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Volumn , Issue , 2008, Pages 84-98

Molecular Biology of Preneoplastic Lesions of the Lung

Author keywords

Lung cancer; Molecular biology; Preneoplastic lesions; Squamous cell carcinoma

Indexed keywords


EID: 79960599272     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470696330.ch5     Document Type: Chapter
Times cited : (1)

References (102)
  • 3
    • 29244484904 scopus 로고    scopus 로고
    • Tumours of the lung
    • In: Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC (eds). Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer (IARC)
    • Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC. Tumours of the lung. In: Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC (eds). Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer (IARC), 2004:9-124.
    • (2004) , pp. 9-124
    • Travis, W.D.1    Brambilla, E.2    Muller-Hermelink, H.K.3    Harris, C.C.4
  • 5
    • 0035065024 scopus 로고    scopus 로고
    • Pulmonary preinvasive neoplasia
    • Kerr KM. Pulmonary preinvasive neoplasia. J Clin Pathol 2001; 54:257-71.
    • (2001) J Clin Pathol , vol.54 , pp. 257-271
    • Kerr, K.M.1
  • 6
    • 34547444790 scopus 로고    scopus 로고
    • Squamous dysplasia and carcinoma in situ
    • In: Travis W, Brambilla E, Muller-Hermelink HK, Harris CC (eds). Pathology and Genetics Tumors of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer (IARC)
    • Franklin W, Wistuba I, Geisinger K et al. Squamous dysplasia and carcinoma in situ. In: Travis W, Brambilla E, Muller-Hermelink HK, Harris CC (eds). Pathology and Genetics Tumors of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer (IARC), 2004:68-72.
    • (2004) , pp. 68-72
    • Franklin, W.1    Wistuba, I.2    Geisinger, K.3
  • 7
    • 0033590626 scopus 로고    scopus 로고
    • Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
    • Wistuba II, Behrens C, Milchgrub S et al. Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma. Oncogene 1999; 18:643-50.
    • (1999) Oncogene , vol.18 , pp. 643-650
    • Wistuba, I.I.1    Behrens, C.2    Milchgrub, S.3
  • 8
    • 0033927099 scopus 로고    scopus 로고
    • Molecular changes in the bronchial epithelium of patients with small cell lung cancer
    • Wistuba II, Berry J, Behrens C et al. Molecular changes in the bronchial epithelium of patients with small cell lung cancer. Clin Cancer Res 2000; 6:2604-10.
    • (2000) Clin Cancer Res , vol.6 , pp. 2604-2610
    • Wistuba, I.I.1    Berry, J.2    Behrens, C.3
  • 9
    • 19244370711 scopus 로고    scopus 로고
    • High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints
    • Wistuba II, Behrens C, Virmani AK et al. High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 2000; 60(7):1949-60.
    • (2000) Cancer Res , vol.60 , Issue.7 , pp. 1949-1960
    • Wistuba, I.I.1    Behrens, C.2    Virmani, A.K.3
  • 10
    • 0037152658 scopus 로고    scopus 로고
    • Smoking molecular damage in bronchial epitheliu
    • Oct 21
    • Wistuba II, Mao L, Gazdar AF. Smoking molecular damage in bronchial epitheliu. Oncogene Oct 21, 2002; 21(48):7298-306.
    • (2002) Oncogene , vol.21 , Issue.48 , pp. 7298-7306
    • Wistuba, I.I.1    Mao, L.2    Gazdar, A.F.3
  • 11
    • 0030846720 scopus 로고    scopus 로고
    • Molecular damage in the bronchial epithelium of current and former smokers
    • Wistuba II, Lam S, Behrens C et al. Molecular damage in the bronchial epithelium of current and former smokers. J Natl Cancer Inst 1997; 89:1366-73.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1366-1373
    • Wistuba, I.I.1    Lam, S.2    Behrens, C.3
  • 12
    • 1842298166 scopus 로고    scopus 로고
    • Clonal genetic alterations in the lungs of current and former smokers
    • Mao L, Lee JS, Kurie JM et al. Clonal genetic alterations in the lungs of current and former smokers. J Natl Cancer Inst 1997; 89:857-62.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 857-862
    • Mao, L.1    Lee, J.S.2    Kurie, J.M.3
  • 13
    • 33644854732 scopus 로고    scopus 로고
    • Current issues in lung cancer screening
    • Nov, discussion
    • Mulshine JL. Current issues in lung cancer screening. Oncology (Williston Park) Nov 2005; 19(13):1724-30; discussion 30-1.
    • (2005) Oncology (Williston Park) , vol.19 , Issue.13
    • Mulshine, J.L.1
  • 14
    • 0034548754 scopus 로고    scopus 로고
    • Detection and localization of early lung cancer by fluorescence bronchoscopy
    • Cancer Dec 1
    • Lam S, MacAulay C, leRiche JC, Palcic B. Detection and localization of early lung cancer by fluorescence bronchoscopy. Cancer Dec 1, 2000; 89(Suppl 11): 2468-73.
    • (2000) , vol.89 , Issue.SUPPL. 11 , pp. 2468-2473
    • Lam, S.1    MacAulay, C.2    leRiche, J.C.3    Palcic, B.4
  • 15
    • 0037890342 scopus 로고    scopus 로고
    • Early glandular neoplasia of the lung
    • Westra WH. Early glandular neoplasia of the lung. Respir Med 2000; 1:163-9.
    • (2000) Respir Med , vol.1 , pp. 163-169
    • Westra, W.H.1
  • 16
    • 0034026352 scopus 로고    scopus 로고
    • Angiogenic squamous dysplasia in bronchi of individuals at high risk for lung cancer
    • Keith RL, Miller YE, Gemmill RM et al. Angiogenic squamous dysplasia in bronchi of individuals at high risk for lung cancer. Clin Cancer Res 2000; 6(5):1616-25.
    • (2000) Clin Cancer Res , vol.6 , Issue.5 , pp. 1616-1625
    • Keith, R.L.1    Miller, Y.E.2    Gemmill, R.M.3
  • 17
    • 33744900918 scopus 로고    scopus 로고
    • A clinicopathological study of resected pulmonary nodules with focal pure ground-glass opacity
    • Ohtsuka T, Watanabe K, Kaji M, Naruke T, Suemasu K. A clinicopathological study of resected pulmonary nodules with focal pure ground-glass opacity. Eur J Cardiothorac Surg Jul 2006; 30(1):160-3.
    • (2006) Eur J Cardiothorac Surg Jul , vol.30 , Issue.1 , pp. 160-163
    • Ohtsuka, T.1    Watanabe, K.2    Kaji, M.3    Naruke, T.4    Suemasu, K.5
  • 18
    • 0032949035 scopus 로고    scopus 로고
    • Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma [see comments]
    • Kitamura H, Kameda Y, Ito T, Hayashi H. Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma [see comments]. Am J Clin Pathol 1999; 111(5):610-22.
    • (1999) Am J Clin Pathol , vol.111 , Issue.5 , pp. 610-622
    • Kitamura, H.1    Kameda, Y.2    Ito, T.3    Hayashi, H.4
  • 19
    • 0035195449 scopus 로고    scopus 로고
    • Unique cellular features in atypical adenomatous hyperplasia of the lung: ultrastructural evidence of its cytodifferentiation
    • Osanai M, Igarashi T, Yoshida Y. Unique cellular features in atypical adenomatous hyperplasia of the lung: ultrastructural evidence of its cytodifferentiation. Ultrastruct Pathol 2001; 25:367-73.
    • (2001) Ultrastruct Pathol , vol.25 , pp. 367-373
    • Osanai, M.1    Igarashi, T.2    Yoshida, Y.3
  • 20
    • 0025247838 scopus 로고
    • Alveolar epithelial hyperplasia and adenocarcinoma of the lung
    • Nakanishi K. Alveolar epithelial hyperplasia and adenocarcinoma of the lung. Arch Pathol Lab Med 1990; 114(4):363-8.
    • (1990) Arch Pathol Lab Med , vol.114 , Issue.4 , pp. 363-368
    • Nakanishi, K.1
  • 21
    • 0033889875 scopus 로고    scopus 로고
    • The association between atypical adenomatous hyperplasia and primary lung cancer
    • Chapman AD, Kerr KM. The association between atypical adenomatous hyperplasia and primary lung cancer. Br J Cancer 2000; 83:632-6.
    • (2000) Br J Cancer , vol.83 , pp. 632-636
    • Chapman, A.D.1    Kerr, K.M.2
  • 22
    • 18344383148 scopus 로고    scopus 로고
    • Lung adenocarcinoma with bronchioloalveolar carcinoma component is frequently associated with foci of high-grade atypical adenomatous hyperplasia
    • Koga T, Hashimoto S, Sugio K et al. Lung adenocarcinoma with bronchioloalveolar carcinoma component is frequently associated with foci of high-grade atypical adenomatous hyperplasia. Am J Clin Pathol 2002; 117:464-70.
    • (2002) Am J Clin Pathol , vol.117 , pp. 464-470
    • Koga, T.1    Hashimoto, S.2    Sugio, K.3
  • 23
    • 0034904828 scopus 로고    scopus 로고
    • Atypical adenomatous hyperplasia of the lung in autopsy cases
    • Yokose T, Doi M, Tanno K, Yamazaki K, Ochiai A. Atypical adenomatous hyperplasia of the lung in autopsy cases. Lung Cancer 2001; 33:155-61.
    • (2001) Lung Cancer , vol.33 , pp. 155-161
    • Yokose, T.1    Doi, M.2    Tanno, K.3    Yamazaki, K.4    Ochiai, A.5
  • 24
    • 0029079864 scopus 로고
    • Diffuse idiopathic pulmonary neuroendocrine cell proliferation presenting as interstitial lung disease
    • Armas OA, White DA, Erlanson RA, Rosai J. Diffuse idiopathic pulmonary neuroendocrine cell proliferation presenting as interstitial lung disease. Am J Surg Pathol 1995; 19:963-70.
    • (1995) Am J Surg Pathol , vol.19 , pp. 963-970
    • Armas, O.A.1    White, D.A.2    Erlanson, R.A.3    Rosai, J.4
  • 25
    • 4644274700 scopus 로고    scopus 로고
    • Mutations and addiction to EGFR: the Achilles "heal" of lung cancers?
    • Oct
    • Gazdar AF, Shigematsu H, Herz J, Minna JD. Mutations and addiction to EGFR: the Achilles "heal" of lung cancers? Trends Mol Med Oct 2004; 10(10):481-6.
    • (2004) Trends Mol Med , vol.10 , Issue.10 , pp. 481-486
    • Gazdar, A.F.1    Shigematsu, H.2    Herz, J.3    Minna, J.D.4
  • 26
    • 24744461722 scopus 로고    scopus 로고
    • EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patient
    • Sep 1
    • Tang X, Shigematsu H, Bekele BN et al. EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patient. Cancer Res Sep 1, 2005; 65(17):7568-72.
    • (2005) Cancer Res , vol.65 , Issue.17 , pp. 7568-7572
    • Tang, X.1    Shigematsu, H.2    Bekele, B.N.3
  • 27
    • 0033561528 scopus 로고    scopus 로고
    • Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer
    • Wistuba II, Behrens C, Virmani AK et al. Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer. Cancer Res 1999; 59(8):1973-9.
    • (1999) Cancer Res , vol.59 , Issue.8 , pp. 1973-1979
    • Wistuba, I.I.1    Behrens, C.2    Virmani, A.K.3
  • 28
    • 0031905596 scopus 로고    scopus 로고
    • Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma
    • Yashima K, Milchgrub S, Gollahon LS et al. Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma. Clin Cancer Res 1998; 4(1):229-34.
    • (1998) Clin Cancer Res , vol.4 , Issue.1 , pp. 229-234
    • Yashima, K.1    Milchgrub, S.2    Gollahon, L.S.3
  • 29
    • 27544487984 scopus 로고    scopus 로고
    • Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cance
    • Nov 1
    • Miyazu YM, Miyazawa T, Hiyama K et al. Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cance. Cancer Res Nov 1, 2005; 65(21):9623-7.
    • (2005) Cancer Res , vol.65 , Issue.21 , pp. 9623-9627
    • Miyazu, Y.M.1    Miyazawa, T.2    Hiyama, K.3
  • 30
    • 16344370724 scopus 로고    scopus 로고
    • Telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesion
    • Mar 1
    • Lantuejoul S, Soria JC, Morat L et al. Telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesion. Clin Cancer Res Mar 1, 2005; 11(5):2074-82.
    • (2005) Clin Cancer Res , vol.11 , Issue.5 , pp. 2074-2082
    • Lantuejoul, S.1    Soria, J.C.2    Morat, L.3
  • 31
    • 0033520789 scopus 로고    scopus 로고
    • Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer [in process citation]
    • Park IW, Wistuba II, Maitra A et al. Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer [in process citation]. J Natl Cancer Inst 1999; 91(21):1863-8.
    • (1999) J Natl Cancer Inst , vol.91 , Issue.21 , pp. 1863-1868
    • Park, I.W.1    Wistuba, I.I.2    Maitra, A.3
  • 32
    • 0035324425 scopus 로고    scopus 로고
    • 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer
    • Zochbauer-Muller S, Fong KM, Maitra A et al. 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer. Cancer Res 2001; 61(9):3581-5.
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3581-3585
    • Zochbauer-Muller, S.1    Fong, K.M.2    Maitra, A.3
  • 33
    • 0142053910 scopus 로고    scopus 로고
    • Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smoker
    • Nov 20
    • Zochbauer-Muller S, Lam S, Toyooka S et al. Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smoker. Int J Cancer Nov 20, 2003; 107(4):612-6.
    • (2003) Int J Cancer , vol.107 , Issue.4 , pp. 612-616
    • Zochbauer-Muller, S.1    Lam, S.2    Toyooka, S.3
  • 34
    • 0037081176 scopus 로고    scopus 로고
    • Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smoker
    • Jan 15
    • Soria JC, Rodriguez M, Liu DD, Lee JJ, Hong WK, Mao L. Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smoker. Cancer Res Jan 15, 2002; 62(2):351-5.
    • (2002) Cancer Res , vol.62 , Issue.2 , pp. 351-355
    • Soria, J.C.1    Rodriguez, M.2    Liu, D.D.3    Lee, J.J.4    Hong, W.K.5    Mao, L.6
  • 35
    • 0032578509 scopus 로고    scopus 로고
    • Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
    • Belinsky SA, Nikula KJ, PalmisanoWA et al. Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci U S A 1998; 95(20):11891-6.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.20 , pp. 11891-11896
    • Belinsky, S.A.1    Nikula, K.J.2    Palmisano, W.A.3
  • 36
    • 0037089460 scopus 로고    scopus 로고
    • Aberrant promoter methylation in bronchial epithelium and sputum from current and former smoker
    • Apr 15
    • Belinsky SA, Palmisano WA, Gilliland FD et al. Aberrant promoter methylation in bronchial epithelium and sputum from current and former smoker. Cancer Res Apr 15, 2002; 62(8):2370-7.
    • (2002) Cancer Res , vol.62 , Issue.8 , pp. 2370-2377
    • Belinsky, S.A.1    Palmisano, W.A.2    Gilliland, F.D.3
  • 37
    • 33645521023 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohor
    • Mar 15
    • Belinsky SA, Liechty KC, Gentry FD et al. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohor. Cancer Res Mar 15, 2006; 66(6):3338-44.
    • (2006) Cancer Res , vol.66 , Issue.6 , pp. 3338-3344
    • Belinsky, S.A.1    Liechty, K.C.2    Gentry, F.D.3
  • 38
    • 32944468706 scopus 로고    scopus 로고
    • Mutational and epigenetic evidence for independent pathways for lung adenocarcinomas arising in smokers and never smoker
    • Feb 1
    • Toyooka S, Tokumo M, ShigematsuHet al. Mutational and epigenetic evidence for independent pathways for lung adenocarcinomas arising in smokers and never smoker. Cancer Res Feb 1, 2006; 66(3):1371-5.
    • (2006) Cancer Res , vol.66 , Issue.3 , pp. 1371-1375
    • Toyooka, S.1    Tokumo, M.2    Shigematsu, H.3
  • 39
    • 0034327412 scopus 로고    scopus 로고
    • The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor gene. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium
    • Lerman MI, Minna JD. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor gene. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium. Cancer Res 2000; 60(21):6116-33.
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 6116-6133
    • Lerman, M.I.1    Minna, J.D.2
  • 40
    • 0037037787 scopus 로고    scopus 로고
    • Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancer
    • Oct 7
    • Zabarovsky ER, Lerman MI, Minna JD. Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancer. Oncogene Oct 7, 2002; 21(45):6915-35.
    • (2002) Oncogene , vol.21 , Issue.45 , pp. 6915-6935
    • Zabarovsky, E.R.1    Lerman, M.I.2    Minna, J.D.3
  • 41
    • 30444435605 scopus 로고    scopus 로고
    • Proteomic patterns of preinvasive bronchial lesion
    • Dec 15
    • Rahman SM, Shyr Y, Yildiz PB et al. Proteomic patterns of preinvasive bronchial lesion. Am J Respir Crit Care Med Dec 15, 2005; 172(12):1556-62.
    • (2005) Am J Respir Crit Care Med , vol.172 , Issue.12 , pp. 1556-1562
    • Rahman, S.M.1    Shyr, Y.2    Yildiz, P.B.3
  • 42
    • 13944255788 scopus 로고    scopus 로고
    • Global gene expression analysis of human bronchial epithelial cells treated with tobacco condensates
    • Jorgensen ED, Dozmorov I, Frank MB, Centola M, Albino AP. Global gene expression analysis of human bronchial epithelial cells treated with tobacco condensates. Cell Cycle Sep 2004; 3(9):1154-68.
    • (2004) Cell Cycle Sep , vol.3 , Issue.9 , pp. 1154-1168
    • Jorgensen, E.D.1    Dozmorov, I.2    Frank, M.B.3    Centola, M.4    Albino, A.P.5
  • 43
    • 0035135235 scopus 로고    scopus 로고
    • Early detection of lung cancer: clinical perspectives of recent advances in biology and radiology
    • Hirsch FR, Franklin WA, Gazdar AF, Bunn PA, Jr. Early detection of lung cancer: clinical perspectives of recent advances in biology and radiology. Clin Cancer Res Jan 2001; 7(1):5-22.
    • (2001) Clin Cancer Res Jan , vol.7 , Issue.1 , pp. 5-22
    • Hirsch, F.R.1    Franklin, W.A.2    Gazdar, A.F.3    Bunn Jr, P.A.4
  • 44
    • 0035913614 scopus 로고    scopus 로고
    • Fluorescence versus white-light bronchoscopy for detection of preneoplastic lesions: a randomized stud
    • Sep 19
    • Hirsch FR, Prindiville SA, Miller YE et al. Fluorescence versus white-light bronchoscopy for detection of preneoplastic lesions: a randomized stud. J Natl Cancer Inst Sep 19, 2001; 93(18):1385-91.
    • (2001) J Natl Cancer Inst , vol.93 , Issue.18 , pp. 1385-1391
    • Hirsch, F.R.1    Prindiville, S.A.2    Miller, Y.E.3
  • 45
    • 15044347694 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor and its receptors in bronchial dysplasia demonstrated by quantitative RT-PCR analysis
    • Merrick DT, Haney J, Petrunich S et al. Overexpression of vascular endothelial growth factor and its receptors in bronchial dysplasia demonstrated by quantitative RT-PCR analysis. Lung Cancer Apr 2005; 48(1):31-45.
    • (2005) Lung Cancer Apr , vol.48 , Issue.1 , pp. 31-45
    • Merrick, D.T.1    Haney, J.2    Petrunich, S.3
  • 46
    • 33646848944 scopus 로고    scopus 로고
    • From the bench to the bed: individualizing treatment in non-small-cell lung cancer
    • Santarpia M, Altavilla G, Salazar F, Taron M, Rosell R. From the bench to the bed: individualizing treatment in non-small-cell lung cancer. Clin Transl Oncol Feb 2006; 8(2):71-6.
    • (2006) Clin Transl Oncol Feb , vol.8 , Issue.2 , pp. 71-76
    • Santarpia, M.1    Altavilla, G.2    Salazar, F.3    Taron, M.4    Rosell, R.5
  • 47
    • 5444275938 scopus 로고    scopus 로고
    • The convergence of cancer prevention and therapy in early-phase clinical drug development
    • Abbruzzese JL, Lippman SM. The convergence of cancer prevention and therapy in early-phase clinical drug development. Cancer Cell Oct 2004; 6(4):321-6.
    • (2004) Cancer Cell Oct , vol.6 , Issue.4 , pp. 321-326
    • Abbruzzese, J.L.1    Lippman, S.M.2
  • 48
    • 19844371226 scopus 로고    scopus 로고
    • Advances in the biology of lung cancer chemopreventio
    • May 10
    • Hirsch FR, Lippman SM. Advances in the biology of lung cancer chemopreventio. J Clin Oncol May 10, 2005; 23(14):3186-97.
    • (2005) J Clin Oncol , vol.23 , Issue.14 , pp. 3186-3197
    • Hirsch, F.R.1    Lippman, S.M.2
  • 49
    • 3042668237 scopus 로고    scopus 로고
    • Molecularly targeted approaches to the chemoprevention of lung cancer
    • Jun 15
    • Khuri FR, Cohen V. Molecularly targeted approaches to the chemoprevention of lung cancer. Clin Cancer Res Jun 15, 2004; 10(12, Pt 2):4249s-53s.
    • (2004) Clin Cancer Res , vol.10 , Issue.12 PT. 2
    • Khuri, F.R.1    Cohen, V.2
  • 50
    • 20244367301 scopus 로고    scopus 로고
    • Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ra
    • Apr 15
    • Wislez M, Spencer ML, Izzo JG et al. Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ra. Cancer Res Apr 15, 2005; 65(8):3226-35.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3226-3235
    • Wislez, M.1    Spencer, M.L.2    Izzo, J.G.3
  • 51
    • 33646255924 scopus 로고    scopus 로고
    • High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic KRA
    • Apr 15
    • Wislez M, Fujimoto N, Izzo JG et al. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic KRA. Cancer Res Apr 15, 2006; 66(8):4198-207.
    • (2006) Cancer Res , vol.66 , Issue.8 , pp. 4198-4207
    • Wislez, M.1    Fujimoto, N.2    Izzo, J.G.3
  • 52
    • 33646272201 scopus 로고    scopus 로고
    • Analysis of c-ErbB1/epidermal growth factor receptor and c-ErbB2/HER-2 expression in bronchial dysplasia: evaluation of potential targets for chemoprevention of lung cancer
    • Apr 1
    • Merrick DT, Kittelson J,Winterhalder R et al. Analysis of c-ErbB1/epidermal growth factor receptor and c-ErbB2/HER-2 expression in bronchial dysplasia: evaluation of potential targets for chemoprevention of lung cancer. Clin Cancer Res Apr 1, 2006; 12(7, Pt 1):2281-8.
    • (2006) Clin Cancer Res , vol.12 , Issue.7 PT. 1 , pp. 2281-2288
    • Merrick, D.T.1    Kittelson, J.2    Winterhalder, R.3
  • 53
    • 0041846604 scopus 로고    scopus 로고
    • Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studies
    • Tsao AS, McDonnell T, Lam S et al. Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studies. Cancer Epidemiol Biomarkers Prev Jul 2003; 12(7):660-4.
    • (2003) Cancer Epidemiol Biomarkers Prev Jul , vol.12 , Issue.7 , pp. 660-664
    • Tsao, A.S.1    McDonnell, T.2    Lam, S.3
  • 54
    • 27944452718 scopus 로고    scopus 로고
    • Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesi
    • Nov 16
    • Lee HY, Oh SH,Woo JK et al. Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesi. J Natl Cancer Inst Nov 16, 2005; 97(22):1695-9.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.22 , pp. 1695-1699
    • Lee, H.Y.1    Oh, S.H.2    Woo, J.K.3
  • 55
    • 6944229580 scopus 로고    scopus 로고
    • Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cell
    • Oct 20
    • Lee HY, Moon H, Chun KH et al. Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cell. J Natl Cancer Inst Oct 20, 2004; 96(20):1536-48.
    • (2004) J Natl Cancer Inst , vol.96 , Issue.20 , pp. 1536-1548
    • Lee, H.Y.1    Moon, H.2    Chun, K.H.3
  • 56
    • 0029933372 scopus 로고    scopus 로고
    • K-ras oncogene activation in atypical alveolar hyperplasias of the human lung
    • Westra WH, Baas IO, Hruban RH et al. K-ras oncogene activation in atypical alveolar hyperplasias of the human lung. Cancer Res 1996; 56:2224-8.
    • (1996) Cancer Res , vol.56 , pp. 2224-2228
    • Westra, W.H.1    Baas, I.O.2    Hruban, R.H.3
  • 57
    • 12244269936 scopus 로고    scopus 로고
    • Detection and discrimination of preneoplastic and early stages of lung adenocarcinoma using hmRNP B1, combined with the cell cycle-related markers p16, cyclin D1, and Ki-67
    • Tominaga M, Sueoka N, Irie K et al. Detection and discrimination of preneoplastic and early stages of lung adenocarcinoma using hmRNP B1, combined with the cell cycle-related markers p16, cyclin D1, and Ki-67. Lung Cancer 2003; 40:45-53.
    • (2003) Lung Cancer , vol.40 , pp. 45-53
    • Tominaga, M.1    Sueoka, N.2    Irie, K.3
  • 59
    • 0032019233 scopus 로고    scopus 로고
    • Proliferative activity, p53 expressin and loss of heterozygosity on 3p, 9 and 17p in atypical adenomatous hyperplasia of the lung
    • Kitaguchi S, Takeshima Y, Nishisaka T, Inai K. Proliferative activity, p53 expressin and loss of heterozygosity on 3p, 9 and 17p in atypical adenomatous hyperplasia of the lung. Hiroshima J Med Sci 1998; 47:17-25.
    • (1998) Hiroshima J Med Sci , vol.47 , pp. 17-25
    • Kitaguchi, S.1    Takeshima, Y.2    Nishisaka, T.3    Inai, K.4
  • 60
    • 0035149254 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 9q and 16p in atypical adenomatous hyperplasia concomitant with adenocarcinoma of the lung
    • Takamochi K, Ogura T, Suzuki K et al. Loss of heterozygosity on chromosome 9q and 16p in atypical adenomatous hyperplasia concomitant with adenocarcinoma of the lung. Am J Pathol 2001; 159:1941-8.
    • (2001) Am J Pathol , vol.159 , pp. 1941-1948
    • Takamochi, K.1    Ogura, T.2    Suzuki, K.3
  • 61
    • 0036651125 scopus 로고    scopus 로고
    • Expression of human telomerase RNA component and telomerase reverse transcriptase mRNA in atypical adenomatous hyperplasia of the lung
    • Nakanishi K, Kawai T, Kumaki F, Hirot S, Mukai M, Ikeda E. Expression of human telomerase RNA component and telomerase reverse transcriptase mRNA in atypical adenomatous hyperplasia of the lung. Hum Pathol 2002; 33:697-702.
    • (2002) Hum Pathol , vol.33 , pp. 697-702
    • Nakanishi, K.1    Kawai, T.2    Kumaki, F.3    Hirot, S.4    Mukai, M.5    Ikeda, E.6
  • 62
    • 0042525904 scopus 로고    scopus 로고
    • LKB1 protein expression in the evolution of glandular neoplasia of the lung
    • Ghaffar H, Sahin F, Sanchez-Cespedes M et al. LKB1 protein expression in the evolution of glandular neoplasia of the lung. Clin Cancer Res 2003; 9:2998-3003.
    • (2003) Clin Cancer Res , vol.9 , pp. 2998-3003
    • Ghaffar, H.1    Sahin, F.2    Sanchez-Cespedes, M.3
  • 63
    • 11144355464 scopus 로고    scopus 로고
    • Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortiu
    • Apr 1
    • Nikitin AY, Alcaraz A, Anver MR et al. Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortiu. Cancer Res Apr 1, 2004; 64(7):2307-16.
    • (2004) Cancer Res , vol.64 , Issue.7 , pp. 2307-2316
    • Nikitin, A.Y.1    Alcaraz, A.2    Anver, M.R.3
  • 64
    • 20444397431 scopus 로고    scopus 로고
    • Identification of bronchioalveolar stem cells in normal lung and lung cance
    • Jun 17
    • Kim CF, Jackson EL, Woolfenden AE et al. Identification of bronchioalveolar stem cells in normal lung and lung cance. Cell Jun 17, 2005; 121(6):823-35.
    • (2005) Cell , vol.121 , Issue.6 , pp. 823-835
    • Kim, C.F.1    Jackson, E.L.2    Woolfenden, A.E.3
  • 65
    • 23244447893 scopus 로고    scopus 로고
    • Tumour biology: senescence in premalignant tumour
    • Aug 4
    • Collado M, Gil J, Efeyan A et al. Tumour biology: senescence in premalignant tumour. Nature Aug 4, 2005; 436(7051):642.
    • (2005) Nature , vol.436 , Issue.7051 , pp. 642
    • Collado, M.1    Gil, J.2    Efeyan, A.3
  • 66
    • 72849170034 scopus 로고
    • Changes in bronchial epithelium in relation to smoking and cancer of the lung
    • Auerbach O, Stout AP, Hammond EC, Garfinkel L. Changes in bronchial epithelium in relation to smoking and cancer of the lung. N Engl J Med 1961; 265:253-67.
    • (1961) N Engl J Med , vol.265 , pp. 253-267
    • Auerbach, O.1    Stout, A.P.2    Hammond, E.C.3    Garfinkel, L.4
  • 67
    • 78651056338 scopus 로고
    • "Field cancerization" in oral stratified squamous epithelium: clinical implications of multicentric origin
    • Slaughter DP, Southwick HW, SmejkalW. "Field cancerization" in oral stratified squamous epithelium: clinical implications of multicentric origin. Cancer 1954; 6(963):963-8.
    • (1954) Cancer , vol.6 , Issue.963 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 68
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cance
    • Dec 19-26
    • Coussens LM, Werb Z. Inflammation and cance. Nature Dec 19-26, 2002; 420(6917):860-7.
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 69
    • 0042565930 scopus 로고    scopus 로고
    • The potential contributions of chronic inflammation to lung carcinogenesis
    • Ballaz S, Mulshine JL. The potential contributions of chronic inflammation to lung carcinogenesis. Clin Lung Cancer Jul 2003; 5(1):46-62.
    • (2003) Clin Lung Cancer Jul , vol.5 , Issue.1 , pp. 46-62
    • Ballaz, S.1    Mulshine, J.L.2
  • 70
    • 0037304945 scopus 로고    scopus 로고
    • Acquired somatic mutations in the molecular pathogenesis of COPD
    • Anderson GP, Bozinovski S. Acquired somatic mutations in the molecular pathogenesis of COPD. Trends Pharmacol Sci Feb 2003; 24(2):71-6.
    • (2003) Trends Pharmacol Sci Feb , vol.24 , Issue.2 , pp. 71-76
    • Anderson, G.P.1    Bozinovski, S.2
  • 71
    • 4344675455 scopus 로고    scopus 로고
    • Pathophysiology of airflow limitation in chronic obstructive pulmonary diseas
    • Aug 21-27
    • Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary diseas. Lancet Aug 21-27, 2004; 364(9435):709-21.
    • (2004) Lancet , vol.364 , Issue.9435 , pp. 709-721
    • Hogg, J.C.1
  • 72
    • 0034721232 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary diseas
    • Jul 27
    • Barnes PJ. Chronic obstructive pulmonary diseas. N Engl J Med Jul 27, 2000; 343(4):269-80.
    • (2000) N Engl J Med , vol.343 , Issue.4 , pp. 269-280
    • Barnes, P.J.1
  • 73
    • 0034026144 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines
    • Hida T, Kozaki K, MuramatsuHet al. Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines. Clin Cancer Res May 2000; 6(5):2006-11.
    • (2000) Clin Cancer Res May , vol.6 , Issue.5 , pp. 2006-2011
    • Hida, T.1    Kozaki, K.2    Muramatsu, H.3
  • 74
    • 10144261885 scopus 로고    scopus 로고
    • Cytopathological analysis of sputum in patients with airflow obstruction and significant smoking histories
    • Kennedy TC, Proudfoot SP, Franklin WA et al. Cytopathological analysis of sputum in patients with airflow obstruction and significant smoking histories. Cancer Res 1996; 56(20):4673-8.
    • (1996) Cancer Res , vol.56 , Issue.20 , pp. 4673-4678
    • Kennedy, T.C.1    Proudfoot, S.P.2    Franklin, W.A.3
  • 75
    • 0033590963 scopus 로고    scopus 로고
    • Sex-related differences in bronchial epithelial changes associated with tobacco smoking
    • Lam S, LeRiche JC, Zheng Y et al. Sex-related differences in bronchial epithelial changes associated with tobacco smoking. J Natl Cancer Inst 1999; 91(8):691-6.
    • (1999) J Natl Cancer Inst , vol.91 , Issue.8 , pp. 691-696
    • Lam, S.1    LeRiche, J.C.2    Zheng, Y.3
  • 76
    • 21344464734 scopus 로고    scopus 로고
    • Tobacco components stimulate Akt-dependent proliferation and NFκB-dependent survival in lung cancer cells
    • Tsurutani J, Castillo SS, Brognard J et al. Tobacco components stimulate Akt-dependent proliferation and NFκB-dependent survival in lung cancer cells. Carcinogenesis Jul 2005; 26(7):1182-95.
    • (2005) Carcinogenesis Jul , vol.26 , Issue.7 , pp. 1182-1195
    • Tsurutani, J.1    Castillo, S.S.2    Brognard, J.3
  • 77
    • 33751570051 scopus 로고    scopus 로고
    • Nuclear factor-kB (NFkB) is frequently activated in lung cancer and preneoplastic lesion
    • Dec 1
    • Tang X, Liu D, Shishodia S et al. Nuclear factor-kB (NFkB) is frequently activated in lung cancer and preneoplastic lesion. Cancer Dec 1, 2006; 107(11):2637-46.
    • (2006) Cancer , vol.107 , Issue.11 , pp. 2637-2646
    • Tang, X.1    Liu, D.2    Shishodia, S.3
  • 78
    • 29244445792 scopus 로고    scopus 로고
    • Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies
    • Tichelaar JW, Zhang Y, LeRiche JC, Biddinger PW, Lam S, Anderson MW. Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies. BMC Cancer 2005; 5:155.
    • (2005) BMC Cancer , vol.5 , pp. 155
    • Tichelaar, J.W.1    Zhang, Y.2    LeRiche, J.C.3    Biddinger, P.W.4    Lam, S.5    Anderson, M.W.6
  • 79
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: the enemy within
    • Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell Sep 2004; 6(3):203-8.
    • (2004) Cancer Cell Sep , vol.6 , Issue.3 , pp. 203-208
    • Aggarwal, B.B.1
  • 80
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: linking inflammation and immunity to cancer development and progression
    • Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol Oct 2005; 5(10):749-59.
    • (2005) Nat Rev Immunol Oct , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 81
    • 4644324186 scopus 로고    scopus 로고
    • NF-kappaB functions as a tumour promoter in inflammation-associated cance
    • Sep 23
    • Pikarsky E, Porat RM, Stein I et al. NF-kappaB functions as a tumour promoter in inflammation-associated cance. Nature Sep 23, 2004; 431(7007):461-6.
    • (2004) Nature , vol.431 , Issue.7007 , pp. 461-466
    • Pikarsky, E.1    Porat, R.M.2    Stein, I.3
  • 82
    • 3843052483 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: its role in health and disease
    • Kumar A, Takada Y, Boriek AM, Aggarwal BB. Nuclear factor-kappaB: its role in health and disease. J Mol Med Jul 2004; 82(7):434-48.
    • (2004) J Mol Med Jul , vol.82 , Issue.7 , pp. 434-448
    • Kumar, A.1    Takada, Y.2    Boriek, A.M.3    Aggarwal, B.B.4
  • 83
    • 4143134494 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: a friend or a foe in cancer?
    • Sep 15
    • Shishodia S, Aggarwal BB. Nuclear factor-kappaB: a friend or a foe in cancer? Biochem Pharmacol Sep 15, 2004; 68(6):1071-80.
    • (2004) Biochem Pharmacol , vol.68 , Issue.6 , pp. 1071-1080
    • Shishodia, S.1    Aggarwal, B.B.2
  • 84
    • 0035468642 scopus 로고    scopus 로고
    • Cyclooxygenase 2: a pharmacological target for the prevention of cancer
    • Dannenberg AJ, Altorki NK, Boyle JO et al. Cyclooxygenase 2: a pharmacological target for the prevention of cancer. Lancet Oncol Sep 2001; 2(9):544-51.
    • (2001) Lancet Oncol Sep , vol.2 , Issue.9 , pp. 544-551
    • Dannenberg, A.J.1    Altorki, N.K.2    Boyle, J.O.3
  • 85
    • 0037083634 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-1 and cyclooxygenase-2 in bronchial epithelium and nonsmall cell lung carcinom
    • Feb 15
    • Hasturk S, Kemp B, Kalapurakal SK, Kurie JM, Hong WK, Lee JS. Expression of cyclooxygenase-1 and cyclooxygenase-2 in bronchial epithelium and nonsmall cell lung carcinom. Cancer Feb 15, 2002; 94(4):1023-31.
    • (2002) Cancer , vol.94 , Issue.4 , pp. 1023-1031
    • Hasturk, S.1    Kemp, B.2    Kalapurakal, S.K.3    Kurie, J.M.4    Hong, W.K.5    Lee, J.S.6
  • 86
    • 23844461887 scopus 로고    scopus 로고
    • Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer
    • Mao JT, Cui X, Reckamp K et al. Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer. Clin Lung Cancer Jul 2005; 7(1):30-9.
    • (2005) Clin Lung Cancer Jul , vol.7 , Issue.1 , pp. 30-39
    • Mao, J.T.1    Cui, X.2    Reckamp, K.3
  • 88
    • 31544467105 scopus 로고    scopus 로고
    • Celecoxib decreases Ki-67 proliferative index in active smoker
    • Jan 1
    • Mao JT, Fishbein MC, Adams B et al. Celecoxib decreases Ki-67 proliferative index in active smoker. Clin Cancer Res Jan 1, 2006; 12(1):314-20.
    • (2006) Clin Cancer Res , vol.12 , Issue.1 , pp. 314-320
    • Mao, J.T.1    Fishbein, M.C.2    Adams, B.3
  • 89
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therap
    • Jun 4
    • Paez JG, Janne PA, Lee JC et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therap. Science Jun 4, 2004; 304(5676):1497-500.
    • (2004) Science , vol.304 , Issue.5676 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 90
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitini
    • May 20
    • Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitini. N Engl J Med May 20, 2004; 350(21):2129-39.
    • (2004) N Engl J Med , vol.350 , Issue.21 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 91
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotini
    • Sep 7
    • Pao W, Miller V, Zakowski M et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotini. Proc Natl Acad Sci U S A Sep 7, 2004; 101(36):13306-11.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.36 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 92
    • 19944426858 scopus 로고    scopus 로고
    • High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwa
    • Dec 15
    • Huang SF, Liu HP, Li LH et al. High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwa. Clin Cancer Res Dec 15, 2004; 10(24):8195-203.
    • (2004) Clin Cancer Res , vol.10 , Issue.24 , pp. 8195-8203
    • Huang, S.F.1    Liu, H.P.2    Li, L.H.3
  • 93
    • 10844231985 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implication
    • Dec 15
    • Kosaka T, Yatabe Y, Endoh H, Kuwano H, Takahashi T, Mitsudomi T. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implication. Cancer Res Dec 15, 2004; 64(24):8919-23.
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 8919-8923
    • Kosaka, T.1    Yatabe, Y.2    Endoh, H.3    Kuwano, H.4    Takahashi, T.5    Mitsudomi, T.6
  • 94
    • 19944433797 scopus 로고    scopus 로고
    • The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancer
    • Feb 1
    • Tokumo M, Toyooka S, Kiura K et al. The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancer. Clin Cancer Res Feb 1, 2005; 11(3):1167-73.
    • (2005) Clin Cancer Res , vol.11 , Issue.3 , pp. 1167-1173
    • Tokumo, M.1    Toyooka, S.2    Kiura, K.3
  • 95
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancer
    • Mar 2
    • Shigematsu H, Lin L, Takahashi T et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancer. J Natl Cancer Inst Mar 2, 2005; 97(5):339-46.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.5 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 96
    • 20144386787 scopus 로고    scopus 로고
    • Somatic mutations of the HER2 kinase domain in lung adenocarcinoma
    • Mar 1
    • Shigematsu H, Takahashi T, Nomura M et al. Somatic mutations of the HER2 kinase domain in lung adenocarcinoma. Cancer Res Mar 1, 2005; 65(5):1642-6.
    • (2005) Cancer Res , vol.65 , Issue.5 , pp. 1642-1646
    • Shigematsu, H.1    Takahashi, T.2    Nomura, M.3
  • 97
    • 19944427851 scopus 로고    scopus 로고
    • Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cance
    • Jan 1
    • Amann J, Kalyankrishna S, Massion PP et al. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cance. Cancer Res Jan 1, 2005; 65(1):226-35.
    • (2005) Cancer Res , vol.65 , Issue.1 , pp. 226-235
    • Amann, J.1    Kalyankrishna, S.2    Massion, P.P.3
  • 98
    • 20444498630 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cance
    • May 4
    • Cappuzzo F, Hirsch FR, Rossi E et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cance. J Natl Cancer Inst May 4, 2005; 97(9):643-55.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.9 , pp. 643-655
    • Cappuzzo, F.1    Hirsch, F.R.2    Rossi, E.3
  • 99
    • 27244443759 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Stud
    • Oct 1
    • Hirsch FR, Varella-Garcia M, McCoy J et al. Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Stud. J Clin Oncol Oct 1, 2005; 23(28):6838-45.
    • (2005) J Clin Oncol , vol.23 , Issue.28 , pp. 6838-6845
    • Hirsch, F.R.1    Varella-Garcia, M.2    McCoy, J.3
  • 100
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancer-molecular and clinical predictors of outcom
    • Jul 14
    • Tsao MS, Sakurada A, Cutz JC et al. Erlotinib in lung cancer-molecular and clinical predictors of outcom. N Engl J Med Jul 14, 2005; 353(2):133-44.
    • (2005) N Engl J Med , vol.353 , Issue.2 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3
  • 101
    • 17744371335 scopus 로고    scopus 로고
    • EGFR mutation is specific for terminal respiratory unit type adenocarcinoma
    • Yatabe Y, Kosaka T, Takahashi T, Mitsudomi T. EGFR mutation is specific for terminal respiratory unit type adenocarcinoma. Am J Surg Pathol May 2005; 29(5):633-9.
    • (2005) Am J Surg Pathol May , vol.29 , Issue.5 , pp. 633-639
    • Yatabe, Y.1    Kosaka, T.2    Takahashi, T.3    Mitsudomi, T.4
  • 102
    • 24744443517 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene in atypical adenomatous hyperplasia and bronchioloalveolar carcinoma of the lung
    • Yoshida Y, Shibata T, Kokubu A et al. Mutations of the epidermal growth factor receptor gene in atypical adenomatous hyperplasia and bronchioloalveolar carcinoma of the lung. Lung Cancer Oct 2005; 50(1):1-8.
    • (2005) Lung Cancer Oct , vol.50 , Issue.1 , pp. 1-8
    • Yoshida, Y.1    Shibata, T.2    Kokubu, A.3


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