-
2
-
-
0017162520
-
Adipose tissue cellularity in human obesity
-
Hirsch, J., and B. Batchelor. 1976. Adipose tissue cellularity in human obesity. Clin. Endocrinol. Metab. 5: 299-311.
-
(1976)
Clin. Endocrinol. Metab.
, vol.5
, pp. 299-311
-
-
Hirsch, J.1
Batchelor, B.2
-
3
-
-
33847250516
-
Skp2 controls adipocyte proliferation during the development of obesity
-
DOI 10.1074/jbc.M608144200
-
Sakai, T., H. Sakaue, T. Nakamura, M. Okada, Y. Matsuki, E. Watanabe, R. Hiramatsu, K. Nakayama, K. I. Nakayama, and M. Kasuga. 2007. Skp2 controls adipocyte proliferation during the development of obesity. J. Biol. Chem. 282: 2038-2046. (Pubitemid 47076733)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.3
, pp. 2038-2046
-
-
Sakai, T.1
Sakaue, H.2
Nakamura, T.3
Okada, M.4
Matsuki, Y.5
Watanabe, E.6
Hiramatsu, R.7
Nakayama, K.8
Nakayama, K.I.9
Kasuga, M.10
-
4
-
-
33845886915
-
Abdominal obesity and metabolic syndrome
-
DOI 10.1038/nature05488, PII NATURE05488
-
Despres, J. P., and I. Lemieux. 2006. Abdominal obesity and metabolic syndrome. Nature. 444: 881-887. (Pubitemid 46024995)
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 881-887
-
-
Despres, J.-P.1
Lemieux, I.2
-
5
-
-
33845864967
-
Adipocytes as regulators of energy balance and glucose homeostasis
-
Rosen, E. D., and B. M. Spiegelman. 2006. Adipocytes as regulators of energy balance and glucose homeostasis. Nature. 444: 847-853.
-
(2006)
Nature
, vol.444
, pp. 847-853
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
6
-
-
0031037111
-
Regulation of adipose cell number in man
-
Prins, J. B., and S. O'Rahilly. 1997. Regulation of adipose cell number in man. Clin. Sci. (Lond.). 92: 3-11. (Pubitemid 27033005)
-
(1997)
Clinical Science
, vol.92
, Issue.1
, pp. 3-11
-
-
Prins, J.B.1
O'Rahilly, S.2
-
7
-
-
0035074176
-
Comparison of anti-apoptotic signalling by the insulin receptor and IGF-I receptor in preadipocytes and adipocytes
-
DOI 10.1016/S0898-6568(01)00130-9, PII S0898656801001309
-
Urso, B., C. U. Niesler, S. O'Rahilly, and K. Siddle. 2001. Comparison of anti-apoptotic signalling by the insulin receptor and IGF-I receptor in preadipocytes and adipocytes. Cell. Signal. 13: 279-285. (Pubitemid 32295947)
-
(2001)
Cellular Signalling
, vol.13
, Issue.4
, pp. 279-285
-
-
Urso, B.1
Niesler, C.U.2
O'Rahilly, S.3
Siddle, K.4
-
8
-
-
0034741270
-
TNFalpha induces and insulin inhibits caspase 3-dependent adipocyte apoptosis
-
Qian, H., D. B. Hausman, M. M. Compton, R. J. Martin, M. A. Della-Fera, D. L. Hartzell, and C. A. Baile. 2001. TNFalpha induces and insulin inhibits caspase 3-dependent adipocyte apoptosis. Biochem. Biophys. Res. Commun. 284: 1176-1183.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.284
, pp. 1176-1183
-
-
Qian, H.1
Hausman, D.B.2
Compton, M.M.3
Martin, R.J.4
Della-Fera, M.A.5
Hartzell, D.L.6
Baile, C.A.7
-
9
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn, B. B., and J. S. Flier. 2000. Obesity and insulin resistance. J. Clin. Invest. 106: 473-481.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
10
-
-
0035038782
-
Mechanisms of nutritional and hormonal regulation of lipogenesis
-
DOI 10.1093/embo-reports/kve071
-
Kersten, S. 2001. Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep. 2: 282-286. (Pubitemid 32401521)
-
(2001)
EMBO Reports
, vol.2
, Issue.4
, pp. 282-286
-
-
Kersten, S.1
-
11
-
-
0036179818
-
A pilot study of long-term effects of a novel obesity treatment: Omentectomy in connection with adjustable gastric banding
-
DOI 10.1038/sj/ijo/0801871
-
Thorne, A., F. Lonnqvist, J. Apelman, G. Hellers, and P. Arner. 2002. A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding. Int. J. Obes. Relat. Metab. Disord. 26: 193-199. (Pubitemid 34151196)
-
(2002)
International Journal of Obesity
, vol.26
, Issue.2
, pp. 193-199
-
-
Thorne, A.1
Lonnqvist, F.2
Apelman, J.3
Hellers, G.4
Arner, P.5
-
12
-
-
0032564421
-
Insulin depletion leads to adipose-specific cell death in obese but not lean mice
-
Loftus, T. M., F. P. Kuhajda, and M. D. Lane. 1998. Insulin depletion leads to adipose-specific cell death in obese but not lean mice. Proc. Natl. Acad. Sci. USA. 95: 14168-14172.
-
(1998)
Proc. Natl. Acad. Sci. USA.
, vol.95
, pp. 14168-14172
-
-
Loftus, T.M.1
Kuhajda, F.P.2
Lane, M.D.3
-
13
-
-
0036068133
-
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance
-
Bluher, M., M. D. Michael, O. D. Peroni, K. Ueki, N. Carter, B. B. Kahn, and C. R. Kahn. 2002. Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Dev. Cell. 3: 25-38.
-
(2002)
Dev. Cell.
, vol.3
, pp. 25-38
-
-
Bluher, M.1
Michael, M.D.2
Peroni, O.D.3
Ueki, K.4
Carter, N.5
Kahn, B.B.6
Kahn, C.R.7
-
14
-
-
33244464562
-
Critical nodes in signalling pathways: Insights into insulin action
-
Taniguchi, C. M., B. Emanuelli, and C. R. Kahn. 2006. Critical nodes in signalling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol. 7: 85-96.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
15
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning, B. D., and L. C. Cantley. 2007. AKT/PKB signaling: navigating downstream. Cell. 129: 1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
16
-
-
0033515625
-
A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain
-
Brodbeck, D., P. Cron, and B. A. Hemmings. 1999. A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain. J. Biol. Chem. 274: 9133-9136.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9133-9136
-
-
Brodbeck, D.1
Cron, P.2
Hemmings, B.A.3
-
17
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)
-
Cho, H., J. Mu, J. K. Kim, J. L. Thorvaldsen, Q. Chu, E. B. Crenshaw 3rd, K. H. Kaestner, M. S. Bartolomei, G. I. Shulman, and M. J. Birnbaum. 2001. Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science. 292: 1728-1731.
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw III, E.B.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
18
-
-
0035914388
-
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
-
Cho, H., J. L. Thorvaldsen, Q. Chu, F. Feng, and M. J. Birnbaum. 2001. Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 276: 38349-38352.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.L.2
Chu, Q.3
Feng, F.4
Birnbaum, M.J.5
-
19
-
-
23144449547
-
Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis
-
Tschopp, O., Z. Z. Yang, D. Brodbeck, B. A. Dummler, M. Hemmings-Mieszczak, T. Watanabe, T. Michaelis, J. Frahm, and B. A. Hemmings. 2005. Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis. Development. 132: 2943-2954.
-
(2005)
Development.
, vol.132
, pp. 2943-2954
-
-
Tschopp, O.1
Yang, Z.Z.2
Brodbeck, D.3
Dummler, B.A.4
Hemmings-Mieszczak, M.5
Watanabe, T.6
Michaelis, T.7
Frahm, J.8
Hemmings, B.A.9
-
20
-
-
34547533470
-
Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation
-
Juntilla, M. M., J. A. Wofford, M. J. Birnbaum, J. C. Rathmell, and G. A. Koretzky. 2007. Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation. Proc. Natl. Acad. Sci. USA. 104: 12105-12110.
-
(2007)
Proc. Natl. Acad. Sci. USA.
, vol.104
, pp. 12105-12110
-
-
Juntilla, M.M.1
Wofford, J.A.2
Birnbaum, M.J.3
Rathmell, J.C.4
Koretzky, G.A.5
-
21
-
-
33845996191
-
Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions
-
Liu, X., Y. Shi, M. J. Birnbaum, K. Ye, R. De Jong, T. Oltersdorf, V. L. Giranda, and Y. Luo. 2006. Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions. J. Biol. Chem. 281: 31380-31388.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 31380-31388
-
-
Liu, X.1
Shi, Y.2
Birnbaum, M.J.3
Ye, K.4
De Jong, R.5
Oltersdorf, T.6
Giranda, V.L.7
Luo, Y.8
-
22
-
-
0037341276
-
Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: Potential role of p38 in the downregulation of GLUT4 expression
-
Carlson, C. J., S. Koterski, R. J. Sciotti, G. B. Poccard, and C. M. Rondinone. 2003. Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression. Diabetes. 52: 634-641.
-
(2003)
Diabetes
, vol.52
, pp. 634-641
-
-
Carlson, C.J.1
Koterski, S.2
Sciotti, R.J.3
Poccard, G.B.4
Rondinone, C.M.5
-
23
-
-
19944433322
-
The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis
-
Bost, F., M. Aouadi, L. Caron, P. Even, N. Belmonte, M. Prot, C. Dani, P. Hofman, G. Pages, J. Pouyssegur, et al. 2005. The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. Diabetes. 54: 402-411.
-
(2005)
Diabetes
, vol.54
, pp. 402-411
-
-
Bost, F.1
Aouadi, M.2
Caron, L.3
Even, P.4
Belmonte, N.5
Prot, M.6
Dani, C.7
Hofman, P.8
Pages, G.9
Pouyssegur, J.10
-
24
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi, J., G. Tuncman, L. Chang, C. Z. Gorgun, K. T. Uysal, K. Maeda, M. Karin, and G. S. Hotamisligil. 2002. A central role for JNK in obesity and insulin resistance. Nature. 420: 333-336.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
25
-
-
33746101818
-
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
-
Tuncman, G., J. Hirosumi, G. Solinas, L. Chang, M. Karin, and G. S. Hotamisligil. 2006. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc. Natl. Acad. Sci. USA. 103: 10741-10746.
-
(2006)
Proc. Natl. Acad. Sci. USA.
, vol.103
, pp. 10741-10746
-
-
Tuncman, G.1
Hirosumi, J.2
Solinas, G.3
Chang, L.4
Karin, M.5
Hotamisligil, G.S.6
-
26
-
-
0142093519
-
Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients
-
Koistinen, H. A., A. V. Chibalin, and J. R. Zierath. 2003. Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients. Diabetologia. 46: 1324-1328.
-
(2003)
Diabetologia
, vol.46
, pp. 1324-1328
-
-
Koistinen, H.A.1
Chibalin, A.V.2
Zierath, J.R.3
-
27
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis, R. J. 2000. Signal transduction by the JNK group of MAP kinases. Cell. 103: 239-252.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
28
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang, D. D., C. Y. Kuan, A. J. Whitmarsh, M. Rincon, T. S. Zheng, R. J. Davis, P. Rakic, and R. A. Flavell. 1997. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature. 389: 865-870.
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincon, M.4
Zheng, T.S.5
Davis, R.J.6
Rakic, P.7
Flavell, R.A.8
-
29
-
-
0029070887
-
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
-
Minden, A., A. Lin, F. X. Claret, A. Abo, and M. Karin. 1995. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell. 81: 1147-1157.
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.X.3
Abo, A.4
Karin, M.5
-
30
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia, Z., M. Dickens, J. Raingeaud, R. J. Davis, and M. E. Greenberg. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270: 1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
31
-
-
48149085566
-
Silencing Jnk1 and Jnk2 accelerates basal lipolysis and promotes fatty acid reesterification in mouse adipocytes
-
Rozo, A. V., R. Vijayvargia, H. R. Weiss, and H. Ruan. 2008. Silencing Jnk1 and Jnk2 accelerates basal lipolysis and promotes fatty acid reesterification in mouse adipocytes. Diabetologia. 51: 1493-1504.
-
(2008)
Diabetologia
, vol.51
, pp. 1493-1504
-
-
Rozo, A.V.1
Vijayvargia, R.2
Weiss, H.R.3
Ruan, H.4
-
32
-
-
0032080022
-
CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor
-
DOI 10.1093/emboj/17.9.2526
-
Inohara, N., T. Koseki, S. Chen, X. Wu, and G. Nunez. 1998. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. EMBO J. 17: 2526-2533. (Pubitemid 28221188)
-
(1998)
EMBO Journal
, vol.17
, Issue.9
, pp. 2526-2533
-
-
Inohara, N.1
Koseki, T.2
Chen, S.3
Wu, X.4
Nunez, G.5
-
33
-
-
0037442523
-
Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family
-
DOI 10.1042/BJ20020656
-
Liang, L., M. Zhao, Z. Xu, K. K. Yokoyama, and T. Li. 2003. Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family. Biochem. J. 370: 195-203. (Pubitemid 36259432)
-
(2003)
Biochemical Journal
, vol.370
, Issue.1
, pp. 195-203
-
-
Liang, L.1
Zhao, M.2
Xu, Z.3
Yokoyama, K.K.4
Li, T.5
-
34
-
-
0041353552
-
Cidea-deficient mice have lean phenotype and are resistant to obesity
-
Zhou, Z., S. Yon Toh, Z. Chen, K. Guo, C. P. Ng, S. Ponniah, S. C. Lin, W. Hong, and P. Li. 2003. Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat. Genet. 35: 49-56. (Pubitemid 37048595)
-
(2003)
Nature Genetics
, vol.35
, Issue.1
, pp. 49-56
-
-
Zhou, Z.1
Toh, S.Y.2
Chen, Z.3
Guo, K.4
Ng, C.P.5
Ponniah, S.6
Lin, S.-C.7
Hong, W.8
Li, P.9
-
35
-
-
34948895555
-
Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation
-
DOI 10.2337/db07-0040
-
Li, J. Z., J. Ye, B. Xue, J. Qi, J. Zhang, Z. Zhou, Q. Li, Z. Wen, and P. Li. 2007. Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes. 56: 2523-2532. (Pubitemid 47523259)
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2523-2532
-
-
Li, J.Z.1
Ye, J.2
Xue, B.3
Qi, J.4
Zhang, J.5
Zhou, Z.6
Li, Q.7
Wen, Z.8
Li, P.9
-
36
-
-
48749103552
-
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets
-
Nishino, N., Y. Tamori, S. Tateya, T. Kawaguchi, T. Shibakusa, W. Mizunoya, K. Inoue, R. Kitazawa, S. Kitazawa, Y. Matsuki, et al. 2008. FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J. Clin. Invest. 118: 2808-2821.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2808-2821
-
-
Nishino, N.1
Tamori, Y.2
Tateya, S.3
Kawaguchi, T.4
Shibakusa, T.5
Mizunoya, W.6
Inoue, K.7
Kitazawa, R.8
Kitazawa, S.9
Matsuki, Y.10
-
37
-
-
51449123610
-
Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice
-
Toh, S. Y., J. Gong, G. Du, J. Z. Li, S. Yang, J. Ye, H. Yao, Y. Zhang, B. Xue, Q. Li, et al. 2008. Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS ONE. 3: e2890.
-
(2008)
PLoS ONE
, vol.3
-
-
Toh, S.Y.1
Gong, J.2
Du, G.3
Li, J.Z.4
Yang, S.5
Ye, J.6
Yao, H.7
Zhang, Y.8
Xue, B.9
Li, Q.10
-
38
-
-
20044395797
-
A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity
-
DOI 10.2337/diabetes.54.6.1726
-
Nordstrom, E. A., M. Ryden, E. C. Backlund, I. Dahlman, M. Kaaman, L. Blomqvist, B. Cannon, J. Nedergaard, and P. Arner. 2005. A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity. Diabetes. 54: 1726-1734. (Pubitemid 40770763)
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1726-1734
-
-
Nordstrom, E.A.1
Ryden, M.2
Backlund, E.C.3
Dahlman, I.4
Kaaman, M.5
Blomqvist, L.6
Cannon, B.7
Nedergaard, J.8
Arner, P.9
-
39
-
-
36849040036
-
Relations of adipose tissue CIDEA gene expression to basal metabolic rate, energy restriction, and obesity: Population-based and dietary intervention studies
-
DOI 10.1210/jc.2007-1136
-
Gummesson, A., M. Jernas, P. A. Svensson, I. Larsson, C. A. Glad, E. Schele, L. Gripeteg, K. Sjoholm, T. C. Lystig, L. Sjostrom, et al. 2007. Relations of adipose tissue CIDEA gene expression to basal metabolic rate, energy restriction, and obesity: population-based and dietary intervention studies. J. Clin. Endocrinol. Metab. 92: 4759-4765. (Pubitemid 350223457)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.12
, pp. 4759-4765
-
-
Gummesson, A.1
Jernas, M.2
Svensson, P.-A.3
Larsson, I.4
Glad, C.A.M.5
Schele, E.6
Gripeteg, L.7
Sjoholm, K.8
Lystig, T.C.9
Sjostrom, L.10
Carlsson, B.11
Fagerberg, B.12
Carlsson, L.M.S.13
-
40
-
-
25844434336
-
The CIDEA gene V115F polymorphism is associated with obesity in Swedish subjects
-
DOI 10.2337/diabetes.54.10.3032
-
Dahlman, I., M. Kaaman, H. Jiao, J. Kere, M. Laakso, and P. Arner. 2005. The CIDEA gene V115F polymorphism is associated with obesity in Swedish subjects. Diabetes. 54: 3032-3034. (Pubitemid 41401104)
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 3032-3034
-
-
Dahlman, I.1
Kaaman, M.2
Jiao, H.3
Kere, J.4
Laakso, M.5
Arner, P.6
-
41
-
-
39849089906
-
Cell death-inducing DNA fragmentation factor alpha-like effector A (CIDEA) gene V115F (G→T) polymorphism is associated with phenotypes of metabolic syndrome in Japanese men
-
DOI 10.1016/j.metabol.2007.11.011, PII S0026049507004052
-
Zhang, L., K. Miyaki, T. Nakayama, and M. Muramatsu. 2008. Cell death-inducing DNA fragmentation factor alpha-like effector A (CIDEA) gene V115F (G→T) polymorphism is associated with phenotypes of metabolic syndrome in Japanese men. Metabolism. 57: 502-505. (Pubitemid 351317964)
-
(2008)
Metabolism: Clinical and Experimental
, vol.57
, Issue.4
, pp. 502-505
-
-
Zhang, L.1
Miyaki, K.2
Nakayama, T.3
Muramatsu, M.4
-
42
-
-
70450220107
-
Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC
-
Rubio-Cabezas, O., V. Puri, I. Murano, V. Saudek, R. K. Semple, S. Dash, C. S. Hyden, W. Bottomley, C. Vigouroux, J. Magre, et al. 2009. Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol. Med. 1: 280-287.
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 280-287
-
-
Rubio-Cabezas, O.1
Puri, V.2
Murano, I.3
Saudek, V.4
Semple, R.K.5
Dash, S.6
Hyden, C.S.7
Bottomley, W.8
Vigouroux, C.9
Magre, J.10
-
43
-
-
36348940037
-
Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage
-
Puri, V., S. Konda, S. Ranjit, M. Aouadi, A. Chawla, M. Chouinard, A. Chakladar, and M. P. Czech. 2007. Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage. J. Biol. Chem. 282: 34213-34218.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 34213-34218
-
-
Puri, V.1
Konda, S.2
Ranjit, S.3
Aouadi, M.4
Chawla, A.5
Chouinard, M.6
Chakladar, A.7
Czech, M.P.8
-
44
-
-
44949130214
-
Fat-specific protein 27 regulates storage of triacylglycerol
-
Keller, P., J. T. Petrie, P. De Rose, I. Gerin, W. S. Wright, S. H. Chiang, A. R. Nielsen, C. P. Fischer, B. K. Pedersen, and O. A. Macdougald. 2008. Fat-specific protein 27 regulates storage of triacylglycerol. J. Biol. Chem. 283: 14355-14365.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14355-14365
-
-
Keller, P.1
Petrie, J.T.2
De Rose, P.3
Gerin, I.4
Wright, W.S.5
Chiang, S.H.6
Nielsen, A.R.7
Fischer, C.P.8
Pedersen, B.K.9
Macdougald, O.A.10
-
45
-
-
77953516567
-
Differential roles of CIDEA and CIDEC in insulin-induced antiapoptosis and lipid droplet formation in human adipocytes
-
Ito, M., M. Nagasawa, T. Hara, T. Ide, and K. Murakami. 2010. Differential roles of CIDEA and CIDEC in insulin-induced antiapoptosis and lipid droplet formation in human adipocytes. J. Lipid Res. 51: 1676-1684.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1676-1684
-
-
Ito, M.1
Nagasawa, M.2
Hara, T.3
Ide, T.4
Murakami, K.5
-
46
-
-
3042743988
-
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
-
DOI 10.1158/0008-5472.CAN-04-0343
-
Yang, L., H. C. Dan, M. Sun, Q. Liu, X. M. Sun, R. I. Feldman, A. D. Hamilton, M. Polokoff, S. V. Nicosia, M. Herlyn, et al. 2004. Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res. 64: 4394-4399. (Pubitemid 38856907)
-
(2004)
Cancer Research
, vol.64
, Issue.13
, pp. 4394-4399
-
-
Yang, L.1
Dan, H.C.2
Sun, M.3
Liu, Q.4
Sun, X.-M.5
Feldman, R.I.6
Hamilton, A.D.7
Polokoff, M.8
Nicosia, S.V.9
Herlyn, M.10
Sebti, S.M.11
Cheng, J.Q.12
-
47
-
-
41649112075
-
Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death
-
Kim, J. Y., K. Liu, S. Zhou, K. Tillison, Y. Wu, and C. M. Smas. 2008. Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death. Am. J. Physiol. Endocrinol. Metab. 294: E654-E667.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
-
-
Kim, J.Y.1
Liu, K.2
Zhou, S.3
Tillison, K.4
Wu, Y.5
Smas, C.M.6
-
48
-
-
0037059834
-
Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis
-
Reusch, J. E., and D. J. Klemm. 2002. Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis. J. Biol. Chem. 277: 1426-1432.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1426-1432
-
-
Reusch, J.E.1
Klemm, D.J.2
-
49
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
DOI 10.1073/pnas.251194298
-
Bennett, B. L., D. T. Sasaki, B. W. Murray, E. C. O'Leary, S. T. Sakata, W. Xu, J. C. Leisten, A. Motiwala, S. Pierce, Y. Satoh, et al. 2001. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. USA. 98: 13681-13686. (Pubitemid 33115958)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.24
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
Bhagwat, S.S.11
Manning, A.M.12
Anderson, D.W.13
-
50
-
-
58149473797
-
siRNA screening reveals JNK2 as an evolutionary conserved regulator of triglyceride homeostasis
-
Grimard, V., J. Massier, D. Richter, D. Schwudke, Y. Kalaidzidis, E. Fava, A. Hermetter, and C. Thiele. 2008. siRNA screening reveals JNK2 as an evolutionary conserved regulator of triglyceride homeostasis. J. Lipid Res. 49: 2427-2440.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 2427-2440
-
-
Grimard, V.1
Massier, J.2
Richter, D.3
Schwudke, D.4
Kalaidzidis, Y.5
Fava, E.6
Hermetter, A.7
Thiele, C.8
-
51
-
-
77957832253
-
Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway
-
Choi, S. M., D. F. Tucker, D. N. Gross, R. M. Easton, L. M. DiPilato, A. S. Dean, B. R. Monks, and M. J. Birnbaum. 2010. Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway. Mol. Cell. Biol. 30: 5009-5020.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5009-5020
-
-
Choi, S.M.1
Tucker, D.F.2
Gross, D.N.3
Easton, R.M.4
DiPilato, L.M.5
Dean, A.S.6
Monks, B.R.7
Birnbaum, M.J.8
-
52
-
-
0036319163
-
Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro
-
McTernan, P. G., A. L. Harte, L. A. Anderson, A. Green, S. A. Smith, J. C. Holder, A. H. Barnett, M. C. Eggo, and S. Kumar. 2002. Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro. Diabetes. 51: 1493-1498. (Pubitemid 34826616)
-
(2002)
Diabetes
, vol.51
, Issue.5
, pp. 1493-1498
-
-
McTernan, P.G.1
Harte, A.L.2
Anderson, L.A.3
Green, A.4
Smith, S.A.5
Holder, J.C.6
Barnett, A.H.7
Eggo, M.C.8
Kumar, S.9
-
53
-
-
77951229616
-
Fatspecific protein 27 undergoes ubiquitin-dependent degradation regulated by triacylglycerol synthesis and lipid droplet formation
-
Nian, Z., Z. Sun, L. Yu, S. Y. Toh, J. Sang, and P. Li. 2010. Fatspecific protein 27 undergoes ubiquitin-dependent degradation regulated by triacylglycerol synthesis and lipid droplet formation. J. Biol. Chem. 285: 9604-9615.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9604-9615
-
-
Nian, Z.1
Sun, Z.2
Yu, L.3
Toh, S.Y.4
Sang, J.5
Li, P.6
-
54
-
-
0032562112
-
Insulin differentially regulates SAPKs/JNKs and ERKs in CHO cells overexpressing human insulin receptors
-
DOI 10.1006/bbrc.1998.8181
-
Desbois-Mouthon, C., M. J. Blivet-Van Eggelpoel, M. Auclair, G. Cherqui, J. Capeau, and M. Caron. 1998. Insulin differentially regulates SAPKs/JNKs and ERKs in CHO cells overexpressing human insulin receptors. Biochem. Biophys. Res. Commun. 243: 765-770. (Pubitemid 28414154)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.243
, Issue.3
, pp. 765-770
-
-
Desbois-Mouthon, C.1
Blivet-Van, E.M.-J.2
Auclair, M.3
Cherqui, G.4
Capeau, J.5
Caron, M.6
-
55
-
-
0037474274
-
c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade
-
Lee, Y. H., J. Giraud, R. J. Davis, and M. F. White. 2003. c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade. J. Biol. Chem. 278: 2896-2902.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2896-2902
-
-
Lee, Y.H.1
Giraud, J.2
Davis, R.J.3
White, M.F.4
-
56
-
-
33644750396
-
2-terminal kinase pathways in inflammation and origin of obesity and diabetes
-
DOI 10.2337/diabetes.54.suppl-2.S73
-
Hotamisligil, G. S. 2005. Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes. Diabetes. 54 (Suppl. 2): S73-S78. (Pubitemid 43343334)
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Hotamisligil, G.S.1
|