Conditional inactivation of the CXCR4 receptor in osteoprecursors reduces postnatal bone formation due to impaired osteoblast development

Journal of Biological Chemistry

Volumn 286, Issue 30, 2011, Pages 26794-26805

  Zhu, Wei ^a,b   Liang, Gang ^a   Huang, Zhiping ^a   Doty, Stephen B ^a   Boskey, Adele L ^a,b  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE DEVELOPMENT; BONE FORMATION; BONE MINERAL DENSITY; BONE MORPHOGENIC PROTEIN; BONE TISSUE; CHEMOKINE RECEPTORS; CHONDROCYTES; COLLAGEN MATRICES; CORTICAL BONE; ENDOGENOUS SIGNALING; GROWTH PLATE; IN-VIVO; MESENCHYMAL PROGENITORS; MINERAL APPOSITION RATE; OSTEOBLAST DIFFERENTIATION; OSTEOBLASTIC CELLS; OSTEOCALCIN; OSTEOGENIC DIFFERENTIATION; OSTERIX; PRIMARY CULTURE; TYPE I COLLAGEN; UNDERLYING MECHANISM;

AMINO ACIDS; CELL CULTURE; COLLAGEN; MAMMALS; SIGNALING; SILICATE MINERALS; TISSUE;

BONE;

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 6; CHEMOKINE RECEPTOR CXCR4; COLLAGEN; COLLAGEN TYPE 1ALPHA1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMAD PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE CELL; BONE DENSITY; BONE DEVELOPMENT; BONE MASS; BONE TISSUE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DIFFERENTIATION; EPIPHYSIS; GENE DELETION; GROWTH PLATE; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOBLAST; PERINATAL PERIOD; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SKELETON; TRABECULAR BONE;

ANIMALS; BONE DENSITY; BONE DISEASES, METABOLIC; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 6; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROCYTES; COLLAGEN TYPE I; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 3; OSTEOBLASTS; OSTEOGENESIS; RECEPTORS, CXCR4; SMAD PROTEINS;

MUS;

EID: 79960663308     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.250985     Document Type: Article

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