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Volumn 65, Issue 1, 2005, Pages 226-235

Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEFITINIB; TRASTUZUMAB;

EID: 19944427851     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (398)

References (23)
  • 1
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • Rusch V, Baselga J, Cordon-Cardo C, et al. Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 1993;53:2379-85.
    • (1993) Cancer Res , vol.53 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3
  • 2
    • 0028913802 scopus 로고
    • Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia and coexpression precedes squamous cell carcinoma development
    • Rusch V, Klimstra D, Linkov I, Dmitrovsky E. Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia and coexpression precedes squamous cell carcinoma development. Cancer Res 1995;55:1365-72.
    • (1995) Cancer Res , vol.55 , pp. 1365-1372
    • Rusch, V.1    Klimstra, D.2    Linkov, I.3    Dmitrovsky, E.4
  • 3
    • 0036817040 scopus 로고    scopus 로고
    • Epithelial growth factor receptor interacting agents
    • Baselga J, Albanell J. Epithelial growth factor receptor interacting agents. Hematol Oncol Clin North Am 2002;16:1041-63.
    • (2002) Hematol Oncol Clin North Am , vol.16 , pp. 1041-1063
    • Baselga, J.1    Albanell, J.2
  • 4
    • 0012381722 scopus 로고    scopus 로고
    • Multiinstitutional randomized phase 11 trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
    • Fukuoka M, Yano S, Giaccone G, et al. Multiinstitutional randomized phase 11 trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 2003;21:2237-46.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 5
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003;290:2149-58.
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 6
    • 0142119289 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in non-small-cel] lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
    • Hirsch FR, Varella-Garcia M, Bunn PA Jr, et al. Epidermal growth factor receptor in non-small-cel] lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003;21:3798-807.
    • (2003) J Clin Oncol , vol.21 , pp. 3798-3807
    • Hirsch, F.R.1    Varella-Garcia, M.2    Bunn Jr., P.A.3
  • 7
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639-48.
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 8
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 9
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 10
    • 5644303684 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of erlotinib in patients with advanced non-small cell lung cancer following failure of 1st line or 2nd line chemotherapy
    • Shepherd FA, Periera J, Ciuleanu TE, et al. A randomized, placebo-controlled trial of erlotinib in patients with advanced non-small cell lung cancer following failure of 1st line or 2nd line chemotherapy [abstract 7022]. Proc Am Soc Clin Oncol 2004.
    • (2004) Proc Am Soc Clin Oncol
    • Shepherd, F.A.1    Periera, J.2    Ciuleanu, T.E.3
  • 11
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hun HD, Horton RM, Pullen JK, Pease LR. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 1989;77:51-9.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hun, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 12
    • 0037133672 scopus 로고    scopus 로고
    • Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis
    • Liu S, Liu W, Jakubczak JL, et al. Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis. Proc Natl Acad Sci U S A 2002;99:3770-5.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3770-3775
    • Liu, S.1    Liu, W.2    Jakubczak, J.L.3
  • 13
    • 85047696060 scopus 로고    scopus 로고
    • Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu
    • Montagna C, Andrechek ER, Padilla-Nash H, Muller WJ, Ried T. Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu. Oncogene 2002;21:890-8.
    • (2002) Oncogene , vol.21 , pp. 890-898
    • Montagna, C.1    Andrechek, E.R.2    Padilla-Nash, H.3    Muller, W.J.4    Ried, T.5
  • 14
    • 0032823523 scopus 로고    scopus 로고
    • Genome-wide analysis of DNA copy-number changes using cDNA microarrays
    • Pollack JR, Perou CM, Alizadeh AA, et al. Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet 1999;23:41-6.
    • (1999) Nat Genet , vol.23 , pp. 41-46
    • Pollack, J.R.1    Perou, C.M.2    Alizadeh, A.A.3
  • 15
    • 13844250828 scopus 로고    scopus 로고
    • Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
    • Pollack JR, Sorlie T, Perou CM, et al. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proc Natl Acad Sci U S A 2002;99:12963-8.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12963-12968
    • Pollack, J.R.1    Sorlie, T.2    Perou, C.M.3
  • 16
    • 0037145061 scopus 로고    scopus 로고
    • Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
    • Schlessinger J. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 2002;110:669-72.
    • (2002) Cell , vol.110 , pp. 669-672
    • Schlessinger, J.1
  • 17
    • 4143066760 scopus 로고    scopus 로고
    • Gefitinib-sensitizing EGFR mutations in lug cancer activate antiapoptotic pathways
    • Epub 2004 Jul 29
    • Sordella R, Bell DW, Haber DA, Settleman J. Gefitinib-sensitizing EGFR mutations in lug cancer activate antiapoptotic pathways. Science 2004;304:. Epub 2004 Jul 29.
    • (2004) Science , vol.304
    • Sordella, R.1    Bell, D.W.2    Haber, D.A.3    Settleman, J.4
  • 18
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004;101:13306-11.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 20
    • 0037616593 scopus 로고    scopus 로고
    • Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors
    • Bianco R, Shin I, Ritter CA, et al. Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors. Oncogene 2003;22:2812-22.
    • (2003) Oncogene , vol.22 , pp. 2812-2822
    • Bianco, R.1    Shin, I.2    Ritter, C.A.3
  • 21
    • 0141960451 scopus 로고    scopus 로고
    • Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3′-kinase/Akt pathway signaling
    • She QB, Solit D, Basso A, Moasser MM. Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3′-kinase/Akt pathway signaling. Clin Cancer Res 2003;9:4340-6.
    • (2003) Clin Cancer Res , vol.9 , pp. 4340-4346
    • She, Q.B.1    Solit, D.2    Basso, A.3    Moasser, M.M.4
  • 22
    • 0037429692 scopus 로고    scopus 로고
    • Trafficking of the ErbB receptors and its influence on signaling
    • Wiley HS. Trafficking of the ErbB receptors and its influence on signaling. Exp Cell Res 2003;284:78-88.
    • (2003) Exp Cell Res , vol.284 , pp. 78-88
    • Wiley, H.S.1
  • 23
    • 4444238981 scopus 로고    scopus 로고
    • TRIBUTE - A phase III trial of erlotinib HCl combined with carboplatinum and paclitaxel chemotherapy in advanced non-small cell lung cancer
    • Herbst RS, Prager D, Hermann R, et al. TRIBUTE-a phase III trial of erlotinib HCl combined with carboplatinum and paclitaxel chemotherapy in advanced non-small cell lung cancer [abstract 7011]. Proc Am Soc Clin Oncol 2004.
    • (2004) Proc Am Soc Clin Oncol
    • Herbst, R.S.1    Prager, D.2    Hermann, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.