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Volumn 46, Issue 9, 2011, Pages 762-767

Aldose reductase pathway contributes to vulnerability of aging myocardium to ischemic injury

Author keywords

Aging hearts; Aldose reductase; Cardiac function; Myocardial ischemic injury; Polyol pathway

Indexed keywords

ALDEHYDE REDUCTASE; CP 407 711; ENZYME INHIBITOR; IDITOL DEHYDROGENASE; UNCLASSIFIED DRUG; ZOPOLRESTAT;

EID: 79960626595     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2011.05.001     Document Type: Article
Times cited : (18)

References (52)
  • 2
    • 0032873703 scopus 로고    scopus 로고
    • Ischemia-reperfusion in the adult mouse heart influence of age
    • Azhar G., Gao W., Liu L., Wei J.Y. Ischemia-reperfusion in the adult mouse heart influence of age. Experimental Gerontology 1999, 34:699-714.
    • (1999) Experimental Gerontology , vol.34 , pp. 699-714
    • Azhar, G.1    Gao, W.2    Liu, L.3    Wei, J.Y.4
  • 3
    • 0032704549 scopus 로고    scopus 로고
    • Influence of age on hypoxia/reoxygenation-induced DNA fragmentation and bcl-2, bcl-xl, bax and fas in the rat heart and brain
    • Azhar G., Liu L., Zhang X., Wei J.Y. Influence of age on hypoxia/reoxygenation-induced DNA fragmentation and bcl-2, bcl-xl, bax and fas in the rat heart and brain. Mechanisms of Ageing and Development 1999, 112:5-25.
    • (1999) Mechanisms of Ageing and Development , vol.112 , pp. 5-25
    • Azhar, G.1    Liu, L.2    Zhang, X.3    Wei, J.Y.4
  • 5
    • 0024325693 scopus 로고
    • Myocardial metabolism in ischemic heart disease: basic principles and application to imaging by positron emission tomography
    • Camici P., Ferrannini E., Opie L.H. Myocardial metabolism in ischemic heart disease: basic principles and application to imaging by positron emission tomography. Progress in Cardiovascular Diseases 1989, 32:217-238.
    • (1989) Progress in Cardiovascular Diseases , vol.32 , pp. 217-238
    • Camici, P.1    Ferrannini, E.2    Opie, L.H.3
  • 6
    • 0027310528 scopus 로고
    • Myocardial GLUT-4 glucose transporter protein levels of rats decline with advancing age
    • Cartee G.D. Myocardial GLUT-4 glucose transporter protein levels of rats decline with advancing age. Journal of Gerontology 1993, 48:B168-B170.
    • (1993) Journal of Gerontology , vol.48
    • Cartee, G.D.1
  • 7
    • 8344266747 scopus 로고    scopus 로고
    • Interaction between the polyol pathway and non-enzymatic glycation on mesangial cell gene expression
    • Dan Q., Wong R.L., Yin S., Chung S.K., Chung S.S., Lam K.S. Interaction between the polyol pathway and non-enzymatic glycation on mesangial cell gene expression. Nephron Experimental Nephrology 2004, 98:e89-e99.
    • (2004) Nephron Experimental Nephrology , vol.98
    • Dan, Q.1    Wong, R.L.2    Yin, S.3    Chung, S.K.4    Chung, S.S.5    Lam, K.S.6
  • 9
    • 0032128428 scopus 로고    scopus 로고
    • Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation
    • Headrick J.P. Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation. Journal of Molecular and Cellular Cardiology 1998, 30:1415-1430.
    • (1998) Journal of Molecular and Cellular Cardiology , vol.30 , pp. 1415-1430
    • Headrick, J.P.1
  • 10
    • 33747069158 scopus 로고    scopus 로고
    • Aldose reductase-deficient mice are protected from delayed motor nerve conduction velocity, increased c-Jun NH2-terminal kinase activation, depletion of reduced glutathione, increased superoxide accumulation, and DNA damage
    • Ho E.C., Lam K.S., Chen Y.S., Yip J.C., Arvindakshan M., Yamagishi S., Yagihashi S., Oates P.J., Ellery C.A., Chung S.S., Chung S.K. Aldose reductase-deficient mice are protected from delayed motor nerve conduction velocity, increased c-Jun NH2-terminal kinase activation, depletion of reduced glutathione, increased superoxide accumulation, and DNA damage. Diabetes 2006, 55:1946-1953.
    • (2006) Diabetes , vol.55 , pp. 1946-1953
    • Ho, E.C.1    Lam, K.S.2    Chen, Y.S.3    Yip, J.C.4    Arvindakshan, M.5    Yamagishi, S.6    Yagihashi, S.7    Oates, P.J.8    Ellery, C.A.9    Chung, S.S.10    Chung, S.K.11
  • 12
    • 0642272495 scopus 로고    scopus 로고
    • Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium
    • Hwang Y.C., Bakr S., Ellery C.A., Oates P.J., Ramasamy R. Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium. The FASEB Journal 2003, 17:2331-2333.
    • (2003) The FASEB Journal , vol.17 , pp. 2331-2333
    • Hwang, Y.C.1    Bakr, S.2    Ellery, C.A.3    Oates, P.J.4    Ramasamy, R.5
  • 14
    • 18144381538 scopus 로고    scopus 로고
    • Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury
    • Hwang Y.C., Shaw S., Kaneko M., Redd H., Marrero M.B., Ramasamy R. Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury. The FASEB Journal 2005, 19:795-797.
    • (2005) The FASEB Journal , vol.19 , pp. 795-797
    • Hwang, Y.C.1    Shaw, S.2    Kaneko, M.3    Redd, H.4    Marrero, M.B.5    Ramasamy, R.6
  • 15
    • 0036174476 scopus 로고    scopus 로고
    • Acute and chronic adaptation to hemodynamic overload and ischemia in the aged heart
    • Isoyama S., Nitta-Komatsubara Y. Acute and chronic adaptation to hemodynamic overload and ischemia in the aged heart. Heart Failure Reviews 2002, 7:63-69.
    • (2002) Heart Failure Reviews , vol.7 , pp. 63-69
    • Isoyama, S.1    Nitta-Komatsubara, Y.2
  • 19
    • 0037469206 scopus 로고    scopus 로고
    • Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging
    • Lakatta E.G. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging. Circulation 2003, 107:490-497.
    • (2003) Circulation , vol.107 , pp. 490-497
    • Lakatta, E.G.1
  • 20
    • 0037422592 scopus 로고    scopus 로고
    • Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease
    • Lakatta E.G., Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation 2003, 107:139-146.
    • (2003) Circulation , vol.107 , pp. 139-146
    • Lakatta, E.G.1    Levy, D.2
  • 21
    • 0037458070 scopus 로고    scopus 로고
    • Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease
    • Lakatta E.G., Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease. Circulation 2003, 107:346-354.
    • (2003) Circulation , vol.107 , pp. 346-354
    • Lakatta, E.G.1    Levy, D.2
  • 24
    • 0036890121 scopus 로고    scopus 로고
    • Age-related difference in myocardial function and inflammation in a rat model of myocardial ischemia-reperfusion
    • Liu P., Xu B., Cavalieri T.A., Hock C.E. Age-related difference in myocardial function and inflammation in a rat model of myocardial ischemia-reperfusion. Cardiovascular Research 2002, 56:443-453.
    • (2002) Cardiovascular Research , vol.56 , pp. 443-453
    • Liu, P.1    Xu, B.2    Cavalieri, T.A.3    Hock, C.E.4
  • 25
    • 0031024750 scopus 로고    scopus 로고
    • Glucose metabolism in the ischemic heart
    • Lopaschuk G.D., Stanley W.C. Glucose metabolism in the ischemic heart. Circulation 1997, 95:313-315.
    • (1997) Circulation , vol.95 , pp. 313-315
    • Lopaschuk, G.D.1    Stanley, W.C.2
  • 26
    • 0024262853 scopus 로고
    • Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine
    • Lopaschuk G.D., Wall S.R., Olley P.M., Davies N.J. Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine. Circulation Research 1988, 63:1036-1043.
    • (1988) Circulation Research , vol.63 , pp. 1036-1043
    • Lopaschuk, G.D.1    Wall, S.R.2    Olley, P.M.3    Davies, N.J.4
  • 29
    • 0025967888 scopus 로고
    • Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners
    • Mylari B.L., Larson E.R., Beyer T.A., Zembrowski W.J., Aldinger C.E., Dee M.F., Siegel T.W., Singleton D.H. Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners. Journal of Medicinal Chemistry 1991, 34:108-122.
    • (1991) Journal of Medicinal Chemistry , vol.34 , pp. 108-122
    • Mylari, B.L.1    Larson, E.R.2    Beyer, T.A.3    Zembrowski, W.J.4    Aldinger, C.E.5    Dee, M.F.6    Siegel, T.W.7    Singleton, D.H.8
  • 30
    • 0041888262 scopus 로고    scopus 로고
    • Design and synthesis of a novel family of triazine-based inhibitors of sorbitol dehydrogenase with oral activity: 1-[4-[3R,5S-dimethyl-4-(4-methyl-[1,3,5]triazin-2-yl)-piperazin-1-yl]-[1,3,5]triazin-2-yl]-(R) ethanol
    • Mylari B.L., Withbroe G.J., Beebe D.A., Brackett N.S., Conn E.L., Coutcher J.B., Oates P.J., Zembrowski W.J. Design and synthesis of a novel family of triazine-based inhibitors of sorbitol dehydrogenase with oral activity: 1-[4-[3R,5S-dimethyl-4-(4-methyl-[1,3,5]triazin-2-yl)-piperazin-1-yl]-[1,3,5]triazin-2-yl]-(R) ethanol. Bioorganic & Medicinal Chemistry 2003, 11:4179-4188.
    • (2003) Bioorganic & Medicinal Chemistry , vol.11 , pp. 4179-4188
    • Mylari, B.L.1    Withbroe, G.J.2    Beebe, D.A.3    Brackett, N.S.4    Conn, E.L.5    Coutcher, J.B.6    Oates, P.J.7    Zembrowski, W.J.8
  • 32
    • 1842389677 scopus 로고
    • Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle
    • Neely J.R., Morgan H.E. Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. Annual Review of Physiology 1974, 36:413-459.
    • (1974) Annual Review of Physiology , vol.36 , pp. 413-459
    • Neely, J.R.1    Morgan, H.E.2
  • 34
    • 0030941732 scopus 로고    scopus 로고
    • Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury
    • Ramasamy R., Oates P.J., Schaefer S. Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury. Diabetes 1997, 46:292-300.
    • (1997) Diabetes , vol.46 , pp. 292-300
    • Ramasamy, R.1    Oates, P.J.2    Schaefer, S.3
  • 35
    • 33750867930 scopus 로고    scopus 로고
    • Metabolic effects of aldose reductase inhibition during low-flow ischemia and reperfusion
    • Ramasamy R., Trueblood N., Schaefer S. Metabolic effects of aldose reductase inhibition during low-flow ischemia and reperfusion. The American Journal of Physiology 1998, 275:H195-H203.
    • (1998) The American Journal of Physiology , vol.275
    • Ramasamy, R.1    Trueblood, N.2    Schaefer, S.3
  • 36
    • 0032941612 scopus 로고    scopus 로고
    • Attenuation of ischemia induced increases in sodium and calcium by the aldose reductase inhibitor zopolrestat
    • Ramasamy R., Liu H., Oates P.J., Schaefer S. Attenuation of ischemia induced increases in sodium and calcium by the aldose reductase inhibitor zopolrestat. Cardiovascular Research 1999, 42:130-139.
    • (1999) Cardiovascular Research , vol.42 , pp. 130-139
    • Ramasamy, R.1    Liu, H.2    Oates, P.J.3    Schaefer, S.4
  • 38
    • 0028920081 scopus 로고
    • Effects of glycogen depletion on ischemic injury in isolated rat hearts: insights into preconditioning
    • Schaefer S., Carr L.J., Prussel E., Ramasamy R. Effects of glycogen depletion on ischemic injury in isolated rat hearts: insights into preconditioning. The American Journal of Physiology 1995, 268:H935-H944.
    • (1995) The American Journal of Physiology , vol.268
    • Schaefer, S.1    Carr, L.J.2    Prussel, E.3    Ramasamy, R.4
  • 40
    • 0031036553 scopus 로고    scopus 로고
    • Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions
    • Stanley W.C., Lopaschuk G.D., Hall J.L., McCormack J.G. Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions. Cardiovascular Research 1997, 33:243-257.
    • (1997) Cardiovascular Research , vol.33 , pp. 243-257
    • Stanley, W.C.1    Lopaschuk, G.D.2    Hall, J.L.3    McCormack, J.G.4
  • 41
    • 0025162269 scopus 로고
    • Correlation between cytosolic free calcium, contracture, ATP, and irreversible ischemic injury in perfused rat heart
    • Steenbergen C., Murphy E., Watts J.A., London R.E. Correlation between cytosolic free calcium, contracture, ATP, and irreversible ischemic injury in perfused rat heart. Circulation Research 1990, 66:135-146.
    • (1990) Circulation Research , vol.66 , pp. 135-146
    • Steenbergen, C.1    Murphy, E.2    Watts, J.A.3    London, R.E.4
  • 43
    • 0032480276 scopus 로고    scopus 로고
    • Energy substrate metabolism, myocardial ischemia, and targets for pharmacotherapy
    • Taegtmeyer H., King L.M., Jones B.E. Energy substrate metabolism, myocardial ischemia, and targets for pharmacotherapy. The American Journal of Cardiology 1998, 82:54K-60K.
    • (1998) The American Journal of Cardiology , vol.82
    • Taegtmeyer, H.1    King, L.M.2    Jones, B.E.3
  • 44
    • 48449094505 scopus 로고    scopus 로고
    • Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart
    • Tang W.H., Wu S., Wong T.M., Chung S.K., Chung S.S. Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart. Free Radical Biology & Medicine 2008, 45:602-610.
    • (2008) Free Radical Biology & Medicine , vol.45 , pp. 602-610
    • Tang, W.H.1    Wu, S.2    Wong, T.M.3    Chung, S.K.4    Chung, S.S.5
  • 46
    • 33750868990 scopus 로고    scopus 로고
    • Aldose reductase inhibition improves altered glucose metabolism of isolated diabetic rat hearts
    • Trueblood N., Ramasamy R. Aldose reductase inhibition improves altered glucose metabolism of isolated diabetic rat hearts. The American Journal of Physiology 1998, 275:H75-H83.
    • (1998) The American Journal of Physiology , vol.275
    • Trueblood, N.1    Ramasamy, R.2
  • 47
    • 0028195091 scopus 로고
    • The relative importance of myocardial energy metabolism compared with ischemic contracture in the determination of ischemic injury in isolated perfused rabbit hearts
    • Vanoverschelde J.L., Janier M.F., Bergmann S.R. The relative importance of myocardial energy metabolism compared with ischemic contracture in the determination of ischemic injury in isolated perfused rabbit hearts. Circulation Research 1994, 74:817-828.
    • (1994) Circulation Research , vol.74 , pp. 817-828
    • Vanoverschelde, J.L.1    Janier, M.F.2    Bergmann, S.R.3
  • 49
  • 52
    • 0031028222 scopus 로고    scopus 로고
    • Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo
    • Young L.H., Renfu Y., Russell R., Hu X., Caplan M., Ren J., Shulman G.I., Sinusas A.J. Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo. Circulation 1997, 95:415-422.
    • (1997) Circulation , vol.95 , pp. 415-422
    • Young, L.H.1    Renfu, Y.2    Russell, R.3    Hu, X.4    Caplan, M.5    Ren, J.6    Shulman, G.I.7    Sinusas, A.J.8


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