RB, Karp JE: Acute adult leukemia: A need for continued translational research. Blood 84:3980, 1994
4. Pirker R, Wallner J, Geissler K, Linkesch W, Haas OA, Bettelheim P, Hopfner M, Scherrer R, Valent P, Havelec L. Ludwig H, Lechner K: mdr1 gene expression and treatment outcome in acute myeloid leukaemia. J Natl Cancer Inst 83:708, 1991
5. Nooter K, Sonneveld P: Clinical relevance of P-glycoprotein expression in haematological malignancies. Leuk Res 18:233, 1994
6. Zhou D-C, Marie J-P, Suberville A-M, Zittoun R: Relevance of mdr1 gene expression in acute myeloid leukemia and comparison of different diagnostic methods. Leukemia 6:879, 1992
7. Campos L, Guyotat D, Archimbaud E, Calmard-Oriol P, Tsuruo T, Troncy J, Treille D, Fiere D: Clinical significance of multidrug resistance P-glycoprotein expression on acute non-lymphoblastic leukemia cells at diagnosis. Blood 79:473, 1992
8. Holmes JA, West RR: The effect of MDR1 gene expression on outcome in acute myeloblastic leukemia. Br J Cancer 69:382, 1994
9. Haber DA: Multidrug resistance (MDR1) in leukemia: Is it time to test? Blood 79:295, 1992
10. Hedley DW: Flow cytometric assays of anticancer drug resistance, in: Clinical Flow Cytometry Series. Ann NY Acad Sci 677:341, 1993
11. Broxterman HJ, Kuiper CM, Schuurhuis GJ, Tsuruo T, Pinedo HM, Lankelma J: Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein. Biochem Pharmacol 37:2389, 1988
12. Versantvoort CHM, Broxterman HJ, Feller N, Dekker H, Kuiper CM, Lankelma J: Probing daunorubicin accumulation defects in non-P-glycoprotein expressing multidrug-resistant cell lines using digitonin. Int J Cancer 50:906, 1992
13. Feller N, Kuiper CM, Lankelma J, Ruhdal JK, Scheper RJ, Pinedo HM, Broxterman HJ: Functional detection of MDR1/P170 and MRP/P190 mediated multidrug resistance in tumor cells by flow cytometry. Br J Cancer 72:543, 1995
14. Maslak P, Hegewisch-Becker S, Godfrey L, Andreeff M: Flow cytometric determination of the multidrug-resistant phenotype in acute leukemia. Cytometry 17:84, 1994
15. Schuurhuis GJ, Broxterman HJ, Ossenkoppele GJ, Baak JPA, Eekman CA, Kuiper CM, Feller N, van Heijningen THM, Klumper E, Pieters R, Lankelma J, Pinedo HM: Functional multidrug resistance phenotype associated with combined overexpression of Pgp/ MDR1 and MRP together with 1- -D-arabinofuranosyl-cytosine sensitivity may predict clinical response in acute myeloid leukemia. Clin Cancer Res 1:81, 1995
16. Pilarski LM, Belch AR: Circulating monoclonal B cells expressing P-glycoprotein may be a reservoir of multidrug-resistant disease in multiple myeloma. Blood 83:724, 1994
17. Versantvoort CHM, Broxterman HJ, Lankelma J, Feller N, Pinedo HM: Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells. Biochem Pharmacol 48:1129, 1994
18. Arceci RJ: Clinical significance of P-glycoprotein in multidrug resistance malignancies. Blood 81:2215, 1993
19. Guerci A, Merlin JL, Missoum N, Feldmann L, Marchal S, Witz F, Rose C, Guerci O: Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flow cytometry. Blood 85:2147, 1995
20. Longo R, Bensi L, Vecchi A, Messora C, Sacchi S: P-glycoprotein expression in acute myeloblastic leukemia analyzed by immunocytochemistry and flow cytometry. Leuk Lymphoma 17:121, 1995
21. Marie JP: P-glycoprotein in adult hematologic malignancies. Hematol Oncol Clin North Am 9:239, 1995
22. Beck WT, Grogan TM, Willman CL, Cordon-Cardo C, Parham DM, Kuttesch JF, Andreeff M, Bates SE, Berard CW, Boyett JM, Brophy NA, Broxterman HJ, Chan HSL, Dalton WS, Dietel M, Fojo AT, Gascoyne RD, Head D, Houghton PJ, Srivastava DK, Lehnert M, Leith CP, Paietta E, Pavelic ZP, Rimsza L, Roninson IB, Sikic BI, Twentyman PR, Warnke R, Weinstein RW: The St. Jude Workshop on methods to detect p-glycoprotein-associated multidrug resistance: Findings and consensus recommendations. Cancer Res 1996 (in press)
23. Broxterman HJ, Lankelma J, Pinedo HM: How to probe clinical tumor samples for P-glycoprotein and multidrug resistance protein. Eur J Cancer 1996 (in press)
24. Xie SX-Y, Robb D, Chow S, Hedley DW: Discordant P-glycoprotein expression and transport function in acute myeloid leukemia. Leukemia 9:1882, 1995
25. Shi T, Wrin J, Reeder J, Liu D, Ring DB: High-affinity monoclonal antibodies against P-glycoprotein. Clin Immunol Immunopathol 76:44, 1995
26. Sonneveld P, Schoester M, de Leeuw K: Clinical modulation of multidrug resistance in multiple myeloma: Effect of cyclosporine on resistant tumor cells. J Clin Oncol 12:1584, 1994
27. Young SW, Poole RC, Hudson AT, Halestrap AP, Denton RM, Tavaré JM: Effects of tyrosine kinase inhibitors on protein kinase-independent systems. FEBS Lett 316:278, 1993
28. Broxterman HJ, Versantvoort CHM: Pharmacology of drug transport in multidrug resistant tumor cells, in Kellen JA (ed): Alternative Mechanisms of Multidrug Resistance in Cancer. Boston, MA, Birkhäuser, 1995, p 67
29. -" cases. Blood 86:2329, 1995
30. + acute myeloid leukemia cells. Blood 82:3157, 1993
31. + acute myeloblastic leukemia/acute lymphoblastic leukemia. Blood 82:3445, 1993
32. Lum BL, Gosland MP: MDR expression in normal tissues. Pharmacologic implications for the clinical use of P-glycoprotein inhibitors. Hematol Oncol Clin North Am 9:319, 1995
33. Schuurhuis GJ, van Heijningen THM, Cervantes A, Pinedo HM, de Lange JHM, Keizer HG, Broxterman HJ, Baak JPA, Lankelma J: Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells. Br J Cancer 68:898, 1993
34. Broxterman HJ, Jansen G, Linn SC, Lankelma J: The impact of transport-associated resistance in anticancer chemotherapy, in Georgopapadakou NH (ed): Drug Transport in Antimicrobial and Anticancer Chemotherapy. New York, NY, Dekker, 1995, p 21
35. List AF, Spier C, Greer J, Wolff S, Hutter J, Dorr R, Salmon S, Futscher B, Baier M, Dalton WS: Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia. J Clin Oncol 11:1652, 1993
36. Flens MJ, Izquierdo MA, Scheffer GL, Fritz JM, Meijer CJLM, Scheper RJ, Zaman GJR: Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies. Cancer Res 54:4557, 1994
37. Feller N, Broxterman HJ, Währer DCR, Pinedo HM: ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): No inhibition by intracellular glutathione depletion. FEBS Lett 368:385, 1995