Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smokers

Cancer Research

Volumn 62, Issue 2, 2002, Pages 351-355

  Soria, Jean Charles ^a   Rodriguez, Marivonne ^a   Liu, Diane D ^a   Jack Lee, J ^a   Ki Hong, Waun ^a   Mao, Li ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GLUTATHIONE TRANSFERASE; PROTEIN KINASE; PROTEIN P16;

ADULT; AGED; ANAMNESIS; ARTICLE; BRONCHUS BIOPSY; CIGARETTE SMOKING; CORRELATION ANALYSIS; FEMALE; FOLLOW UP; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION;

ADULT; AGE FACTORS; AGED; APOPTOSIS REGULATORY PROTEINS; BRONCHI; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CPG ISLANDS; DNA METHYLATION; FEMALE; GENES, P16; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; LUNG NEOPLASMS; MALE; MICROVILLI; MIDDLE AGED; PROMOTER REGIONS (GENETICS); SMOKING; SMOKING CESSATION; TUMOR MARKERS, BIOLOGICAL;

EID: 0037081176     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Cancer statistics 2001
2. Revision in the international system for staging of lung cancer
3. Early detection and prevention of lung cancer
4. Alterations in DNA methylation: A fundamental aspect of neoplasia
5. Methylation-specific PCR. A novel PCR assay for methylation status of CpG islands
6. ink4n is an early event in lung cancer and a potential biomarker for early diagnosis
7. Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer
8. Inactivation of glutathione S-transferase PI gene by promoter hypermethylation in human neoplasia
9. INK4n promoter hypermethylation, p53 mutation, and K-ras mutation in exfoliative material mark the development of lung cancer in symptomatic chronic smokers
10. Predicting lung cancer by detecting aberrant promoter methylation in sputum
11. A gene hypermethylation profile of human cancer
12. Aberrant promoter methylation of multiple genes in non-small cell lung cancers
13. Promoter methylation of DAP-kinase: Association with advanced stage in non-small cell lung cancer
14. INK4 gene inactivation by hypermethylation in lung cancer during the process of metastasis and its relation to the status of p53
15. Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer
16. Methylation of the oestrogen receptor CpG island links aging and neoplasia in human colon
17. CpG island methylator phenotype in colorectal cancer
18. INK4a and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer
19. Role of the INK4a locus in tumor suppression and cell mortality
20. The dose-response relationship between cigarette consumption, biochemical markers, and risk of lung cancer
21. Mass screening for lung cancer with mobile spiral computed tomography scanner
22. Effects of N-(4-hydroxyphenyl) retinamide on hTERT expression in the bronchial epithelium of cigarette smokers