The role of HIV-related chemokine receptors and chemokines in human erythropoiesis in vitro

Stem Cells

Volumn 18, Issue 2, 2000, Pages 128-138

  Majka, Marcin ^a   Ratajczak, Janina ^a   Lee, Benhur ^b   Honczarenko, Marek ^b   Douglas, Ray ^b   Kowalska, M Anna ^c   Silberstein, Leslie ^b   Gewirtz, Alan M ^a   Ratajczak, Mariusz Z ^a,d  

^a Laboratory Medicine   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

CCR5; Chemokine receptors; Chemokines; CXCR4; Hematopoiesis; HIV; Stromal derived factor 1 (SDF 1)

Indexed keywords

CALCIUM; CD34 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPHORIN A; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; RANTES; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG;

ARTICLE; BURST FORMING UNIT E; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL MATURATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; HEMATOPOIESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IN VITRO STUDY;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0034024211     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.18-2-128     Document Type: Article

References (36)

1. Cairns JS, D'Souza MP. Chemokines and HIV-1 second receptors: the therapeutic connection. Nat Med 1998;4:563-568.
2. Fauci AS. Host factors and the pathogenesis of HIV-induced disease. Nature 1996;384:529-534.
3. Hoxie JA. Hematologic manifestations of AIDS. In Hoffman R, Benz EJ, Shatill SJ et al., eds. Hematology Basic Principles and Practice. New York: Churchill Livingstone, 1995;2171-2200.
4. Lee B, Doranz BJ, Ratajczak MZ et al. An intricate web: chemokine receptors, HIV-1 and hematopoiesis. STEM CELLS 1998;16:79-88.
5. Moses A, Nelson J, Bagby GC. The influence of human immunodeficiency virus-1 on hematopoiesis. Blood 1998;91:1479-1495.
6. Rollins BJ. Chemokines. Blood 1997;90:909-928.
7. Lee B, Ratajczak J, Doms RW et al. Coreceptor/chemokine receptor expression on human hematopoietic cells: biological implications for HIV-1 infection. Blood 1999;93:1145-1156.
8. Broxmeyer HE, Sherry B, Cooper S et al. Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. J Immunol 1993;150:3448-3458.
9. Su S, Mukaida N, Wang J et al. Inhibition of immature erythroid progenitor cell proliferation by macrophage inflammatory protein-1α by interacting mainly with a C-C chemokine receptor, CCR1. Blood 1997;90:605-611.
10. + cells isolated from cord blood and bone marrow to MIP-1α and the expression of MIP-1α receptors on these immature cells. STEM CELLS 1998;16:349-356.
11. + progenitors to peripheral blood. J Exp Med 1997;185 111-120.
12. Bleul CC Fuhlbridge RC, Casanovas JM et al. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 1996;184:1101-1109.
13. Kim CH, Broxmeyer HE. In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment. Blood 1998;91:100-110.
14. Ma Q, Jores D, Borghesani PR et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4 and SDF-1 deficient mice. Proc Natl Acad Sci USA 1998;95:9448-9453.
15. + hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood 1998;91:4523-4530.
16. Nagasawa T, Hirota S, Tachibana K et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 1998;382:635-638.
17. Zou Y, Kottmann AH, Kurod M et al. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998;393:595-599.
18. Ratajczak J, Zhang Q, Pertusini E et al. The role of insulin (INS) and insulin like growth factor-I (IGF-I) in regulating human erythropoiesis. Studies in vitro under serum free conditions - comparison to other cytokines and growth factors. Leukemia 1998;12:371-381.
19. + cells. Folia Histochem Cytobiol 1998;36:55-60.
20. low phenotype identifies a marrow cell population highly enriched for human hematopoietic stem cells. Leukemia 1998;12:942-950.
21. Kowalska MA, Ratajczak J, Hoxie J et al. Platelet and megakaryocytes express the HIV co-receptor CXCR4 on their surface but do not respond to stromal derived factor (SDF)-1. Br J Haematol 1999;104:220-229.
22. + splenic T cells after CD28 receptor ligation. J Immunol 1995;154:985-997.
23. Rocca JDG, Biesen T, Daaka Y et al. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. J Biol Chem 1998;272:19125-19132.
24. De Jong MO, Wagemaker G, Wognum AW. Separation of myeloid and erythroid progenitors based on expression of CD34 and c-kit. Blood 1995;86:4076-4085.
25. + cells and megakaryoblasts secrete β-chemokines; implications for infectability by M-tropic human immunodeficiency virus (R5 HIV). J Clin Invest 1999;104:1739-1749.
26. Dutt P, Wang JF, Groopman JE. Stromal cell-derived factor-1α and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: a potential mechanism for cooperative induction of chemotaxis. J Immunol 1998;161:3652-3658.
27. Cashman JD, Eaves CJ, Sarris AH et al. MCP-1, not MIP-1α, is the endogenous chemokine that cooperates with TGF-β to inhibit the cycling of primitive normal but not leukemic (CML) progenitors in long-term human marrow cultures. Blood 1998;92:2338-2344.
28. Cook DN, Beck MA, Coffman TM et al. Requirement of MIP-1α for an inflammatory response to viral infection. Science 1995;269:1583-1585.
29. Mantel C, Kim YJ, Cooper S et al. Polymerization of murine macrophage inflammatory protein 1α inactivates its myelosuppressive effects in vitro: the active form is monomer. Proc Natl Acad Sci USA 1993;90:2232-2236.
30. - cells in stroma-derived soluble factors, interleukin-3, and macrophage inflammatory protein-1α maintains not only myeloid but also lymphoid progenitors in a novel switch culture assay. Blood 1998;91:4516-4522.
31. Patel VP, Kreider BL, Li Y et al. Molecular and functional chracterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors. J Exp Med 1997;185:1163-1172.
32. Sanchez X, Cousins-Hodges B, Aguilar T et al. Activation of HIV-1 coreceptor (CXCR4) mediates myelosuppression. J Biol Chem 1997;272:27529-27531.
33. Gewirtz AM, Zhang J, Ratajczak J et al. Chemokine regulation of human megakaryocytopoiesis. Blood 1995;86:2559-2567.
34. + hematopoietic progenitor cells by human immunodeficiency virus 1 or gp 120 mediated by endogenous transforming growth factor β1. J Exp Med 1996;183:99-108.
35. Wang JF, Liu ZY, Groopman JF. The β-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood 1998;92:756-764.
36. Doranz BJ, Govit-Ferbas K, Sharron MP et al. A small molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J Exp Med 1997;186:1395-1400.